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The map label for this gene is fdhE

Identifier: 15606334

GI number: 15606334

Start: 725987

End: 726838

Strand: Direct

Name: fdhE

Synonym: aq_1051

Alternate gene names: 15606334

Gene position: 725987-726838 (Clockwise)

Preceding gene: 15606333

Following gene: 15606335

Centisome position: 46.8

GC content: 31.1

Gene sequence:

>852_bases
ATGTGGGGTGGTGAAATGAATATATTCAAGCAAAAAGAAAGAGAATTTGCTTTAAATAGGATTCCTGTTTTGAAGGAAAA
ATTTCCAGAATCTAACCAAATACTGAACTTTTTATCTCATATTCTTGAATACCACAATTCTATTATTTCGGAGATTTCAG
ATTTAAGTATATCTCTTGATAACCAAAATATAGAAAGTAGATTAGGAAAAGGTAAACCCGCTTTAAAGCTTTCAGAATAT
GATTTCGAACCTTTCCTCAAGTACTTTTATCCTTTATTGAATATTGTCTATGAACATGGTACCCCACAAATGAAAGAAAG
AGTAGAGCATTTACAAAGTCTTGAAAAAAAAGAAATATTATCTTTAATATCTTCTTTTTTAGAAAATGGAATTTCGGACG
ATATGCTGAGATTCTTCCTTATATCTTATCTCCAACCTATACTCTATACATTTGCAGATAAGGTTAAATTCGAACACGAA
AGATGGTTTAAAAATTACTGTCCAGTTTGTGGGTCTAAACCGTCAGTTTCATTCATTATGGATACGGAAGATTGGGAAGG
AGCACGTTTTCTGAGATGTAGTGTTTGTCTTACTGACTGGCTCTATGTAAGAACAAAATGTGTAAATTGCGGCAATGTAG
AAGACGATAGTTTAGATTATTTTATAAGTTCAGAATTAGATTATATAGAAATTCAAACATGTAAAAAGTGTAATAGTTAT
ATAAAAATCATAGATCTTAGAAAAGATGGACTTGCAGTGCCTGATTTAGAAGATATAGCTTCTGTTAGTCTTGATTTATG
GGCTCAGGAACAAGGTTTTATAAAAGTTGAAAGGAATTTTATGGGGTACTAG

Upstream 100 bases:

>100_bases
AAAATAGCTTATTTAAAGAAGGCGGAACGGCACTCGTCATTCATGGCGGACCTGACGACTACAAGTCTGATCCCGCGGGA
AACGCAGGAAAAAGGATAGC

Downstream 100 bases:

>100_bases
CTGTGAAAAGGAGAACGTTTTTAGAATCTCTTCTATTTCTTTTTTTAATAAAAACGGGTTTTAGTATGGAACGAAAGATA
GACGTTTTAGGATGTACCTT

Product: formate dehydrogenase formation protein FdhE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MWGGEMNIFKQKEREFALNRIPVLKEKFPESNQILNFLSHILEYHNSIISEISDLSISLDNQNIESRLGKGKPALKLSEY
DFEPFLKYFYPLLNIVYEHGTPQMKERVEHLQSLEKKEILSLISSFLENGISDDMLRFFLISYLQPILYTFADKVKFEHE
RWFKNYCPVCGSKPSVSFIMDTEDWEGARFLRCSVCLTDWLYVRTKCVNCGNVEDDSLDYFISSELDYIEIQTCKKCNSY
IKIIDLRKDGLAVPDLEDIASVSLDLWAQEQGFIKVERNFMGY

Sequences:

>Translated_283_residues
MWGGEMNIFKQKEREFALNRIPVLKEKFPESNQILNFLSHILEYHNSIISEISDLSISLDNQNIESRLGKGKPALKLSEY
DFEPFLKYFYPLLNIVYEHGTPQMKERVEHLQSLEKKEILSLISSFLENGISDDMLRFFLISYLQPILYTFADKVKFEHE
RWFKNYCPVCGSKPSVSFIMDTEDWEGARFLRCSVCLTDWLYVRTKCVNCGNVEDDSLDYFISSELDYIEIQTCKKCNSY
IKIIDLRKDGLAVPDLEDIASVSLDLWAQEQGFIKVERNFMGY
>Mature_283_residues
MWGGEMNIFKQKEREFALNRIPVLKEKFPESNQILNFLSHILEYHNSIISEISDLSISLDNQNIESRLGKGKPALKLSEY
DFEPFLKYFYPLLNIVYEHGTPQMKERVEHLQSLEKKEILSLISSFLENGISDDMLRFFLISYLQPILYTFADKVKFEHE
RWFKNYCPVCGSKPSVSFIMDTEDWEGARFLRCSVCLTDWLYVRTKCVNCGNVEDDSLDYFISSELDYIEIQTCKKCNSY
IKIIDLRKDGLAVPDLEDIASVSLDLWAQEQGFIKVERNFMGY

Specific function: Necessary for formate dehydrogenase activity

COG id: COG3058

COG function: function code O; Uncharacterized protein involved in formate dehydrogenase formation

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fdhE family

Homologues:

Organism=Escherichia coli, GI1790324, Length=275, Percent_Identity=25.0909090909091, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FDHE_AQUAE (O67150)

Other databases:

- EMBL:   AE000657
- PIR:   C70390
- RefSeq:   NP_213713.1
- ProteinModelPortal:   O67150
- SMR:   O67150
- GeneID:   1193784
- GenomeReviews:   AE000657_GR
- KEGG:   aae:aq_1051
- NMPDR:   fig|224324.1.peg.728
- OMA:   LSHILEY
- PhylomeDB:   O67150
- ProtClustDB:   CLSK2748406
- BioCyc:   AAEO224324:AQ_1051-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00611
- InterPro:   IPR006452
- PIRSF:   PIRSF018296

Pfam domain/function: PF04216 FdhE

EC number: NA

Molecular weight: Translated: 33169; Mature: 33169

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWGGEMNIFKQKEREFALNRIPVLKEKFPESNQILNFLSHILEYHNSIISEISDLSISLD
CCCCCCHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEEC
NQNIESRLGKGKPALKLSEYDFEPFLKYFYPLLNIVYEHGTPQMKERVEHLQSLEKKEIL
CCCHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
SLISSFLENGISDDMLRFFLISYLQPILYTFADKVKFEHERWFKNYCPVCGSKPSVSFIM
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
DTEDWEGARFLRCSVCLTDWLYVRTKCVNCGNVEDDSLDYFISSELDYIEIQTCKKCNSY
ECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCEEEHHHHHHHCCC
IKIIDLRKDGLAVPDLEDIASVSLDLWAQEQGFIKVERNFMGY
EEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCC
>Mature Secondary Structure
MWGGEMNIFKQKEREFALNRIPVLKEKFPESNQILNFLSHILEYHNSIISEISDLSISLD
CCCCCCHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEEC
NQNIESRLGKGKPALKLSEYDFEPFLKYFYPLLNIVYEHGTPQMKERVEHLQSLEKKEIL
CCCHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
SLISSFLENGISDDMLRFFLISYLQPILYTFADKVKFEHERWFKNYCPVCGSKPSVSFIM
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
DTEDWEGARFLRCSVCLTDWLYVRTKCVNCGNVEDDSLDYFISSELDYIEIQTCKKCNSY
ECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCEEEHHHHHHHCCC
IKIIDLRKDGLAVPDLEDIASVSLDLWAQEQGFIKVERNFMGY
EEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320