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The map label for this gene is mpg [H]

Identifier: 15606116

GI number: 15606116

Start: 493455

End: 495950

Strand: Direct

Name: mpg [H]

Synonym: aq_718

Alternate gene names: 15606116

Gene position: 493455-495950 (Clockwise)

Preceding gene: 15606115

Following gene: 15606117

Centisome position: 31.81

GC content: 43.19

Gene sequence:

>2496_bases
ATGAAAGGTGTAATCCTTGCGGGAGGATTTGGAACTAGGATTCAACCCCTTACAAACAGCATTCCCAAACCCATGCTTCC
CGTCGCAAACAGACCCATAATGGAACATGTAGTACACAGGCTAAAGGAGGCGGGAATAGAAGAAATAGTCGTTCTCCTTT
ACTATCAGGCTGAAGTTATAAAGAACTACTTTAAGGACGGAAGTGATTTTGGAGTAAAGATAACCTACGTCCAACCCGAA
GCAGACTACGGAACGGCGGGGGCGGTAAAGCAGGCACAAAATTACCTTAACGAGACATTCATAATAGTAAGCGGTGACGT
AATAACGGACTTCAACCTTTCCGAGTTAATAGCCTTTCATAAAAGCAAGTCTTCAAAGTTTACCTTGGCACTTTACAGTG
TTGAGAATCCCCTTCAGTTTGGAGTTGTGATAACTAACAAAGAAGGGAAAGTTTTGAAATTCCTTGAAAAACCCGGCTGG
GGTGAGGTGTTTAGCGATACCGTAAACACGGGCATATACGTAGTGGAACCCGAAATCCTGAACTACATACCCGAAGACAA
ACCCTTTGACTTTGCCATGGACCTCTTCCCCAAGCTAATGAAGAGCGGGATTGATTTGTGGGCTTTAAAGATGAGGGGAT
ACTGGAGGGACATAGGGAATATAGATTCATACAGGGATGTCCACAAGGATATATTTGCGGGACTCGTAAAGATAAGAATT
CCTGGAAGGATAATTACGACGAAAGAAGCGAGGATTTACGTAGAAGAAGGAACGGAAATTCCCGAAAATGTTAGCTTAAA
GGGAACGGTAATTTTAGGCAAAAACGTAAAAGTAGGGGAGGGTTCAGAACTCAAGAACTGCGTTATAGGAAACAATACGG
TTATAGGGAGAAATGTGAAACTCTTTGATTCCGTTCTGTGGTGGAACGTAAGTATAGACGAAGAGAGTGAAATAAGAAAC
GGAGTTATATGTAACGACGTGAAGATAGGAAAAAGGGTAAAAGCAAAGGAGGGAGTAGTAATAGCCGAAGACTGCGAGGT
TGAGGACGAAGTTCTATTCCTCAAAGACGTGGTTGTATGGCCAGAGAAGGTAATAGAAAAGGGTTCGGTTGTAACAAAGA
ACATCGTATGTGAATCTAAGTGGGAAAAGGGAATATTTAAGGGAAACAAGGTTATCGGAAGGATAAACGTGGAATTGACC
CCGGACAACGCCACAAAACTCGGCATGGCTCTCGGGAGTGTGCTTCCTCCCAAAAGTACGGTAATACTTGCGAGGGATTA
TCACAGGGCTTCAAGGACGATTAAACGCTCCTTTCTCGGAGGCATACTTTCCACAGGTATAAACGTGATAGACCTTCACC
TTTCTCCCCTGCCAGTTATGAGGTTTACCTTAACGGAAGATAAAAAGGCGGTTTGCGGGGTTTACTTTTCCATATCTCAG
GAATTCCCCGGTAGCGTAGAAATATGCGTATTTGACGAAAACGGACTGCCGATAGACACGAATTTCCAGAAGAAGATTGA
AAGGGTGTTCTTCAGGGAAGCTTACAGGTTTGAAACTTTTACCGATTTAGGATTGATAAAGGAAAAGCCTTACTTCTCAG
AAAACTACGTCACTAAACTCCTGAGCAGTATTGACGGAGACAGTATAAAGCTTTCCAGCAATAAAGTCGTTTATGACGCA
CTCCACTCTCCCATTTCTCCCTTTATTTCCGAGGTTTTGGGAAAACTTGAAATAGAAAACGTAATACTGAACGCCCTCTA
CGATGAGAGAAAACTTTCAAGGATATCAACCTACGCGAGCAGTTCCGAAGGAAACGTTTCTAAAGTTCTGAAGGCTTTAT
CCTACGACGTAGGATTTGTAATGGAGCCCAGCGCCACTAAGTTAAAGCTCGTGGACGACAGGGGGAGGACTATAAGCGGT
GATAGGCTCCTTCTGGTAGTCTTAATGCTTCTTGACAAAAGTGCGGAAAAGCAATTGAGGGTTTACCTTCCCGTATGGGC
TCCCGAGGTTCTGGATGCGATTTTAAACAACGTAATCGTTGAAAGGGGAAAGTTTACGAACCTGAGAAAATCCTTTATTG
AAGACTTTTACATGCTGGCGGACACGGACGGGAGTTTTACCTTTACGGAGTTCTCATACTCTCCCGACGCACTTTACGCC
TCCCTCAAGATAATGGAAATGCTAACCAAACTTAAAGTGAAAGTGAGCGAAATTTACGATTCCCTCCCCGAGTATTACTT
CCTGCATGAAGTTGTAAGCTGCAGTTCCGAAAAGAAGGGCACTGTTCTGAGAAAAATATCCGAAATGGCTGAAGGAAAGG
AAGCTTCCTTCATAGAAGGGGTAAAGATATACGAGGATTACGGAAATTGGGTTTTAGTCCTTCCCGATTCTTACAAGGAT
TTAATACACGTGTACGTTCAATCAACGGAGAGGGAAAGAGCGGAAGAACTAATTAAGAATTACATGGAAATAGTGAGGGG
GATTTGCAAAAAATGA

Upstream 100 bases:

>100_bases
TGAAGGAAGCTATAAAAAGCATTACCCCTAACTTTTGCTCCAGAAGGATGTTAAAAGATTACATAAATAAGTTCTATTCA
AAAATTTTAAAGGAGGAGGG

Downstream 100 bases:

>100_bases
AAAAGCTCTTCTTAGTTTTCTGGTGGCATATGCACCAGCCCCTATACAGGGAACCTTACACCGGAGAATACCTCCTCCCG
TGGACTTTCTTCCACGCAGT

Product: mannose-1-phosphate guanyltransferase

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 831; Mature: 831

Protein sequence:

>831_residues
MKGVILAGGFGTRIQPLTNSIPKPMLPVANRPIMEHVVHRLKEAGIEEIVVLLYYQAEVIKNYFKDGSDFGVKITYVQPE
ADYGTAGAVKQAQNYLNETFIIVSGDVITDFNLSELIAFHKSKSSKFTLALYSVENPLQFGVVITNKEGKVLKFLEKPGW
GEVFSDTVNTGIYVVEPEILNYIPEDKPFDFAMDLFPKLMKSGIDLWALKMRGYWRDIGNIDSYRDVHKDIFAGLVKIRI
PGRIITTKEARIYVEEGTEIPENVSLKGTVILGKNVKVGEGSELKNCVIGNNTVIGRNVKLFDSVLWWNVSIDEESEIRN
GVICNDVKIGKRVKAKEGVVIAEDCEVEDEVLFLKDVVVWPEKVIEKGSVVTKNIVCESKWEKGIFKGNKVIGRINVELT
PDNATKLGMALGSVLPPKSTVILARDYHRASRTIKRSFLGGILSTGINVIDLHLSPLPVMRFTLTEDKKAVCGVYFSISQ
EFPGSVEICVFDENGLPIDTNFQKKIERVFFREAYRFETFTDLGLIKEKPYFSENYVTKLLSSIDGDSIKLSSNKVVYDA
LHSPISPFISEVLGKLEIENVILNALYDERKLSRISTYASSSEGNVSKVLKALSYDVGFVMEPSATKLKLVDDRGRTISG
DRLLLVVLMLLDKSAEKQLRVYLPVWAPEVLDAILNNVIVERGKFTNLRKSFIEDFYMLADTDGSFTFTEFSYSPDALYA
SLKIMEMLTKLKVKVSEIYDSLPEYYFLHEVVSCSSEKKGTVLRKISEMAEGKEASFIEGVKIYEDYGNWVLVLPDSYKD
LIHVYVQSTERERAEELIKNYMEIVRGICKK

