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The map label for this gene is pfpI [H]

Identifier: 15606052

GI number: 15606052

Start: 419585

End: 420088

Strand: Direct

Name: pfpI [H]

Synonym: aq_618

Alternate gene names: 15606052

Gene position: 419585-420088 (Clockwise)

Preceding gene: 15606051

Following gene: 15606053

Centisome position: 27.05

GC content: 45.04

Gene sequence:

>504_bases
ATGAGAAAAGTACTCATCTTCTTAGAAGAACTCGTTGAAGACGTTGAGTTTATATACCCGTACCTCAGGTTTAAGGAGGA
GGGGTTTGAAGTAGTATCCGCTGCCCCGAAGCTCGGAGAGTATAAAGGCAAAAAGGGAATGACTTTCAGACCAGATAAGA
CCATAAAAGACGTTTACCACCAGGAATTTGACTGCGTATTTATACCGGGGGGATACGCTCCCGACAGACTGAGGAGGTAT
CCCGAAGTTCTACACATAGTTAAAAAACACTACGACAGCGGAAAGCTCGTTTGTGCGGTTTGCCACGGTCCGTGGGTTCT
TATCTCCGCAAAAGTTGTTAAGGGAAAAAAGGTAACGGGATTTTTCGCAATAAAAGATGACCTTATAAACGCAGGTGCGA
ATTACACGGGGAAACCCGTGGAAGTTGACGGCAACCTTATTACCGCAACCGATCCCAAGTCCATGCTTGAGATGATGAAG
GTGATTATATCGAGGCTAAAGTAA

Upstream 100 bases:

>100_bases
GCAAGTGTGGCTAAACAAATAAACGGAGACAGAAAACTCTACGCGGAAAGCATACCCGTAACGAGAGAAGTCCTGAGGAC
GATGATTTAAAATTAAGTTT

Downstream 100 bases:

>100_bases
TGAAGAAATTTTTAATAATCCTCTTATCCTTCGTTCTTTTCGTATTCCCTGAGGATCTTATTCTCGTGAGCATTTATCCC
TTTTACGACGTTGTAAAAGA

Product: protease I

Products: NA

Alternate protein names: Intracellular protease I [H]

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MRKVLIFLEELVEDVEFIYPYLRFKEEGFEVVSAAPKLGEYKGKKGMTFRPDKTIKDVYHQEFDCVFIPGGYAPDRLRRY
PEVLHIVKKHYDSGKLVCAVCHGPWVLISAKVVKGKKVTGFFAIKDDLINAGANYTGKPVEVDGNLITATDPKSMLEMMK
VIISRLK

Sequences:

>Translated_167_residues
MRKVLIFLEELVEDVEFIYPYLRFKEEGFEVVSAAPKLGEYKGKKGMTFRPDKTIKDVYHQEFDCVFIPGGYAPDRLRRY
PEVLHIVKKHYDSGKLVCAVCHGPWVLISAKVVKGKKVTGFFAIKDDLINAGANYTGKPVEVDGNLITATDPKSMLEMMK
VIISRLK
>Mature_167_residues
MRKVLIFLEELVEDVEFIYPYLRFKEEGFEVVSAAPKLGEYKGKKGMTFRPDKTIKDVYHQEFDCVFIPGGYAPDRLRRY
PEVLHIVKKHYDSGKLVCAVCHGPWVLISAKVVKGKKVTGFFAIKDDLINAGANYTGKPVEVDGNLITATDPKSMLEMMK
VIISRLK

Specific function: Unknown

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PfpI endopeptidase domain [H]

Homologues:

Organism=Escherichia coli, GI87082219, Length=157, Percent_Identity=37.5796178343949, Blast_Score=104, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17558714, Length=167, Percent_Identity=29.940119760479, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28571932, Length=158, Percent_Identity=29.1139240506329, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006286
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 18974; Mature: 18974

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKVLIFLEELVEDVEFIYPYLRFKEEGFEVVSAAPKLGEYKGKKGMTFRPDKTIKDVYH
CCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHCCCCCCCCCCCCCHHHHHHHH
QEFDCVFIPGGYAPDRLRRYPEVLHIVKKHYDSGKLVCAVCHGPWVLISAKVVKGKKVTG
CCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEEEECCCEEEE
FFAIKDDLINAGANYTGKPVEVDGNLITATDPKSMLEMMKVIISRLK
EEEEHHHHHHCCCCCCCCEEEECCCEEEECCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRKVLIFLEELVEDVEFIYPYLRFKEEGFEVVSAAPKLGEYKGKKGMTFRPDKTIKDVYH
CCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHCCCCCCCCCCCCCHHHHHHHH
QEFDCVFIPGGYAPDRLRRYPEVLHIVKKHYDSGKLVCAVCHGPWVLISAKVVKGKKVTG
CCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEEEECCCEEEE
FFAIKDDLINAGANYTGKPVEVDGNLITATDPKSMLEMMKVIISRLK
EEEEHHHHHHCCCCCCCCEEEECCCEEEECCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]