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The map label for this gene is aroL

Identifier: 15618946

GI number: 15618946

Start: 1192196

End: 1192726

Strand: Reverse

Name: aroL

Synonym: CPn1038

Alternate gene names: 15618946

Gene position: 1192726-1192196 (Counterclockwise)

Preceding gene: 15618947

Following gene: 15618945

Centisome position: 96.95

GC content: 40.87

Gene sequence:

>531_bases
ATGACAATTATTCTATGTGGTCTACCCACAAGCGGAAAGTCTTCGCTCGGGAAAGCTTTGGCTAAATTTCTAAACCTTCC
TTTTTATGATCTTGATGATTTAATTGTAAGCAACTACAGCAGTGCACTATACTCCTCATCTGCAGAGATCTATAAAGCTT
ATGGGGATCAGAAATTCAGTGAATGTGAAGCTCGTATTCTTGAAACTTTACCTCCAGAAGATGCCTTGATCTCCCTTGGT
GGAGGGACCTTGATGTATGAAGCCTCTTACCGAGCGATTCAAACTAGGGGAGCTCTTGTATTTCTCTCTGTAGAACTACC
TTTAATTTATGAAAGACTCGAGAAACGAGGGTTACCAGAACGGCTGAAAGAAGCCATGAAAACAAAACCTCTAAGCGAGA
TTTTAACTGAGCGCATCGACAGAATGAAAGAAATTGCTGATTACATTTTTCCCGTGGATCACGTAGATCATTCCTCGAAG
AGCTCCTTAGAACAAGCGTCTCAAGATCTCATTACCTTGTTAAAGTCATGA

Upstream 100 bases:

>100_bases
TCTGGCGATAGTCGTATTCACAACACTGCGTGCGTTAGGAAAACCTTTCCTAACTTCGTTCAGACTCTAAATATAATGGA
AGCTCGAATTGAGGAATGTC

Downstream 100 bases:

>100_bases
AAAATAGCTTTGGCTCTTTGTTTTCTTTTACAACATGGGGAGAATCCCACGGTCCCTCAATCGGAGTTGTAATCGATGGT
TGTCCCGCAGGACTCGAGCT

Product: shikimate kinase

Products: NA

Alternate protein names: SK

Number of amino acids: Translated: 176; Mature: 175

Protein sequence:

>176_residues
MTIILCGLPTSGKSSLGKALAKFLNLPFYDLDDLIVSNYSSALYSSSAEIYKAYGDQKFSECEARILETLPPEDALISLG
GGTLMYEASYRAIQTRGALVFLSVELPLIYERLEKRGLPERLKEAMKTKPLSEILTERIDRMKEIADYIFPVDHVDHSSK
SSLEQASQDLITLLKS

Sequences:

>Translated_176_residues
MTIILCGLPTSGKSSLGKALAKFLNLPFYDLDDLIVSNYSSALYSSSAEIYKAYGDQKFSECEARILETLPPEDALISLG
GGTLMYEASYRAIQTRGALVFLSVELPLIYERLEKRGLPERLKEAMKTKPLSEILTERIDRMKEIADYIFPVDHVDHSSK
SSLEQASQDLITLLKS
>Mature_175_residues
TIILCGLPTSGKSSLGKALAKFLNLPFYDLDDLIVSNYSSALYSSSAEIYKAYGDQKFSECEARILETLPPEDALISLGG
GTLMYEASYRAIQTRGALVFLSVELPLIYERLEKRGLPERLKEAMKTKPLSEILTERIDRMKEIADYIFPVDHVDHSSKS
SLEQASQDLITLLKS

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROK_CHLPN (Q9Z6M1)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   B72004
- PIR:   C86620
- RefSeq:   NP_225232.1
- RefSeq:   NP_301093.1
- RefSeq:   NP_445353.1
- RefSeq:   NP_877350.1
- ProteinModelPortal:   Q9Z6M1
- SMR:   Q9Z6M1
- GeneID:   1467757
- GeneID:   895565
- GeneID:   919810
- GeneID:   962759
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP0814
- KEGG:   cpn:CPn1038
- KEGG:   cpt:CpB1078
- TIGR:   CP_0814
- HOGENOM:   HBG414052
- OMA:   TIMHQEA
- ProtClustDB:   PRK00625
- BioCyc:   CPNE115711:CP_0814-MONOMER
- BioCyc:   CPNE115713:CPN1038-MONOMER
- BioCyc:   CPNE138677:CPJ1038-MONOMER
- BioCyc:   CPNE182082:CPB1078-MONOMER
- BRENDA:   2.7.1.71
- GO:   GO:0005737
- HAMAP:   MF_00109
- InterPro:   IPR000623
- PRINTS:   PR01100

Pfam domain/function: PF01202 SKI

EC number: =2.7.1.71

Molecular weight: Translated: 19631; Mature: 19500

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: BINDING 32-32 BINDING 81-81 BINDING 138-138

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIILCGLPTSGKSSLGKALAKFLNLPFYDLDDLIVSNYSSALYSSSAEIYKAYGDQKFS
CEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
ECEARILETLPPEDALISLGGGTLMYEASYRAIQTRGALVFLSVELPLIYERLEKRGLPE
HHHHHHHHHCCCCHHEEECCCCEEEEHHHHHHHHHCCCEEEEEECHHHHHHHHHHCCCHH
RLKEAMKTKPLSEILTERIDRMKEIADYIFPVDHVDHSSKSSLEQASQDLITLLKS
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TIILCGLPTSGKSSLGKALAKFLNLPFYDLDDLIVSNYSSALYSSSAEIYKAYGDQKFS
EEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
ECEARILETLPPEDALISLGGGTLMYEASYRAIQTRGALVFLSVELPLIYERLEKRGLPE
HHHHHHHHHCCCCHHEEECCCCEEEEHHHHHHHHHCCCEEEEEECHHHHHHHHHHCCCHH
RLKEAMKTKPLSEILTERIDRMKEIADYIFPVDHVDHSSKSSLEQASQDLITLLKS
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362