Sequences:

>Translated_831_residues
MKGVILAGGFGTRIQPLTNSIPKPMLPVANRPIMEHVVHRLKEAGIEEIVVLLYYQAEVIKNYFKDGSDFGVKITYVQPE
ADYGTAGAVKQAQNYLNETFIIVSGDVITDFNLSELIAFHKSKSSKFTLALYSVENPLQFGVVITNKEGKVLKFLEKPGW
GEVFSDTVNTGIYVVEPEILNYIPEDKPFDFAMDLFPKLMKSGIDLWALKMRGYWRDIGNIDSYRDVHKDIFAGLVKIRI
PGRIITTKEARIYVEEGTEIPENVSLKGTVILGKNVKVGEGSELKNCVIGNNTVIGRNVKLFDSVLWWNVSIDEESEIRN
GVICNDVKIGKRVKAKEGVVIAEDCEVEDEVLFLKDVVVWPEKVIEKGSVVTKNIVCESKWEKGIFKGNKVIGRINVELT
PDNATKLGMALGSVLPPKSTVILARDYHRASRTIKRSFLGGILSTGINVIDLHLSPLPVMRFTLTEDKKAVCGVYFSISQ
EFPGSVEICVFDENGLPIDTNFQKKIERVFFREAYRFETFTDLGLIKEKPYFSENYVTKLLSSIDGDSIKLSSNKVVYDA
LHSPISPFISEVLGKLEIENVILNALYDERKLSRISTYASSSEGNVSKVLKALSYDVGFVMEPSATKLKLVDDRGRTISG
DRLLLVVLMLLDKSAEKQLRVYLPVWAPEVLDAILNNVIVERGKFTNLRKSFIEDFYMLADTDGSFTFTEFSYSPDALYA
SLKIMEMLTKLKVKVSEIYDSLPEYYFLHEVVSCSSEKKGTVLRKISEMAEGKEASFIEGVKIYEDYGNWVLVLPDSYKD
LIHVYVQSTERERAEELIKNYMEIVRGICKK
>Mature_831_residues
MKGVILAGGFGTRIQPLTNSIPKPMLPVANRPIMEHVVHRLKEAGIEEIVVLLYYQAEVIKNYFKDGSDFGVKITYVQPE
ADYGTAGAVKQAQNYLNETFIIVSGDVITDFNLSELIAFHKSKSSKFTLALYSVENPLQFGVVITNKEGKVLKFLEKPGW
GEVFSDTVNTGIYVVEPEILNYIPEDKPFDFAMDLFPKLMKSGIDLWALKMRGYWRDIGNIDSYRDVHKDIFAGLVKIRI
PGRIITTKEARIYVEEGTEIPENVSLKGTVILGKNVKVGEGSELKNCVIGNNTVIGRNVKLFDSVLWWNVSIDEESEIRN
GVICNDVKIGKRVKAKEGVVIAEDCEVEDEVLFLKDVVVWPEKVIEKGSVVTKNIVCESKWEKGIFKGNKVIGRINVELT
PDNATKLGMALGSVLPPKSTVILARDYHRASRTIKRSFLGGILSTGINVIDLHLSPLPVMRFTLTEDKKAVCGVYFSISQ
EFPGSVEICVFDENGLPIDTNFQKKIERVFFREAYRFETFTDLGLIKEKPYFSENYVTKLLSSIDGDSIKLSSNKVVYDA
LHSPISPFISEVLGKLEIENVILNALYDERKLSRISTYASSSEGNVSKVLKALSYDVGFVMEPSATKLKLVDDRGRTISG
DRLLLVVLMLLDKSAEKQLRVYLPVWAPEVLDAILNNVIVERGKFTNLRKSFIEDFYMLADTDGSFTFTEFSYSPDALYA
SLKIMEMLTKLKVKVSEIYDSLPEYYFLHEVVSCSSEKKGTVLRKISEMAEGKEASFIEGVKIYEDYGNWVLVLPDSYKD
LIHVYVQSTERERAEELIKNYMEIVRGICKK

