Definition Helicobacter pylori 26695, complete genome.
Accession NC_000915
Length 1,667,867

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Identifier: 15644985

GI number: 15644985

Start: 367133

End: 367885

Strand: Reverse

Name: Not Available

Synonym: HP0357

Alternate gene names: 15644985

Gene position: 367885-367133 (Counterclockwise)

Preceding gene: 15644986

Following gene: 15644977

Centisome position: 22.06

GC content: 43.29

Gene sequence:

>753_bases
ATGGCGCACATTTTAGTTAGCGGGGCGACTTCAGGGTTTGGATTAGAAATCGCTAAAGCGTTTTTACAAAAAAACCATGT
GGTTTTTGGCACAGGGAGGCGAAAAGAGAATTTACAAAAATTGCAACTCGCTTACCCTAAGCATTTCATTCCCTTGTGTT
TTGATCTTCAAAACAAGCTTGAAACTAAGCGAGCGTTAGAGGCTATTTTTTCCATGACGGATCGCATTGACGCTCTGATC
AATAACGCCGGCTTAGCACTAGGCTTGAACAAGGCTTATGAATGCGAGTTAGACGACTGGGAAATCATGATAGATACGAA
TATCAAGGGGTTGTTGCATCTCACCCGCTTGATCTTGCCCTCTATGATAGAGCATGACCAAGGGACTATCATCAATCTTG
GTTCTATCGCTGGCACTTACGCCTATCCTGGAGGGAATGTCTATGGAGCGAGCAAGGCGTTTGTGAAACAATTTTCTTTA
AATTTGCGAGCGGATTTGGCTGGCACTAACATTAGAGTGAGTAATGTTGAACCCGGTTTGTGCGGCGAAACCGAATTCAG
CATGGTGCGTTTTAAAGGCGATAAAATCAAAGCCCAATCCGTCTATGAAAACACCATCTACCTCAAACCACAAGATATTG
CTAACATCGTGCTATGGATTTATGAACAACCCTTGCATGTCAATATCAACCGCATAGAAATCATGCCTATAAGCCAAACT
TTCGCTCCCCTACCCACCCATAAAAACCCTTAA

Upstream 100 bases:

>100_bases
CCCTTAAAAAAGGTTTAGATCATTTGCTTAAAGATGATAAGCTCAAAGAAAAGCTTGAAAAAGGGCTTAAGGGGCTTTTT
TAAAATTTTAAAGGATAGAA

Downstream 100 bases:

>100_bases
GGGGTTTTAAAATAAATTTAAACTTTAACAACTCTTTAATTTTCAAAAAATAGGGGATTTTGGTTATTTTATTTTAAAAC
TCTTCATTATATCTAAATTT

Product: short chain alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MAHILVSGATSGFGLEIAKAFLQKNHVVFGTGRRKENLQKLQLAYPKHFIPLCFDLQNKLETKRALEAIFSMTDRIDALI
NNAGLALGLNKAYECELDDWEIMIDTNIKGLLHLTRLILPSMIEHDQGTIINLGSIAGTYAYPGGNVYGASKAFVKQFSL
NLRADLAGTNIRVSNVEPGLCGETEFSMVRFKGDKIKAQSVYENTIYLKPQDIANIVLWIYEQPLHVNINRIEIMPISQT
FAPLPTHKNP

Sequences:

>Translated_250_residues
MAHILVSGATSGFGLEIAKAFLQKNHVVFGTGRRKENLQKLQLAYPKHFIPLCFDLQNKLETKRALEAIFSMTDRIDALI
NNAGLALGLNKAYECELDDWEIMIDTNIKGLLHLTRLILPSMIEHDQGTIINLGSIAGTYAYPGGNVYGASKAFVKQFSL
NLRADLAGTNIRVSNVEPGLCGETEFSMVRFKGDKIKAQSVYENTIYLKPQDIANIVLWIYEQPLHVNINRIEIMPISQT
FAPLPTHKNP
>Mature_249_residues
AHILVSGATSGFGLEIAKAFLQKNHVVFGTGRRKENLQKLQLAYPKHFIPLCFDLQNKLETKRALEAIFSMTDRIDALIN
NAGLALGLNKAYECELDDWEIMIDTNIKGLLHLTRLILPSMIEHDQGTIINLGSIAGTYAYPGGNVYGASKAFVKQFSLN
LRADLAGTNIRVSNVEPGLCGETEFSMVRFKGDKIKAQSVYENTIYLKPQDIANIVLWIYEQPLHVNINRIEIMPISQTF
APLPTHKNP

