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The map label for this gene is ctaA [H]

Identifier: 15605726

GI number: 15605726

Start: 92881

End: 93771

Strand: Direct

Name: ctaA [H]

Synonym: aq_153

Alternate gene names: 15605726

Gene position: 92881-93771 (Clockwise)

Preceding gene: 15605725

Following gene: 15605727

Centisome position: 5.99

GC content: 45.01

Gene sequence:

>891_bases
ATGAACACCAACCTCAAAAGTAGTCCCCTGAAGACGTTAGTTCTCGCCTCGGTTGTCTTGACTTACGTTTTGATGGTATT
CGGAGGTATAGTTACCTCTACGGGTTCAGGGCTCGGATGTCCCGACTGGCCCCTGTGTCACGGACAACTCCTTCCTTTTC
AGTTAAAGGAACAAATTCCCACACCTCCCGCACCCGTGGTAGCTCCAACTCCCCTCCAGCCCTGGATTGAACAAACACAC
AGGATACTCGGAGGAATAACTGGCATAGTTCTGCTCGCAACACTCTTTTACGCCTTCAAAAGGGGAACTTCTTTCGTTAA
AAAAGCCCTCGTTTTTATATTCATAGCTCTGATACTGGAAGCCCTTCTCGGCATGAGGGTTGTAATAACGGAGGCACCGC
TTCTCAGAGAACTACTCCACTATGTCTACACGAGCGCTCACCTCATACTTTCGGTGTTTATACTTTCAACGATAACCATA
ACTTACTACTACGTTAAGTTTTTTGGGGAAAGGCCTAAGGAGTACATCCCTTATGCAGATGCCCTCTACGTTGCAACTAT
GTTCCAGATACTGCTCGGTATATTCGTGAGGTACGTAAAAGCCCTTGAGTACAATCAGTTTGTTTACTACCTTCACATAA
CTTACGCGGGTTTCCTCGTTATACTCTCCCTCTTCATAATGTTTAAGGAGTTCAACAAGTACTCTTTAATAACGTTTCTC
TTAATGACCGCTCAGATACTCGCAGGTGTCGCCACCGTGATTTCAGGGTTCTTTTTACCGTACCTCTTTCTTCACATAGC
AATAGGATTCTTTATAGTCCTTTGGGTATCCTACCTTGTAGCACCTTCCGTTTTAAAGACTTATACTGAGTTTAGAGGAG
AGCTGGCATGA

Upstream 100 bases:

>100_bases
AACAGGGAGTACTTTTTAAAGAGGCTTGAACGTGCAAGGGAAACAAATCCCATAAAAGAGTCCGTTGAAATGTTAAAAGA
AAGATTAAAAGGAGGAGAGC

Downstream 100 bases:

>100_bases
GTGAAAGGGTAGAGGCGGGACAGAACGTGATAAAGGAGTATTTGGTTCTCACAAAACCGGGAATAGTTTCCTTAGTTCTT
ATTACCACTCTCGGCGGAAT

Product: heme O oxygenase

Products: biliverdin; Fe2+; CO; A; H2O

Alternate protein names: HAS; Cytochrome aa3-controlling protein [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MNTNLKSSPLKTLVLASVVLTYVLMVFGGIVTSTGSGLGCPDWPLCHGQLLPFQLKEQIPTPPAPVVAPTPLQPWIEQTH
RILGGITGIVLLATLFYAFKRGTSFVKKALVFIFIALILEALLGMRVVITEAPLLRELLHYVYTSAHLILSVFILSTITI
TYYYVKFFGERPKEYIPYADALYVATMFQILLGIFVRYVKALEYNQFVYYLHITYAGFLVILSLFIMFKEFNKYSLITFL
LMTAQILAGVATVISGFFLPYLFLHIAIGFFIVLWVSYLVAPSVLKTYTEFRGELA

Sequences:

>Translated_296_residues
MNTNLKSSPLKTLVLASVVLTYVLMVFGGIVTSTGSGLGCPDWPLCHGQLLPFQLKEQIPTPPAPVVAPTPLQPWIEQTH
RILGGITGIVLLATLFYAFKRGTSFVKKALVFIFIALILEALLGMRVVITEAPLLRELLHYVYTSAHLILSVFILSTITI
TYYYVKFFGERPKEYIPYADALYVATMFQILLGIFVRYVKALEYNQFVYYLHITYAGFLVILSLFIMFKEFNKYSLITFL
LMTAQILAGVATVISGFFLPYLFLHIAIGFFIVLWVSYLVAPSVLKTYTEFRGELA
>Mature_296_residues
MNTNLKSSPLKTLVLASVVLTYVLMVFGGIVTSTGSGLGCPDWPLCHGQLLPFQLKEQIPTPPAPVVAPTPLQPWIEQTH
RILGGITGIVLLATLFYAFKRGTSFVKKALVFIFIALILEALLGMRVVITEAPLLRELLHYVYTSAHLILSVFILSTITI
TYYYVKFFGERPKEYIPYADALYVATMFQILLGIFVRYVKALEYNQFVYYLHITYAGFLVILSLFIMFKEFNKYSLITFL
LMTAQILAGVATVISGFFLPYLFLHIAIGFFIVLWVSYLVAPSVLKTYTEFRGELA

Specific function: Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group [H]

COG id: COG1612

COG function: function code O; Uncharacterized protein required for cytochrome oxidase assembly

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX15/CtaA family. Type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003780 [H]

Pfam domain/function: PF02628 COX15-CtaA [H]

EC number: 1.14.99.3

Molecular weight: Translated: 33344; Mature: 33344

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTNLKSSPLKTLVLASVVLTYVLMVFGGIVTSTGSGLGCPDWPLCHGQLLPFQLKEQIP
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCCC
TPPAPVVAPTPLQPWIEQTHRILGGITGIVLLATLFYAFKRGTSFVKKALVFIFIALILE
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLGMRVVITEAPLLRELLHYVYTSAHLILSVFILSTITITYYYVKFFGERPKEYIPYAD
HHHCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHH
ALYVATMFQILLGIFVRYVKALEYNQFVYYLHITYAGFLVILSLFIMFKEFNKYSLITFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
LMTAQILAGVATVISGFFLPYLFLHIAIGFFIVLWVSYLVAPSVLKTYTEFRGELA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNTNLKSSPLKTLVLASVVLTYVLMVFGGIVTSTGSGLGCPDWPLCHGQLLPFQLKEQIP
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCCC
TPPAPVVAPTPLQPWIEQTHRILGGITGIVLLATLFYAFKRGTSFVKKALVFIFIALILE
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLGMRVVITEAPLLRELLHYVYTSAHLILSVFILSTITITYYYVKFFGERPKEYIPYAD
HHHCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHH
ALYVATMFQILLGIFVRYVKALEYNQFVYYLHITYAGFLVILSLFIMFKEFNKYSLITFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
LMTAQILAGVATVISGFFLPYLFLHIAIGFFIVLWVSYLVAPSVLKTYTEFRGELA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: heme; AH2; O2

Specific reaction: heme + 3 AH2 + 3 O2 = biliverdin + Fe2+ + CO + 3 A + 3 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA