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The map label for this gene is nuoA1 [H]

Identifier: 15606576

GI number: 15606576

Start: 984638

End: 985018

Strand: Direct

Name: nuoA1 [H]

Synonym: aq_1385

Alternate gene names: 15606576

Gene position: 984638-985018 (Clockwise)

Preceding gene: 15606575

Following gene: 15606577

Centisome position: 63.47

GC content: 42.26

Gene sequence:

>381_bases
GTGAGAGAGATGGAGTACGTATGGATTTTAGTATTTGCTGGAATTCTCCTCGTTATAGGTCTTGTTATGATATCTCTTAA
CGCTCTGCTCGGACCCCGTGAGCCTCAAATATACGAAGACTATCCTTACGAGTGCGGTGTTCCCCTTTACGATAAAGACG
CACAGACTACCTTCCATCAGGGTTATTACCTGCTCGGTTTACTGCTCCTTCTCTTTGACATAGAAGCCGCTTTCCTCTTT
CCTTGGAGCGTTGTTTACAGGTATTTGGGAGTGTTCGGTTTTATAGAAATGTTCATATTCATATTCATACTTACATACGG
ATTGCTGTACGCATGGAAGAAAGGAGCACTTGATTGGCAATTTGAAATTGAAGAGGTTTGA

Upstream 100 bases:

>100_bases
TTTCACTCTTCGCCCTGACACTTGCAAGTGTACTTTTAGGGGTATTACCTTCTTTAGTGTGGTTTCTCATTAAGCAATCT
GCGGAAAATCTTTTTACGGG

Downstream 100 bases:

>100_bases
AGAGGTTAACTTAGTTCTTTCGGGAGGGGCTGCCAAGGGTATCGCCCATATAGGTGTTTTAAAAGCTCTGGAAGAGCTCG
GTATAAAGGTAAAGAGGCTC

Product: NADH dehydrogenase I chain A

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1 [H]

Number of amino acids: Translated: 126; Mature: 126

Protein sequence:

>126_residues
MREMEYVWILVFAGILLVIGLVMISLNALLGPREPQIYEDYPYECGVPLYDKDAQTTFHQGYYLLGLLLLLFDIEAAFLF
PWSVVYRYLGVFGFIEMFIFIFILTYGLLYAWKKGALDWQFEIEEV

Sequences:

>Translated_126_residues
MREMEYVWILVFAGILLVIGLVMISLNALLGPREPQIYEDYPYECGVPLYDKDAQTTFHQGYYLLGLLLLLFDIEAAFLF
PWSVVYRYLGVFGFIEMFIFIFILTYGLLYAWKKGALDWQFEIEEV
>Mature_126_residues
MREMEYVWILVFAGILLVIGLVMISLNALLGPREPQIYEDYPYECGVPLYDKDAQTTFHQGYYLLGLLLLLFDIEAAFLF
PWSVVYRYLGVFGFIEMFIFIFILTYGLLYAWKKGALDWQFEIEEV

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788625, Length=108, Percent_Identity=36.1111111111111, Blast_Score=69, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023043
- InterPro:   IPR000440 [H]

Pfam domain/function: PF00507 Oxidored_q4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 14833; Mature: 14833

Theoretical pI: Translated: 4.01; Mature: 4.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREMEYVWILVFAGILLVIGLVMISLNALLGPREPQIYEDYPYECGVPLYDKDAQTTFHQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
GYYLLGLLLLLFDIEAAFLFPWSVVYRYLGVFGFIEMFIFIFILTYGLLYAWKKGALDWQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
FEIEEV
EEECCC
>Mature Secondary Structure
MREMEYVWILVFAGILLVIGLVMISLNALLGPREPQIYEDYPYECGVPLYDKDAQTTFHQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
GYYLLGLLLLLFDIEAAFLFPWSVVYRYLGVFGFIEMFIFIFILTYGLLYAWKKGALDWQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
FEIEEV
EEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA