Click here to switch to the map view.

The map label for this gene is nuoN1

Identifier: 15606526

GI number: 15606526

Start: 936880

End: 938274

Strand: Direct

Name: nuoN1

Synonym: aq_1322

Alternate gene names: 15606526

Gene position: 936880-938274 (Clockwise)

Preceding gene: 15606525

Following gene: 15606527

Centisome position: 60.39

GC content: 45.45

Gene sequence:

>1395_bases
TTGAACTGGAACGCTATACTTCCCGAAGCCATACTCGCAATAGGAATTCTCACGGTTTTCATACTTGAGCTATTCCTTGA
AAGGAAGCATTACAAGTTCTTGAGTGTCCTTGCTTTTATATTCGTTGTCCTTTCAGGGTATTCAATATTCTTCGTAAATT
ATCCTGCAAAACTCTTTTTTGACGGCTTTTCCGTAGATGCTCTTAACTTAATCGGCAAGCTTTTCATTTTGGCAGTCACC
GGGTTTGTACTCCTTTCTTCCTACGACTACTTCTCCAAGAAGAACTCCCAGTATGGAGAACTCCCATACCTCTACCTGAT
AGCAACACTCGGTTTAATGGTTATGATTTCCTCCGACAACCTTGCGATAATCTTCACGGGACTGGAACTCGCCTCCATCA
CCATGTACATACTCGTGGGTTTGTTCAGAAGGGAGTATCTCTCAAAGGAAGGAGCTTTTAAGTACTTGGTAATAGGAACT
ACTGGAACGTCCATGTACGCACTCGGTTCAGCACTCGTTTACGCCTCAAGCGGTTCTATGGTTCTGAGTCCCGTAAAAGA
AGAGAACACTTTATTTGCCTTAGGTGTGATACTGATAATTTCCGCCCTTGCTCTGAAGGTTTCCGCTGTTCCCTTCCACT
TCTGGACGCCTGACGCTTACGAGGGAGCACCTACGCCCACTACAGCTTACCTTTCAACTGTTCCCAAAATCGGTATGTAC
TTCCTCTTTGTCAAACTCACCATGTACCTCTTTTCCGCGTTCCCCGATTGGAAGTACGTGGTTATGCTTCTCGCTGTACT
TTCCATGTTCTACGGAAATATAGTCGCTTACGCTCAGAAGTCCGTAAAGAGACTGCTCGCCTACTCCTCAATAGCACACG
CAGGATACTTCCTTACCGCTTTAACCGCTGTGGATAAACACCTCTTTTCCGCACTTCTCTTTTACGTGTTCGTTTACGCT
CTTGCAACCGTCGGAGCGTTTACGGTTCTCGCTATCCTTGAGAAAAAGGAAGGCTGGACACATCACTTCTTAGATTTCAA
AGGATTAAAAGAGGAAAACCCTGTTCTCGCTTCTATGCTAGCACTCTTCCTCTTTGCCTTGATAGGTATCCCTCCCGCTG
CTGTATTTCTGGGTAAGCTCGGTATATTCTTCGGGCTAGTTAAAACCGATATGTTCGCCCTTGGTATCCTCTTTGCCATA
GCGAGTTTAATTTCCGCAGGGTATTACCTAAAGGTTATCGTTTACATGTTCCTCTACTCGGGAGAAGTAAGACACGGTCA
GACTACGGTTTCCGCTGGAGAGGCTTTCACGGTTCTCGGTACGGCTTTCCTCGTTATATTCTTTGGTCTATTTCCCCATG
TGGTTCTTGACTTTATCCTGCGTGCCCTCTCTTAA

Upstream 100 bases:

>100_bases
GCACTGATAATTGGCATGGCTCTCGTTATGGGAATATACCCTTATCCCTTTGTGAAGATAGTGGAACACACTTCTAAACT
CGTGTTCGGAGGTTGAAGCC

Downstream 100 bases:

>100_bases
TTAATTTTTATGTACACGGCAATAATCCTCGCTGCTGGTAGAGGTAGCAGAATAGGTTTCAGGAAACAGTTTGCAACCCT
TTGCGGAAAGCCTCTATTTA

Product: NADH dehydrogenase I chain N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N 1; NDH-1 subunit N 1

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MNWNAILPEAILAIGILTVFILELFLERKHYKFLSVLAFIFVVLSGYSIFFVNYPAKLFFDGFSVDALNLIGKLFILAVT
GFVLLSSYDYFSKKNSQYGELPYLYLIATLGLMVMISSDNLAIIFTGLELASITMYILVGLFRREYLSKEGAFKYLVIGT
TGTSMYALGSALVYASSGSMVLSPVKEENTLFALGVILIISALALKVSAVPFHFWTPDAYEGAPTPTTAYLSTVPKIGMY
FLFVKLTMYLFSAFPDWKYVVMLLAVLSMFYGNIVAYAQKSVKRLLAYSSIAHAGYFLTALTAVDKHLFSALLFYVFVYA
LATVGAFTVLAILEKKEGWTHHFLDFKGLKEENPVLASMLALFLFALIGIPPAAVFLGKLGIFFGLVKTDMFALGILFAI
ASLISAGYYLKVIVYMFLYSGEVRHGQTTVSAGEAFTVLGTAFLVIFFGLFPHVVLDFILRALS

Sequences:

