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The map label for this gene is dsbC [H]

Identifier: 15607050

GI number: 15607050

Start: 1471392

End: 1472108

Strand: Direct

Name: dsbC [H]

Synonym: aq_2093

Alternate gene names: 15607050

Gene position: 1471392-1472108 (Clockwise)

Preceding gene: 15607049

Following gene: 15607056

Centisome position: 94.85

GC content: 41.0

Gene sequence:

>717_bases
ATGAAAAAGTTGTCTTTTATTTTACTCTCCGCAGCATTTGTTTACGCTTCATGCCCTGAACCCTCCAAATTTGAAGAGAA
ATTAAAAGAAATAACCCAAAGGGAGTGGAAAGTTCAGGCAGTATCTGAGGTAAAAGACCTGGGATTGTGTCAGGTGGTAG
TAAAGAGAGGACTTGAACCCTTAGTTATTTACATGGACAAGGATATGAACTACTTGATTACTGGAAACGTTATTGACCTC
AAGAACGGCAAAAATCTAACTGCAGAAACCGTAAGGAAGTACGCAAAAGTATCCCCCGAAGTTTTGAAAGAGCTTGAAAA
GATGACAGACCTCAAATTCGGAAAAGGAGACAAGTACGTTTACTTTATATCAGACCCCCACTGCCCTTACTGTAACAGAC
TTGCACCAATACTGAAAAACTGGGCTGATAAAAATGACGTACAGATAAGGGTAATCTTCTACCCGCTTCCCTTCCACAAA
GGAGCGGATGAAAAGGCTGCAAGCCTTATATGTAAAAAGGATGTAAAGTACGAGGAGCTTCACACAAAAGACAAGCCCGA
AAAGGTTTGTGAGGAAGGAATGGAAAAGGTAAAGAAAAACGTAGAGTACCTCTCAAAGCTCGGTGTCACCGGAACACCTA
CACTCATCGGTATGAACGGTAAAGTTTTGGTTGGTCTTCCGAGAAGTGAAAAACAGCTTGATGAACTCGTTAAATAA

Upstream 100 bases:

>100_bases
TCTTCGTAATCCTTGAGATACTCCTTCTGTCTTTAATAGCTCTTGCAGGTTTATACTTATTCGATAAGGTAAGGGAATTT
TTTAAAGAAAGGAGGTTAAT

Downstream 100 bases:

>100_bases
TCAGCAGCACTTTATCCAGTCGAGGGGCGAGTTTACAAGCCCCAGTTTTTTATGCCACTTGTGAAACTCCTCCACGAGTT
CCGGGTACAACTCTATTAAG

Product: thiol:disulfide interchange protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MKKLSFILLSAAFVYASCPEPSKFEEKLKEITQREWKVQAVSEVKDLGLCQVVVKRGLEPLVIYMDKDMNYLITGNVIDL
KNGKNLTAETVRKYAKVSPEVLKELEKMTDLKFGKGDKYVYFISDPHCPYCNRLAPILKNWADKNDVQIRVIFYPLPFHK
GADEKAASLICKKDVKYEELHTKDKPEKVCEEGMEKVKKNVEYLSKLGVTGTPTLIGMNGKVLVGLPRSEKQLDELVK

Sequences:

>Translated_238_residues
MKKLSFILLSAAFVYASCPEPSKFEEKLKEITQREWKVQAVSEVKDLGLCQVVVKRGLEPLVIYMDKDMNYLITGNVIDL
KNGKNLTAETVRKYAKVSPEVLKELEKMTDLKFGKGDKYVYFISDPHCPYCNRLAPILKNWADKNDVQIRVIFYPLPFHK
GADEKAASLICKKDVKYEELHTKDKPEKVCEEGMEKVKKNVEYLSKLGVTGTPTLIGMNGKVLVGLPRSEKQLDELVK
>Mature_238_residues
MKKLSFILLSAAFVYASCPEPSKFEEKLKEITQREWKVQAVSEVKDLGLCQVVVKRGLEPLVIYMDKDMNYLITGNVIDL
KNGKNLTAETVRKYAKVSPEVLKELEKMTDLKFGKGDKYVYFISDPHCPYCNRLAPILKNWADKNDVQIRVIFYPLPFHK
GADEKAASLICKKDVKYEELHTKDKPEKVCEEGMEKVKKNVEYLSKLGVTGTPTLIGMNGKVLVGLPRSEKQLDELVK

Specific function: Involved in disulfide bond formation. Functions probably as a disulfide isomerase with a narrower substrate specificity than DsbC. DsbG is maintained in a reduced state by DsbD [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioredoxin family. DsbC subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081762, Length=183, Percent_Identity=28.9617486338798, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018950
- InterPro:   IPR009094
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: NA

EC number: 5.3.4.1

Molecular weight: Translated: 27105; Mature: 27105

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLSFILLSAAFVYASCPEPSKFEEKLKEITQREWKVQAVSEVKDLGLCQVVVKRGLEP
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
LVIYMDKDMNYLITGNVIDLKNGKNLTAETVRKYAKVSPEVLKELEKMTDLKFGKGDKYV
EEEEEECCCCEEEECCEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEE
YFISDPHCPYCNRLAPILKNWADKNDVQIRVIFYPLPFHKGADEKAASLICKKDVKYEEL
EEECCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHCCCCHHHH
HTKDKPEKVCEEGMEKVKKNVEYLSKLGVTGTPTLIGMNGKVLVGLPRSEKQLDELVK
HCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEECCCCHHHHHHHCC
>Mature Secondary Structure
MKKLSFILLSAAFVYASCPEPSKFEEKLKEITQREWKVQAVSEVKDLGLCQVVVKRGLEP
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
LVIYMDKDMNYLITGNVIDLKNGKNLTAETVRKYAKVSPEVLKELEKMTDLKFGKGDKYV
EEEEEECCCCEEEECCEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEE
YFISDPHCPYCNRLAPILKNWADKNDVQIRVIFYPLPFHKGADEKAASLICKKDVKYEEL
EEECCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHCCCCHHHH
HTKDKPEKVCEEGMEKVKKNVEYLSKLGVTGTPTLIGMNGKVLVGLPRSEKQLDELVK
HCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEECCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]