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The map label for this gene is degS [H]

Identifier: 15602613

GI number: 15602613

Start: 881662

End: 882690

Strand: Reverse

Name: degS [H]

Synonym: PM0748

Alternate gene names: 15602613

Gene position: 882690-881662 (Counterclockwise)

Preceding gene: 15602614

Following gene: 15602612

Centisome position: 39.1

GC content: 40.33

Gene sequence:

>1029_bases
ATGATCAAAAAACTTTTTCATTCAGTGATGATTGGGTTAGTGTGTGCCGCAGTGATTCTGGTATTTTCACACGTTAACCA
ATTTAGCTTACTCAAAGCACCAGAACCGATGAGCTTTAAAGACGCTGTACGAGTTGCCTCCCCAGCTGTAGTGAATGTCT
ATAATCGTTCTTTTTCGGCGAATAGTGCCGAGCAATTAGAAGTGGGCAATTTAGGATCAGGTGTGATTATGTCAAAAGAT
GGTTATATTTTGACAAATAAACATGTTATTCAAAACGCCGATCAAATTGTGGTCGCATTACAAAATGGGCAACTTTTCGA
TGCCAGTTTAATTGGTTCTGATACTTTGACGGATCTTGCTGTTCTTAAAATTCGTGCGGATAATTTATCGACGATTCCAC
AAAATCCGCAACGACAAATGCATGTTGGTGATGTGGCGTTGGCGATTGGGAATCCCTATAACTTGGGGCAAAGCGTTTCG
CAAGGGATTATTAGTGCAATTGGACGTAATGCGGTGGGGGATTCTGTTGGGCGACAAAACTTTATTCAAACGGATGCTTC
GATTAACCGTGGCAATTCAGGTGGCGCATTAATTAATAGCGTAGGAGAATTAATAGGTATCAATACCCTAAGTATTGGTA
AAACCGCCGGTGAAATTGCCGAAGGGCTAAATTTTGCAATCCCGATTGAATTGGCGAATGATGTGATGAAAAAAATTATT
CGTGATGGACGAGTCATTCGTGGTTACTTTGGTGTACAAAGTGATATTTTATTTAATAATGGTCAAGGTGCCCATTTGGA
AAAAGGGATTTTGATTACCAATGTTAATCCAGAGGGACCAGCAGGTAAGGCAGGCGTGAAAGCCGGCGATATTATTTTAA
AAGTGGGTGATGTTGATGCTATTTCACCCGCGCAAATGATGCAAGTGATCAGCAATACGCGACCTAATACCCGATTGAAT
GTGGTCATTTCTCGTTTAGGAAAAATTATTGAACTTCCTGTGATCATCGAAGAATATCCGTTAAATTAA

Upstream 100 bases:

>100_bases
TAAGCACCTTGGCTGAGGCAAGTTTATGGCAATTGCATTCCATTGAGAAACTCGGCGATGATCTGAAAACGATTTACCAC
CCACGAATTACGGAGCCAAC

Downstream 100 bases:

>100_bases
AAACAAGAAGAGAGTTGTTGTGCAAGCCGTTATTAAAATAAGTCATTTTTTTGCTTGTTTAGATCGCTTACGTTTGATCC
AACGTTGGTCTTTAATGCGT

Product: DegS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MIKKLFHSVMIGLVCAAVILVFSHVNQFSLLKAPEPMSFKDAVRVASPAVVNVYNRSFSANSAEQLEVGNLGSGVIMSKD
GYILTNKHVIQNADQIVVALQNGQLFDASLIGSDTLTDLAVLKIRADNLSTIPQNPQRQMHVGDVALAIGNPYNLGQSVS
QGIISAIGRNAVGDSVGRQNFIQTDASINRGNSGGALINSVGELIGINTLSIGKTAGEIAEGLNFAIPIELANDVMKKII
RDGRVIRGYFGVQSDILFNNGQGAHLEKGILITNVNPEGPAGKAGVKAGDIILKVGDVDAISPAQMMQVISNTRPNTRLN
VVISRLGKIIELPVIIEEYPLN

Sequences:

>Translated_342_residues
MIKKLFHSVMIGLVCAAVILVFSHVNQFSLLKAPEPMSFKDAVRVASPAVVNVYNRSFSANSAEQLEVGNLGSGVIMSKD
GYILTNKHVIQNADQIVVALQNGQLFDASLIGSDTLTDLAVLKIRADNLSTIPQNPQRQMHVGDVALAIGNPYNLGQSVS
QGIISAIGRNAVGDSVGRQNFIQTDASINRGNSGGALINSVGELIGINTLSIGKTAGEIAEGLNFAIPIELANDVMKKII
RDGRVIRGYFGVQSDILFNNGQGAHLEKGILITNVNPEGPAGKAGVKAGDIILKVGDVDAISPAQMMQVISNTRPNTRLN
VVISRLGKIIELPVIIEEYPLN
>Mature_342_residues
MIKKLFHSVMIGLVCAAVILVFSHVNQFSLLKAPEPMSFKDAVRVASPAVVNVYNRSFSANSAEQLEVGNLGSGVIMSKD
GYILTNKHVIQNADQIVVALQNGQLFDASLIGSDTLTDLAVLKIRADNLSTIPQNPQRQMHVGDVALAIGNPYNLGQSVS
QGIISAIGRNAVGDSVGRQNFIQTDASINRGNSGGALINSVGELIGINTLSIGKTAGEIAEGLNFAIPIELANDVMKKII
RDGRVIRGYFGVQSDILFNNGQGAHLEKGILITNVNPEGPAGKAGVKAGDIILKVGDVDAISPAQMMQVISNTRPNTRLN
VVISRLGKIIELPVIIEEYPLN

Specific function: Unknown

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=324, Percent_Identity=32.0987654320988, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI22129776, Length=305, Percent_Identity=29.5081967213115, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI7019477, Length=323, Percent_Identity=29.4117647058824, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI24308541, Length=160, Percent_Identity=37.5, Blast_Score=103, Evalue=2e-22,
Organism=Escherichia coli, GI1789630, Length=353, Percent_Identity=53.2577903682719, Blast_Score=340, Evalue=1e-94,
Organism=Escherichia coli, GI1789629, Length=276, Percent_Identity=42.3913043478261, Blast_Score=188, Evalue=4e-49,
Organism=Escherichia coli, GI1786356, Length=277, Percent_Identity=37.9061371841155, Blast_Score=173, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24646839, Length=306, Percent_Identity=30.0653594771242, Blast_Score=118, Evalue=6e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011783
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 36279; Mature: 36279

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKKLFHSVMIGLVCAAVILVFSHVNQFSLLKAPEPMSFKDAVRVASPAVVNVYNRSFSA
CHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHCCCEEEEEECCCCCC
NSAEQLEVGNLGSGVIMSKDGYILTNKHVIQNADQIVVALQNGQLFDASLIGSDTLTDLA
CCCCCEECCCCCCCEEEECCCEEEECCHHHCCCCEEEEEEECCCEEEHHHCCCCHHHHEE
VLKIRADNLSTIPQNPQRQMHVGDVALAIGNPYNLGQSVSQGIISAIGRNAVGDSVGRQN
EEEEECCCCCCCCCCCCHHEEECEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCHHCCCH
FIQTDASINRGNSGGALINSVGELIGINTLSIGKTAGEIAEGLNFAIPIELANDVMKKII
HEECCCCCCCCCCCCHHHHHHHHHHCCCEEECCCCHHHHHHCCCEEEEHHHHHHHHHHHH
RDGRVIRGYFGVQSDILFNNGQGAHLEKGILITNVNPEGPAGKAGVKAGDIILKVGDVDA
HCCCEEEEECCCCCCEEEECCCCCEEECCEEEEECCCCCCCCCCCCCCCCEEEEECCCCC
ISPAQMMQVISNTRPNTRLNVVISRLGKIIELPVIIEEYPLN
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHEECCEEEECCCCC
>Mature Secondary Structure
MIKKLFHSVMIGLVCAAVILVFSHVNQFSLLKAPEPMSFKDAVRVASPAVVNVYNRSFSA
CHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHCCCEEEEEECCCCCC
NSAEQLEVGNLGSGVIMSKDGYILTNKHVIQNADQIVVALQNGQLFDASLIGSDTLTDLA
CCCCCEECCCCCCCEEEECCCEEEECCHHHCCCCEEEEEEECCCEEEHHHCCCCHHHHEE
VLKIRADNLSTIPQNPQRQMHVGDVALAIGNPYNLGQSVSQGIISAIGRNAVGDSVGRQN
EEEEECCCCCCCCCCCCHHEEECEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCHHCCCH
FIQTDASINRGNSGGALINSVGELIGINTLSIGKTAGEIAEGLNFAIPIELANDVMKKII
HEECCCCCCCCCCCCHHHHHHHHHHCCCEEECCCCHHHHHHCCCEEEEHHHHHHHHHHHH
RDGRVIRGYFGVQSDILFNNGQGAHLEKGILITNVNPEGPAGKAGVKAGDIILKVGDVDA
HCCCEEEEECCCCCCEEEECCCCCEEECCEEEEECCCCCCCCCCCCCCCCEEEEECCCCC
ISPAQMMQVISNTRPNTRLNVVISRLGKIIELPVIIEEYPLN
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHEECCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]