>Translated_464_residues
MNWNAILPEAILAIGILTVFILELFLERKHYKFLSVLAFIFVVLSGYSIFFVNYPAKLFFDGFSVDALNLIGKLFILAVT
GFVLLSSYDYFSKKNSQYGELPYLYLIATLGLMVMISSDNLAIIFTGLELASITMYILVGLFRREYLSKEGAFKYLVIGT
TGTSMYALGSALVYASSGSMVLSPVKEENTLFALGVILIISALALKVSAVPFHFWTPDAYEGAPTPTTAYLSTVPKIGMY
FLFVKLTMYLFSAFPDWKYVVMLLAVLSMFYGNIVAYAQKSVKRLLAYSSIAHAGYFLTALTAVDKHLFSALLFYVFVYA
LATVGAFTVLAILEKKEGWTHHFLDFKGLKEENPVLASMLALFLFALIGIPPAAVFLGKLGIFFGLVKTDMFALGILFAI
ASLISAGYYLKVIVYMFLYSGEVRHGQTTVSAGEAFTVLGTAFLVIFFGLFPHVVLDFILRALS
>Mature_464_residues
MNWNAILPEAILAIGILTVFILELFLERKHYKFLSVLAFIFVVLSGYSIFFVNYPAKLFFDGFSVDALNLIGKLFILAVT
GFVLLSSYDYFSKKNSQYGELPYLYLIATLGLMVMISSDNLAIIFTGLELASITMYILVGLFRREYLSKEGAFKYLVIGT
TGTSMYALGSALVYASSGSMVLSPVKEENTLFALGVILIISALALKVSAVPFHFWTPDAYEGAPTPTTAYLSTVPKIGMY
FLFVKLTMYLFSAFPDWKYVVMLLAVLSMFYGNIVAYAQKSVKRLLAYSSIAHAGYFLTALTAVDKHLFSALLFYVFVYA
LATVGAFTVLAILEKKEGWTHHFLDFKGLKEENPVLASMLALFLFALIGIPPAAVFLGKLGIFFGLVKTDMFALGILFAI
ASLISAGYYLKVIVYMFLYSGEVRHGQTTVSAGEAFTVLGTAFLVIFFGLFPHVVLDFILRALS

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family

Homologues:

Organism=Escherichia coli, GI145693160, Length=488, Percent_Identity=29.7131147540984, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI1788831, Length=350, Percent_Identity=26.2857142857143, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1788613, Length=347, Percent_Identity=26.2247838616715, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788614, Length=257, Percent_Identity=23.3463035019455, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUON1_AQUAE (O67342)

Other databases:

- EMBL:   AE000657
- PIR:   C70414
- RefSeq:   NP_213906.1
- GeneID:   1192780
- GenomeReviews:   AE000657_GR
- KEGG:   aae:aq_1322
- NMPDR:   fig|224324.1.peg.921
- HOGENOM:   HBG747830
- OMA:   GAYINDS
- PhylomeDB:   O67342
- ProtClustDB:   CLSK2299661
- BioCyc:   AAEO224324:AQ_1322-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_00445
- InterPro:   IPR010096
- InterPro:   IPR001750
- TIGRFAMs:   TIGR01770

Pfam domain/function: PF00361 Oxidored_q1

EC number: =1.6.99.5

Molecular weight: Translated: 51287; Mature: 51287

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xda81ec0)-; HASH(0xd9c9428)-; HASH(0xcdcc358)-; HASH(0xc6f1aac)-; HASH(0xda3a824)-; HASH(0xc76ddc0)-; HASH(0xd92dc58)-; HASH(0xcfbd668)-; HASH(0xd614e50)-; HASH(0xd260158)-; HASH(0xda3a794)-; HASH(0x4069e820)-; HASH(0xdbc554c)-; HASH(0xd2600e0)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWNAILPEAILAIGILTVFILELFLERKHYKFLSVLAFIFVVLSGYSIFFVNYPAKLFF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHC
DGFSVDALNLIGKLFILAVTGFVLLSSYDYFSKKNSQYGELPYLYLIATLGLMVMISSDN
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHHHHHHHEEEECCCC
LAIIFTGLELASITMYILVGLFRREYLSKEGAFKYLVIGTTGTSMYALGSALVYASSGSM
EEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHEEECCCCE
VLSPVKEENTLFALGVILIISALALKVSAVPFHFWTPDAYEGAPTPTTAYLSTVPKIGMY
EEECCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHH
FLFVKLTMYLFSAFPDWKYVVMLLAVLSMFYGNIVAYAQKSVKRLLAYSSIAHAGYFLTA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTAVDKHLFSALLFYVFVYALATVGAFTVLAILEKKEGWTHHFLDFKGLKEENPVLASML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCHHHHHH
ALFLFALIGIPPAAVFLGKLGIFFGLVKTDMFALGILFAIASLISAGYYLKVIVYMFLYS
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
GEVRHGQTTVSAGEAFTVLGTAFLVIFFGLFPHVVLDFILRALS
CCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MNWNAILPEAILAIGILTVFILELFLERKHYKFLSVLAFIFVVLSGYSIFFVNYPAKLFF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHC
DGFSVDALNLIGKLFILAVTGFVLLSSYDYFSKKNSQYGELPYLYLIATLGLMVMISSDN
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHHHHHHHEEEECCCC
LAIIFTGLELASITMYILVGLFRREYLSKEGAFKYLVIGTTGTSMYALGSALVYASSGSM
EEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHEEECCCCE
VLSPVKEENTLFALGVILIISALALKVSAVPFHFWTPDAYEGAPTPTTAYLSTVPKIGMY
EEECCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHH
FLFVKLTMYLFSAFPDWKYVVMLLAVLSMFYGNIVAYAQKSVKRLLAYSSIAHAGYFLTA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTAVDKHLFSALLFYVFVYALATVGAFTVLAILEKKEGWTHHFLDFKGLKEENPVLASML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCHHHHHH
ALFLFALIGIPPAAVFLGKLGIFFGLVKTDMFALGILFAIASLISAGYYLKVIVYMFLYS
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
GEVRHGQTTVSAGEAFTVLGTAFLVIFFGLFPHVVLDFILRALS
CCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9537320