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The map label for this gene is glyQS [H]

Identifier: 15594716

GI number: 15594716

Start: 380555

End: 381892

Strand: Reverse

Name: glyQS [H]

Synonym: BB0371

Alternate gene names: 15594716

Gene position: 381892-380555 (Counterclockwise)

Preceding gene: 15594717

Following gene: 15594715

Centisome position: 41.93

GC content: 33.63

Gene sequence:

>1338_bases
ATGGTTAGAATGGAAGATATTATTTCTCTTGCAAAAAGAAAAGGATTTGTATTTCAGTCTTCAGAGGTTTACGGGGGCCT
TTCAGGAGCTTGGGATTATGGTCCTTTGGGGGTTGAGCTTAAAAAGAATATAAAGAAAGAGTGGTGGAAGAGCATGGTGT
ACTTGCATGAAAATATTGTAGGTTTAGATAGTGCTATTTTTATGCGCCCTGAAATTTGGAGAGCATCTGGTCATGTTGAT
GGTTTTTCGGATTCTATGGTTGATTGCAAAGATTGTAAAAGTAGATTTAGAGCTGATTTTATTGATTTGTCAAAAAATTG
TCCGAATTGCAAAGTTGGAAATAATTTTACCTCCCCAAGAAGTTTTAATTTAATGTTTAAGACCCACATTGGAGTAGTGG
AGGATAGTTCTAGTGAAGTTTATTTAAGGCCTGAGACAGCACAAGGAATTTTTGTTAATTTTAGAAATGTTTTGGATTCT
TCAAGGCTTAAGATTCCTTTTGGGATTGCTCAGGTAGGTAAAGCGTTTAGAAATGAGATAGTTACTAAAAATTTTATATT
TAGAACTTGTGAGTTTGAGCAAATGGAAATGCAGTTTTTTGTTCATCCCAAGCAAATAGACGAGTGGTTTTGTTATTGGC
AGCAAAATAGAATGAATTTTTTTATAGAAACTCTTAAAATTAGTCCCGATAGATTAAGATTTAAGGCGCATGATTCAACG
CAGCTTGCTCATTATGCAAAAGCTGCATTTGATATTGAGTATGAATTTCCGTTTGGATTTCAGGAAGTAGAAGGAATTCA
CAATAGAGGTAATTATGATTTAACTCAGCACGCTAAATTTTCTAATAAGCCCAAAGTATTTGAGTATCATGATTTGTTGA
CAAAAGAGAAATATGTGCCTTATGTTATTGAGACTTCTGCTGGTCTTACAAGGTCTGTTTTAATGACTCTTTGTGATGCT
TATTCTGAGGAAGAGCTCTCAGATGGAGACAAGCGTATTGTTTTACGCTTACATCCCAAGTTGGCTCCTTACAAGATTGC
TATATTTCCTCTTGTTAAAAAAGTTGAGCTTACTGAGATTGCTAGAAGGATTTATATGGAGCTTTGCGATGATTTTCATA
TATTTTACGATGATAGTGGAACAATAGGTAAAAGGTATAGACGTCAAGACGAAATAGGAACTCCTTATTGCGTAACAATA
GATTACAATACGATTGAGGATGAGACAGTTACTGTTAGAGAAAGAAATAGCATGACTCAGAAGAGAATTTTTATTAATGA
TTTATATTCATACATTAAAACAGAGATTTTAAATTACAAAGAGGATTTTAATAAATGA

Upstream 100 bases:

>100_bases
TTGATTCTTTAAAATTGATAGGCAAGTCTAAAGTTTTTGAAAGAATAAAATTAGCACAGGAATTTTTAAGAATAAATGAA
TAGCTATTAAGGATATTTTT

Downstream 100 bases:

>100_bases
ATCTTGCTTTAAGTCTTTTACATAAACGCGGATTTTTAAAGCAATGTACATCTTTAAAAGTTTTAAGTGATTTAATGGAT
AGGGAAAAAATAGTTTTTTA

Product: glycyl-tRNA synthetase

Products: NA

Alternate protein names: Glycine--tRNA ligase; GlyRS [H]

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MVRMEDIISLAKRKGFVFQSSEVYGGLSGAWDYGPLGVELKKNIKKEWWKSMVYLHENIVGLDSAIFMRPEIWRASGHVD
GFSDSMVDCKDCKSRFRADFIDLSKNCPNCKVGNNFTSPRSFNLMFKTHIGVVEDSSSEVYLRPETAQGIFVNFRNVLDS
SRLKIPFGIAQVGKAFRNEIVTKNFIFRTCEFEQMEMQFFVHPKQIDEWFCYWQQNRMNFFIETLKISPDRLRFKAHDST
QLAHYAKAAFDIEYEFPFGFQEVEGIHNRGNYDLTQHAKFSNKPKVFEYHDLLTKEKYVPYVIETSAGLTRSVLMTLCDA
YSEEELSDGDKRIVLRLHPKLAPYKIAIFPLVKKVELTEIARRIYMELCDDFHIFYDDSGTIGKRYRRQDEIGTPYCVTI
DYNTIEDETVTVRERNSMTQKRIFINDLYSYIKTEILNYKEDFNK

Sequences:

>Translated_445_residues
MVRMEDIISLAKRKGFVFQSSEVYGGLSGAWDYGPLGVELKKNIKKEWWKSMVYLHENIVGLDSAIFMRPEIWRASGHVD
GFSDSMVDCKDCKSRFRADFIDLSKNCPNCKVGNNFTSPRSFNLMFKTHIGVVEDSSSEVYLRPETAQGIFVNFRNVLDS
SRLKIPFGIAQVGKAFRNEIVTKNFIFRTCEFEQMEMQFFVHPKQIDEWFCYWQQNRMNFFIETLKISPDRLRFKAHDST
QLAHYAKAAFDIEYEFPFGFQEVEGIHNRGNYDLTQHAKFSNKPKVFEYHDLLTKEKYVPYVIETSAGLTRSVLMTLCDA
YSEEELSDGDKRIVLRLHPKLAPYKIAIFPLVKKVELTEIARRIYMELCDDFHIFYDDSGTIGKRYRRQDEIGTPYCVTI
DYNTIEDETVTVRERNSMTQKRIFINDLYSYIKTEILNYKEDFNK
>Mature_445_residues
MVRMEDIISLAKRKGFVFQSSEVYGGLSGAWDYGPLGVELKKNIKKEWWKSMVYLHENIVGLDSAIFMRPEIWRASGHVD
GFSDSMVDCKDCKSRFRADFIDLSKNCPNCKVGNNFTSPRSFNLMFKTHIGVVEDSSSEVYLRPETAQGIFVNFRNVLDS
SRLKIPFGIAQVGKAFRNEIVTKNFIFRTCEFEQMEMQFFVHPKQIDEWFCYWQQNRMNFFIETLKISPDRLRFKAHDST
QLAHYAKAAFDIEYEFPFGFQEVEGIHNRGNYDLTQHAKFSNKPKVFEYHDLLTKEKYVPYVIETSAGLTRSVLMTLCDA
YSEEELSDGDKRIVLRLHPKLAPYKIAIFPLVKKVELTEIARRIYMELCDDFHIFYDDSGTIGKRYRRQDEIGTPYCVTI
DYNTIEDETVTVRERNSMTQKRIFINDLYSYIKTEILNYKEDFNK

Specific function: Catalyzes the attachment of glycine to tRNA(Gly) [H]

COG id: COG0423

COG function: function code J; Glycyl-tRNA synthetase (class II)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI116805340, Length=370, Percent_Identity=31.6216216216216, Blast_Score=172, Evalue=7e-43,
Organism=Homo sapiens, GI70887790, Length=447, Percent_Identity=23.0425055928412, Blast_Score=107, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI32564541, Length=371, Percent_Identity=32.3450134770889, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17554996, Length=371, Percent_Identity=32.3450134770889, Blast_Score=166, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6325338, Length=415, Percent_Identity=27.710843373494, Blast_Score=139, Evalue=9e-34,
Organism=Saccharomyces cerevisiae, GI6319597, Length=283, Percent_Identity=28.6219081272085, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI21357965, Length=360, Percent_Identity=32.5, Blast_Score=165, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24664462, Length=360, Percent_Identity=32.5, Blast_Score=165, Evalue=6e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR022961
- InterPro:   IPR002315 [H]

Pfam domain/function: PF03129 HGTP_anticodon; PF00587 tRNA-synt_2b [H]

EC number: =6.1.1.14 [H]

Molecular weight: Translated: 52210; Mature: 52210

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRMEDIISLAKRKGFVFQSSEVYGGLSGAWDYGPLGVELKKNIKKEWWKSMVYLHENIV
CCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GLDSAIFMRPEIWRASGHVDGFSDSMVDCKDCKSRFRADFIDLSKNCPNCKVGNNFTSPR
CCCCCEEECCHHEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
SFNLMFKTHIGVVEDSSSEVYLRPETAQGIFVNFRNVLDSSRLKIPFGIAQVGKAFRNEI
EEEEEEEEECCEEECCCCEEEECCCCCCEEEEEHHHHHCCCCEECCCCHHHHHHHHHHHH
VTKNFIFRTCEFEQMEMQFFVHPKQIDEWFCYWQQNRMNFFIETLKISPDRLRFKAHDST
CCHHHEEEECCHHHEEEEEEECHHHHHHHHHHHHCCCCEEEEEEEECCHHHEEEEECCCH
QLAHYAKAAFDIEYEFPFGFQEVEGIHNRGNYDLTQHAKFSNKPKVFEYHDLLTKEKYVP
HHHHHHHHHEEEEEECCCCHHHHHHHHCCCCCCCHHCCCCCCCCCEEEHHHHHCCCCCCC
YVIETSAGLTRSVLMTLCDAYSEEELSDGDKRIVLRLHPKLAPYKIAIFPLVKKVELTEI
EEEECCCCHHHHHHHHHHHHCCHHHCCCCCEEEEEEECCCCCCEEEEEEHHHHHHHHHHH
ARRIYMELCDDFHIFYDDSGTIGKRYRRQDEIGTPYCVTIDYNTIEDETVTVRERNSMTQ
HHHHHHHHHCCEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEHHCCHHH
KRIFINDLYSYIKTEILNYKEDFNK
HHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVRMEDIISLAKRKGFVFQSSEVYGGLSGAWDYGPLGVELKKNIKKEWWKSMVYLHENIV
CCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GLDSAIFMRPEIWRASGHVDGFSDSMVDCKDCKSRFRADFIDLSKNCPNCKVGNNFTSPR
CCCCCEEECCHHEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
SFNLMFKTHIGVVEDSSSEVYLRPETAQGIFVNFRNVLDSSRLKIPFGIAQVGKAFRNEI
EEEEEEEEECCEEECCCCEEEECCCCCCEEEEEHHHHHCCCCEECCCCHHHHHHHHHHHH
VTKNFIFRTCEFEQMEMQFFVHPKQIDEWFCYWQQNRMNFFIETLKISPDRLRFKAHDST
CCHHHEEEECCHHHEEEEEEECHHHHHHHHHHHHCCCCEEEEEEEECCHHHEEEEECCCH
QLAHYAKAAFDIEYEFPFGFQEVEGIHNRGNYDLTQHAKFSNKPKVFEYHDLLTKEKYVP
HHHHHHHHHEEEEEECCCCHHHHHHHHCCCCCCCHHCCCCCCCCCEEEHHHHHCCCCCCC
YVIETSAGLTRSVLMTLCDAYSEEELSDGDKRIVLRLHPKLAPYKIAIFPLVKKVELTEI
EEEECCCCHHHHHHHHHHHHCCHHHCCCCCEEEEEEECCCCCCEEEEEEHHHHHHHHHHH
ARRIYMELCDDFHIFYDDSGTIGKRYRRQDEIGTPYCVTIDYNTIEDETVTVRERNSMTQ
HHHHHHHHHCCEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEHHCCHHH
KRIFINDLYSYIKTEILNYKEDFNK
HHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA