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The map label for this gene is ftsW [H]

Identifier: 15606396

GI number: 15606396

Start: 796183

End: 797529

Strand: Direct

Name: ftsW [H]

Synonym: aq_1139

Alternate gene names: 15606396

Gene position: 796183-797529 (Clockwise)

Preceding gene: 15606395

Following gene: 15606397

Centisome position: 51.32

GC content: 41.72

Gene sequence:

>1347_bases
ATGAAATTTGCGGAGAAAATATACCCCGATAAAGTTATCCTTACGCTCCTGTTCGTGTTCTTTCTCCTCTCCCAAACCTT
TGTGTTTATAAAAAACGTTGTTCCCCTTCTCGTTCAGTACAACCCCTACGCTGTGCTAAAGTACGAGGAGAGAAAAAATA
GGTGGAGGTTGTTTACTCATGAAAACTTGAGGTACTTTTACGACTTGAAGACCAAAAAACTCTACCCGCTTCCACTTCTT
AAAAACGAACCCTACAGGTTCAAACCCGCTTTAAAGGGAGAGTACTTGGTCAACTTTGAAGGAGTTAAATACAGGATAAA
GCCCTTTAAGGAATTGTTTCCCAAAAAACTCTTTATTGCCTCCTTTAAAAACGTAAAGTTACTCCTTTTCTGGGTTTTCG
GTTTTTTGATTATGTATCTCTTTACTAGGATAAACTACAAGGCTTTTAGGAATAAGAAGTTTGTTTACGTTCTAGTATCA
GTATCTTTACTTCTTTTAGTGCTCGTTCTGGTAAAGAAGTTTTTAAATCCAAATTCGCATATGCCCACGAGGTGGCTCTT
CGGGACGAGCTTTCAACCCTCCGAGTTTTCAAAAATCGTACTTATCCTTTTTCTCGCTTACTACATAGGCGTTAAAGGGG
AAATAGAAAAGATAAGCAACTTCTTCTTTGCCCTCGGTGTCCTAGTCATACACGCAAGTTTGGTGGCTCTCCAAACGGAC
CTAGGTATGGCTATATTCTACATAGTCCTCGGTTCTTCCTTGATGTTCGTGGGCGGAACTCCCTGGAGGATACTCATTCC
AAGTTCTTTTATCCTCGGTCTTGCGGGAGTGTTCTTCATTTCCGCAAACATGGAAACGGTAAAGAAGCGTTTTTCCGGCT
GGCTTGATCCCTTTGCCGATCCCTACGACAGGGGATACCAGATAATTAAGTCTCTGGAAGCGGTTATAAACGGAGGTTTC
TTAGGGCAGGGACTGGGAAAGGGGCTTTACGCGGCTGTCTACATAAGGGAATCCGACACGGACTACGTAATAAGCTTAAT
CGTGGAGAACTTAGGAGTAATAGGCTTTTTCTTTATCCTCTCCCTTCAGTTTCTCTTTGCCCTGAGGCTTTTCAAGTACG
CTGTGAGGATTTACGGGATGTACGAAAAGATAATAATCCTCGGCGTTGCCCTGAATTTCCTATATTCAGTATTCGTCAAT
TACGCAATGGCTTTAAACATACTGCCGCCTAAAGGTATAGCCCTGCCCTTTATAAGCTACGGAGTCAGTAATTTGCTTTC
CAATATGATAATGCTGGGAATAGTTGGTTCTATATACAGGAGAAACAGCGATGTATTAAACTTATGA

Upstream 100 bases:

>100_bases
GGAGTTGAACTCGCCCTTTCCATAGTAAAAGTTTGGCTGGAAACACCTTTCGAAGGGGGAAGGCACTTAAAGAGACTCGA
GATAATATCAGAGATAGAAG

Downstream 100 bases:

>100_bases
ATTATGAAGAAAAAGAGGGTAATTCTCGCATACTCGGGCGGACTCGACACATCCATAATAGTGAGATGGCTCACGGAAAA
AGGGTACGAGGTAATAACAT

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MKFAEKIYPDKVILTLLFVFFLLSQTFVFIKNVVPLLVQYNPYAVLKYEERKNRWRLFTHENLRYFYDLKTKKLYPLPLL
KNEPYRFKPALKGEYLVNFEGVKYRIKPFKELFPKKLFIASFKNVKLLLFWVFGFLIMYLFTRINYKAFRNKKFVYVLVS
VSLLLLVLVLVKKFLNPNSHMPTRWLFGTSFQPSEFSKIVLILFLAYYIGVKGEIEKISNFFFALGVLVIHASLVALQTD
LGMAIFYIVLGSSLMFVGGTPWRILIPSSFILGLAGVFFISANMETVKKRFSGWLDPFADPYDRGYQIIKSLEAVINGGF
LGQGLGKGLYAAVYIRESDTDYVISLIVENLGVIGFFFILSLQFLFALRLFKYAVRIYGMYEKIIILGVALNFLYSVFVN
YAMALNILPPKGIALPFISYGVSNLLSNMIMLGIVGSIYRRNSDVLNL

Sequences:

>Translated_448_residues
MKFAEKIYPDKVILTLLFVFFLLSQTFVFIKNVVPLLVQYNPYAVLKYEERKNRWRLFTHENLRYFYDLKTKKLYPLPLL
KNEPYRFKPALKGEYLVNFEGVKYRIKPFKELFPKKLFIASFKNVKLLLFWVFGFLIMYLFTRINYKAFRNKKFVYVLVS
VSLLLLVLVLVKKFLNPNSHMPTRWLFGTSFQPSEFSKIVLILFLAYYIGVKGEIEKISNFFFALGVLVIHASLVALQTD
LGMAIFYIVLGSSLMFVGGTPWRILIPSSFILGLAGVFFISANMETVKKRFSGWLDPFADPYDRGYQIIKSLEAVINGGF
LGQGLGKGLYAAVYIRESDTDYVISLIVENLGVIGFFFILSLQFLFALRLFKYAVRIYGMYEKIIILGVALNFLYSVFVN
YAMALNILPPKGIALPFISYGVSNLLSNMIMLGIVGSIYRRNSDVLNL
>Mature_448_residues
MKFAEKIYPDKVILTLLFVFFLLSQTFVFIKNVVPLLVQYNPYAVLKYEERKNRWRLFTHENLRYFYDLKTKKLYPLPLL
KNEPYRFKPALKGEYLVNFEGVKYRIKPFKELFPKKLFIASFKNVKLLLFWVFGFLIMYLFTRINYKAFRNKKFVYVLVS
VSLLLLVLVLVKKFLNPNSHMPTRWLFGTSFQPSEFSKIVLILFLAYYIGVKGEIEKISNFFFALGVLVIHASLVALQTD
LGMAIFYIVLGSSLMFVGGTPWRILIPSSFILGLAGVFFISANMETVKKRFSGWLDPFADPYDRGYQIIKSLEAVINGGF
LGQGLGKGLYAAVYIRESDTDYVISLIVENLGVIGFFFILSLQFLFALRLFKYAVRIYGMYEKIIILGVALNFLYSVFVN
YAMALNILPPKGIALPFISYGVSNLLSNMIMLGIVGSIYRRNSDVLNL

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=311, Percent_Identity=27.9742765273312, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1786853, Length=318, Percent_Identity=31.4465408805031, Blast_Score=105, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 51688; Mature: 51688

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFAEKIYPDKVILTLLFVFFLLSQTFVFIKNVVPLLVQYNPYAVLKYEERKNRWRLFTH
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEECCCCCCEEEEEE
ENLRYFYDLKTKKLYPLPLLKNEPYRFKPALKGEYLVNFEGVKYRIKPFKELFPKKLFIA
CCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEECHHHHHCCHHHHHH
SFKNVKLLLFWVFGFLIMYLFTRINYKAFRNKKFVYVLVSVSLLLLVLVLVKKFLNPNSH
HHCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCC
MPTRWLFGTSFQPSEFSKIVLILFLAYYIGVKGEIEKISNFFFALGVLVIHASLVALQTD
CCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGMAIFYIVLGSSLMFVGGTPWRILIPSSFILGLAGVFFISANMETVKKRFSGWLDPFAD
HHHHHHHHHHCCCEEEECCCCEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
PYDRGYQIIKSLEAVINGGFLGQGLGKGLYAAVYIRESDTDYVISLIVENLGVIGFFFIL
HHHHHHHHHHHHHHHHCCCCHHCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHH
SLQFLFALRLFKYAVRIYGMYEKIIILGVALNFLYSVFVNYAMALNILPPKGIALPFISY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
GVSNLLSNMIMLGIVGSIYRRNSDVLNL
HHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKFAEKIYPDKVILTLLFVFFLLSQTFVFIKNVVPLLVQYNPYAVLKYEERKNRWRLFTH
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEECCCCCCEEEEEE
ENLRYFYDLKTKKLYPLPLLKNEPYRFKPALKGEYLVNFEGVKYRIKPFKELFPKKLFIA
CCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEECHHHHHCCHHHHHH
SFKNVKLLLFWVFGFLIMYLFTRINYKAFRNKKFVYVLVSVSLLLLVLVLVKKFLNPNSH
HHCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCC
MPTRWLFGTSFQPSEFSKIVLILFLAYYIGVKGEIEKISNFFFALGVLVIHASLVALQTD
CCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGMAIFYIVLGSSLMFVGGTPWRILIPSSFILGLAGVFFISANMETVKKRFSGWLDPFAD
HHHHHHHHHHCCCEEEECCCCEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
PYDRGYQIIKSLEAVINGGFLGQGLGKGLYAAVYIRESDTDYVISLIVENLGVIGFFFIL
HHHHHHHHHHHHHHHHCCCCHHCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHH
SLQFLFALRLFKYAVRIYGMYEKIIILGVALNFLYSVFVNYAMALNILPPKGIALPFISY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
GVSNLLSNMIMLGIVGSIYRRNSDVLNL
HHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]