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Identifier: 15645798

GI number: 15645798

Start: 1252785

End: 1254164

Strand: Reverse

Name: Not Available

Synonym: HP1184

Alternate gene names: NA

Gene position: 1254164-1252785 (Counterclockwise)

Preceding gene: 15645799

Following gene: 15645797

Centisome position: 75.2

GC content: 39.35

Gene sequence:

>1380_bases
ATGCTAATAAAAAAGATTGATTTGCATAAAGATCCGATAAGAAAGCTCTTTTTTTATTATTTTATCCCTTTAGCTTTTTC
TATGATTTCACTTTCCACTTACTCTATGATAGATGGCATGTTTGTGGGCAAGAAACTGGGTAAAGAAGCTATCGCTGCAG
TCAATATCGCATGGCCTATTTTTCCAGGGCTCATTGCGTATGAATTGCTTTTTGGTTTTGGGGCAGCGAGTATTGTGGGG
TATTTTTTGGGTCAAAATAAAACCCATAGGGCTAGGCTTGTGTTTAGCAGCGTGTTTTATTTTGTCGCTATAAGTGCCTT
TATTTTGAGCATGGCGTTATTGCCTTTTAGCGAAACTATCGCGCGTTTTTTTGGGAGCAATGACGCTTTATTGAGCATGT
CCAAACGCTACATTGAAATCATTTTAATGGGCGCGGTTTTTATGGTTTTGCACCCTTTGGCGGATGTTTTTGTGGTGAAT
GACAAACGCCCCATTTTAGCGATGGTAGCGATGCTGATTGGCTCGTTAGCGAATATCTTTTTCAACTACTTGTTTATTTT
TGTTTTAAAAGTGGGGGTTCAAGGCAGCGCGATAGCCACCGTGATAGGGCATGCGATAGGGGTTTTAGTCTTAATGCAGC
ATTTTTGGCGCAAAAAAGGGCAATTGTATTTCATCAAACGATTTTCCTTGTCTTCAGTCATTTCTTCAGCTAAAAGCGGC
GTGCCTCAAAGCACGGCAGAATTTAGTGCTTCTGTTATGATTTTGTTGTTTAATACCGCTATCATGCACACGGCTGGGGA
AAGGTTTGTAAGCATGTATGGGATCGTTATGTATAATGCGATTATCTTTTTTACGACTTTGTTTGCGATTTCTCAAGGCA
TCCAACCGATTGCGAGCTTTAGCTATGGGGCTAGAAATTTAGAGCGCGTGAAAGAGGTGTTTGTCTTTGGTTTGAAAGCA
GCGTTTTGTATAGGGATTGTTTTCTATGGCGCTTATTATTTTTTAGATGAATTTTTAATCAAGCTTTATTTGCAGCCAAG
CGAACAAGACCCCCTTTTTATGCAAGAGACTAAAAGGGCGATGAATATTTATTATGTGGGCTATATTTTCTTAGGCATGA
CTTTGTTGTGCGCGGTGTTTTTCCAATCCATCCAACGCACCAAAAGTTCGTTTATCATCACCCTTTCACACACGCTGGGG
TTTATCGTTATTCTATTGCCGATTTTAAGTCATTTCTATGGGATTAATGGCGTTTGGGTAACTTACCCCATTGCGCAATT
TTTAGCGTTTTTAGTAGCGTTAGGGGTAACTTATTACGAAATCAAAAAAGGGGTTTTTACCACTTATAAAGAGAAAAACC
CTATCGCTTTGAAAACTTAA

Upstream 100 bases:

>100_bases
TAATGATACCGCTTAATAACCGCACTAACGGATAGATTGTCTCTCTTTTTATGTTAAAATAGAAAAATTTGTCATAAATT
TTAGGTGGTGTGTGGTTTAA

Downstream 100 bases:

>100_bases
CCAATAAATAAGGTAAAATTAAGACATGCATGCAGAATTTTTCACTTTCGCGCTCATCATGCTTTTAATTGTGATGGCCC
CTTATATGTCTAGAATCTCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MLIKKIDLHKDPIRKLFFYYFIPLAFSMISLSTYSMIDGMFVGKKLGKEAIAAVNIAWPIFPGLIAYELLFGFGAASIVG
YFLGQNKTHRARLVFSSVFYFVAISAFILSMALLPFSETIARFFGSNDALLSMSKRYIEIILMGAVFMVLHPLADVFVVN
DKRPILAMVAMLIGSLANIFFNYLFIFVLKVGVQGSAIATVIGHAIGVLVLMQHFWRKKGQLYFIKRFSLSSVISSAKSG
VPQSTAEFSASVMILLFNTAIMHTAGERFVSMYGIVMYNAIIFFTTLFAISQGIQPIASFSYGARNLERVKEVFVFGLKA
AFCIGIVFYGAYYFLDEFLIKLYLQPSEQDPLFMQETKRAMNIYYVGYIFLGMTLLCAVFFQSIQRTKSSFIITLSHTLG
FIVILLPILSHFYGINGVWVTYPIAQFLAFLVALGVTYYEIKKGVFTTYKEKNPIALKT

Sequences:

>Translated_459_residues
MLIKKIDLHKDPIRKLFFYYFIPLAFSMISLSTYSMIDGMFVGKKLGKEAIAAVNIAWPIFPGLIAYELLFGFGAASIVG
YFLGQNKTHRARLVFSSVFYFVAISAFILSMALLPFSETIARFFGSNDALLSMSKRYIEIILMGAVFMVLHPLADVFVVN
DKRPILAMVAMLIGSLANIFFNYLFIFVLKVGVQGSAIATVIGHAIGVLVLMQHFWRKKGQLYFIKRFSLSSVISSAKSG
VPQSTAEFSASVMILLFNTAIMHTAGERFVSMYGIVMYNAIIFFTTLFAISQGIQPIASFSYGARNLERVKEVFVFGLKA
AFCIGIVFYGAYYFLDEFLIKLYLQPSEQDPLFMQETKRAMNIYYVGYIFLGMTLLCAVFFQSIQRTKSSFIITLSHTLG
FIVILLPILSHFYGINGVWVTYPIAQFLAFLVALGVTYYEIKKGVFTTYKEKNPIALKT
>Mature_459_residues
MLIKKIDLHKDPIRKLFFYYFIPLAFSMISLSTYSMIDGMFVGKKLGKEAIAAVNIAWPIFPGLIAYELLFGFGAASIVG
YFLGQNKTHRARLVFSSVFYFVAISAFILSMALLPFSETIARFFGSNDALLSMSKRYIEIILMGAVFMVLHPLADVFVVN
DKRPILAMVAMLIGSLANIFFNYLFIFVLKVGVQGSAIATVIGHAIGVLVLMQHFWRKKGQLYFIKRFSLSSVISSAKSG
VPQSTAEFSASVMILLFNTAIMHTAGERFVSMYGIVMYNAIIFFTTLFAISQGIQPIASFSYGARNLERVKEVFVFGLKA
AFCIGIVFYGAYYFLDEFLIKLYLQPSEQDPLFMQETKRAMNIYYVGYIFLGMTLLCAVFFQSIQRTKSSFIITLSHTLG
FIVILLPILSHFYGINGVWVTYPIAQFLAFLVALGVTYYEIKKGVFTTYKEKNPIALKT

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 51617; Mature: 51617

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIKKIDLHKDPIRKLFFYYFIPLAFSMISLSTYSMIDGMFVGKKLGKEAIAAVNIAWPI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FPGLIAYELLFGFGAASIVGYFLGQNKTHRARLVFSSVFYFVAISAFILSMALLPFSETI
HHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARFFGSNDALLSMSKRYIEIILMGAVFMVLHPLADVFVVNDKRPILAMVAMLIGSLANIF
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHH
FNYLFIFVLKVGVQGSAIATVIGHAIGVLVLMQHFWRKKGQLYFIKRFSLSSVISSAKSG
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHCC
VPQSTAEFSASVMILLFNTAIMHTAGERFVSMYGIVMYNAIIFFTTLFAISQGIQPIASF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
SYGARNLERVKEVFVFGLKAAFCIGIVFYGAYYFLDEFLIKLYLQPSEQDPLFMQETKRA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
MNIYYVGYIFLGMTLLCAVFFQSIQRTKSSFIITLSHTLGFIVILLPILSHFYGINGVWV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEEHHHHHHHHHHHHHHHHHHCCCCEEH
TYPIAQFLAFLVALGVTYYEIKKGVFTTYKEKNPIALKT
HHHHHHHHHHHHHHCCHHHHHHHCHHHHCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHCCHHHHHHHCHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]