Specific function: Catalyzes The Formation Of Dtdp-Glucose, From Dttp And Glucose 1-Phosphate, As Well As Its Pyrophosphorolysis. [C]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=379, Percent_Identity=29.287598944591, Blast_Score=176, Evalue=7e-44,
Organism=Homo sapiens, GI11761619, Length=389, Percent_Identity=29.0488431876607, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI31881779, Length=362, Percent_Identity=25.414364640884, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI45447090, Length=362, Percent_Identity=25.414364640884, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI83267879, Length=421, Percent_Identity=21.1401425178147, Blast_Score=80, Evalue=1e-14,
Organism=Homo sapiens, GI9966779, Length=139, Percent_Identity=27.3381294964029, Blast_Score=70, Evalue=1e-11,
Organism=Homo sapiens, GI262205273, Length=131, Percent_Identity=29.0076335877863, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1790224, Length=234, Percent_Identity=29.4871794871795, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1789837, Length=404, Percent_Identity=24.7524752475248, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1788351, Length=231, Percent_Identity=29.004329004329, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1788355, Length=227, Percent_Identity=24.6696035242291, Blast_Score=70, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI133931050, Length=386, Percent_Identity=32.9015544041451, Blast_Score=189, Evalue=8e-48,
Organism=Caenorhabditis elegans, GI17509979, Length=416, Percent_Identity=25, Blast_Score=110, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17509981, Length=404, Percent_Identity=24.2574257425743, Blast_Score=104, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17535365, Length=389, Percent_Identity=24.9357326478149, Blast_Score=87, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6320148, Length=377, Percent_Identity=30.5039787798408, Blast_Score=170, Evalue=7e-43,
Organism=Saccharomyces cerevisiae, GI6320417, Length=430, Percent_Identity=22.5581395348837, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI21355443, Length=374, Percent_Identity=30.4812834224599, Blast_Score=166, Evalue=5e-41,
Organism=Drosophila melanogaster, GI24644084, Length=374, Percent_Identity=30.4812834224599, Blast_Score=166, Evalue=5e-41,
Organism=Drosophila melanogaster, GI24653912, Length=342, Percent_Identity=24.2690058479532, Blast_Score=99, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 93608; Mature: 93608

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGVILAGGFGTRIQPLTNSIPKPMLPVANRPIMEHVVHRLKEAGIEEIVVLLYYQAEVI
CCCEEEECCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
KNYFKDGSDFGVKITYVQPEADYGTAGAVKQAQNYLNETFIIVSGDVITDFNLSELIAFH
HHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCEEEEEECCEEECCCHHHHHHHH
KSKSSKFTLALYSVENPLQFGVVITNKEGKVLKFLEKPGWGEVFSDTVNTGIYVVEPEIL
CCCCCEEEEEEEEECCCEEEEEEEECCCCCEEHEECCCCCCHHHHHHHCCCEEEECHHHH
NYIPEDKPFDFAMDLFPKLMKSGIDLWALKMRGYWRDIGNIDSYRDVHKDIFAGLVKIRI
HCCCCCCCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHCCCCHHHHHHHHHHHHCEEEEEE
PGRIITTKEARIYVEEGTEIPENVSLKGTVILGKNVKVGEGSELKNCVIGNNTVIGRNVK
CCEEEEECCEEEEEECCCCCCCCCCEEEEEEECCCEECCCCCCCCCEEECCCEEEECCHH
LFDSVLWWNVSIDEESEIRNGVICNDVKIGKRVKAKEGVVIAEDCEVEDEVLFLKDVVVW
HEEEEEEEEEECCCHHHHCCCEEECCCCCCCEEECCCCEEEEECCCCCCCEEEEHHHHHC
PEKVIEKGSVVTKNIVCESKWEKGIFKGNKVIGRINVELTPDNATKLGMALGSVLPPKST
CHHHHCCCCEEEEHEEECCHHHCCCCCCCEEEEEEEEEECCCCHHHHHHHHHCCCCCCCE
VILARDYHRASRTIKRSFLGGILSTGINVIDLHLSPLPVMRFTLTEDKKAVCGVYFSISQ
EEEEECHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEECCCCCCEEEEEEEECC
EFPGSVEICVFDENGLPIDTNFQKKIERVFFREAYRFETFTDLGLIKEKPYFSENYVTKL
CCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCHHHHHHH
LSSIDGDSIKLSSNKVVYDALHSPISPFISEVLGKLEIENVILNALYDERKLSRISTYAS
HHHCCCCEEEECCCCEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SSEGNVSKVLKALSYDVGFVMEPSATKLKLVDDRGRTISGDRLLLVVLMLLDKSAEKQLR
CCCCCHHHHHHHHCCCCCEEECCCCCEEEEEECCCCEECCCHHHHHHHHHHCCCCCCCEE
VYLPVWAPEVLDAILNNVIVERGKFTNLRKSFIEDFYMLADTDGSFTFTEFSYSPDALYA
EEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEEEEECCCCEEEEEECCCCHHHHH
SLKIMEMLTKLKVKVSEIYDSLPEYYFLHEVVSCSSEKKGTVLRKISEMAEGKEASFIEG
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHCC
VKIYEDYGNWVLVLPDSYKDLIHVYVQSTERERAEELIKNYMEIVRGICKK
EEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKGVILAGGFGTRIQPLTNSIPKPMLPVANRPIMEHVVHRLKEAGIEEIVVLLYYQAEVI
CCCEEEECCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
KNYFKDGSDFGVKITYVQPEADYGTAGAVKQAQNYLNETFIIVSGDVITDFNLSELIAFH
HHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCEEEEEECCEEECCCHHHHHHHH
KSKSSKFTLALYSVENPLQFGVVITNKEGKVLKFLEKPGWGEVFSDTVNTGIYVVEPEIL
CCCCCEEEEEEEEECCCEEEEEEEECCCCCEEHEECCCCCCHHHHHHHCCCEEEECHHHH
NYIPEDKPFDFAMDLFPKLMKSGIDLWALKMRGYWRDIGNIDSYRDVHKDIFAGLVKIRI
HCCCCCCCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHCCCCHHHHHHHHHHHHCEEEEEE
PGRIITTKEARIYVEEGTEIPENVSLKGTVILGKNVKVGEGSELKNCVIGNNTVIGRNVK
CCEEEEECCEEEEEECCCCCCCCCCEEEEEEECCCEECCCCCCCCCEEECCCEEEECCHH
LFDSVLWWNVSIDEESEIRNGVICNDVKIGKRVKAKEGVVIAEDCEVEDEVLFLKDVVVW
HEEEEEEEEEECCCHHHHCCCEEECCCCCCCEEECCCCEEEEECCCCCCCEEEEHHHHHC
PEKVIEKGSVVTKNIVCESKWEKGIFKGNKVIGRINVELTPDNATKLGMALGSVLPPKST
CHHHHCCCCEEEEHEEECCHHHCCCCCCCEEEEEEEEEECCCCHHHHHHHHHCCCCCCCE
VILARDYHRASRTIKRSFLGGILSTGINVIDLHLSPLPVMRFTLTEDKKAVCGVYFSISQ
EEEEECHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEECCCCCCEEEEEEEECC
EFPGSVEICVFDENGLPIDTNFQKKIERVFFREAYRFETFTDLGLIKEKPYFSENYVTKL
CCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCHHHHHHH
LSSIDGDSIKLSSNKVVYDALHSPISPFISEVLGKLEIENVILNALYDERKLSRISTYAS
HHHCCCCEEEECCCCEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SSEGNVSKVLKALSYDVGFVMEPSATKLKLVDDRGRTISGDRLLLVVLMLLDKSAEKQLR
CCCCCHHHHHHHHCCCCCEEECCCCCEEEEEECCCCEECCCHHHHHHHHHHCCCCCCCEE
VYLPVWAPEVLDAILNNVIVERGKFTNLRKSFIEDFYMLADTDGSFTFTEFSYSPDALYA
EEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEEEEECCCCEEEEEECCCCHHHHH
SLKIMEMLTKLKVKVSEIYDSLPEYYFLHEVVSCSSEKKGTVLRKISEMAEGKEASFIEG
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHCC
VKIYEDYGNWVLVLPDSYKDLIHVYVQSTERERAEELIKNYMEIVRGICKK
EEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]