| Definition | Helicobacter pylori 26695, complete genome. |
|---|---|
| Accession | NC_000915 |
| Length | 1,667,867 |
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Identifier: 15645020
GI number: 15645020
Start: 400546
End: 402957
Strand: Reverse
Name: Not Available
Synonym: HP0392
Alternate gene names: 15645020
Gene position: 402957-400546 (Counterclockwise)
Preceding gene: 15645021
Following gene: 15645019
Centisome position: 24.16
GC content: 42.99
Gene sequence:
>2412_bases ATGGATGATTTGCAAGAAATAATGGAAGACTTCTTGATTGAAGCCTTTGAAATGAACGAGCAATTGGATCAGGATTTAGT GGAATTGGAGCATAACCCTGAGGATTTGGACTTGCTCAATCGCATTTTTAGAGTCGCCCACACCATTAAAGGCTCTAGCT CGTTTTTGAATCTTAACATTCTCACGCACCTCACGCACAACATGGAAGATGTCTTGAATCGCGCCAGAAAGGGCGAAATC AAAATCACGCCTGATATTATGGATGTCGTGTTGCGCTCCATTGATTTGATGAAAACCTTGCTCGTAACGATTAGAGATAC CGGCTCTGATACTAATAACGGCAAGGAAAACGAGATTGAAGAAGCGGTCAAACAACTTCAAGCCATCACGAGTCAAAATT TAGAGAGTGCTAAAGAAAGGACTACAGAAGCCCCCCAAAAAGAAAATAAAGAAGAGACGAAAGAAGAAGCGAAAGAAGAA AATAAAGAAAACAAGGCAAAAGCCCCTACTGCAGAAAACACATCAAGCGATAACCCGCTAGCCGATGAGCCGGATTTGGA TTACGCTAACATGAGCGCTGAAGAAGTGGAAGCAGAGATTGAACGGCTGCTGAACAAACGCCAAGAAGCCGATAAAGAAC GAAGAGCTCAAAAAAAACAAGAAGCCAAACCCAAACAAGAAGTTACCCCAACAAAAGAAACCCCCAAAGCCCCTAAAACC GAAACTAAAGCTAAGGCTAAAGCCGATACTGAAGAAAATAAAGCCCCCTCTATTGGCGTGGAGCAAACCGTTAGGGTGGA TGTGCGCCGCTTGGATCACTTGATGAATTTAATCGGCGAGCTTGTGTTAGGGAAGAATCGCTTGATCAGGATTTATAGCG ATGTGGAAGAACGCTATGATGGGGAAAAGTTTTTAGAGGAATTAAACCAGGTGGTCTCTTCTATTTCAGCGGTAACGACA GACTTGCAGCTTGCGGTGATGAAAACACGGATGCAACCAGTGGGTAAGGTGTTCAATAAATTCCCTCGCATGGTAAGGGA TTTGAGCCGGGAATTAGGCAAGAGCATTGAATTGATCATTGAGGGCGAAGAAACCGAATTAGACAAATCCATTGTAGAAG AGATTGGCGATCCGCTCATTCACATTATCCGCAACTCATGCGATCATGGGATTGAGCCTTTAGAAGAAAGACGAAAGCTT AACAAGCCTGAAACCGGTAAAGTGCAATTGAGCGCGTATAATGAGGGTAACCACATTGTGATTAAAATCTCTGATGATGG CAAAGGGTTAGACCCTGTGATGCTTAAAGAAAAAGCGATTGAAAAAGGGGTGATTAGCGAAAGAGACGCTGAAGGCATGA GCGATAGGGAAGCGTTTAACCTCATTTTCAAGCCAGGCTTTTCTACCGCAAAAGTCGTTTCCAATGTCTCAGGCAGGGGT GTTGGCATGGATGTGGTGAAAACCAATATTGAAAAGCTCAATGGGATCATTGAAATTGATTCAGAAGTGGGGGTAGGCAC GACTCAAAAGCTTAAAATCCCTCTCACTTTGGCTATCATTCAAGCTTTACTCGTGGGCGTTCAAGAAGAATATTACGCTA TCCCGCTTTCTTCAGTGTTAGAAACCGTGCGCATCAGCCAGGATGAAATTTACACCGTTGATGGCAAGAGCGTGTTGCGT TTGAGAGATGAGGTGCTTTCTTTGGTGCGCCTTTCTGATATTTTTAAAGTAGATGCTATTTTGGAATCCAACTCAGATGT GTATGTGGTTATCATTGGCTTGGCTGATCAAAAAATTGGCGTGATCGTGGATTATTTAATCGGTCAAGAAGAAGTGGTCA TTAAATCTTTAGGTTACTATCTTAAAAACACTAGAGGCATTGCTGGTGCTACGGTGAGAGGCGATGGGAAAATCACCCTT ATTGTAGATGTGGGGGCGATGATGGATATGGCAAAAAGCATCAAGGTCAATATCACTACCTTAATGAACGAATCCGAAAA CACGAAGAGCAAAAATTCCCCTAGCGATTATATTGTCTTAGCGATTGATGACAGCAGCACGGATAGAGCGATTATCCGCA AATGTTTAAAACCATTAGGCATCACGCTTTTAGAGGCGACTAACGGGTTAGAGGGCTTAGAAATGCTTAAAAATGGCGAT AAGATTCCGGACGCTATTTTAGTGGATATTGAAATGCCTAAAATGGACGGCTACACTTTCGCTTCTGAAGTGCGTAAATA CAATAAATTCAAAAACCTGCCTTTGATCGCAGTAACCAGTCGGGTAACTAAAACCGATAGGATGCGTGGCGTTGAATCCG GCATGACTGAATACATCACCAAACCTTATAGCGGTGAATATTTAACCACCGTAGTGAAGCGCAGCATTAAATTAGAAGGA GACCAATCGTGA
Upstream 100 bases:
>100_bases AATTCACCGAAGAAATTTCTAAGATTTTAGACAAGAATGCGTAATTCTTTTTATAAAATTGTAAAATACTCTTATCTCAA ACGCTAAAAAGGGGTTTTAA
Downstream 100 bases:
>100_bases GCAACCAATTAAAAGATTTATTTGAAAGACAAAAAGAAGCTAGTGCAGGCTCTAAACAAGAAGACAATGAAGAGGTTTTG CAATTCATTGGCTTTATTAT
Product: histidine kinase (cheA)
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 803; Mature: 803
Protein sequence:
>803_residues MDDLQEIMEDFLIEAFEMNEQLDQDLVELEHNPEDLDLLNRIFRVAHTIKGSSSFLNLNILTHLTHNMEDVLNRARKGEI KITPDIMDVVLRSIDLMKTLLVTIRDTGSDTNNGKENEIEEAVKQLQAITSQNLESAKERTTEAPQKENKEETKEEAKEE NKENKAKAPTAENTSSDNPLADEPDLDYANMSAEEVEAEIERLLNKRQEADKERRAQKKQEAKPKQEVTPTKETPKAPKT ETKAKAKADTEENKAPSIGVEQTVRVDVRRLDHLMNLIGELVLGKNRLIRIYSDVEERYDGEKFLEELNQVVSSISAVTT DLQLAVMKTRMQPVGKVFNKFPRMVRDLSRELGKSIELIIEGEETELDKSIVEEIGDPLIHIIRNSCDHGIEPLEERRKL NKPETGKVQLSAYNEGNHIVIKISDDGKGLDPVMLKEKAIEKGVISERDAEGMSDREAFNLIFKPGFSTAKVVSNVSGRG VGMDVVKTNIEKLNGIIEIDSEVGVGTTQKLKIPLTLAIIQALLVGVQEEYYAIPLSSVLETVRISQDEIYTVDGKSVLR LRDEVLSLVRLSDIFKVDAILESNSDVYVVIIGLADQKIGVIVDYLIGQEEVVIKSLGYYLKNTRGIAGATVRGDGKITL IVDVGAMMDMAKSIKVNITTLMNESENTKSKNSPSDYIVLAIDDSSTDRAIIRKCLKPLGITLLEATNGLEGLEMLKNGD KIPDAILVDIEMPKMDGYTFASEVRKYNKFKNLPLIAVTSRVTKTDRMRGVESGMTEYITKPYSGEYLTTVVKRSIKLEG DQS
Sequences:
>Translated_803_residues MDDLQEIMEDFLIEAFEMNEQLDQDLVELEHNPEDLDLLNRIFRVAHTIKGSSSFLNLNILTHLTHNMEDVLNRARKGEI KITPDIMDVVLRSIDLMKTLLVTIRDTGSDTNNGKENEIEEAVKQLQAITSQNLESAKERTTEAPQKENKEETKEEAKEE NKENKAKAPTAENTSSDNPLADEPDLDYANMSAEEVEAEIERLLNKRQEADKERRAQKKQEAKPKQEVTPTKETPKAPKT ETKAKAKADTEENKAPSIGVEQTVRVDVRRLDHLMNLIGELVLGKNRLIRIYSDVEERYDGEKFLEELNQVVSSISAVTT DLQLAVMKTRMQPVGKVFNKFPRMVRDLSRELGKSIELIIEGEETELDKSIVEEIGDPLIHIIRNSCDHGIEPLEERRKL NKPETGKVQLSAYNEGNHIVIKISDDGKGLDPVMLKEKAIEKGVISERDAEGMSDREAFNLIFKPGFSTAKVVSNVSGRG VGMDVVKTNIEKLNGIIEIDSEVGVGTTQKLKIPLTLAIIQALLVGVQEEYYAIPLSSVLETVRISQDEIYTVDGKSVLR LRDEVLSLVRLSDIFKVDAILESNSDVYVVIIGLADQKIGVIVDYLIGQEEVVIKSLGYYLKNTRGIAGATVRGDGKITL IVDVGAMMDMAKSIKVNITTLMNESENTKSKNSPSDYIVLAIDDSSTDRAIIRKCLKPLGITLLEATNGLEGLEMLKNGD KIPDAILVDIEMPKMDGYTFASEVRKYNKFKNLPLIAVTSRVTKTDRMRGVESGMTEYITKPYSGEYLTTVVKRSIKLEG DQS >Mature_803_residues MDDLQEIMEDFLIEAFEMNEQLDQDLVELEHNPEDLDLLNRIFRVAHTIKGSSSFLNLNILTHLTHNMEDVLNRARKGEI KITPDIMDVVLRSIDLMKTLLVTIRDTGSDTNNGKENEIEEAVKQLQAITSQNLESAKERTTEAPQKENKEETKEEAKEE NKENKAKAPTAENTSSDNPLADEPDLDYANMSAEEVEAEIERLLNKRQEADKERRAQKKQEAKPKQEVTPTKETPKAPKT ETKAKAKADTEENKAPSIGVEQTVRVDVRRLDHLMNLIGELVLGKNRLIRIYSDVEERYDGEKFLEELNQVVSSISAVTT DLQLAVMKTRMQPVGKVFNKFPRMVRDLSRELGKSIELIIEGEETELDKSIVEEIGDPLIHIIRNSCDHGIEPLEERRKL NKPETGKVQLSAYNEGNHIVIKISDDGKGLDPVMLKEKAIEKGVISERDAEGMSDREAFNLIFKPGFSTAKVVSNVSGRG VGMDVVKTNIEKLNGIIEIDSEVGVGTTQKLKIPLTLAIIQALLVGVQEEYYAIPLSSVLETVRISQDEIYTVDGKSVLR LRDEVLSLVRLSDIFKVDAILESNSDVYVVIIGLADQKIGVIVDYLIGQEEVVIKSLGYYLKNTRGIAGATVRGDGKITL IVDVGAMMDMAKSIKVNITTLMNESENTKSKNSPSDYIVLAIDDSSTDRAIIRKCLKPLGITLLEATNGLEGLEMLKNGD KIPDAILVDIEMPKMDGYTFASEVRKYNKFKNLPLIAVTSRVTKTDRMRGVESGMTEYITKPYSGEYLTTVVKRSIKLEG DQS
Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]
COG id: COG0643
COG function: function code NT; Chemotaxis protein histidine kinase and related kinases
Gene ontology:
Cell location: Membrane (Potential). Note=It is not known whether CheA is actually membrane bound although CheA has two regions at the C-terminal end with the potential to be transmembrane regions [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 HPt domain [H]
Homologues:
Organism=Escherichia coli, GI1788197, Length=654, Percent_Identity=34.4036697247706, Blast_Score=350, Evalue=2e-97, Organism=Escherichia coli, GI1790299, Length=119, Percent_Identity=31.0924369747899, Blast_Score=66, Evalue=1e-11, Organism=Escherichia coli, GI1788394, Length=87, Percent_Identity=34.4827586206897, Blast_Score=64, Evalue=5e-11, Organism=Escherichia coli, GI145693157, Length=127, Percent_Identity=29.1338582677165, Blast_Score=63, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003594 - InterPro: IPR002545 - InterPro: IPR004358 - InterPro: IPR008207 - InterPro: IPR004105 - InterPro: IPR005467 - InterPro: IPR009082 - InterPro: IPR010808 [H]
Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]
EC number: =2.7.13.3 [H]
Molecular weight: Translated: 89761; Mature: 89761
Theoretical pI: Translated: 4.70; Mature: 4.70
Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN ; PS00217 SUGAR_TRANSPORT_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 2.9 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 2.9 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDDLQEIMEDFLIEAFEMNEQLDQDLVELEHNPEDLDLLNRIFRVAHTIKGSSSFLNLNI CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEHH LTHLTHNMEDVLNRARKGEIKITPDIMDVVLRSIDLMKTLLVTIRDTGSDTNNGKENEIE HHHHHCCHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH EAVKQLQAITSQNLESAKERTTEAPQKENKEETKEEAKEENKENKAKAPTAENTSSDNPL HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCCCCCC ADEPDLDYANMSAEEVEAEIERLLNKRQEADKERRAQKKQEAKPKQEVTPTKETPKAPKT CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC ETKAKAKADTEENKAPSIGVEQTVRVDVRRLDHLMNLIGELVLGKNRLIRIYSDVEERYD HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCC GEKFLEELNQVVSSISAVTTDLQLAVMKTRMQPVGKVFNKFPRMVRDLSRELGKSIELII HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE EGEETELDKSIVEEIGDPLIHIIRNSCDHGIEPLEERRKLNKPETGKVQLSAYNEGNHIV ECCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCEEEEEEECCCCEEE IKISDDGKGLDPVMLKEKAIEKGVISERDAEGMSDREAFNLIFKPGFSTAKVVSNVSGRG EEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHEEEECCCCCHHHHHHCCCCCC VGMDVVKTNIEKLNGIIEIDSEVGVGTTQKLKIPLTLAIIQALLVGVQEEYYAIPLSSVL CCHHHHHHHHHHCCCEEEECCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHEECCHHHHH ETVRISQDEIYTVDGKSVLRLRDEVLSLVRLSDIFKVDAILESNSDVYVVIIGLADQKIG HHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHH VIVDYLIGQEEVVIKSLGYYLKNTRGIAGATVRGDGKITLIVDVGAMMDMAKSIKVNITT HHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEEECHHHHHHHHHHEEEEEE LMNESENTKSKNSPSDYIVLAIDDSSTDRAIIRKCLKPLGITLLEATNGLEGLEMLKNGD EECCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCEEEEHHCCCHHHHHHHHCCC KIPDAILVDIEMPKMDGYTFASEVRKYNKFKNLPLIAVTSRVTKTDRMRGVESGMTEYIT CCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHC KPYSGEYLTTVVKRSIKLEGDQS CCCCCHHHHHHHHHHHCCCCCCC >Mature Secondary Structure MDDLQEIMEDFLIEAFEMNEQLDQDLVELEHNPEDLDLLNRIFRVAHTIKGSSSFLNLNI CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEHH LTHLTHNMEDVLNRARKGEIKITPDIMDVVLRSIDLMKTLLVTIRDTGSDTNNGKENEIE HHHHHCCHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH EAVKQLQAITSQNLESAKERTTEAPQKENKEETKEEAKEENKENKAKAPTAENTSSDNPL HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCCCCCC ADEPDLDYANMSAEEVEAEIERLLNKRQEADKERRAQKKQEAKPKQEVTPTKETPKAPKT CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC ETKAKAKADTEENKAPSIGVEQTVRVDVRRLDHLMNLIGELVLGKNRLIRIYSDVEERYD HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCC GEKFLEELNQVVSSISAVTTDLQLAVMKTRMQPVGKVFNKFPRMVRDLSRELGKSIELII HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE EGEETELDKSIVEEIGDPLIHIIRNSCDHGIEPLEERRKLNKPETGKVQLSAYNEGNHIV ECCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCEEEEEEECCCCEEE IKISDDGKGLDPVMLKEKAIEKGVISERDAEGMSDREAFNLIFKPGFSTAKVVSNVSGRG EEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHEEEECCCCCHHHHHHCCCCCC VGMDVVKTNIEKLNGIIEIDSEVGVGTTQKLKIPLTLAIIQALLVGVQEEYYAIPLSSVL CCHHHHHHHHHHCCCEEEECCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHEECCHHHHH ETVRISQDEIYTVDGKSVLRLRDEVLSLVRLSDIFKVDAILESNSDVYVVIIGLADQKIG HHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHH VIVDYLIGQEEVVIKSLGYYLKNTRGIAGATVRGDGKITLIVDVGAMMDMAKSIKVNITT HHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEEECHHHHHHHHHHEEEEEE LMNESENTKSKNSPSDYIVLAIDDSSTDRAIIRKCLKPLGITLLEATNGLEGLEMLKNGD EECCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCEEEEHHCCCHHHHHHHHCCC KIPDAILVDIEMPKMDGYTFASEVRKYNKFKNLPLIAVTSRVTKTDRMRGVESGMTEYIT CCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHC KPYSGEYLTTVVKRSIKLEGDQS CCCCCHHHHHHHHHHHCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 1938941; 9384377 [H]