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Identifier: 15644662

GI number: 15644662

Start: 29411

End: 30067

Strand: Reverse

Name: Not Available

Synonym: HP0029

Alternate gene names: 15644662

Gene position: 30067-29411 (Counterclockwise)

Preceding gene: 15644663

Following gene: 15644659

Centisome position: 1.8

GC content: 40.03

Gene sequence:

>657_bases
ATGCTCTTTATCAGCGCAACTAACACGAATGCCGGAAAAACCACATGCGCTAGGCTATTAGCCCAGTATTGCAACGCTTG
TGGCGTTAAAACTATCTTGTTAAAACCCATTGAAACGGGCGTTAATGACGCCATTAACCACTCTAGCGATGCGCATTTGT
TCTTGCAAGATAACCGCCTTTTAGATCGCTCTTTAACCTTAAAAGACATTTCATTCTATCGTTATCATAAAGTTTCAGCC
CCCCTCATCGCCCAACAAGAAGAAGATCCAAACGCCCCCATTGACACGGACAATTTGACCCAACGTCTCCACAATTTCAC
CAAAACTTACGATTTAGTCATCGTTGAAGGGGCTGGGGGGCTATGCGTGCCTATCACTTTAGAAGAAAACATGTTGGATT
TTGCCCTGAAATTAAAAGCCAAAATGCTTTTGATTAGCCATGACAATTTGGGCTTGATTAATGATTGTTTGCTGAATGAT
TTTTTATTGAAATCCCACCAACTAGACTATAAAATCGCTATCAATTTAAAAGGAAACAACACCGCTTTTCACAGCATCAG
CTTGCCCTATATTGAGCTTTTTAATACACGCTCCAATAACCCCATTGTGATTTTCCAACAAAGCCTAAAAGTTTTAATGA
GCTTTGCTCTTAAATAA

Upstream 100 bases:

>100_bases
AGTCCCAAGAGAAGCACTTAAAAATGTGAAGTTGCCACAAATCAAAAATGTATTGACTTCTCAAATCTTTGATGGCGCTT
ACCACTTTAAAAGTTAAACC

Downstream 100 bases:

>100_bases
AGTGCAAACAGAACGCGCGCTGATAAAAAAGCCCATTAACAGCAAAGCGTATAAAATCCAGCTAAAAATGGGCTTTGAAA
TGTCAGTGCTCTCTTTTAAG

Product: dethiobiotin synthetase (bioD)

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MLFISATNTNAGKTTCARLLAQYCNACGVKTILLKPIETGVNDAINHSSDAHLFLQDNRLLDRSLTLKDISFYRYHKVSA
PLIAQQEEDPNAPIDTDNLTQRLHNFTKTYDLVIVEGAGGLCVPITLEENMLDFALKLKAKMLLISHDNLGLINDCLLND
FLLKSHQLDYKIAINLKGNNTAFHSISLPYIELFNTRSNNPIVIFQQSLKVLMSFALK

Sequences:

>Translated_218_residues
MLFISATNTNAGKTTCARLLAQYCNACGVKTILLKPIETGVNDAINHSSDAHLFLQDNRLLDRSLTLKDISFYRYHKVSA
PLIAQQEEDPNAPIDTDNLTQRLHNFTKTYDLVIVEGAGGLCVPITLEENMLDFALKLKAKMLLISHDNLGLINDCLLND
FLLKSHQLDYKIAINLKGNNTAFHSISLPYIELFNTRSNNPIVIFQQSLKVLMSFALK
>Mature_218_residues
MLFISATNTNAGKTTCARLLAQYCNACGVKTILLKPIETGVNDAINHSSDAHLFLQDNRLLDRSLTLKDISFYRYHKVSA
PLIAQQEEDPNAPIDTDNLTQRLHNFTKTYDLVIVEGAGGLCVPITLEENMLDFALKLKAKMLLISHDNLGLINDCLLND
FLLKSHQLDYKIAINLKGNNTAFHSISLPYIELFNTRSNNPIVIFQQSLKVLMSFALK

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 24408; Mature: 24408

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFISATNTNAGKTTCARLLAQYCNACGVKTILLKPIETGVNDAINHSSDAHLFLQDNRL
CEEEEECCCCCCHHHHHHHHHHHHHHCCEEEEEEEHHHCCCCHHHCCCCCCEEEEECCCE
LDRSLTLKDISFYRYHKVSAPLIAQQEEDPNAPIDTDNLTQRLHNFTKTYDLVIVEGAGG
ECCCCCHHHHHEEEEEECCCCEEECCCCCCCCCCCHHHHHHHHHHHHCEEEEEEEECCCC
LCVPITLEENMLDFALKLKAKMLLISHDNLGLINDCLLNDFLLKSHQLDYKIAINLKGNN
EEEEEEECCCHHHHHHHEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCC
TAFHSISLPYIELFNTRSNNPIVIFQQSLKVLMSFALK
EEEEEECCCEEEEEECCCCCCEEEEHHHHHHHHHHHCC
>Mature Secondary Structure
MLFISATNTNAGKTTCARLLAQYCNACGVKTILLKPIETGVNDAINHSSDAHLFLQDNRL
CEEEEECCCCCCHHHHHHHHHHHHHHCCEEEEEEEHHHCCCCHHHCCCCCCEEEEECCCE
LDRSLTLKDISFYRYHKVSAPLIAQQEEDPNAPIDTDNLTQRLHNFTKTYDLVIVEGAGG
ECCCCCHHHHHEEEEEECCCCEEECCCCCCCCCCCHHHHHHHHHHHHCEEEEEEEECCCC
LCVPITLEENMLDFALKLKAKMLLISHDNLGLINDCLLNDFLLKSHQLDYKIAINLKGNN
EEEEEEECCCHHHHHHHEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCC
TAFHSISLPYIELFNTRSNNPIVIFQQSLKVLMSFALK
EEEEEECCCEEEEEECCCCCCEEEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]