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The map label for this gene is nrdR

Identifier: 15602615

GI number: 15602615

Start: 883817

End: 884266

Strand: Reverse

Name: nrdR

Synonym: PM0750

Alternate gene names: 15602615

Gene position: 884266-883817 (Counterclockwise)

Preceding gene: 15602616

Following gene: 15602614

Centisome position: 39.17

GC content: 39.33

Gene sequence:

>450_bases
ATGCATTGCCCTTTTTGCTCTACGGAAGAAACGAAAGTGATCGATAGCCGTTTGGTGTCAGAAGGCTATCAAGTAAGACG
TCGTCGTGAATGTGGAAATTGCCATGAGCGCTTTACCACCTTTGAAACGGCAGAGTTAATTATTCCCAAAGTGATTAAAA
ATGATGGCACACGTGAACCCTTTAATGAGGAAAAATTACGTCGTGGCATTCAGCATGCGTTAGAAAAACGCCCGGTAAGT
GAGAACGATGTGGAAAAGGCGATTAGCTATATTATTCATCGTTTACGCAGTACGGGTGAACGTGAAGTACCAAGCAAATT
AGTTGGGACGTTAGTCATGGAAGAGCTGAAAAAATTGGATAAAGTGGCTTATATTCGTTTTGCGTCAGTGTATTTAAGTT
TCGATGATATTAACCAATTTAGTAAAGAAATTGAAAAATTAAGGGATTAA

Upstream 100 bases:

>100_bases
CTTGCCGTAAATAACAAAATAATTCGTCGTCAATATTCAGAATCTTTGTTAAGATGAGATGCATTATGATGAATGACTTT
ACGAAGGATAAGGAAACGTT

Downstream 100 bases:

>100_bases
TGATGACATTTACGGCACAAGATGTAGTGTACATGCAAATGGCATTAGAGTTAGCGGAGAAAGGGCAATTTACTACTACA
CCGAACCCCTCAGTGGGTTG

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MHCPFCSTEETKVIDSRLVSEGYQVRRRRECGNCHERFTTFETAELIIPKVIKNDGTREPFNEEKLRRGIQHALEKRPVS
ENDVEKAISYIIHRLRSTGEREVPSKLVGTLVMEELKKLDKVAYIRFASVYLSFDDINQFSKEIEKLRD

Sequences:

>Translated_149_residues
MHCPFCSTEETKVIDSRLVSEGYQVRRRRECGNCHERFTTFETAELIIPKVIKNDGTREPFNEEKLRRGIQHALEKRPVS
ENDVEKAISYIIHRLRSTGEREVPSKLVGTLVMEELKKLDKVAYIRFASVYLSFDDINQFSKEIEKLRD
>Mature_149_residues
MHCPFCSTEETKVIDSRLVSEGYQVRRRRECGNCHERFTTFETAELIIPKVIKNDGTREPFNEEKLRRGIQHALEKRPVS
ENDVEKAISYIIHRLRSTGEREVPSKLVGTLVMEELKKLDKVAYIRFASVYLSFDDINQFSKEIEKLRD

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=149, Percent_Identity=69.1275167785235, Blast_Score=217, Evalue=3e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_PASMU (Q9CMR2)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245687.1
- GeneID:   1244097
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0750
- NMPDR:   fig|272843.1.peg.750
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- ProtClustDB:   PRK00464
- BioCyc:   PMUL272843:PM0750-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17462; Mature: 17462

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHCPFCSTEETKVIDSRLVSEGYQVRRRRECGNCHERFTTFETAELIIPKVIKNDGTREP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
FNEEKLRRGIQHALEKRPVSENDVEKAISYIIHRLRSTGEREVPSKLVGTLVMEELKKLD
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
KVAYIRFASVYLSFDDINQFSKEIEKLRD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHCPFCSTEETKVIDSRLVSEGYQVRRRRECGNCHERFTTFETAELIIPKVIKNDGTREP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
FNEEKLRRGIQHALEKRPVSENDVEKAISYIIHRLRSTGEREVPSKLVGTLVMEELKKLD
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
KVAYIRFASVYLSFDDINQFSKEIEKLRD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100