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The map label for this gene is uppP

Identifier: 15594603

GI number: 15594603

Start: 269673

End: 270473

Strand: Reverse

Name: uppP

Synonym: BB0258

Alternate gene names: 15594603

Gene position: 270473-269673 (Counterclockwise)

Preceding gene: 15594604

Following gene: 15594602

Centisome position: 29.7

GC content: 24.97

Gene sequence:

>801_bases
ATGACAAATATTTTAAGTGCAATTATTTTGGGCATTATTCAAGGCATTACAGAGTTTTTACCAATATCTAGTTCGGGACA
TTTATTGCTTTTTAGGCATTTTATAAATTTAAAGCTCTCAATAATATTTGATATTTATTTACATCTTGCAACAGTTTTGG
TGATTATTATTTACTATCGTAAAAGGATTTTGGAGCTTTTTTTAACTTTTATTAGATTTTCTTTAAGAAAAACTGTTAAA
TCTGATTTAACAAACTTAAAATTAATATTGCTAATATTGATAATAACCATTGTTACCGGAGTTGTTGGGACTTTTATTTC
AAAATACGAGAGTATGTTTACATTGTCTTTCGTTTTAATTAATTTTATTATAACAGGGATTTTAATCTTGATGCTAGAAT
TTAATTTTTTAAAAGTTGATTTTAAAGGTAATATTTTGTTAGCAGGAATTTTTATGGGGCTGATGCAAGGCTTGGGTGCG
CTTCCAGGAATCTCTCGTTCAGGAATTACGATCTTTTCGGCATCGGTTATTGGATTTAATAGAAAAAGTGCATTTGAAAT
TTCATTTTTATCTTTAATTCCAATAGTTTTTGGAGCGATTTTATTAAAACATAAAGAATTTTATGATATTTTTATGGTTT
TAAATTTTTTTGAAATAAACTTAGGAGCATTAGTTGCTTTTGTTGTTGGTATTTTCTCAATAAATTTCTTTTTTAAAATG
CTTAATAACAAAAAACTGTATTATTTTTCTATATATTTATTTGCACTTTCAATTATAGTTTGTTATTTTGTTAGAATATG
A

Upstream 100 bases:

>100_bases
ATTCGGTATTTTATGATGCTTTGTATGAAAAGAAGGGAATAGATTCAGTAATAGTTAAAATTATGGGCGAATTCCCCAAA
AATTAATATTGGAGCATTTA

Downstream 100 bases:

>100_bases
AAGATTTTTATCAGTATTTTCAATTTTTGTTTTTTTTCATGCTTTCGGTTATTTCTTTTTCTCTTTTTGTAGCATTAACC
CCTTTGAGCAATGTATTTGT

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MTNILSAIILGIIQGITEFLPISSSGHLLLFRHFINLKLSIIFDIYLHLATVLVIIIYYRKRILELFLTFIRFSLRKTVK
SDLTNLKLILLILIITIVTGVVGTFISKYESMFTLSFVLINFIITGILILMLEFNFLKVDFKGNILLAGIFMGLMQGLGA
LPGISRSGITIFSASVIGFNRKSAFEISFLSLIPIVFGAILLKHKEFYDIFMVLNFFEINLGALVAFVVGIFSINFFFKM
LNNKKLYYFSIYLFALSIIVCYFVRI

Sequences:

>Translated_266_residues
MTNILSAIILGIIQGITEFLPISSSGHLLLFRHFINLKLSIIFDIYLHLATVLVIIIYYRKRILELFLTFIRFSLRKTVK
SDLTNLKLILLILIITIVTGVVGTFISKYESMFTLSFVLINFIITGILILMLEFNFLKVDFKGNILLAGIFMGLMQGLGA
LPGISRSGITIFSASVIGFNRKSAFEISFLSLIPIVFGAILLKHKEFYDIFMVLNFFEINLGALVAFVVGIFSINFFFKM
LNNKKLYYFSIYLFALSIIVCYFVRI
>Mature_265_residues
TNILSAIILGIIQGITEFLPISSSGHLLLFRHFINLKLSIIFDIYLHLATVLVIIIYYRKRILELFLTFIRFSLRKTVKS
DLTNLKLILLILIITIVTGVVGTFISKYESMFTLSFVLINFIITGILILMLEFNFLKVDFKGNILLAGIFMGLMQGLGAL
PGISRSGITIFSASVIGFNRKSAFEISFLSLIPIVFGAILLKHKEFYDIFMVLNFFEINLGALVAFVVGIFSINFFFKML
NNKKLYYFSIYLFALSIIVCYFVRI

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=275, Percent_Identity=28.7272727272727, Blast_Score=96, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_BORBU (O51273)

Other databases:

- EMBL:   AE000783
- PIR:   B70132
- RefSeq:   NP_212392.1
- EnsemblBacteria:   EBBORT00000008457
- GeneID:   1195095
- GenomeReviews:   AE000783_GR
- KEGG:   bbu:BB0258
- NMPDR:   fig|224326.1.peg.642
- TIGR:   BB_0258
- GeneTree:   EBGT00050000006834
- HOGENOM:   HBG391969
- OMA:   CRRILEL
- ProtClustDB:   PRK00281
- BioCyc:   BBUR224326:BB_0258-MONOMER
- BRENDA:   3.6.1.27
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 30271; Mature: 30140

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xbb399f0)-; HASH(0xc703d30)-; HASH(0xc711ebc)-; HASH(0xb6dce08)-; HASH(0xc711df0)-; HASH(0xc6fece4)-; HASH(0xc711c28)-; HASH(0xc0f6310)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNILSAIILGIIQGITEFLPISSSGHLLLFRHFINLKLSIIFDIYLHLATVLVIIIYYR
CHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRILELFLTFIRFSLRKTVKSDLTNLKLILLILIITIVTGVVGTFISKYESMFTLSFVLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NFIITGILILMLEFNFLKVDFKGNILLAGIFMGLMQGLGALPGISRSGITIFSASVIGFN
HHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHHCCC
RKSAFEISFLSLIPIVFGAILLKHKEFYDIFMVLNFFEINLGALVAFVVGIFSINFFFKM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNNKKLYYFSIYLFALSIIVCYFVRI
HCCCCCHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure 
TNILSAIILGIIQGITEFLPISSSGHLLLFRHFINLKLSIIFDIYLHLATVLVIIIYYR
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRILELFLTFIRFSLRKTVKSDLTNLKLILLILIITIVTGVVGTFISKYESMFTLSFVLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NFIITGILILMLEFNFLKVDFKGNILLAGIFMGLMQGLGALPGISRSGITIFSASVIGFN
HHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHHCCC
RKSAFEISFLSLIPIVFGAILLKHKEFYDIFMVLNFFEINLGALVAFVVGIFSINFFFKM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNNKKLYYFSIYLFALSIIVCYFVRI
HCCCCCHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9403685