Specific function: Unknown

COG id: COG4221

COG function: function code R; Short-chain alcohol dehydrogenase of unknown specificity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI109715829, Length=246, Percent_Identity=33.3333333333333, Blast_Score=119, Evalue=2e-27,
Organism=Homo sapiens, GI7706318, Length=265, Percent_Identity=29.0566037735849, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI20149619, Length=188, Percent_Identity=30.3191489361702, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI40548397, Length=180, Percent_Identity=29.4444444444444, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI214010158, Length=180, Percent_Identity=29.4444444444444, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI214010156, Length=180, Percent_Identity=29.4444444444444, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI22758144, Length=180, Percent_Identity=29.4444444444444, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI32483357, Length=226, Percent_Identity=26.5486725663717, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI22507405, Length=179, Percent_Identity=29.0502793296089, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI4758504, Length=234, Percent_Identity=26.0683760683761, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI7657478, Length=191, Percent_Identity=29.8429319371728, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787820, Length=245, Percent_Identity=50.6122448979592, Blast_Score=271, Evalue=3e-74,
Organism=Escherichia coli, GI1787335, Length=234, Percent_Identity=27.7777777777778, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1786812, Length=243, Percent_Identity=25.5144032921811, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786701, Length=179, Percent_Identity=28.4916201117318, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI87082100, Length=178, Percent_Identity=29.2134831460674, Blast_Score=76, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=187, Percent_Identity=29.4117647058824, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71994604, Length=186, Percent_Identity=29.5698924731183, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=241, Percent_Identity=25.3112033195021, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=243, Percent_Identity=26.3374485596708, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=241, Percent_Identity=24.0663900414938, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=185, Percent_Identity=28.6486486486486, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=221, Percent_Identity=24.8868778280543, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=237, Percent_Identity=26.5822784810127, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17561402, Length=193, Percent_Identity=25.9067357512953, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=246, Percent_Identity=23.9837398373984, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=245, Percent_Identity=33.8775510204082, Blast_Score=136, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6322227, Length=185, Percent_Identity=25.9459459459459, Blast_Score=78, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322226, Length=180, Percent_Identity=26.1111111111111, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322067, Length=179, Percent_Identity=27.9329608938547, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21358495, Length=225, Percent_Identity=29.7777777777778, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24643142, Length=175, Percent_Identity=31.4285714285714, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI116007236, Length=251, Percent_Identity=25.0996015936255, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI28571526, Length=181, Percent_Identity=30.939226519337, Blast_Score=87, Evalue=7e-18,
Organism=Drosophila melanogaster, GI23397609, Length=182, Percent_Identity=30.7692307692308, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24644339, Length=181, Percent_Identity=29.2817679558011, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21357041, Length=181, Percent_Identity=29.2817679558011, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI281364494, Length=250, Percent_Identity=25.2, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24641232, Length=254, Percent_Identity=29.1338582677165, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28571387, Length=250, Percent_Identity=26.8, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641388, Length=250, Percent_Identity=27.6, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24663911, Length=253, Percent_Identity=25.6916996047431, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI28574402, Length=183, Percent_Identity=30.0546448087432, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24584744, Length=183, Percent_Identity=30.0546448087432, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17737361, Length=234, Percent_Identity=26.9230769230769, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI116007234, Length=251, Percent_Identity=25.8964143426295, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24640442, Length=119, Percent_Identity=33.6134453781513, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27885; Mature: 27754

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MAHILVSGATSGFGLEIAKAFLQKNHVVFGTGRRKENLQKLQLAYPKHFIPLCFDLQNKL
CCEEEEECCCCCCCHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHH
ETKRALEAIFSMTDRIDALINNAGLALGLNKAYECELDDWEIMIDTNIKGLLHLTRLILP
HHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCCEEEEEECCCHHHHHHHHHHHH
SMIEHDQGTIINLGSIAGTYAYPGGNVYGASKAFVKQFSLNLRADLAGTNIRVSNVEPGL
HHHCCCCCCEEEECCCCCEEECCCCCEECCHHHHHHHHCCCEEEEECCCEEEEECCCCCC
CGETEFSMVRFKGDKIKAQSVYENTIYLKPQDIANIVLWIYEQPLHVNINRIEIMPISQT
CCCCCEEEEEEECCEEEECEEECCEEEECCHHHHHEEEEEECCCEEEEEEEEEEEECHHC
FAPLPTHKNP
CCCCCCCCCC
>Mature Secondary Structure 
AHILVSGATSGFGLEIAKAFLQKNHVVFGTGRRKENLQKLQLAYPKHFIPLCFDLQNKL
CEEEEECCCCCCCHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHH
ETKRALEAIFSMTDRIDALINNAGLALGLNKAYECELDDWEIMIDTNIKGLLHLTRLILP
HHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCCEEEEEECCCHHHHHHHHHHHH
SMIEHDQGTIINLGSIAGTYAYPGGNVYGASKAFVKQFSLNLRADLAGTNIRVSNVEPGL
HHHCCCCCCEEEECCCCCEEECCCCCEECCHHHHHHHHCCCEEEEECCCEEEEECCCCCC
CGETEFSMVRFKGDKIKAQSVYENTIYLKPQDIANIVLWIYEQPLHVNINRIEIMPISQT
CCCCCEEEEEEECCEEEECEEECCEEEECCHHHHHEEEEEECCCEEEEEEEEEEEECHHC
FAPLPTHKNP
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]