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The map label for this gene is ftsK

Identifier: 15594602

GI number: 15594602

Start: 267313

End: 269676

Strand: Reverse

Name: ftsK

Synonym: BB0257

Alternate gene names: 15594602

Gene position: 269676-267313 (Counterclockwise)

Preceding gene: 15594603

Following gene: 15594598

Centisome position: 29.61

GC content: 28.86

Gene sequence:

>2364_bases
ATGAAAGATTTTTATCAGTATTTTCAATTTTTGTTTTTTTTCATGCTTTCGGTTATTTCTTTTTCTCTTTTTGTAGCATT
AACCCCTTTGAGCAATGTATTTGTATTTTTTGTTTTCAATTTACTAGGGCAAATACTTCTTAATGTTTTTTCATTTTTGT
CATTTTATTTAATAGTATATCCAATTGTTAATTGGTACGCCTATAAAAAACATATTTTTACTAAACGATTTATATTTAAT
TGGAATTATACCGTAATATTGTTTTTTACTTTAATATTTTTAATAAAAATTAATTCTAATGTTGAAAAATCTTATTTTAT
TAAGATATTTCTTATTAATTTTGGTATAGTATTGGGGAATTTTTTTATTTTTACTCTTTTAATTTTAGAATTTGTTGTGT
GGATTTACTTAAATTATGTCTTTTTTAAGGATGTTAATTTTATTTTAGATACTTTTAAATTTTTAGAGTTTAAGATTAAA
ATTTTGTTTGAAAATATATTAAGTTATTTTCCCTTTTCAAATTCATTGGATGTAAAAAAAGATATTAAAGTTTATGGAGA
TTCTGTAGATGATCTTAAAGATTCTCAAGTTTTTGATGAAAAAAAGAATATTATTAATGATGAAGAATATCAGGCTTTAT
GGTCATTTAGCGCCTTTTTAAGAAACAATAAAAAGCCTTCCAATATTAATTTAGACAAAACTATTTTTGAAGGCTCAGAT
CTCAAAGAAGCAAGCTCTTTAAATAAGGATATTTTAAATGAGAATGCTTTAAATTTAGATGAAAATGTAGATGAAATTGA
TGAGTCTTGTGAGTATAAATATTTAGACAATCTTGAGGATAATAAGTTAGTTATTAGTGGAAAGGTTAAAGCCTGTGAGA
TAAGAACTAAGGGCATAATTAGTCAGGTCGCTATTTCTCATGTTTATAACGAAAATGTAGCTTTGAATAAAAAAAATGAT
TCTTACGTTATTGATATTTCAGTTTTTGACCAGAAAGAGATTAAAAATGATGTAGAGGATATTGAATATGATAAAGAAAT
TCAAAAGCAATCAATGATTCTCCAGGAGACATTAAAAGAGTTTAATATTAATGCTAAATTAATTGATATTATTAAAGGCC
CTGTTGTTACAATGTATGCTGTTCGTCCAGATAAGGGAATTAAGCTTTCTAAGATTACTTCTATTTCTGATAATATTGCC
TTAAGGCTTGCGGCTATTAGGGTTAGGATTATTGCTCCAATTCCTGGCAGAGAAGCTGTAGGAATTGAAATTCCCAATAA
AAGGCGTGAGTTTATTTTAATTTCAGAGATAATAGACAGCAAGGAATTTAGAGGTGATTTTAGAATTCCTTTTGCTCTTG
GAAAGGAGATTAGTGGCGAAAATATTGTTTTTGACCTTGTTAATTCTCCACATTTATTAATAGCTGGTGCAACTGGGGCG
GGTAAATCTGTTTGTGTGAATTCTTTAATTGCTTCAATTATTTTTTCAAAATCTCCAGATGAAGTGAAATTAATTATGAT
AGATCCCAAAATAGTTGAGCTTAAACTTTTTAATGATATTCCTCATTTATTAACTCCAGTTATTACAGATGTAAAGAGAG
CCTTAGAGGCTCTTAGATGGTGTCTTGATGAAATGGAAAGAAGGTATGTGCTTCTTGATAATTTATTGGTAAGAGATATT
TCTTCTTATAATAAAAAAATAAAAGATGAGAATTTGAATTTAATGATTTTGCCATATCTTGTAATAATTATTGATGAATT
TGCAGATCTTATTCTTTCTGCAAGAAAAGATTTGGAAAATTTAATTTCTAGACTTGCTGCAATGGCTAGAGCTGTGGGGA
TTCATTTGGTTCTTGCGACCCAAAGACCTTCTGTTGATGTTATTACGGGCGTAATAAAAGCCAATTTTCCTTCAAGGATT
TCTTTCATGGTGGCCAGCTCTATGGATTCGAGAATAATTCTTGGATCTTCTGGTGCTGAAAAACTTTTAGGAAAGGGGGA
TATGCTTTATATTAGCTCTTTAAATCCTTTTCCTCMAAGAATTCAGGGTGGATTTTTAAAGGAAAGAGAAGTTTACAGGC
TTGTTGAAGAGGTTAAAAAATTTGGTTCTCCAAATTATATTGATGATGAAATATTTATTGATAGTGTAAAAGAGCCAGAT
TTGGTTGCTCTTGGACCTTCTGATGAGCCAATGTTTGATGAAGCTCTTGAGATTGTTAAAACCACAAGAAAAGCCTCAGC
ATCTTATCTGCAAAGAAGACTGAAGATAGGTTACAACAGAGCAGCTAGAATTATTGAAATTATGGAAGATATGGGATATG
TAGGACCTGTTAATGGATCAAAGCCAAGAGAGGTGTTAATTTAA

Upstream 100 bases:

>100_bases
CAATAAATTTCTTTTTTAAAATGCTTAATAACAAAAAACTGTATTATTTTTCTATATATTTATTTGCACTTTCAATTATA
GTTTGTTATTTTGTTAGAAT

Downstream 100 bases:

>100_bases
AATAAAGAGATATCCATTTGAACATCTCTTGTGCGATCTATCTATTAGTTTTTTGTTTTAATTTTCTTACTTTTTTTGCC
TGTTTTCTTTTAAAAGCTTT

Product: cell division protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 787; Mature: 787

Protein sequence:

>787_residues
MKDFYQYFQFLFFFMLSVISFSLFVALTPLSNVFVFFVFNLLGQILLNVFSFLSFYLIVYPIVNWYAYKKHIFTKRFIFN
WNYTVILFFTLIFLIKINSNVEKSYFIKIFLINFGIVLGNFFIFTLLILEFVVWIYLNYVFFKDVNFILDTFKFLEFKIK
ILFENILSYFPFSNSLDVKKDIKVYGDSVDDLKDSQVFDEKKNIINDEEYQALWSFSAFLRNNKKPSNINLDKTIFEGSD
LKEASSLNKDILNENALNLDENVDEIDESCEYKYLDNLEDNKLVISGKVKACEIRTKGIISQVAISHVYNENVALNKKND
SYVIDISVFDQKEIKNDVEDIEYDKEIQKQSMILQETLKEFNINAKLIDIIKGPVVTMYAVRPDKGIKLSKITSISDNIA
LRLAAIRVRIIAPIPGREAVGIEIPNKRREFILISEIIDSKEFRGDFRIPFALGKEISGENIVFDLVNSPHLLIAGATGA
GKSVCVNSLIASIIFSKSPDEVKLIMIDPKIVELKLFNDIPHLLTPVITDVKRALEALRWCLDEMERRYVLLDNLLVRDI
SSYNKKIKDENLNLMILPYLVIIIDEFADLILSARKDLENLISRLAAMARAVGIHLVLATQRPSVDVITGVIKANFPSRI
SFMVASSMDSRIILGSSGAEKLLGKGDMLYISSLNPFPXRIQGGFLKEREVYRLVEEVKKFGSPNYIDDEIFIDSVKEPD
LVALGPSDEPMFDEALEIVKTTRKASASYLQRRLKIGYNRAARIIEIMEDMGYVGPVNGSKPREVLI

Sequences:

>Translated_787_residues
MKDFYQYFQFLFFFMLSVISFSLFVALTPLSNVFVFFVFNLLGQILLNVFSFLSFYLIVYPIVNWYAYKKHIFTKRFIFN
WNYTVILFFTLIFLIKINSNVEKSYFIKIFLINFGIVLGNFFIFTLLILEFVVWIYLNYVFFKDVNFILDTFKFLEFKIK
ILFENILSYFPFSNSLDVKKDIKVYGDSVDDLKDSQVFDEKKNIINDEEYQALWSFSAFLRNNKKPSNINLDKTIFEGSD
LKEASSLNKDILNENALNLDENVDEIDESCEYKYLDNLEDNKLVISGKVKACEIRTKGIISQVAISHVYNENVALNKKND
SYVIDISVFDQKEIKNDVEDIEYDKEIQKQSMILQETLKEFNINAKLIDIIKGPVVTMYAVRPDKGIKLSKITSISDNIA
LRLAAIRVRIIAPIPGREAVGIEIPNKRREFILISEIIDSKEFRGDFRIPFALGKEISGENIVFDLVNSPHLLIAGATGA
GKSVCVNSLIASIIFSKSPDEVKLIMIDPKIVELKLFNDIPHLLTPVITDVKRALEALRWCLDEMERRYVLLDNLLVRDI
SSYNKKIKDENLNLMILPYLVIIIDEFADLILSARKDLENLISRLAAMARAVGIHLVLATQRPSVDVITGVIKANFPSRI
SFMVASSMDSRIILGSSGAEKLLGKGDMLYISSLNPFPXRIQGGFLKEREVYRLVEEVKKFGSPNYIDDEIFIDSVKEPD
LVALGPSDEPMFDEALEIVKTTRKASASYLQRRLKIGYNRAARIIEIMEDMGYVGPVNGSKPREVLI
>Mature_787_residues
MKDFYQYFQFLFFFMLSVISFSLFVALTPLSNVFVFFVFNLLGQILLNVFSFLSFYLIVYPIVNWYAYKKHIFTKRFIFN
WNYTVILFFTLIFLIKINSNVEKSYFIKIFLINFGIVLGNFFIFTLLILEFVVWIYLNYVFFKDVNFILDTFKFLEFKIK
ILFENILSYFPFSNSLDVKKDIKVYGDSVDDLKDSQVFDEKKNIINDEEYQALWSFSAFLRNNKKPSNINLDKTIFEGSD
LKEASSLNKDILNENALNLDENVDEIDESCEYKYLDNLEDNKLVISGKVKACEIRTKGIISQVAISHVYNENVALNKKND
SYVIDISVFDQKEIKNDVEDIEYDKEIQKQSMILQETLKEFNINAKLIDIIKGPVVTMYAVRPDKGIKLSKITSISDNIA
LRLAAIRVRIIAPIPGREAVGIEIPNKRREFILISEIIDSKEFRGDFRIPFALGKEISGENIVFDLVNSPHLLIAGATGA
GKSVCVNSLIASIIFSKSPDEVKLIMIDPKIVELKLFNDIPHLLTPVITDVKRALEALRWCLDEMERRYVLLDNLLVRDI
SSYNKKIKDENLNLMILPYLVIIIDEFADLILSARKDLENLISRLAAMARAVGIHLVLATQRPSVDVITGVIKANFPSRI
SFMVASSMDSRIILGSSGAEKLLGKGDMLYISSLNPFPXRIQGGFLKEREVYRLVEEVKKFGSPNYIDDEIFIDSVKEPD
LVALGPSDEPMFDEALEIVKTTRKASASYLQRRLKIGYNRAARIIEIMEDMGYVGPVNGSKPREVLI

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain

Homologues:

Organism=Escherichia coli, GI1787117, Length=465, Percent_Identity=44.7311827956989, Blast_Score=407, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FTSK_BORBU (O51272)

Other databases:

- EMBL:   AE000783
- PIR:   A70132
- RefSeq:   NP_212391.1
- EnsemblBacteria:   EBBORT00000008414
- GeneID:   1195094
- GenomeReviews:   AE000783_GR
- KEGG:   bbu:BB0257
- NMPDR:   fig|224326.1.peg.641
- TIGR:   BB_0257
- GeneTree:   EBGT00050000007469
- HOGENOM:   HBG662140
- OMA:   WIYLNYV
- ProtClustDB:   CLSK507472
- BioCyc:   BBUR224326:BB_0257-MONOMER
- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543
- SMART:   SM00382
- SMART:   SM00843

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE

EC number: NA

Molecular weight: Translated: 90214; Mature: 90214

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xb0d0f6c)-; HASH(0xb2d8904)-; HASH(0xbdb103c)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDFYQYFQFLFFFMLSVISFSLFVALTPLSNVFVFFVFNLLGQILLNVFSFLSFYLIVY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PIVNWYAYKKHIFTKRFIFNWNYTVILFFTLIFLIKINSNVEKSYFIKIFLINFGIVLGN
HHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHCCCCCCCHHEEEEHHHHHHHHHHH
FFIFTLLILEFVVWIYLNYVFFKDVNFILDTFKFLEFKIKILFENILSYFPFSNSLDVKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
DIKVYGDSVDDLKDSQVFDEKKNIINDEEYQALWSFSAFLRNNKKPSNINLDKTIFEGSD
HHHEECCCHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCC
LKEASSLNKDILNENALNLDENVDEIDESCEYKYLDNLEDNKLVISGKVKACEIRTKGII
CHHHHHCCHHHHCCCCCCCCCCHHHHHHCCCCHHHCCCCCCEEEEECCCEEEEEHHHHHH
SQVAISHVYNENVALNKKNDSYVIDISVFDQKEIKNDVEDIEYDKEIQKQSMILQETLKE
HHHHHHHHHCCCEEEECCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FNINAKLIDIIKGPVVTMYAVRPDKGIKLSKITSISDNIALRLAAIRVRIIAPIPGREAV
HCCCCEEEHHHCCCEEEEEEECCCCCCEEEEECCCCCCHHEEEEEEEEEEEECCCCCCEE
GIEIPNKRREFILISEIIDSKEFRGDFRIPFALGKEISGENIVFDLVNSPHLLIAGATGA
EEECCCCCCCEEEHHHHHCCHHCCCCCCCCHHHCCCCCCCCEEEEECCCCEEEEEECCCC
GKSVCVNSLIASIIFSKSPDEVKLIMIDPKIVELKLFNDIPHLLTPVITDVKRALEALRW
CHHHHHHHHHHHHHHCCCCCCEEEEEECCEEEEEEEHHCCHHHHHHHHHHHHHHHHHHHH
CLDEMERRYVLLDNLLVRDISSYNKKIKDENLNLMILPYLVIIIDEFADLILSARKDLEN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
LISRLAAMARAVGIHLVLATQRPSVDVITGVIKANFPSRISFMVASSMDSRIILGSSGAE
HHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHCCCCHHHHHHEECCCCCEEEEECCCHH
KLLGKGDMLYISSLNPFPXRIQGGFLKEREVYRLVEEVKKFGSPNYIDDEIFIDSVKEPD
HHHCCCCEEEEECCCCCCCHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCC
LVALGPSDEPMFDEALEIVKTTRKASASYLQRRLKIGYNRAARIIEIMEDMGYVGPVNGS
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCC
KPREVLI
CCCCCCH
>Mature Secondary Structure
MKDFYQYFQFLFFFMLSVISFSLFVALTPLSNVFVFFVFNLLGQILLNVFSFLSFYLIVY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PIVNWYAYKKHIFTKRFIFNWNYTVILFFTLIFLIKINSNVEKSYFIKIFLINFGIVLGN
HHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHCCCCCCCHHEEEEHHHHHHHHHHH
FFIFTLLILEFVVWIYLNYVFFKDVNFILDTFKFLEFKIKILFENILSYFPFSNSLDVKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
DIKVYGDSVDDLKDSQVFDEKKNIINDEEYQALWSFSAFLRNNKKPSNINLDKTIFEGSD
HHHEECCCHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCC
LKEASSLNKDILNENALNLDENVDEIDESCEYKYLDNLEDNKLVISGKVKACEIRTKGII
CHHHHHCCHHHHCCCCCCCCCCHHHHHHCCCCHHHCCCCCCEEEEECCCEEEEEHHHHHH
SQVAISHVYNENVALNKKNDSYVIDISVFDQKEIKNDVEDIEYDKEIQKQSMILQETLKE
HHHHHHHHHCCCEEEECCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FNINAKLIDIIKGPVVTMYAVRPDKGIKLSKITSISDNIALRLAAIRVRIIAPIPGREAV
HCCCCEEEHHHCCCEEEEEEECCCCCCEEEEECCCCCCHHEEEEEEEEEEEECCCCCCEE
GIEIPNKRREFILISEIIDSKEFRGDFRIPFALGKEISGENIVFDLVNSPHLLIAGATGA
EEECCCCCCCEEEHHHHHCCHHCCCCCCCCHHHCCCCCCCCEEEEECCCCEEEEEECCCC
GKSVCVNSLIASIIFSKSPDEVKLIMIDPKIVELKLFNDIPHLLTPVITDVKRALEALRW
CHHHHHHHHHHHHHHCCCCCCEEEEEECCEEEEEEEHHCCHHHHHHHHHHHHHHHHHHHH
CLDEMERRYVLLDNLLVRDISSYNKKIKDENLNLMILPYLVIIIDEFADLILSARKDLEN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
LISRLAAMARAVGIHLVLATQRPSVDVITGVIKANFPSRISFMVASSMDSRIILGSSGAE
HHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHCCCCHHHHHHEECCCCCEEEEECCCHH
KLLGKGDMLYISSLNPFPXRIQGGFLKEREVYRLVEEVKKFGSPNYIDDEIFIDSVKEPD
HHHCCCCEEEEECCCCCCCHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCC
LVALGPSDEPMFDEALEIVKTTRKASASYLQRRLKIGYNRAARIIEIMEDMGYVGPVNGS
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCC
KPREVLI
CCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9403685