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The map label for this gene is plsC

Identifier: 15594383

GI number: 15594383

Start: 35857

End: 36609

Strand: Reverse

Name: plsC

Synonym: BB0037

Alternate gene names: 15594383

Gene position: 36609-35857 (Counterclockwise)

Preceding gene: 15594384

Following gene: 15594382

Centisome position: 4.02

GC content: 27.36

Gene sequence:

>753_bases
ATGATAATAGTTTTTATGAAAATATTGAGAAGTATTATAACTTATTTTAATGTTTTATTGTTTTTTTTGATTTTAATTTT
TTTTTTATTTCCTTTTTACCTGGTTTGTAAAATTTTTTTAATTGAACGTTATGTTGTTAGGCTTAGTTTCATTATGATGC
GAGCTTGCATTAAAATTAGCTTATGGCTTGCTGGAATTAAAATTATTGTTACGGGTTCTGAAAATATTCCTAAAAAAAGC
AATGTAATAATAATGGGAAATCATATTGCGGCTATGGATCCTTTAATTTTTATTTATACTTTTGCCTGCCCATTTGTAAT
ATTGGCAAAACATTCGTTGCTTAGGATTCCTTTTGTGAATATTGTTTTGATTGTTATGGGTGTTATTTTTGTTAATAGAA
GGAGCATAAGATCTGCTGCTGCTGCTGAGGTTAAGGCAATAAAGGTTATGAGAGAAGGTAGATCTATTGGAATTTTCCCC
GAAGGAACTAGAAATAGAGGGGGGGATACTAGAGTTTTTAAAAAAGGTTCAATTAAGATGGCATTAAAAACAGGAACATC
AATTCTTCCTGTTACTCTTTATAATACTAATAACTTTTTTATTAAAAATATTATTTTTAATTCTGGACTGTCTGTTTATA
TTCATGTCCATCCTTTGATAGATGTTTTAAAATTAAGTGAGTATGAAAAAGAGAATCTCACTAGTATTATTAGAGATCAA
ATAGTTAAAAAGCTTGAAACTATTAAAATTTAA

Upstream 100 bases:

>100_bases
AAAAATTTTCTACAATCATTTTAAATCCTATTAAAATTTTAAAAGATGATGTAAGCTTAGTTAAAGGGCAAAAATTAAAG
CTTGAGCGAATAGAAAAAAT

Downstream 100 bases:

>100_bases
TTTATAAAGCAAGGATTTAGATGAAGACTCAAAATTATGATGAAAGTAAAATAATCACTCTATCTTCTCTTGAACATATT
AGATTAAGATCTGGTATGTA

Product: 1-acyl-sn-glycerol-3-phosphate acetyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MIIVFMKILRSIITYFNVLLFFLILIFFLFPFYLVCKIFLIERYVVRLSFIMMRACIKISLWLAGIKIIVTGSENIPKKS
NVIIMGNHIAAMDPLIFIYTFACPFVILAKHSLLRIPFVNIVLIVMGVIFVNRRSIRSAAAAEVKAIKVMREGRSIGIFP
EGTRNRGGDTRVFKKGSIKMALKTGTSILPVTLYNTNNFFIKNIIFNSGLSVYIHVHPLIDVLKLSEYEKENLTSIIRDQ
IVKKLETIKI

Sequences:

>Translated_250_residues
MIIVFMKILRSIITYFNVLLFFLILIFFLFPFYLVCKIFLIERYVVRLSFIMMRACIKISLWLAGIKIIVTGSENIPKKS
NVIIMGNHIAAMDPLIFIYTFACPFVILAKHSLLRIPFVNIVLIVMGVIFVNRRSIRSAAAAEVKAIKVMREGRSIGIFP
EGTRNRGGDTRVFKKGSIKMALKTGTSILPVTLYNTNNFFIKNIIFNSGLSVYIHVHPLIDVLKLSEYEKENLTSIIRDQ
IVKKLETIKI
>Mature_250_residues
MIIVFMKILRSIITYFNVLLFFLILIFFLFPFYLVCKIFLIERYVVRLSFIMMRACIKISLWLAGIKIIVTGSENIPKKS
NVIIMGNHIAAMDPLIFIYTFACPFVILAKHSLLRIPFVNIVLIVMGVIFVNRRSIRSAAAAEVKAIKVMREGRSIGIFP
EGTRNRGGDTRVFKKGSIKMALKTGTSILPVTLYNTNNFFIKNIIFNSGLSVYIHVHPLIDVLKLSEYEKENLTSIIRDQ
IVKKLETIKI

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family

Homologues:

Organism=Homo sapiens, GI5453718, Length=183, Percent_Identity=26.2295081967213, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI15100175, Length=183, Percent_Identity=26.2295081967213, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI6041665, Length=149, Percent_Identity=30.8724832214765, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1789395, Length=188, Percent_Identity=28.1914893617021, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17564032, Length=249, Percent_Identity=25.3012048192771, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17568319, Length=140, Percent_Identity=27.8571428571429, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320151, Length=204, Percent_Identity=27.4509803921569, Blast_Score=72, Evalue=7e-14,
Organism=Drosophila melanogaster, GI281364648, Length=201, Percent_Identity=26.865671641791, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24582856, Length=201, Percent_Identity=26.865671641791, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24582854, Length=201, Percent_Identity=26.865671641791, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24641614, Length=247, Percent_Identity=28.3400809716599, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24641612, Length=247, Percent_Identity=28.3400809716599, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PLSC_BORBU (Q59188)

Other databases:

- EMBL:   AE000783
- EMBL:   L32861
- PIR:   E70104
- RefSeq:   NP_212171.1
- ProteinModelPortal:   Q59188
- EnsemblBacteria:   EBBORT00000008608
- GeneID:   1194873
- GenomeReviews:   AE000783_GR
- KEGG:   bbu:BB0037
- NMPDR:   fig|224326.1.peg.421
- TIGR:   BB_0037
- GeneTree:   EBGT00050000006883
- HOGENOM:   HBG354607
- OMA:   KAKAPIL
- PhylomeDB:   Q59188
- ProtClustDB:   CLSK507308
- BioCyc:   BBUR224326:BB_0037-MONOMER
- BRENDA:   2.3.1.51
- GO:   GO:0016020
- InterPro:   IPR002123
- InterPro:   IPR004552
- SMART:   SM00563
- TIGRFAMs:   TIGR00530

Pfam domain/function: PF01553 Acyltransferase

EC number: =2.3.1.51

Molecular weight: Translated: 28581; Mature: 28581

Theoretical pI: Translated: 10.83; Mature: 10.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIVFMKILRSIITYFNVLLFFLILIFFLFPFYLVCKIFLIERYVVRLSFIMMRACIKIS
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LWLAGIKIIVTGSENIPKKSNVIIMGNHIAAMDPLIFIYTFACPFVILAKHSLLRIPFVN
HHEECEEEEEECCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
IVLIVMGVIFVNRRSIRSAAAAEVKAIKVMREGRSIGIFPEGTRNRGGDTRVFKKGSIKM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCEEE
ALKTGTSILPVTLYNTNNFFIKNIIFNSGLSVYIHVHPLIDVLKLSEYEKENLTSIIRDQ
EEECCCCEEEEEEEECCCEEEEHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
IVKKLETIKI
HHHHHHHCCC
>Mature Secondary Structure
MIIVFMKILRSIITYFNVLLFFLILIFFLFPFYLVCKIFLIERYVVRLSFIMMRACIKIS
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LWLAGIKIIVTGSENIPKKSNVIIMGNHIAAMDPLIFIYTFACPFVILAKHSLLRIPFVN
HHEECEEEEEECCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
IVLIVMGVIFVNRRSIRSAAAAEVKAIKVMREGRSIGIFPEGTRNRGGDTRVFKKGSIKM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCEEE
ALKTGTSILPVTLYNTNNFFIKNIIFNSGLSVYIHVHPLIDVLKLSEYEKENLTSIIRDQ
EEECCCCEEEEEEEECCCEEEEHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
IVKKLETIKI
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9403685; 7812434