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The map label for this gene is glgP

Identifier: 15606115

GI number: 15606115

Start: 491380

End: 493458

Strand: Direct

Name: glgP

Synonym: aq_717

Alternate gene names: 15606115

Gene position: 491380-493458 (Clockwise)

Preceding gene: 15606108

Following gene: 15606116

Centisome position: 31.67

GC content: 42.62

Gene sequence:

>2079_bases
ATGGAAGAAGAAAAAGTAAAAGAGGGATTGTGGGAGTTAGCTTACAACCTGTGGTGGACGTGGAATCCGCCGGCTAAGGA
ATTATTCAGAAGCATTGACCCGCTTTTGTGGAAGGAAACTAAGGAAAACCCCATTGAGTTATTGAGGAAAACCAAACTCC
TTGAAAACAAGCTCAAAGACGAAGATTTTATATCTCACTTCAAGTACGTTTATTCCCTTTACAAAACCTACATGAACAGG
CATTCGAAATACGAGGATACGTATAAGAAGCCTATAGTTTTCCTGTCTCCCGAGTACGGACTTCACCACACACTACTTAT
ATACGCGGGGGGACTGGGCTTTTTAGCAGGAGATATACTCAAGGAGAGCAGTGACTTGGGATTTCCGCTTATAGGTGTCG
GGTTTATGTACCCTCAGGGCTACGTAAAGCAGAGGATAAGGGTTGACGGATGGCAGGAAGACCTTGACGCACAAAATCAA
AAGGAATTAATGCCCGTTAAAAAAGTTCTGGACAAAGAAGGAAAATGGCTCAAGTGCTACGTTTACGTAAGGGATGAAAA
GGTTTACTTTGGAGTCTGGGAAGTTAACGTGGGAAAGACAAAGCTCTACCTTCTTGACACGAACGTAGAGGAAAATACTC
CCTGGAACAGGGAAATATCCTCAAGACTCTACGTTCCGGACAAAGACCTGAGGTTAAGACAACAGATAGTTCTTGGTTTT
GGCACCGTAATACTCCTTGAAAAGCTGGGCATTGATGCAGGAGGTTTTCACATAAACGAAGATTATCCCTCGTTCGTGTT
CCTTGCAGAAATATTTAAACTTCTAAAAAAAGGTCTGACCTGGGATAAGGCGATAGAAGAAGTAAGAAAGATTTCTCTCT
TTACCACGCACACACCACTACGGGTTGCCGTAAATACTTATCCCTTCCACATGATAGAGGAACAGTTTCTATTCGTTAAG
GATGTTTACGGAATAGACGTAAAGAAAGTTCTGGAACTCGGAACGAATCCTGAAGACCCTTCGGAGGGTTTTAACAGTAC
GATTATGTCCCTCAGACTCGCAAAGTACGTAAACGCAGTGAGTAAAAGACATCAAGAAGTTTCAAGCAAGATGTGGAGTT
TTTTATTTAAAGAAAAGGAGAATCCAATAGATTACGTAACGAACGGTGTTCACTTTCCCACATGGATTTGTTCAGATTTG
AGAAGACTGTACGAGGAGTATTTGGGAGAGAACTTTGTGGAACTTCACGACCACAAGTCTCTGTGGGAATTAATAAGAGA
CATACCCGACGAAGAACTGTGGGAATATCACATAAGAAATAAAGAAAGACTTATTGAGCACATAAAAGACAGGGCAAGGG
AAAGGTGGGTCAAGGAAAAAGCGGATCCTTCAATCCTTATGGCCGAAGGTCTGTTCCTTGATTCTGACGTTCTTACGGTC
GGTTTTGCGAGGAGGATGACCGGTTACAAAAGACCGGATCTTATATTCACGGATGTAGAACGCTTAAAAAAGATAGTGAA
TGATTCGGAAAGACCTGTTCAGATAATATTCGCGGGAAAGGCTCATCCGGCTGATATCGAAGGGAAAAAGATAATCCAGA
GAATATTTAACTTTGCGAAAGATCCGGAATTTGGGGGAAGAATAGCTTTCGTTGAAGATTACGACGAACTCCTTGCCCAT
TACATGGTGAGGGGTGTGGACGTATGGTTGAACAACCCTCTTCCTCCCCTTGAAGCCTGCGGGACAAGCGGTATGAAAGC
TTCTATGAACGGAGTGCTTCACCTTTCAATACTTGACGGTTGGTGGATTGAGGGTTATAACGGAAAGAACGGTTGGGCTT
TCGGAGATTACGAAGTTGAAGGAGACAGGAACAGAGCGGATGCGGAGGCCATTTACAACATCCTTGAGAATGAAGTAATC
CCCCTTTATTACGAAAGGGACGAGAGGGGAGTGCCAGTTAAGTGGATAAGTATGATGAAGGAAGCTATAAAAAGCATTAC
CCCTAACTTTTGCTCCAGAAGGATGTTAAAAGATTACATAAATAAGTTCTATTCAAAAATTTTAAAGGAGGAGGGATGA

Upstream 100 bases:

>100_bases
TCACAAGATTCATTTTAAAAAACTGCTTACACAGGCGGCTTCTGTCCCCGTATCATAGATACGCGGTTTTAGCCCGCGGA
TTTACTATAAAATACAAGTA

Downstream 100 bases:

>100_bases
AAGGTGTAATCCTTGCGGGAGGATTTGGAACTAGGATTCAACCCCTTACAAACAGCATTCCCAAACCCATGCTTCCCGTC
GCAAACAGACCCATAATGGA

Product: glycogen phosphorylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 692; Mature: 692

Protein sequence:

>692_residues
MEEEKVKEGLWELAYNLWWTWNPPAKELFRSIDPLLWKETKENPIELLRKTKLLENKLKDEDFISHFKYVYSLYKTYMNR
HSKYEDTYKKPIVFLSPEYGLHHTLLIYAGGLGFLAGDILKESSDLGFPLIGVGFMYPQGYVKQRIRVDGWQEDLDAQNQ
KELMPVKKVLDKEGKWLKCYVYVRDEKVYFGVWEVNVGKTKLYLLDTNVEENTPWNREISSRLYVPDKDLRLRQQIVLGF
GTVILLEKLGIDAGGFHINEDYPSFVFLAEIFKLLKKGLTWDKAIEEVRKISLFTTHTPLRVAVNTYPFHMIEEQFLFVK
DVYGIDVKKVLELGTNPEDPSEGFNSTIMSLRLAKYVNAVSKRHQEVSSKMWSFLFKEKENPIDYVTNGVHFPTWICSDL
RRLYEEYLGENFVELHDHKSLWELIRDIPDEELWEYHIRNKERLIEHIKDRARERWVKEKADPSILMAEGLFLDSDVLTV
GFARRMTGYKRPDLIFTDVERLKKIVNDSERPVQIIFAGKAHPADIEGKKIIQRIFNFAKDPEFGGRIAFVEDYDELLAH
YMVRGVDVWLNNPLPPLEACGTSGMKASMNGVLHLSILDGWWIEGYNGKNGWAFGDYEVEGDRNRADAEAIYNILENEVI
PLYYERDERGVPVKWISMMKEAIKSITPNFCSRRMLKDYINKFYSKILKEEG

Sequences:

>Translated_692_residues
MEEEKVKEGLWELAYNLWWTWNPPAKELFRSIDPLLWKETKENPIELLRKTKLLENKLKDEDFISHFKYVYSLYKTYMNR
HSKYEDTYKKPIVFLSPEYGLHHTLLIYAGGLGFLAGDILKESSDLGFPLIGVGFMYPQGYVKQRIRVDGWQEDLDAQNQ
KELMPVKKVLDKEGKWLKCYVYVRDEKVYFGVWEVNVGKTKLYLLDTNVEENTPWNREISSRLYVPDKDLRLRQQIVLGF
GTVILLEKLGIDAGGFHINEDYPSFVFLAEIFKLLKKGLTWDKAIEEVRKISLFTTHTPLRVAVNTYPFHMIEEQFLFVK
DVYGIDVKKVLELGTNPEDPSEGFNSTIMSLRLAKYVNAVSKRHQEVSSKMWSFLFKEKENPIDYVTNGVHFPTWICSDL
RRLYEEYLGENFVELHDHKSLWELIRDIPDEELWEYHIRNKERLIEHIKDRARERWVKEKADPSILMAEGLFLDSDVLTV
GFARRMTGYKRPDLIFTDVERLKKIVNDSERPVQIIFAGKAHPADIEGKKIIQRIFNFAKDPEFGGRIAFVEDYDELLAH
YMVRGVDVWLNNPLPPLEACGTSGMKASMNGVLHLSILDGWWIEGYNGKNGWAFGDYEVEGDRNRADAEAIYNILENEVI
PLYYERDERGVPVKWISMMKEAIKSITPNFCSRRMLKDYINKFYSKILKEEG
>Mature_692_residues
MEEEKVKEGLWELAYNLWWTWNPPAKELFRSIDPLLWKETKENPIELLRKTKLLENKLKDEDFISHFKYVYSLYKTYMNR
HSKYEDTYKKPIVFLSPEYGLHHTLLIYAGGLGFLAGDILKESSDLGFPLIGVGFMYPQGYVKQRIRVDGWQEDLDAQNQ
KELMPVKKVLDKEGKWLKCYVYVRDEKVYFGVWEVNVGKTKLYLLDTNVEENTPWNREISSRLYVPDKDLRLRQQIVLGF
GTVILLEKLGIDAGGFHINEDYPSFVFLAEIFKLLKKGLTWDKAIEEVRKISLFTTHTPLRVAVNTYPFHMIEEQFLFVK
DVYGIDVKKVLELGTNPEDPSEGFNSTIMSLRLAKYVNAVSKRHQEVSSKMWSFLFKEKENPIDYVTNGVHFPTWICSDL
RRLYEEYLGENFVELHDHKSLWELIRDIPDEELWEYHIRNKERLIEHIKDRARERWVKEKADPSILMAEGLFLDSDVLTV
GFARRMTGYKRPDLIFTDVERLKKIVNDSERPVQIIFAGKAHPADIEGKKIIQRIFNFAKDPEFGGRIAFVEDYDELLAH
YMVRGVDVWLNNPLPPLEACGTSGMKASMNGVLHLSILDGWWIEGYNGKNGWAFGDYEVEGDRNRADAEAIYNILENEVI
PLYYERDERGVPVKWISMMKEAIKSITPNFCSRRMLKDYINKFYSKILKEEG

Specific function: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties

COG id: COG0058

COG function: function code G; Glucan phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycogen phosphorylase family

Homologues:

Organism=Homo sapiens, GI255653002, Length=586, Percent_Identity=25.5972696245734, Blast_Score=87, Evalue=6e-17,
Organism=Homo sapiens, GI71037379, Length=586, Percent_Identity=25.5972696245734, Blast_Score=87, Evalue=7e-17,
Organism=Homo sapiens, GI257900462, Length=556, Percent_Identity=25, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI5032009, Length=556, Percent_Identity=25, Blast_Score=85, Evalue=2e-16,
Organism=Escherichia coli, GI2367228, Length=624, Percent_Identity=25, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI78706832, Length=456, Percent_Identity=24.5614035087719, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24581010, Length=456, Percent_Identity=24.5614035087719, Blast_Score=75, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHSG_AQUAE (O66932)

Other databases:

- EMBL:   AE000657
- PIR:   H70362
- RefSeq:   NP_213492.1
- ProteinModelPortal:   O66932
- GeneID:   1193381
- GenomeReviews:   AE000657_GR
- KEGG:   aae:aq_717
- NMPDR:   fig|224324.1.peg.507
- HOGENOM:   HBG302557
- OMA:   ISGVDIW
- PhylomeDB:   O66932
- BioCyc:   AAEO224324:AQ_717-MONOMER
- BRENDA:   2.4.1.1
- InterPro:   IPR011834
- InterPro:   IPR000811
- PANTHER:   PTHR11468
- PIRSF:   PIRSF000460
- TIGRFAMs:   TIGR02094

