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Identifier: 15645799

GI number: 15645799

Start: 1254325

End: 1255500

Strand: Reverse

Name: Not Available

Synonym: HP1185

Alternate gene names: 15645799

Gene position: 1255500-1254325 (Counterclockwise)

Preceding gene: 15645801

Following gene: 15645798

Centisome position: 75.28

GC content: 44.39

Gene sequence:

>1176_bases
ATGATGATAACCAAACAATCGTATCAAAAGTTCGCCTTAATGCGGGTTTTTGTGTTTTCGCTTTCGGCGTTTATTTTTAA
CACCACGGAGTTTGTCCCTGTCGCGCTTCTGTCAGATATTGCGAAAAGCTTTGAAATGGAGAGCGCAACGGTGGGGCTTA
TGATCACTGCTTATGCATGGGTGGTGTCTCTTGGCTCATTGCCCTTGATGCTGCTTAGCGCTAAAATTGAAAGGAAACGC
TTATTGCTTTTTCTTTTCGCCCTTTTTATTCTCAGCCATATCCTTTCAGCGTTAGCGTGGAATTTTTGGGTGCTACTCCT
TTCTCGTATGGGTATCGCTTTTGCCCACTCTATTTTTTGGTCCATCACGGCTTCTTTAGTCATTCGTGTCGCGCCAAGAA
ATAAAAAACAACAGGCCTTAGGGCTGTTAGCGTTAGGGAGTTCGTTAGCGATGATTTTAGGGTTGCCGCTTGGGAGGATC
ATTGGGCAAATTCTAGATTGGCGTTCCACTTTTGGCGTGATCGGGGGCGTTGCGACCCTTATAGCGTTGCTTATGTGGAA
ATTGCTCCCGCATCTACCCAGTAGAAACGCAGGCACGCTCGCAAGTGTCCCTGTATTAATGAAACGGCCGCTTTTAATGG
GGATTTATTTGCTTGTGATCATGGTCATCTCTGGGCATTTCACCACTTATAGTTATATTGAGCCTTTTATCATTCAAATC
AGCCAATTTTCTCCTGACATTACAACGCTAATGTTGTTTGTGTTTGGGTTAGCGGGCGTGGTGGGGAGTTTTTTGTTCGG
CCGTTTGTATGCAAAAAATTCAAGAAAATTTATCGCTTTTGCGATGGTTTTAGTCATTTGCCCGCAACTCTTGCTTTTTG
TGTTTAAAAACTTAGAGTGGGTGGTTTTCTTGCAAATTTTCTTATGGGGGATTGGGATCACTTCGCTTGGGATTTCCTTG
CAAATGAGGGTGTTGCAGCTTGCGCCGGATGCCACGGATGTTGCGAGTGCGATTTACTCAGGGAGCTATAATGTGGGGAT
TGGATCAGGAGCGCTGTTTGGCAGTATTGTGATCCACCAACTAGGGCTAGGATATATTGGCTTTGTGGGTGGGGCTTTAG
GTTTGTTGGCGCTCTTTTGGCTTAGATTCATTACGATAAAGTTTAAAAAAACATAA

Upstream 100 bases:

>100_bases
AATATTTGTTTTAACCAGCTCCTAATTTACAAGCGATTAAAATTTTTGTCTTATAATTCAAGCTTTCAAATTGAATAAAA
TTCAACCCCTTAAGATTTAA

Downstream 100 bases:

>100_bases
AGAGCGTTAAAAGGATTAGCCCAATAAAGGAGAATCCCTTTCGCACTAAAAACCATTTTTTAATGATACCGCTTAATAAC
CGCACTAACGGATAGATTGT

Product: sugar efflux transporter

Products: arabinose [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MMITKQSYQKFALMRVFVFSLSAFIFNTTEFVPVALLSDIAKSFEMESATVGLMITAYAWVVSLGSLPLMLLSAKIERKR
LLLFLFALFILSHILSALAWNFWVLLLSRMGIAFAHSIFWSITASLVIRVAPRNKKQQALGLLALGSSLAMILGLPLGRI
IGQILDWRSTFGVIGGVATLIALLMWKLLPHLPSRNAGTLASVPVLMKRPLLMGIYLLVIMVISGHFTTYSYIEPFIIQI
SQFSPDITTLMLFVFGLAGVVGSFLFGRLYAKNSRKFIAFAMVLVICPQLLLFVFKNLEWVVFLQIFLWGIGITSLGISL
QMRVLQLAPDATDVASAIYSGSYNVGIGSGALFGSIVIHQLGLGYIGFVGGALGLLALFWLRFITIKFKKT

Sequences:

>Translated_391_residues
MMITKQSYQKFALMRVFVFSLSAFIFNTTEFVPVALLSDIAKSFEMESATVGLMITAYAWVVSLGSLPLMLLSAKIERKR
LLLFLFALFILSHILSALAWNFWVLLLSRMGIAFAHSIFWSITASLVIRVAPRNKKQQALGLLALGSSLAMILGLPLGRI
IGQILDWRSTFGVIGGVATLIALLMWKLLPHLPSRNAGTLASVPVLMKRPLLMGIYLLVIMVISGHFTTYSYIEPFIIQI
SQFSPDITTLMLFVFGLAGVVGSFLFGRLYAKNSRKFIAFAMVLVICPQLLLFVFKNLEWVVFLQIFLWGIGITSLGISL
QMRVLQLAPDATDVASAIYSGSYNVGIGSGALFGSIVIHQLGLGYIGFVGGALGLLALFWLRFITIKFKKT
>Mature_391_residues
MMITKQSYQKFALMRVFVFSLSAFIFNTTEFVPVALLSDIAKSFEMESATVGLMITAYAWVVSLGSLPLMLLSAKIERKR
LLLFLFALFILSHILSALAWNFWVLLLSRMGIAFAHSIFWSITASLVIRVAPRNKKQQALGLLALGSSLAMILGLPLGRI
IGQILDWRSTFGVIGGVATLIALLMWKLLPHLPSRNAGTLASVPVLMKRPLLMGIYLLVIMVISGHFTTYSYIEPFIIQI
SQFSPDITTLMLFVFGLAGVVGSFLFGRLYAKNSRKFIAFAMVLVICPQLLLFVFKNLEWVVFLQIFLWGIGITSLGISL
QMRVLQLAPDATDVASAIYSGSYNVGIGSGALFGSIVIHQLGLGYIGFVGGALGLLALFWLRFITIKFKKT

Specific function: Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites [H]

COG id: COG2814

COG function: function code G; Arabinose efflux permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family [H]

Homologues:

Organism=Escherichia coli, GI1787808, Length=379, Percent_Identity=50.6596306068602, Blast_Score=340, Evalue=8e-95,
Organism=Escherichia coli, GI1787947, Length=328, Percent_Identity=28.6585365853659, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI145693198, Length=362, Percent_Identity=25.1381215469613, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1786595, Length=349, Percent_Identity=26.0744985673352, Blast_Score=108, Evalue=7e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43111; Mature: 43111

Theoretical pI: Translated: 10.86; Mature: 10.86

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMITKQSYQKFALMRVFVFSLSAFIFNTTEFVPVALLSDIAKSFEMESATVGLMITAYAW
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
VVSLGSLPLMLLSAKIERKRLLLFLFALFILSHILSALAWNFWVLLLSRMGIAFAHSIFW
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SITASLVIRVAPRNKKQQALGLLALGSSLAMILGLPLGRIIGQILDWRSTFGVIGGVATL
HHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
IALLMWKLLPHLPSRNAGTLASVPVLMKRPLLMGIYLLVIMVISGHFTTYSYIEPFIIQI
HHHHHHHHHHCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
SQFSPDITTLMLFVFGLAGVVGSFLFGRLYAKNSRKFIAFAMVLVICPQLLLFVFKNLEW
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHH
VVFLQIFLWGIGITSLGISLQMRVLQLAPDATDVASAIYSGSYNVGIGSGALFGSIVIHQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
LGLGYIGFVGGALGLLALFWLRFITIKFKKT
HCCHHHHHHHHHHHHHHHHHHHHHHHHEECC
>Mature Secondary Structure
MMITKQSYQKFALMRVFVFSLSAFIFNTTEFVPVALLSDIAKSFEMESATVGLMITAYAW
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
VVSLGSLPLMLLSAKIERKRLLLFLFALFILSHILSALAWNFWVLLLSRMGIAFAHSIFW
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SITASLVIRVAPRNKKQQALGLLALGSSLAMILGLPLGRIIGQILDWRSTFGVIGGVATL
HHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
IALLMWKLLPHLPSRNAGTLASVPVLMKRPLLMGIYLLVIMVISGHFTTYSYIEPFIIQI
HHHHHHHHHHCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
SQFSPDITTLMLFVFGLAGVVGSFLFGRLYAKNSRKFIAFAMVLVICPQLLLFVFKNLEW
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHH
VVFLQIFLWGIGITSLGISLQMRVLQLAPDATDVASAIYSGSYNVGIGSGALFGSIVIHQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
LGLGYIGFVGGALGLLALFWLRFITIKFKKT
HCCHHHHHHHHHHHHHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: arabinose [Cytoplasm]; Proton [Periplasm] [C]

Specific reaction: arabinose [Cytoplasm] + Proton [Periplasm] = arabinose [Periplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA