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Identifier: 15645558

GI number: 15645558

Start: 1002282

End: 1003634

Strand: Reverse

Name: Not Available

Synonym: HP0942

Alternate gene names: 15645558

Gene position: 1003634-1002282 (Counterclockwise)

Preceding gene: 15645559

Following gene: 15645557

Centisome position: 60.17

GC content: 43.24

Gene sequence:

>1353_bases
ATGGAAACGATTGATTCGGTGGTGCGTTTGTTATCTAATTTGGTGTGGGGGATTCCCATGCAAATTTTATTAGTAGGCAC
CGGCTTGTTTTTAACCTTTTATCTTAGGGGTTTGCAATTCAGTAAGATTTTTTATGCGATCAAAATCCTTTTTGACAAAG
AGTCCCAATCTAAGGGCGACATTTCACAATTTTCCGCTCTCATGCTCTCTTTGGGGGCGACTGTAGGCATTGGGAGTATC
GTAGGCGTAGCGACCGCTATTAGCATCGCAGGGCCAGGAGCGGTGTTTTGGATGTGGGTTACTGGGCTTGTTGGCATGGC
GACTAAGTATTCTGAGGGGATTTTAGCGGTGAAATACCGGGAAAAAGGGGCGTTTGGATACAACGGAGGGCCCATGTATT
ACATCAAAAACGGTCTTAACATGCCCAAACTCGCCATGGCGTTTGCGATTTTTACGATTATTGCAAGCATTGGCACCGGT
AACATGACGCAATCTAATGCGGTTTCTTCCATTTTAAGCGAACAAGCGAACCTGCCTAATTGGGTTTCAGGTTTATTGCT
CACTCTTTTAACCGCTTTCATTGTCATAGGGGGGATCAAATCCATTGGTAAATTCACTTCTTACTTAGCTCCTGTTATGG
TGCTTTTATATTTGATCGCTATTATTTATATTATTGTTAGCCATTTTGATTTAGCCCTTCAAGCGATCAAACTCATTTTT
GAAGAAGCCTTTAACCCTAAACCCGTTGTGGGCGGAGCGAGCGGCGCGTTGATAGCGACGATGATAAAAACGGGCGTGGC
TAGGGGGTTGTATTCTAATGAAGCGGGGTTAGGGAGCTCAGCCATTATTGCCGCGAGCGCTCAAACACGCCACCCGGTGC
GCCAAGCCTTAGTGTCCATGCTCCAAACTTTTATTGTAACCTTAATAGTGTGTTCGGCAACAGCGAGCGTGATTTTAATG
GCTCCAGAATACAACACCTTGCTCCCTAATGGGGAAAAATTAAGCGCTAATTTGCTCACTCTAAAAAGCACGGAGTATTT
TCTAGGCTCATTAGGGACGGTGGTGATTTTTACAACCATGATCTTTTTTGCCTACTCTACGATCATTGGTTGGGCTTATT
ATGGGGAAAAATGCACTGAATACGCCTTTGGTGAAAAAAAAGTGAAATATTACCGCTTGATCTTTTTAGCGAGTGTGATG
GTGGGGGCTATGGCCAAAATTGATTTTGTGTGGAATTTAGCGGATCTTTCTAACGGGCTTATGGCTATCCCTAATTTAAT
CGCTTTGATTTTATTGCATAAAGTGGTTTATTCTGAAACTCGTTGGTATTTTAGCAAGCATTCTAACAAGTAA

Upstream 100 bases:

>100_bases
GACGGAGCGAATGAAAAAAATGCCGATATTATGCTTTTTTCTGCATTTTTTAGGGATTAAGGAATTTCTTTTTTAAACCC
TAGTTTATTAAGGAGTTTTT

Downstream 100 bases:

>100_bases
AATGGCATGTTAAAAAGGGCGAGTTTTGTAGAAGTGGATACCGCTTCTTTAAGGCATAATTTTAGCGCAGTCAAAAGCAT
TGTCCCTAAAGACGCTTGTG

Product: D-alanine glycine permease

Products: Na (I) [Cytoplasm]; L-alanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
METIDSVVRLLSNLVWGIPMQILLVGTGLFLTFYLRGLQFSKIFYAIKILFDKESQSKGDISQFSALMLSLGATVGIGSI
VGVATAISIAGPGAVFWMWVTGLVGMATKYSEGILAVKYREKGAFGYNGGPMYYIKNGLNMPKLAMAFAIFTIIASIGTG
NMTQSNAVSSILSEQANLPNWVSGLLLTLLTAFIVIGGIKSIGKFTSYLAPVMVLLYLIAIIYIIVSHFDLALQAIKLIF
EEAFNPKPVVGGASGALIATMIKTGVARGLYSNEAGLGSSAIIAASAQTRHPVRQALVSMLQTFIVTLIVCSATASVILM
APEYNTLLPNGEKLSANLLTLKSTEYFLGSLGTVVIFTTMIFFAYSTIIGWAYYGEKCTEYAFGEKKVKYYRLIFLASVM
VGAMAKIDFVWNLADLSNGLMAIPNLIALILLHKVVYSETRWYFSKHSNK

Sequences:

>Translated_450_residues
METIDSVVRLLSNLVWGIPMQILLVGTGLFLTFYLRGLQFSKIFYAIKILFDKESQSKGDISQFSALMLSLGATVGIGSI
VGVATAISIAGPGAVFWMWVTGLVGMATKYSEGILAVKYREKGAFGYNGGPMYYIKNGLNMPKLAMAFAIFTIIASIGTG
NMTQSNAVSSILSEQANLPNWVSGLLLTLLTAFIVIGGIKSIGKFTSYLAPVMVLLYLIAIIYIIVSHFDLALQAIKLIF
EEAFNPKPVVGGASGALIATMIKTGVARGLYSNEAGLGSSAIIAASAQTRHPVRQALVSMLQTFIVTLIVCSATASVILM
APEYNTLLPNGEKLSANLLTLKSTEYFLGSLGTVVIFTTMIFFAYSTIIGWAYYGEKCTEYAFGEKKVKYYRLIFLASVM
VGAMAKIDFVWNLADLSNGLMAIPNLIALILLHKVVYSETRWYFSKHSNK
>Mature_450_residues
METIDSVVRLLSNLVWGIPMQILLVGTGLFLTFYLRGLQFSKIFYAIKILFDKESQSKGDISQFSALMLSLGATVGIGSI
VGVATAISIAGPGAVFWMWVTGLVGMATKYSEGILAVKYREKGAFGYNGGPMYYIKNGLNMPKLAMAFAIFTIIASIGTG
NMTQSNAVSSILSEQANLPNWVSGLLLTLLTAFIVIGGIKSIGKFTSYLAPVMVLLYLIAIIYIIVSHFDLALQAIKLIF
EEAFNPKPVVGGASGALIATMIKTGVARGLYSNEAGLGSSAIIAASAQTRHPVRQALVSMLQTFIVTLIVCSATASVILM
APEYNTLLPNGEKLSANLLTLKSTEYFLGSLGTVVIFTTMIFFAYSTIIGWAYYGEKCTEYAFGEKKVKYYRLIFLASVM
VGAMAKIDFVWNLADLSNGLMAIPNLIALILLHKVVYSETRWYFSKHSNK

Specific function: Unknown

COG id: COG1115

COG function: function code E; Na+/alanine symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:alanine (SAF) symporter family [H]

Homologues:

Organism=Escherichia coli, GI1786188, Length=443, Percent_Identity=33.6343115124154, Blast_Score=218, Evalue=5e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001463 [H]

Pfam domain/function: PF01235 Na_Ala_symp [H]

EC number: NA

Molecular weight: Translated: 48726; Mature: 48726

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METIDSVVRLLSNLVWGIPMQILLVGTGLFLTFYLRGLQFSKIFYAIKILFDKESQSKGD
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCC
ISQFSALMLSLGATVGIGSIVGVATAISIAGPGAVFWMWVTGLVGMATKYSEGILAVKYR
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEE
EKGAFGYNGGPMYYIKNGLNMPKLAMAFAIFTIIASIGTGNMTQSNAVSSILSEQANLPN
CCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCH
WVSGLLLTLLTAFIVIGGIKSIGKFTSYLAPVMVLLYLIAIIYIIVSHFDLALQAIKLIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEAFNPKPVVGGASGALIATMIKTGVARGLYSNEAGLGSSAIIAASAQTRHPVRQALVSM
HHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHH
LQTFIVTLIVCSATASVILMAPEYNTLLPNGEKLSANLLTLKSTEYFLGSLGTVVIFTTM
HHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHH
IFFAYSTIIGWAYYGEKCTEYAFGEKKVKYYRLIFLASVMVGAMAKIDFVWNLADLSNGL
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHCCCH
MAIPNLIALILLHKVVYSETRWYFSKHSNK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
METIDSVVRLLSNLVWGIPMQILLVGTGLFLTFYLRGLQFSKIFYAIKILFDKESQSKGD
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCC
ISQFSALMLSLGATVGIGSIVGVATAISIAGPGAVFWMWVTGLVGMATKYSEGILAVKYR
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEE
EKGAFGYNGGPMYYIKNGLNMPKLAMAFAIFTIIASIGTGNMTQSNAVSSILSEQANLPN
CCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCH
WVSGLLLTLLTAFIVIGGIKSIGKFTSYLAPVMVLLYLIAIIYIIVSHFDLALQAIKLIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEAFNPKPVVGGASGALIATMIKTGVARGLYSNEAGLGSSAIIAASAQTRHPVRQALVSM
HHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHH
LQTFIVTLIVCSATASVILMAPEYNTLLPNGEKLSANLLTLKSTEYFLGSLGTVVIFTTM
HHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHH
IFFAYSTIIGWAYYGEKCTEYAFGEKKVKYYRLIFLASVMVGAMAKIDFVWNLADLSNGL
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHCCCH
MAIPNLIALILLHKVVYSETRWYFSKHSNK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-alanine [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-alanine [Periplasm] = Na (I) [Cytoplasm] + L-alanine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]