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The map label for this gene is ribD [H]

Identifier: 15602614

GI number: 15602614

Start: 882687

End: 883817

Strand: Reverse

Name: ribD [H]

Synonym: PM0749

Alternate gene names: 15602614

Gene position: 883817-882687 (Counterclockwise)

Preceding gene: 15602615

Following gene: 15602613

Centisome position: 39.15

GC content: 46.07

Gene sequence:

>1131_bases
ATGATGACATTTACGGCACAAGATGTAGTGTACATGCAAATGGCATTAGAGTTAGCGGAGAAAGGGCAATTTACTACTAC
ACCGAACCCCTCAGTGGGTTGCGTATTAGTGAAAGACGGTATTATTGTTGGACGTGGCTTTCATGTTAAAGCAGGCGAGG
CGCATGCTGAAGTCATGGCATTGCGAGAGGCGGGAGAAAATGCACGAGGTGCAACCGCTTATGTGACATTAGAACCGTGC
TCACATTTTGGACGTACTCCCCCTTGTGCCCAAGGTTTGATCGATGCTGGTGTAGTGAAAGTCGTGAGTGCGATGTGCGA
TCCCAATCCGCAAGTGGCAGGTCGAGGATTAAGCATGTTATCTGATGCGGGGATCGAAAGTGCGGTCGGTTTATTAGCTG
AAAAGGCGGAGTGGCTTAATCGTGGTTTTCTTAAACGTATGCGTACTGGCAGACCTTATGTACAACTAAAAATGGCTATG
AGTTTAGATGGAAGAACCGCGATGGCAAACGGGGAAAGTAAGTGGATTACCGGTGAGCTTGCTCGTGCAGATGTGCAAGC
AGAACGAGCCAAAGCCTCAGCGATTTTATCCACCAGTGCAACGGTGTTAGCTGATGATCCCTTATTAAATGTACGCTGGC
AACAATTACCTGACAAGGTGAAAGCCGATTATACACAAGCGCAGCTACGTCAACCTGTGCGAGTGATTTTAGATTCTCAA
CATCGAGTTCAACCCTCACACCGACTTTTCAGTCTGTCTTCGCCAGTGTGGTTAGTGAGTCAAACTGCGCGTTCGTTACT
TGAGTTTCCTGCACATTGCGAACAAATACAGCTTTCCGCTTCTACCAACGCTTTAGCTGATTTAATGGCAGAATTAGGAC
AACGTCAAATCAATACGCTTTGGATTGAAGCCGGTGCGACATTGGCTGGTGCATTAATTGAGGCAAAATTAGTGGATGAA
TTGATCATTTACATTGCACCGAAATTATTAGGTGATGCCGCACGAGGATTATGTAAATTACCTCATTTAAGCACCTTGGC
TGAGGCAAGTTTATGGCAATTGCATTCCATTGAGAAACTCGGCGATGATCTGAAAACGATTTACCACCCACGAATTACGG
AGCCAACATGA

Upstream 100 bases:

>100_bases
AAAAATTGGATAAAGTGGCTTATATTCGTTTTGCGTCAGTGTATTTAAGTTTCGATGATATTAACCAATTTAGTAAAGAA
ATTGAAAAATTAAGGGATTA

Downstream 100 bases:

>100_bases
TCAAAAAACTTTTTCATTCAGTGATGATTGGGTTAGTGTGTGCCGCAGTGATTCTGGTATTTTCACACGTTAACCAATTT
AGCTTACTCAAAGCACCAGA

Product: hypothetical protein

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MMTFTAQDVVYMQMALELAEKGQFTTTPNPSVGCVLVKDGIIVGRGFHVKAGEAHAEVMALREAGENARGATAYVTLEPC
SHFGRTPPCAQGLIDAGVVKVVSAMCDPNPQVAGRGLSMLSDAGIESAVGLLAEKAEWLNRGFLKRMRTGRPYVQLKMAM
SLDGRTAMANGESKWITGELARADVQAERAKASAILSTSATVLADDPLLNVRWQQLPDKVKADYTQAQLRQPVRVILDSQ
HRVQPSHRLFSLSSPVWLVSQTARSLLEFPAHCEQIQLSASTNALADLMAELGQRQINTLWIEAGATLAGALIEAKLVDE
LIIYIAPKLLGDAARGLCKLPHLSTLAEASLWQLHSIEKLGDDLKTIYHPRITEPT

Sequences:

>Translated_376_residues
MMTFTAQDVVYMQMALELAEKGQFTTTPNPSVGCVLVKDGIIVGRGFHVKAGEAHAEVMALREAGENARGATAYVTLEPC
SHFGRTPPCAQGLIDAGVVKVVSAMCDPNPQVAGRGLSMLSDAGIESAVGLLAEKAEWLNRGFLKRMRTGRPYVQLKMAM
SLDGRTAMANGESKWITGELARADVQAERAKASAILSTSATVLADDPLLNVRWQQLPDKVKADYTQAQLRQPVRVILDSQ
HRVQPSHRLFSLSSPVWLVSQTARSLLEFPAHCEQIQLSASTNALADLMAELGQRQINTLWIEAGATLAGALIEAKLVDE
LIIYIAPKLLGDAARGLCKLPHLSTLAEASLWQLHSIEKLGDDLKTIYHPRITEPT
>Mature_376_residues
MMTFTAQDVVYMQMALELAEKGQFTTTPNPSVGCVLVKDGIIVGRGFHVKAGEAHAEVMALREAGENARGATAYVTLEPC
SHFGRTPPCAQGLIDAGVVKVVSAMCDPNPQVAGRGLSMLSDAGIESAVGLLAEKAEWLNRGFLKRMRTGRPYVQLKMAM
SLDGRTAMANGESKWITGELARADVQAERAKASAILSTSATVLADDPLLNVRWQQLPDKVKADYTQAQLRQPVRVILDSQ
HRVQPSHRLFSLSSPVWLVSQTARSLLEFPAHCEQIQLSASTNALADLMAELGQRQINTLWIEAGATLAGALIEAKLVDE
LIIYIAPKLLGDAARGLCKLPHLSTLAEASLWQLHSIEKLGDDLKTIYHPRITEPT

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=367, Percent_Identity=58.0381471389646, Blast_Score=423, Evalue=1e-120,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 40753; Mature: 40753

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTFTAQDVVYMQMALELAEKGQFTTTPNPSVGCVLVKDGIIVGRGFHVKAGEAHAEVMA
CCEECHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCEEEECCEEEECCCHHHHHHH
LREAGENARGATAYVTLEPCSHFGRTPPCAQGLIDAGVVKVVSAMCDPNPQVAGRGLSML
HHHCCCCCCCCEEEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHH
SDAGIESAVGLLAEKAEWLNRGFLKRMRTGRPYVQLKMAMSLDGRTAMANGESKWITGEL
HHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEECCCCCCEEEHHH
ARADVQAERAKASAILSTSATVLADDPLLNVRWQQLPDKVKADYTQAQLRQPVRVILDSQ
HHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCC
HRVQPSHRLFSLSSPVWLVSQTARSLLEFPAHCEQIQLSASTNALADLMAELGQRQINTL
CCCCCCHHEEECCCCHHHHHHHHHHHHHCCCHHHHEEECCCHHHHHHHHHHHCHHHHHEE
WIEAGATLAGALIEAKLVDELIIYIAPKLLGDAARGLCKLPHLSTLAEASLWQLHSIEKL
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
GDDLKTIYHPRITEPT
HHHHHHHHCCCCCCCC
>Mature Secondary Structure
MMTFTAQDVVYMQMALELAEKGQFTTTPNPSVGCVLVKDGIIVGRGFHVKAGEAHAEVMA
CCEECHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCEEEECCEEEECCCHHHHHHH
LREAGENARGATAYVTLEPCSHFGRTPPCAQGLIDAGVVKVVSAMCDPNPQVAGRGLSML
HHHCCCCCCCCEEEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHH
SDAGIESAVGLLAEKAEWLNRGFLKRMRTGRPYVQLKMAMSLDGRTAMANGESKWITGEL
HHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEECCCCCCEEEHHH
ARADVQAERAKASAILSTSATVLADDPLLNVRWQQLPDKVKADYTQAQLRQPVRVILDSQ
HHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCC
HRVQPSHRLFSLSSPVWLVSQTARSLLEFPAHCEQIQLSASTNALADLMAELGQRQINTL
CCCCCCHHEEECCCCHHHHHHHHHHHHHCCCHHHHEEECCCHHHHHHHHHHHCHHHHHEE
WIEAGATLAGALIEAKLVDELIIYIAPKLLGDAARGLCKLPHLSTLAEASLWQLHSIEKL
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
GDDLKTIYHPRITEPT
HHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]