Pfam domain/function: PF00343 Phosphorylase

EC number: =2.4.1.1

Molecular weight: Translated: 81159; Mature: 81159

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS00102 PHOSPHORYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEEKVKEGLWELAYNLWWTWNPPAKELFRSIDPLLWKETKENPIELLRKTKLLENKLKD
CCHHHHHHHHHHHHHHCEECCCCCHHHHHHHHCHHHHHCCCCCHHHHHHHHHHHHHHCCC
EDFISHFKYVYSLYKTYMNRHSKYEDTYKKPIVFLSPEYGLHHTLLIYAGGLGFLAGDIL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCEEEECCCCCCCEEEEEEECCHHHHHHHHH
KESSDLGFPLIGVGFMYPQGYVKQRIRVDGWQEDLDAQNQKELMPVKKVLDKEGKWLKCY
HCCCCCCCCHHHHHHHCCCHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHCCCCCEEEEE
VYVRDEKVYFGVWEVNVGKTKLYLLDTNVEENTPWNREISSRLYVPDKDLRLRQQIVLGF
EEEECCEEEEEEEEEECCCEEEEEEECCCCCCCCCCHHHHCEECCCCHHHHHHHHHHHHH
GTVILLEKLGIDAGGFHINEDYPSFVFLAEIFKLLKKGLTWDKAIEEVRKISLFTTHTPL
HHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEEECCCE
RVAVNTYPFHMIEEQFLFVKDVYGIDVKKVLELGTNPEDPSEGFNSTIMSLRLAKYVNAV
EEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
SKRHQEVSSKMWSFLFKEKENPIDYVTNGVHFPTWICSDLRRLYEEYLGENFVELHDHKS
HHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCHH
LWELIRDIPDEELWEYHIRNKERLIEHIKDRARERWVKEKADPSILMAEGLFLDSDVLTV
HHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEECCCHHHH
GFARRMTGYKRPDLIFTDVERLKKIVNDSERPVQIIFAGKAHPADIEGKKIIQRIFNFAK
HHHHHHCCCCCCCEEHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCC
DPEFGGRIAFVEDYDELLAHYMVRGVDVWLNNPLPPLEACGTSGMKASMNGVLHLSILDG
CCCCCCEEEEHHHHHHHHHHHHHHHHHEEECCCCCCHHHCCCCCCEECCCCEEEEEEECC
WWIEGYNGKNGWAFGDYEVEGDRNRADAEAIYNILENEVIPLYYERDERGVPVKWISMMK
EEEECCCCCCCCEECCEEECCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHH
EAIKSITPNFCSRRMLKDYINKFYSKILKEEG
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEEEKVKEGLWELAYNLWWTWNPPAKELFRSIDPLLWKETKENPIELLRKTKLLENKLKD
CCHHHHHHHHHHHHHHCEECCCCCHHHHHHHHCHHHHHCCCCCHHHHHHHHHHHHHHCCC
EDFISHFKYVYSLYKTYMNRHSKYEDTYKKPIVFLSPEYGLHHTLLIYAGGLGFLAGDIL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCEEEECCCCCCCEEEEEEECCHHHHHHHHH
KESSDLGFPLIGVGFMYPQGYVKQRIRVDGWQEDLDAQNQKELMPVKKVLDKEGKWLKCY
HCCCCCCCCHHHHHHHCCCHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHCCCCCEEEEE
VYVRDEKVYFGVWEVNVGKTKLYLLDTNVEENTPWNREISSRLYVPDKDLRLRQQIVLGF
EEEECCEEEEEEEEEECCCEEEEEEECCCCCCCCCCHHHHCEECCCCHHHHHHHHHHHHH
GTVILLEKLGIDAGGFHINEDYPSFVFLAEIFKLLKKGLTWDKAIEEVRKISLFTTHTPL
HHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEEECCCE
RVAVNTYPFHMIEEQFLFVKDVYGIDVKKVLELGTNPEDPSEGFNSTIMSLRLAKYVNAV
EEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
SKRHQEVSSKMWSFLFKEKENPIDYVTNGVHFPTWICSDLRRLYEEYLGENFVELHDHKS
HHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCHH
LWELIRDIPDEELWEYHIRNKERLIEHIKDRARERWVKEKADPSILMAEGLFLDSDVLTV
HHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEECCCHHHH
GFARRMTGYKRPDLIFTDVERLKKIVNDSERPVQIIFAGKAHPADIEGKKIIQRIFNFAK
HHHHHHCCCCCCCEEHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCC
DPEFGGRIAFVEDYDELLAHYMVRGVDVWLNNPLPPLEACGTSGMKASMNGVLHLSILDG
CCCCCCEEEEHHHHHHHHHHHHHHHHHEEECCCCCCHHHCCCCCCEECCCCEEEEEEECC
WWIEGYNGKNGWAFGDYEVEGDRNRADAEAIYNILENEVIPLYYERDERGVPVKWISMMK
EEEECCCCCCCCEECCEEECCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHH
EAIKSITPNFCSRRMLKDYINKFYSKILKEEG
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320