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The map label for this gene is codA [H]

Identifier: 15602430

GI number: 15602430

Start: 649455

End: 650717

Strand: Direct

Name: codA [H]

Synonym: PM0565

Alternate gene names: 15602430

Gene position: 649455-650717 (Clockwise)

Preceding gene: 15602429

Following gene: 15602432

Centisome position: 28.77

GC content: 40.14

Gene sequence:

>1263_bases
ATGTTAATTAAAAATGTTCATCTTGCTGATCGAGAAGGGCTTTGGCAAATTTTGATTGAGGATCAAAAAATAGTGCAAAT
TTGTGCCAATGATGAAGTAATAAATTATGTCGGCGAAATTGTTGATGCAGAAAATGGTATTGCTTATCCACCTTTTGTTG
AACCCCATATTCATTTAGACGCGACACAAACGGCAGGACAACCGAATTGGAACCAATCAGGCACCTTGTTTGAAGGCATT
GAACGTTGGGCAGAGCGTAAATCCTTATTGAGCCATGAAGATGTGAAAGCCCGTGCATGGAAAACGTTAAAATGGCAAAT
TGCAAATGGGGTGCAATATGTGCGTACACATGTGGATGTATCTGATCCCACATTAACGGCACTGAAAGCGATGCTTGAAG
TGAAAAAAGAAGTAGCACCTTGGATTGATTTGCAAATTGTGGCTTTTCCACAAGAAGGGATTTTGTCTTATCCTAATGGT
GAAGCATTACTTGATCAAGCGATGGCGATGGGGGCGGATGTAGTAGGAGGCATTCCACATTTTGAATTTACCCGTGAGTA
TGGCGTCGAGTCCATGCATATCGCGTTTAAGATTGCGCGTAAATACGGAAAACAAATTGATATTCATTGTGATGAAATTG
ATGATGAACAGTCGCGTTTTGTGGAAACCGTTGCTGCTTTAGCCTTGAAGTATGAAATGGGGGATAAAGTTACCGCGAGC
CATACGACAGCAATGCACTCTTATAATGGTGCTTATGCCTCGCGTTTGTTCCGTTTGTTAAAATTGTCAGGCATTCATTT
TGTGGCGAATCCACTAGTGAATATCCATTTGCAAGGGCGTTTTGATACTTATCCAAAACGTCGTGGTATTACCAGAGTGA
AAGAAATGCTGAAAAATAACATTAATGTGTGTTTCGGTCATGATGATGTGTTTGATCCTTGGTATCCATTGGGCACAGCC
AATATGCTACAAGTATTACATATGGGGTTACATGTTTGCCAATTAATGGGCTATGGGCAAATTAATGAAGGGCTAAAATT
AGTGACTGAAAATAGTGCAAAAGCATTAGGTTTAACGGACTATGGTATTCAGGTTGGGCATTCGGCAAACTTGATTATTC
TACCTGCAGAAAATGGTTTTGATGCGGTAAGAAGACAAGTACCAACACGTTATTCTATTCGTGCGGGTAAGATTATTGCA
GAAACGAAATTGGCAGAAACGCAAATTTATCTTGCAGAGAAAGAGAAAGTCAGTTACAGCTAA

Upstream 100 bases:

>100_bases
GGGCATTATTCCTGTCAACGCAGTATTGGGTGGGGCACTGTCTTATCTTCTTCTTAACCCATTCTGTGCAAAAATCTTAG
CAACCAAATAGGAGTGCATC

Downstream 100 bases:

>100_bases
ATATAGTGTAATGATATCTCATCAATAAGACATAAAAGTGCGGTCGAAAATCTTGAAGTTTTCGACCGCACTTATGTTTC
TTTGCTAAGGGTTAGTTATC

Product: cytosine deaminase

Products: NA

Alternate protein names: Cytosine aminohydrolase [H]

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MLIKNVHLADREGLWQILIEDQKIVQICANDEVINYVGEIVDAENGIAYPPFVEPHIHLDATQTAGQPNWNQSGTLFEGI
ERWAERKSLLSHEDVKARAWKTLKWQIANGVQYVRTHVDVSDPTLTALKAMLEVKKEVAPWIDLQIVAFPQEGILSYPNG
EALLDQAMAMGADVVGGIPHFEFTREYGVESMHIAFKIARKYGKQIDIHCDEIDDEQSRFVETVAALALKYEMGDKVTAS
HTTAMHSYNGAYASRLFRLLKLSGIHFVANPLVNIHLQGRFDTYPKRRGITRVKEMLKNNINVCFGHDDVFDPWYPLGTA
NMLQVLHMGLHVCQLMGYGQINEGLKLVTENSAKALGLTDYGIQVGHSANLIILPAENGFDAVRRQVPTRYSIRAGKIIA
ETKLAETQIYLAEKEKVSYS

Sequences:

