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Identifier: 15645557

GI number: 15645557

Start: 1001142

End: 1002275

Strand: Reverse

Name: Not Available

Synonym: HP0941

Alternate gene names: 15645557

Gene position: 1002275-1001142 (Counterclockwise)

Preceding gene: 15645558

Following gene: 15645556

Centisome position: 60.09

GC content: 40.19

Gene sequence:

>1134_bases
ATGTTAAAAAGGGCGAGTTTTGTAGAAGTGGATACCGCTTCTTTAAGGCATAATTTTAGCGCAGTCAAAAGCATTGTCCC
TAAAGACGCTTGTGTCATGGCGGTTGTCAAGGCGAACGCTTATGGGGCAGGAGCGATTAAAGCGAGCGAAATTTTCTTAC
AAGAAGGGGCTAATTATTTAGGGGTAGCGACCTTAGATGAAGCTTTAGAGTTGCGTTCTCATTTTTCTAAAACCCCCATT
TTGATCTTAGGCTATAGCCCTAATGCTAACGCTTCCATGCTGGTTGATAACGATTTGAGCGCTATGATTTTTAGCCTTGA
ACAAGCGGAAGTTTTTTCTCAAATGGCTTTAAAATCTCAAAAACGCTTAAAAGTGCACATCAAAATTGATACCGGCATGC
ACCGCTTGGGTTTAGAGCCTAATTTTAAAAGCATAGAAACCATTAAAAAAATCCGCGCTTTAAAAGGTTTGGAAATAGAG
GGGATATTTACGCATTTAAGCAACGCTGATGCTAAGATTAAAACCCATGCTAAAAACCAAATGAAAGCCTTTAACGCTTT
TTTAGAGCAGCTTTTGGATCAAAAAATAGAGTTCCAATACCGCCATGCTTATAATTCTGCCGGTATCCTTTCTTTGTGTA
ACGGGAATGAAAATCGTTTGTTAAACCTTTATCGCCCAGGCATCATGCTCTATGGTTTTTACCCCTCTAATGGAATGAAA
GAATCATGCCCAACCATCTTAAAAAATGTTATCAGTTTGAAAGCGCAAATCGTTCAAATCAGAAGCGTTAAAAAAGGCGA
ATTTATTGGCTATGGCGAGCATTTTTATACCAATGAAGAGACTTTAGTGGGTGTTTTAGCTCTAGGGTATGCAGACGGGT
TAATGCGCGCTTTAGGCAATCGCATTCAAGTAGCGATCAATAACCAATTAGCCCCCCTGATTGGCAAGGTGTGCATGGAT
CAATGTTTTGTCAAACTCAATAATATTCAAGCCAAAGAGGGCGATGAGGTCATTTTGTTTGGGGATAAAAGCGCTAAGGC
TAATGACGCGAGCGAAATCGYTGCGCTTTTAAACACCATTGCTTATGAAACCATAAGCACCCTATCCAAACGCTTGGAGC
GCGTYTATATTTAA

Upstream 100 bases:

>100_bases
TATGGCTATCCCTAATTTAATCGCTTTGATTTTATTGCATAAAGTGGTTTATTCTGAAACTCGTTGGTATTTTAGCAAGC
ATTCTAACAAGTAAAATGGC

Downstream 100 bases:

>100_bases
AATCAAACCATGCAAAATTTTTATTTTGTGTTAGAATGTTTGAAAAAATTCAGGRTTAAAATATAAAATGAAAAAAGTTT
TATTTTTGTTGGTAATAAGC

Product: alanine racemase, biosynthetic (alr)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MLKRASFVEVDTASLRHNFSAVKSIVPKDACVMAVVKANAYGAGAIKASEIFLQEGANYLGVATLDEALELRSHFSKTPI
LILGYSPNANASMLVDNDLSAMIFSLEQAEVFSQMALKSQKRLKVHIKIDTGMHRLGLEPNFKSIETIKKIRALKGLEIE
GIFTHLSNADAKIKTHAKNQMKAFNAFLEQLLDQKIEFQYRHAYNSAGILSLCNGNENRLLNLYRPGIMLYGFYPSNGMK
ESCPTILKNVISLKAQIVQIRSVKKGEFIGYGEHFYTNEETLVGVLALGYADGLMRALGNRIQVAINNQLAPLIGKVCMD
QCFVKLNNIQAKEGDEVILFGDKSAKANDASEIXALLNTIAYETISTLSKRLERVYI

Sequences:

>Translated_377_residues
MLKRASFVEVDTASLRHNFSAVKSIVPKDACVMAVVKANAYGAGAIKASEIFLQEGANYLGVATLDEALELRSHFSKTPI
LILGYSPNANASMLVDNDLSAMIFSLEQAEVFSQMALKSQKRLKVHIKIDTGMHRLGLEPNFKSIETIKKIRALKGLEIE
GIFTHLSNADAKIKTHAKNQMKAFNAFLEQLLDQKIEFQYRHAYNSAGILSLCNGNENRLLNLYRPGIMLYGFYPSNGMK
ESCPTILKNVISLKAQIVQIRSVKKGEFIGYGEHFYTNEETLVGVLALGYADGLMRALGNRIQVAINNQLAPLIGKVCMD
QCFVKLNNIQAKEGDEVILFGDKSAKANDASEIXALLNTIAYETISTLSKRLERVYI
>Mature_377_residues
MLKRASFVEVDTASLRHNFSAVKSIVPKDACVMAVVKANAYGAGAIKASEIFLQEGANYLGVATLDEALELRSHFSKTPI
LILGYSPNANASMLVDNDLSAMIFSLEQAEVFSQMALKSQKRLKVHIKIDTGMHRLGLEPNFKSIETIKKIRALKGLEIE
GIFTHLSNADAKIKTHAKNQMKAFNAFLEQLLDQKIEFQYRHAYNSAGILSLCNGNENRLLNLYRPGIMLYGFYPSNGMK
ESCPTILKNVISLKAQIVQIRSVKKGEFIGYGEHFYTNEETLVGVLALGYADGLMRALGNRIQVAINNQLAPLIGKVCMD
QCFVKLNNIQAKEGDEVILFGDKSAKANDASEIXALLNTIAYETISTLSKRLERVYI

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=385, Percent_Identity=30.9090909090909, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI1787439, Length=384, Percent_Identity=28.6458333333333, Blast_Score=132, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 41675; Mature: 41675

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKRASFVEVDTASLRHNFSAVKSIVPKDACVMAVVKANAYGAGAIKASEIFLQEGANYL
CCCCCCEEEECHHHHHHHHHHHHHHCCCCHHEEEEEECCCCCCCCCHHHHHHHHCCCCEE
GVATLDEALELRSHFSKTPILILGYSPNANASMLVDNDLSAMIFSLEQAEVFSQMALKSQ
EHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCC
KRLKVHIKIDTGMHRLGLEPNFKSIETIKKIRALKGLEIEGIFTHLSNADAKIKTHAKNQ
CEEEEEEEEECCHHHCCCCCCHHHHHHHHHHHHHCCCCEEHHHHHHCCCCCEEEHHHHHH
MKAFNAFLEQLLDQKIEFQYRHAYNSAGILSLCNGNENRLLNLYRPGIMLYGFYPSNGMK
HHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEECCCCCCEEEEECCCEEEEEEECCCCCC
ESCPTILKNVISLKAQIVQIRSVKKGEFIGYGEHFYTNEETLVGVLALGYADGLMRALGN
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEECCCHHHHHHHHHHHHHHHHHHCCC
RIQVAINNQLAPLIGKVCMDQCFVKLNNIQAKEGDEVILFGDKSAKANDASEIXALLNTI
EEEEEECCCHHHHHHHHHHHHHHHHHCCEECCCCCEEEEECCCCCCCCCHHHHHHHHHHH
AYETISTLSKRLERVYI
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLKRASFVEVDTASLRHNFSAVKSIVPKDACVMAVVKANAYGAGAIKASEIFLQEGANYL
CCCCCCEEEECHHHHHHHHHHHHHHCCCCHHEEEEEECCCCCCCCCHHHHHHHHCCCCEE
GVATLDEALELRSHFSKTPILILGYSPNANASMLVDNDLSAMIFSLEQAEVFSQMALKSQ
EHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCC
KRLKVHIKIDTGMHRLGLEPNFKSIETIKKIRALKGLEIEGIFTHLSNADAKIKTHAKNQ
CEEEEEEEEECCHHHCCCCCCHHHHHHHHHHHHHCCCCEEHHHHHHCCCCCEEEHHHHHH
MKAFNAFLEQLLDQKIEFQYRHAYNSAGILSLCNGNENRLLNLYRPGIMLYGFYPSNGMK
HHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEECCCCCCEEEEECCCEEEEEEECCCCCC
ESCPTILKNVISLKAQIVQIRSVKKGEFIGYGEHFYTNEETLVGVLALGYADGLMRALGN
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEECCCHHHHHHHHHHHHHHHHHHCCC
RIQVAINNQLAPLIGKVCMDQCFVKLNNIQAKEGDEVILFGDKSAKANDASEIXALLNTI
EEEEEECCCHHHHHHHHHHHHHHHHHCCEECCCCCEEEEECCCCCCCCCHHHHHHHHHHH
AYETISTLSKRLERVYI
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA