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The map label for this gene is prmA

Identifier: 15607057

GI number: 15607057

Start: 1478521

End: 1479258

Strand: Direct

Name: prmA

Synonym: aq_2102

Alternate gene names: 15607057

Gene position: 1478521-1479258 (Clockwise)

Preceding gene: 15607056

Following gene: 15607060

Centisome position: 95.31

GC content: 40.65

Gene sequence:

>738_bases
TTGATGAAGATTAAAAGGTTTGTTTACTCACTGCCCGAGGAGGAGTTCTACGAACTCGTTTACTCCCAAAACCTTTCCGT
TGAGGTCCTTGAAAGGAAAGAGATCGAAGTAATTTTCGCATCTTACAAAGAAATTGAGGGTTTAACTCCCGAGAAGGTAG
AGGAAGTAAAGGAAGACTGGGAGAATTGGAAAGAGAAGTTTAAACCTATTGAAGTTGAGGACTTTGTAATAATCCCTTCT
TGGAAAAAGCCCGTAATCGTAAAGCCTGGACTTGCCTTCGGGACGGGTCTTCACCCCACAACTCAACTCTGTATAAAAGC
CTTAAAGAAGTACTTAAAAGAGGGCATGACTGTTCTGGACGTGGGAACTGGCTCCGGAATTCTCGCAATAGTTTCGGCAC
TTCTGGGAGCTAAACGGGTAGTGGGCATAGATATAGACGAAAAAGCTGTAAATGAGTGCAGGGAAAACGCAGAGTTAAAT
AAGGTAAAAGTTGAGTGTTTCAGGGCAGAGCCAAAAGACGTAAACGAGAGTTTTGACCTTGTAGTAGCCAATCTGGAAAT
TCACATCTTTGAAAGGGTTTTAAAAGACATTCTTCCGAAGTTTAAAAAAATTGGTATATTTTCGGGACTTTACAAGGAAA
AGGATTTAAAGAGATTTGAAGAACTCCTCGGAGGTTTGAAAGTAAAGGAAGTGTTTGAAAAGGAAAACTGGTACGCGGTT
GTTGTAGAAAAAGGATAA

Upstream 100 bases:

>100_bases
AAGGGTGTTGACACCTGCGCGGGAGAATTCGTGGCGTATACACCCTACTACTATTCCTCCTATGAGAGACCTTACTACAC
TGTAGACGGGCAGGAAATCC

Downstream 100 bases:

>100_bases
AAGAAAGGGAAAAAAGAGGTTTACTCTTCGAGGGTAGAGACGTCTCCGACGTCCAGTCCGAGTTCTTCCGCTTTGAGTAT
TCTTCTCATTATCTTTCCGC

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MMKIKRFVYSLPEEEFYELVYSQNLSVEVLERKEIEVIFASYKEIEGLTPEKVEEVKEDWENWKEKFKPIEVEDFVIIPS
WKKPVIVKPGLAFGTGLHPTTQLCIKALKKYLKEGMTVLDVGTGSGILAIVSALLGAKRVVGIDIDEKAVNECRENAELN
KVKVECFRAEPKDVNESFDLVVANLEIHIFERVLKDILPKFKKIGIFSGLYKEKDLKRFEELLGGLKVKEVFEKENWYAV
VVEKG

Sequences:

>Translated_245_residues
MMKIKRFVYSLPEEEFYELVYSQNLSVEVLERKEIEVIFASYKEIEGLTPEKVEEVKEDWENWKEKFKPIEVEDFVIIPS
WKKPVIVKPGLAFGTGLHPTTQLCIKALKKYLKEGMTVLDVGTGSGILAIVSALLGAKRVVGIDIDEKAVNECRENAELN
KVKVECFRAEPKDVNESFDLVVANLEIHIFERVLKDILPKFKKIGIFSGLYKEKDLKRFEELLGGLKVKEVFEKENWYAV
VVEKG
>Mature_245_residues
MMKIKRFVYSLPEEEFYELVYSQNLSVEVLERKEIEVIFASYKEIEGLTPEKVEEVKEDWENWKEKFKPIEVEDFVIIPS
WKKPVIVKPGLAFGTGLHPTTQLCIKALKKYLKEGMTVLDVGTGSGILAIVSALLGAKRVVGIDIDEKAVNECRENAELN
KVKVECFRAEPKDVNESFDLVVANLEIHIFERVLKDILPKFKKIGIFSGLYKEKDLKRFEELLGGLKVKEVFEKENWYAV
VVEKG

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=147, Percent_Identity=44.2176870748299, Blast_Score=102, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_AQUAE (O67870)

Other databases:

- EMBL:   AE000657
- PIR:   B70480
- RefSeq:   NP_214439.1
- ProteinModelPortal:   O67870
- SMR:   O67870
- GeneID:   1193859
- GenomeReviews:   AE000657_GR
- KEGG:   aae:aq_2102
- NMPDR:   fig|224324.1.peg.1454
- HOGENOM:   HBG316226
- OMA:   VEMENNS
- ProtClustDB:   CLSK2748552
- BioCyc:   AAEO224324:AQ_2102-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 28145; Mature: 28145

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKIKRFVYSLPEEEFYELVYSQNLSVEVLERKEIEVIFASYKEIEGLTPEKVEEVKEDW
CCHHHHHHHHCCHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
ENWKEKFKPIEVEDFVIIPSWKKPVIVKPGLAFGTGLHPTTQLCIKALKKYLKEGMTVLD
HHHHHHCCCCCCCCEEEECCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEE
VGTGSGILAIVSALLGAKRVVGIDIDEKAVNECRENAELNKVKVECFRAEPKDVNESFDL
ECCCCCHHHHHHHHHCCCCEEECCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCE
VVANLEIHIFERVLKDILPKFKKIGIFSGLYKEKDLKRFEELLGGLKVKEVFEKENWYAV
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEE
VVEKG
EEECC
>Mature Secondary Structure
MMKIKRFVYSLPEEEFYELVYSQNLSVEVLERKEIEVIFASYKEIEGLTPEKVEEVKEDW
CCHHHHHHHHCCHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
ENWKEKFKPIEVEDFVIIPSWKKPVIVKPGLAFGTGLHPTTQLCIKALKKYLKEGMTVLD
HHHHHHCCCCCCCCEEEECCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEE
VGTGSGILAIVSALLGAKRVVGIDIDEKAVNECRENAELNKVKVECFRAEPKDVNESFDL
ECCCCCHHHHHHHHHCCCCEEECCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCE
VVANLEIHIFERVLKDILPKFKKIGIFSGLYKEKDLKRFEELLGGLKVKEVFEKENWYAV
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEE
VVEKG
EEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320