>Translated_420_residues
MLIKNVHLADREGLWQILIEDQKIVQICANDEVINYVGEIVDAENGIAYPPFVEPHIHLDATQTAGQPNWNQSGTLFEGI
ERWAERKSLLSHEDVKARAWKTLKWQIANGVQYVRTHVDVSDPTLTALKAMLEVKKEVAPWIDLQIVAFPQEGILSYPNG
EALLDQAMAMGADVVGGIPHFEFTREYGVESMHIAFKIARKYGKQIDIHCDEIDDEQSRFVETVAALALKYEMGDKVTAS
HTTAMHSYNGAYASRLFRLLKLSGIHFVANPLVNIHLQGRFDTYPKRRGITRVKEMLKNNINVCFGHDDVFDPWYPLGTA
NMLQVLHMGLHVCQLMGYGQINEGLKLVTENSAKALGLTDYGIQVGHSANLIILPAENGFDAVRRQVPTRYSIRAGKIIA
ETKLAETQIYLAEKEKVSYS
>Mature_420_residues
MLIKNVHLADREGLWQILIEDQKIVQICANDEVINYVGEIVDAENGIAYPPFVEPHIHLDATQTAGQPNWNQSGTLFEGI
ERWAERKSLLSHEDVKARAWKTLKWQIANGVQYVRTHVDVSDPTLTALKAMLEVKKEVAPWIDLQIVAFPQEGILSYPNG
EALLDQAMAMGADVVGGIPHFEFTREYGVESMHIAFKIARKYGKQIDIHCDEIDDEQSRFVETVAALALKYEMGDKVTAS
HTTAMHSYNGAYASRLFRLLKLSGIHFVANPLVNIHLQGRFDTYPKRRGITRVKEMLKNNINVCFGHDDVFDPWYPLGTA
NMLQVLHMGLHVCQLMGYGQINEGLKLVTENSAKALGLTDYGIQVGHSANLIILPAENGFDAVRRQVPTRYSIRAGKIIA
ETKLAETQIYLAEKEKVSYS

Specific function: Unknown

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786531, Length=417, Percent_Identity=77.2182254196643, Blast_Score=687, Evalue=0.0,
Organism=Escherichia coli, GI1786517, Length=410, Percent_Identity=23.6585365853659, Blast_Score=79, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.4.1 [H]

Molecular weight: Translated: 47169; Mature: 47169

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIKNVHLADREGLWQILIEDQKIVQICANDEVINYVGEIVDAENGIAYPPFVEPHIHLD
CEECCCCCCCCCCCEEEEECCCCEEHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEE
ATQTAGQPNWNQSGTLFEGIERWAERKSLLSHEDVKARAWKTLKWQIANGVQYVRTHVDV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHEEEEEHHCCCEEHHEECCC
SDPTLTALKAMLEVKKEVAPWIDLQIVAFPQEGILSYPNGEALLDQAMAMGADVVGGIPH
CCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHCCHHHCCCCC
FEFTREYGVESMHIAFKIARKYGKQIDIHCDEIDDEQSRFVETVAALALKYEMGDKVTAS
CHHHHHHCCCHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEECC
HTTAMHSYNGAYASRLFRLLKLSGIHFVANPLVNIHLQGRFDTYPKRRGITRVKEMLKNN
HHHHHHCCCCHHHHHHHHHHHHCCCCEEECCEEEEEEECCCCCCCHHCCHHHHHHHHHCC
INVCFGHDDVFDPWYPLGTANMLQVLHMGLHVCQLMGYGQINEGLKLVTENSAKALGLTD
CEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEEEC
YGIQVGHSANLIILPAENGFDAVRRQVPTRYSIRAGKIIAETKLAETQIYLAEKEKVSYS
CCEEECCCCCEEEEECCCCHHHHHHHCCCCEEEECCCEEEHHHHHHEEEEEEECCCCCCC
>Mature Secondary Structure
MLIKNVHLADREGLWQILIEDQKIVQICANDEVINYVGEIVDAENGIAYPPFVEPHIHLD
CEECCCCCCCCCCCEEEEECCCCEEHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEE
ATQTAGQPNWNQSGTLFEGIERWAERKSLLSHEDVKARAWKTLKWQIANGVQYVRTHVDV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHEEEEEHHCCCEEHHEECCC
SDPTLTALKAMLEVKKEVAPWIDLQIVAFPQEGILSYPNGEALLDQAMAMGADVVGGIPH
CCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHCCHHHCCCCC
FEFTREYGVESMHIAFKIARKYGKQIDIHCDEIDDEQSRFVETVAALALKYEMGDKVTAS
CHHHHHHCCCHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEECC
HTTAMHSYNGAYASRLFRLLKLSGIHFVANPLVNIHLQGRFDTYPKRRGITRVKEMLKNN
HHHHHHCCCCHHHHHHHHHHHHCCCCEEECCEEEEEEECCCCCCCHHCCHHHHHHHHHCC
INVCFGHDDVFDPWYPLGTANMLQVLHMGLHVCQLMGYGQINEGLKLVTENSAKALGLTD
CEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEEEC
YGIQVGHSANLIILPAENGFDAVRRQVPTRYSIRAGKIIAETKLAETQIYLAEKEKVSYS
CCEEECCCCCEEEEECCCCHHHHHHHCCCCEEEECCCEEEHHHHHHEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1640834; 8450832; 9278503 [H]