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Identifier: 15645017

GI number: 15645017

Start: 398432

End: 399073

Strand: Reverse

Name: Not Available

Synonym: HP0389

Alternate gene names: 15645017

Gene position: 399073-398432 (Counterclockwise)

Preceding gene: 15645019

Following gene: 15645016

Centisome position: 23.93

GC content: 39.25

Gene sequence:

>642_bases
ATGTTTACATTACGAGAGTTGCCTTTTGCTAAAGACAGCATGGGAGATTTTTTAAGCCCTGTAGCGTTTGATTTCCACCA
TGGGAAACACCATCAAACTTATGTGAATAATTTGAACAATCTCATCAAAGGCACGGATTTTGAGAAAAGTTCTTTGTTTG
ATATTTTGACGAAGTCTAGCGGAGGCGTGTTCAATAACGCCGCTCAAATTTATAACCACGATTTTTATTGGGATTGCCTA
AGCCCCAAAGCGACTGCCCTAAGCGATGAGTTAAAAGGGGCTTTAGAAAAAGATTTTGGCTCATTGGAACAATTTAAAGA
AGACTTCATTAAGAGCGCGACCACTTTGTTTGGCTCTGGTTGGAATTGGGTAGCGTATAATTTAGACACTCAAAAAATTG
AAATCATTCAAACGAGCAACGCTCAAACCCCAGTTACGGATAAAAAAGTGCCGCTTTTAGTGGTGGATGTGTGGGAGCAT
GCTTATTACATTGACCATAAAAACGCGCGCCCTGTGTATTTGGAAAAGTTCTATGAGCATATCAATTGGCATTTTGTTTC
TCAATGCTATGAATGGGCGAAAAAAGAAGGCTTAGGATCAGTGGATTACTACATCAATGAGTTGGTGCATAAAAAAGCTT
AA

Upstream 100 bases:

>100_bases
AATCCACAAAATTTGCATAAAGATCCATTTTTAAGAAAAGATTTACCAAAAAGTATTAAAAAATGATTACAATAAGGCTA
TCTGATCACAAGGAGAAAAC

Downstream 100 bases:

>100_bases
GCGTTATTTTGCATAGAGTGGTTTAAAGGTTTTTAAACCACGCTTCTTTGTTGAATGAAAGACACTCTGTTTAATGAATC
CCTAAACAAACGCTTTTGTT

Product: iron-dependent superoxide dismutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MFTLRELPFAKDSMGDFLSPVAFDFHHGKHHQTYVNNLNNLIKGTDFEKSSLFDILTKSSGGVFNNAAQIYNHDFYWDCL
SPKATALSDELKGALEKDFGSLEQFKEDFIKSATTLFGSGWNWVAYNLDTQKIEIIQTSNAQTPVTDKKVPLLVVDVWEH
AYYIDHKNARPVYLEKFYEHINWHFVSQCYEWAKKEGLGSVDYYINELVHKKA

Sequences:

>Translated_213_residues
MFTLRELPFAKDSMGDFLSPVAFDFHHGKHHQTYVNNLNNLIKGTDFEKSSLFDILTKSSGGVFNNAAQIYNHDFYWDCL
SPKATALSDELKGALEKDFGSLEQFKEDFIKSATTLFGSGWNWVAYNLDTQKIEIIQTSNAQTPVTDKKVPLLVVDVWEH
AYYIDHKNARPVYLEKFYEHINWHFVSQCYEWAKKEGLGSVDYYINELVHKKA
>Mature_213_residues
MFTLRELPFAKDSMGDFLSPVAFDFHHGKHHQTYVNNLNNLIKGTDFEKSSLFDILTKSSGGVFNNAAQIYNHDFYWDCL
SPKATALSDELKGALEKDFGSLEQFKEDFIKSATTLFGSGWNWVAYNLDTQKIEIIQTSNAQTPVTDKKVPLLVVDVWEH
AYYIDHKNARPVYLEKFYEHINWHFVSQCYEWAKKEGLGSVDYYINELVHKKA

Specific function: Destroys radicals which are normally produced within the cells and which are toxic to biological systems [H]

COG id: COG0605

COG function: function code P; Superoxide dismutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron/manganese superoxide dismutase family [H]

Homologues:

Organism=Homo sapiens, GI67782307, Length=204, Percent_Identity=35.7843137254902, Blast_Score=123, Evalue=1e-28,
Organism=Homo sapiens, GI67782305, Length=204, Percent_Identity=35.7843137254902, Blast_Score=123, Evalue=1e-28,
Organism=Homo sapiens, GI67782309, Length=195, Percent_Identity=31.2820512820513, Blast_Score=102, Evalue=3e-22,
Organism=Escherichia coli, GI1787946, Length=188, Percent_Identity=53.7234042553192, Blast_Score=213, Evalue=1e-56,
Organism=Escherichia coli, GI1790342, Length=196, Percent_Identity=36.2244897959184, Blast_Score=135, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17569479, Length=195, Percent_Identity=34.3589743589744, Blast_Score=114, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17506561, Length=197, Percent_Identity=34.010152284264, Blast_Score=113, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6321796, Length=215, Percent_Identity=29.7674418604651, Blast_Score=92, Evalue=5e-20,
Organism=Drosophila melanogaster, GI17136812, Length=199, Percent_Identity=36.6834170854271, Blast_Score=132, Evalue=2e-31,

Paralogues:

None

Copy number: 2020 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 900 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001189
- InterPro:   IPR019833
- InterPro:   IPR019832
- InterPro:   IPR019831 [H]

Pfam domain/function: PF02777 Sod_Fe_C; PF00081 Sod_Fe_N [H]

EC number: =1.15.1.1 [H]

Molecular weight: Translated: 24618; Mature: 24618

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00088 SOD_MN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTLRELPFAKDSMGDFLSPVAFDFHHGKHHQTYVNNLNNLIKGTDFEKSSLFDILTKSS
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
GGVFNNAAQIYNHDFYWDCLSPKATALSDELKGALEKDFGSLEQFKEDFIKSATTLFGSG
CCCCCCHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
WNWVAYNLDTQKIEIIQTSNAQTPVTDKKVPLLVVDVWEHAYYIDHKNARPVYLEKFYEH
CCEEEEECCCCEEEEEECCCCCCCCCCCCCCEEEEEECHHEEEEECCCCCCHHHHHHHHH
INWHFVSQCYEWAKKEGLGSVDYYINELVHKKA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MFTLRELPFAKDSMGDFLSPVAFDFHHGKHHQTYVNNLNNLIKGTDFEKSSLFDILTKSS
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
GGVFNNAAQIYNHDFYWDCLSPKATALSDELKGALEKDFGSLEQFKEDFIKSATTLFGSG
CCCCCCHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
WNWVAYNLDTQKIEIIQTSNAQTPVTDKKVPLLVVDVWEHAYYIDHKNARPVYLEKFYEH
CCEEEEECCCCEEEEEECCCCCCCCCCCCCCEEEEEECHHEEEEECCCCCCHHHHHHHHH
INWHFVSQCYEWAKKEGLGSVDYYINELVHKKA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]