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Identifier: 15645691

GI number: 15645691

Start: 1135905

End: 1136900

Strand: Reverse

Name: Not Available

Synonym: HP1077

Alternate gene names: 15645691

Gene position: 1136900-1135905 (Counterclockwise)

Preceding gene: 15645692

Following gene: 15645689

Centisome position: 68.16

GC content: 42.37

Gene sequence:

>996_bases
GTGAAATTGTGGTTTCCTTATTTTTTAGCGATTGTGTTCTTGCATGCATTGGGTTTAGCGTTGCTCTTTATGGCCAATAA
CGCTTCGTTTTATGCGGCGGCGTCTATGGCCTACATGCTAGGGGCAAAGCATGCGTTTGATGCGGATCACATCGCTTGCA
TAGATAACACCATTAGAAAGCTCACCCAACAAGGCAAAAACGCCTATGGTGTGGGGTTTTACTTTTCTATGGGGCATTCA
AGCGTGGTGATTTTAATGACCATCATCAGCGCGTTTGCGATCGCTTGGGCTAAAGAACACACGCCGATGCTAGAAGAAAT
AGGGGGGGTAGTGGGGACTTTAGTTTCTGGGCTTTTTTTGCTCATTATAGGGCTATTGAATGCGATTATTCTCTTGGATT
TATTAAAAATATTCAAAAAATCGCACTCTAATGAAAGCCTAAGCCAGCAACAAAATGAAGAGATCGAGCGGCTCTTAACG
AGTAGGGGCTTGCTCAACCGCTTTTTTAAACCCTTGTTTAATTTTGTCTCCAAGTCGTGGCATATTTATCCTATCGGTTT
TCTTTTTGGGCTGGGTTTTGATACCGCTAGTGAAATCGCGCTTTTGGCCCTCTCTAGCAGCGCGATTAAAGTGAGTATGG
TGGGCATGCTCTCTTTACCCATTCTTTTTGCCGCTGGCATGAGTTTGTTTGACACTTTAGATGGGGCGTTCATGCTCAAG
GCGTATGACTGGGCGTTCAAAACCCCTTTAAGAAAAATCTATTACAATATCTCTATCACGGCCTTAAGCGTGTTTATCGC
GCTCTTTATTGGCTTGATTGAGCTTTTTCAAGTCGTTAGCGAGAAACTCCATTTAAAATTTGAAAACCGCCTTTTAAGAG
CCTTACAAAGCCTGGAATTTACAGACTTGGGCTATTACTTGGTGGGCTTATTTGTAATAGCGTTTCTAGGATCGTTCTTT
TTATGGAAAATCAAATTTTCTAAACTAGAGAGCTGA

Upstream 100 bases:

>100_bases
ATTTGCAGAAAATAATCAAAAAACAAATCCTAAAATTTTCTAATTTAACAAAATATATTACAATTACCAAAAAAGTATTA
TTTTTCTTAAAAGGTGCGCT

Downstream 100 bases:

>100_bases
ATTCTAAGCCCTCAAATTATCGCTTAATAAATCTTTAAGGCTTTGATTTGAAAAACTTGGCATGAAGGCTTTAGGGTTTG
AAAGGCTTTCACTCAAATAA

Product: nickel transport protein (nixA)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MKLWFPYFLAIVFLHALGLALLFMANNASFYAAASMAYMLGAKHAFDADHIACIDNTIRKLTQQGKNAYGVGFYFSMGHS
SVVILMTIISAFAIAWAKEHTPMLEEIGGVVGTLVSGLFLLIIGLLNAIILLDLLKIFKKSHSNESLSQQQNEEIERLLT
SRGLLNRFFKPLFNFVSKSWHIYPIGFLFGLGFDTASEIALLALSSSAIKVSMVGMLSLPILFAAGMSLFDTLDGAFMLK
AYDWAFKTPLRKIYYNISITALSVFIALFIGLIELFQVVSEKLHLKFENRLLRALQSLEFTDLGYYLVGLFVIAFLGSFF
LWKIKFSKLES

Sequences:

>Translated_331_residues
MKLWFPYFLAIVFLHALGLALLFMANNASFYAAASMAYMLGAKHAFDADHIACIDNTIRKLTQQGKNAYGVGFYFSMGHS
SVVILMTIISAFAIAWAKEHTPMLEEIGGVVGTLVSGLFLLIIGLLNAIILLDLLKIFKKSHSNESLSQQQNEEIERLLT
SRGLLNRFFKPLFNFVSKSWHIYPIGFLFGLGFDTASEIALLALSSSAIKVSMVGMLSLPILFAAGMSLFDTLDGAFMLK
AYDWAFKTPLRKIYYNISITALSVFIALFIGLIELFQVVSEKLHLKFENRLLRALQSLEFTDLGYYLVGLFVIAFLGSFF
LWKIKFSKLES
>Mature_331_residues
MKLWFPYFLAIVFLHALGLALLFMANNASFYAAASMAYMLGAKHAFDADHIACIDNTIRKLTQQGKNAYGVGFYFSMGHS
SVVILMTIISAFAIAWAKEHTPMLEEIGGVVGTLVSGLFLLIIGLLNAIILLDLLKIFKKSHSNESLSQQQNEEIERLLT
SRGLLNRFFKPLFNFVSKSWHIYPIGFLFGLGFDTASEIALLALSSSAIKVSMVGMLSLPILFAAGMSLFDTLDGAFMLK
AYDWAFKTPLRKIYYNISITALSVFIALFIGLIELFQVVSEKLHLKFENRLLRALQSLEFTDLGYYLVGLFVIAFLGSFF
LWKIKFSKLES

Specific function: High-affinity nickel intake protein. Imports nickel ions in an energy-dependent fashion. Necessary for the expression of catalytically active urease [H]

COG id: COG3376

COG function: function code P; High-affinity nickel permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NiCoT transporter (TC 2.A.52) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004688
- InterPro:   IPR011541 [H]

Pfam domain/function: PF03824 NicO [H]

EC number: NA

Molecular weight: Translated: 37034; Mature: 37034

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLWFPYFLAIVFLHALGLALLFMANNASFYAAASMAYMLGAKHAFDADHIACIDNTIRK
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
LTQQGKNAYGVGFYFSMGHSSVVILMTIISAFAIAWAKEHTPMLEEIGGVVGTLVSGLFL
HHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LIIGLLNAIILLDLLKIFKKSHSNESLSQQQNEEIERLLTSRGLLNRFFKPLFNFVSKSW
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
HIYPIGFLFGLGFDTASEIALLALSSSAIKVSMVGMLSLPILFAAGMSLFDTLDGAFMLK
EEEEHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
AYDWAFKTPLRKIYYNISITALSVFIALFIGLIELFQVVSEKLHLKFENRLLRALQSLEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
TDLGYYLVGLFVIAFLGSFFLWKIKFSKLES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLWFPYFLAIVFLHALGLALLFMANNASFYAAASMAYMLGAKHAFDADHIACIDNTIRK
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
LTQQGKNAYGVGFYFSMGHSSVVILMTIISAFAIAWAKEHTPMLEEIGGVVGTLVSGLFL
HHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LIIGLLNAIILLDLLKIFKKSHSNESLSQQQNEEIERLLTSRGLLNRFFKPLFNFVSKSW
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
HIYPIGFLFGLGFDTASEIALLALSSSAIKVSMVGMLSLPILFAAGMSLFDTLDGAFMLK
EEEEHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
AYDWAFKTPLRKIYYNISITALSVFIALFIGLIELFQVVSEKLHLKFENRLLRALQSLEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
TDLGYYLVGLFVIAFLGSFFLWKIKFSKLES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]