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The map label for this gene is napA1 [H]

Identifier: 15605914

GI number: 15605914

Start: 284327

End: 285490

Strand: Direct

Name: napA1 [H]

Synonym: aq_415

Alternate gene names: 15605914

Gene position: 284327-285490 (Clockwise)

Preceding gene: 15605913

Following gene: 15605915

Centisome position: 18.33

GC content: 43.9

Gene sequence:

>1164_bases
TTGTGCCGGAGGTTGTCCTTGAGCAGTGAACTCTTCCTCATAATCGTATTCCTTTCCGCCTTCCTTGCACCACTTTTTTC
AAGAATCCTTAGAATGCCCGTACCCGTAGGTGAACTCATTTTCGGTATCTTAATCGGAAATTTCTTCGTAGGCATTCAGG
TTCCCGAAATACTGAACTTCCTGTCAGACTTTGGTTTCCTCCTCCTTATGTTTCTCGCGGGACTAGAGCTCGATTTCAAC
CTAATAGAAAAGGCGGACAAGAAACAGAACGCCGTTTACATCTCGTACGTCCTCCTCATATTCTTGAGTGCTTTTGTCTT
TGGAATTTTGCTGGGAATAGGAACAGCTCCCGCTATAATTCTTTCCCTAATTTCCCTCGGTCTTATGGTTGCAACCCTGA
AGGACATGAGCGTTCTGGAAGAGCCCTTCGCAAAGAAAGTTTTACTGATAGGTGTCTTCGGGGAAATTATCAGTCTCCTT
GCTTTGACCTTAATGGAAAAGCTCCTACACTTCCACGGTTTTGTAAGCTTAATAAAGGAACTCGGAGTAATTTTTGTCTT
TTTCTTCAGTTTCTTTTTAGGATTTTACTTAACTAGACTCCTCGTCTGGTGGTATCCCGAGATAGTGAACAGACTCACCT
ACGAAGAGGATCCGAGCGCTTTAGGGATAAGGCTCAGTTTATTTTTGATGTTTACTTCCTCAATCTTTGCAAAGCTTGCG
GGAATAGAGAGCGTTCTGGGAGCCTTCATGGCGGGAGTGGTGTTTTCCTACTTCATAAGGGAGAAAAAGGATCTTGAAGA
AAAGCTCAGTTCAATAGGTTACGGGTTTTTAATTCCCATCTTTTTCATAAAGACCGGAATGGGAATGGAAGTTGCAGGTT
TAAACCTCGCTATCCTCTTTAAGGTGTTCATATTTCTCGCCTTTATGCTCTTTGTAAGGTTAATTCCCTCCTTCGTCCTT
CTCCTCGCCGGATTTTCCCTGAAAGACTCTTTTACGGCGGGTCTTCTCTTGTCTTACCCTTTCACTCTTATGGTTGCGGG
AATAGAGATAGCGAGGAGGGGCGGAGCTCTGGACGAGGAAACAGCCCTAGCACTCTTTTTAACCGCAGCTTTCTCTTCTC
TGGTATTCCCGTGGAGTGCAAAAATAATTCTTTCTAGAAGATGA

Upstream 100 bases:

>100_bases
AATCTCCTCCTAATAGGATACAAGGTGGGAAGAACTACGAAATTATTCTCACCTTACTCACCTCACCTCATAGCGAGAAA
GAGTAAACTCAGTACTCTCC

Downstream 100 bases:

>100_bases
ACTATATTCTGTAATTATGGAATTTGTAACGAATTACACGCTAGAAGAGCTTAAAAAACGCTTCACCGAACTGGGACTCG
AACCTTACAGGGCAAAGCAG

Product: Na(+)/H(+) antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MCRRLSLSSELFLIIVFLSAFLAPLFSRILRMPVPVGELIFGILIGNFFVGIQVPEILNFLSDFGFLLLMFLAGLELDFN
LIEKADKKQNAVYISYVLLIFLSAFVFGILLGIGTAPAIILSLISLGLMVATLKDMSVLEEPFAKKVLLIGVFGEIISLL
ALTLMEKLLHFHGFVSLIKELGVIFVFFFSFFLGFYLTRLLVWWYPEIVNRLTYEEDPSALGIRLSLFLMFTSSIFAKLA
GIESVLGAFMAGVVFSYFIREKKDLEEKLSSIGYGFLIPIFFIKTGMGMEVAGLNLAILFKVFIFLAFMLFVRLIPSFVL
LLAGFSLKDSFTAGLLLSYPFTLMVAGIEIARRGGALDEETALALFLTAAFSSLVFPWSAKIILSRR

Sequences:

>Translated_387_residues
MCRRLSLSSELFLIIVFLSAFLAPLFSRILRMPVPVGELIFGILIGNFFVGIQVPEILNFLSDFGFLLLMFLAGLELDFN
LIEKADKKQNAVYISYVLLIFLSAFVFGILLGIGTAPAIILSLISLGLMVATLKDMSVLEEPFAKKVLLIGVFGEIISLL
ALTLMEKLLHFHGFVSLIKELGVIFVFFFSFFLGFYLTRLLVWWYPEIVNRLTYEEDPSALGIRLSLFLMFTSSIFAKLA
GIESVLGAFMAGVVFSYFIREKKDLEEKLSSIGYGFLIPIFFIKTGMGMEVAGLNLAILFKVFIFLAFMLFVRLIPSFVL
LLAGFSLKDSFTAGLLLSYPFTLMVAGIEIARRGGALDEETALALFLTAAFSSLVFPWSAKIILSRR
>Mature_387_residues
MCRRLSLSSELFLIIVFLSAFLAPLFSRILRMPVPVGELIFGILIGNFFVGIQVPEILNFLSDFGFLLLMFLAGLELDFN
LIEKADKKQNAVYISYVLLIFLSAFVFGILLGIGTAPAIILSLISLGLMVATLKDMSVLEEPFAKKVLLIGVFGEIISLL
ALTLMEKLLHFHGFVSLIKELGVIFVFFFSFFLGFYLTRLLVWWYPEIVNRLTYEEDPSALGIRLSLFLMFTSSIFAKLA
GIESVLGAFMAGVVFSYFIREKKDLEEKLSSIGYGFLIPIFFIKTGMGMEVAGLNLAILFKVFIFLAFMLFVRLIPSFVL
LLAGFSLKDSFTAGLLLSYPFTLMVAGIEIARRGGALDEETALALFLTAAFSSLVFPWSAKIILSRR

Specific function: Probable Na(+)/H(+) antiporter [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322367, Length=399, Percent_Identity=24.5614035087719, Blast_Score=76, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF00999 Na_H_Exchanger; PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 43150; Mature: 43150

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCRRLSLSSELFLIIVFLSAFLAPLFSRILRMPVPVGELIFGILIGNFFVGIQVPEILNF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHH
LSDFGFLLLMFLAGLELDFNLIEKADKKQNAVYISYVLLIFLSAFVFGILLGIGTAPAII
HHHHHHHHHHHHHCCCCCHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
LSLISLGLMVATLKDMSVLEEPFAKKVLLIGVFGEIISLLALTLMEKLLHFHGFVSLIKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGVIFVFFFSFFLGFYLTRLLVWWYPEIVNRLTYEEDPSALGIRLSLFLMFTSSIFAKLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
GIESVLGAFMAGVVFSYFIREKKDLEEKLSSIGYGFLIPIFFIKTGMGMEVAGLNLAILF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEECCCHHHHHH
KVFIFLAFMLFVRLIPSFVLLLAGFSLKDSFTAGLLLSYPFTLMVAGIEIARRGGALDEE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
TALALFLTAAFSSLVFPWSAKIILSRR
HHHHHHHHHHHHHHHCCCHHHEEEECC
>Mature Secondary Structure
MCRRLSLSSELFLIIVFLSAFLAPLFSRILRMPVPVGELIFGILIGNFFVGIQVPEILNF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHH
LSDFGFLLLMFLAGLELDFNLIEKADKKQNAVYISYVLLIFLSAFVFGILLGIGTAPAII
HHHHHHHHHHHHHCCCCCHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
LSLISLGLMVATLKDMSVLEEPFAKKVLLIGVFGEIISLLALTLMEKLLHFHGFVSLIKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGVIFVFFFSFFLGFYLTRLLVWWYPEIVNRLTYEEDPSALGIRLSLFLMFTSSIFAKLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
GIESVLGAFMAGVVFSYFIREKKDLEEKLSSIGYGFLIPIFFIKTGMGMEVAGLNLAILF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEECCCHHHHHH
KVFIFLAFMLFVRLIPSFVLLLAGFSLKDSFTAGLLLSYPFTLMVAGIEIARRGGALDEE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
TALALFLTAAFSSLVFPWSAKIILSRR
HHHHHHHHHHHHHHHCCCHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]