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Identifier: 15644741

GI number: 15644741

Start: 118823

End: 119653

Strand: Reverse

Name: Not Available

Synonym: HP0111

Alternate gene names: 15644741

Gene position: 119653-118823 (Counterclockwise)

Preceding gene: 15644744

Following gene: 15644740

Centisome position: 7.17

GC content: 38.51

Gene sequence:

>831_bases
ATGGTGATTGACGAGATTTTTCAAATAATGATGTTAAGAAGAATTAAAGTAGGTTCTAATTTGAATAAAAAAGAGAGTTT
GTTAGATGCGTTTGTTAAAACCTATCTGCAGATTTTAGAACCCATTAGTTCTAAACGCTTAAAAGAGTTGGCGGACTTGA
AAATATCTTGCGCGACGATCAGGAATTATTTTCAAATCCTTTCTAAAGAGGGCATGCTTTATCAAGCCCATTCTAGTGGC
GCTAGATTGCCCACTTTTAAGGCGTTTGAAAACTATTGGCAAAAGTCGTTGCGCTTTGAAACTTTAAAGGTGAATGAAAA
ACGCCTAAAAAGCGCGAGTGAAAATTTTGGGCTTTTCACGCTGTTAAAAAAACCCAGTTTGGAGCGTTTAGAAAGAGTCA
TTGAGTGCGAAAAACGCTTTTTGATTTTGGACTTTTTGGCGTTTTCTTGCGCACTGGGTTACAGCGTTAAAATGGAAAAG
TTTTTATTAGAGCTTGTGGGCAGAAGCGTTAAAGAAGTGCGCTCAATCGCTGCTTCTTTCAATGCGTTGAGTTTGGCCAG
GCAATTAGAGCGTTTGGAGTATTCCAACACACAAATCACACGCTTTAATCTGATGGGGTTAAAAACGCTTTTAAACAGCC
CTTTATTTTTTGACATTTTAGGGGGTAAGGTTTTAGAGCGTTTGAGTAAGGGTTTGCATTTTATAGAGCCTGATTGCATG
CTAGTAACACGCCCTGTAGAATTTCAAAACAAGCGGATGCAACTGCTTTGCGTGGGGAAACTAGAATGCGATTATGAAGG
GTTTTTTCAAACGATTTCTGAGGAGGAATAA

Upstream 100 bases:

>100_bases
TAAACTTTAAAGAAAAATCGGGTAATTTTTATCACTTTTTTAAAACAAGTGATAGATTATTAACTTTTTATGCTATAATG
CGAGGGTTCTTTCATCAAGA

Downstream 100 bases:

>100_bases
TGAAAGATGAACACAACCAAGAACACGATCATTTAAGCCAAAAAGAGCCAGAGTTTTGCGAAAAGGCTTGCAAAGAACAA
CAATATGAAGAAAAGCAAGA

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MVIDEIFQIMMLRRIKVGSNLNKKESLLDAFVKTYLQILEPISSKRLKELADLKISCATIRNYFQILSKEGMLYQAHSSG
ARLPTFKAFENYWQKSLRFETLKVNEKRLKSASENFGLFTLLKKPSLERLERVIECEKRFLILDFLAFSCALGYSVKMEK
FLLELVGRSVKEVRSIAASFNALSLARQLERLEYSNTQITRFNLMGLKTLLNSPLFFDILGGKVLERLSKGLHFIEPDCM
LVTRPVEFQNKRMQLLCVGKLECDYEGFFQTISEEE

Sequences:

>Translated_276_residues
MVIDEIFQIMMLRRIKVGSNLNKKESLLDAFVKTYLQILEPISSKRLKELADLKISCATIRNYFQILSKEGMLYQAHSSG
ARLPTFKAFENYWQKSLRFETLKVNEKRLKSASENFGLFTLLKKPSLERLERVIECEKRFLILDFLAFSCALGYSVKMEK
FLLELVGRSVKEVRSIAASFNALSLARQLERLEYSNTQITRFNLMGLKTLLNSPLFFDILGGKVLERLSKGLHFIEPDCM
LVTRPVEFQNKRMQLLCVGKLECDYEGFFQTISEEE
>Mature_276_residues
MVIDEIFQIMMLRRIKVGSNLNKKESLLDAFVKTYLQILEPISSKRLKELADLKISCATIRNYFQILSKEGMLYQAHSSG
ARLPTFKAFENYWQKSLRFETLKVNEKRLKSASENFGLFTLLKKPSLERLERVIECEKRFLILDFLAFSCALGYSVKMEK
FLLELVGRSVKEVRSIAASFNALSLARQLERLEYSNTQITRFNLMGLKTLLNSPLFFDILGGKVLERLSKGLHFIEPDCM
LVTRPVEFQNKRMQLLCVGKLECDYEGFFQTISEEE

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002571
- InterPro:   IPR011991 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 32016; Mature: 32016

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIDEIFQIMMLRRIKVGSNLNKKESLLDAFVKTYLQILEPISSKRLKELADLKISCATI
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNYFQILSKEGMLYQAHSSGARLPTFKAFENYWQKSLRFETLKVNEKRLKSASENFGLFT
HHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHEECCHHHHHHCCCCCCEEE
LLKKPSLERLERVIECEKRFLILDFLAFSCALGYSVKMEKFLLELVGRSVKEVRSIAASF
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NALSLARQLERLEYSNTQITRFNLMGLKTLLNSPLFFDILGGKVLERLSKGLHFIEPDCM
HHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEECCCCE
LVTRPVEFQNKRMQLLCVGKLECDYEGFFQTISEEE
EEECCHHHCCCCEEEEEEECCCCCHHHHHHHHCCCC
>Mature Secondary Structure
MVIDEIFQIMMLRRIKVGSNLNKKESLLDAFVKTYLQILEPISSKRLKELADLKISCATI
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNYFQILSKEGMLYQAHSSGARLPTFKAFENYWQKSLRFETLKVNEKRLKSASENFGLFT
HHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHEECCHHHHHHCCCCCCEEE
LLKKPSLERLERVIECEKRFLILDFLAFSCALGYSVKMEKFLLELVGRSVKEVRSIAASF
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NALSLARQLERLEYSNTQITRFNLMGLKTLLNSPLFFDILGGKVLERLSKGLHFIEPDCM
HHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEECCCCE
LVTRPVEFQNKRMQLLCVGKLECDYEGFFQTISEEE
EEECCHHHCCCCEEEEEEECCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]