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The map label for this gene is phoP [H]

Identifier: 154687043

GI number: 154687043

Start: 2740474

End: 2741193

Strand: Reverse

Name: phoP [H]

Synonym: RBAM_026150

Alternate gene names: 154687043

Gene position: 2741193-2740474 (Counterclockwise)

Preceding gene: 154687044

Following gene: 154687042

Centisome position: 69.95

GC content: 45.0

Gene sequence:

>720_bases
ATGAACAAAAAAATTTTAGTTGTAGATGATGAACAATCTATCGTTACTCTTTTACAGTATAATCTGGAACGGTCCGGCTA
TGATGTCATTACCGCATCAGACGGTGAAGAGGCTCTGGAGCTGGCAGAGAATGAAAACCCGGATTTAATCGTACTGGATG
TCATGCTGCCAAAAGTGGACGGAATCGACGTCTGTAAGCAGCTCAGACAGCAGAAAATGATGGTTCCAATCTTGATGCTG
ACAGCAAAAGATGAGGAGTTTGATAAAGTGCTGGGACTGGAGCTCGGAGCGGATGATTACATGACAAAGCCGTTCAGTCC
GCGGGAAGTCACTGCGCGGGTGAAAGCCATTTTAAGAAGGGCTGACATTTCTTCGCTGTCACAAGGCAGAGAAGAGGAAA
AGGACGGGCAGATCCTCATCGGCGAGCTGAAAATTCTTCCGGAGCATTACGAAGCGTACTTCAAGTCAGAACAGCTGGAA
TTGACGCCTAAAGAATTTGAACTGCTTCTGTATTTGGGAAAACATAAGGGAAGAGTGCTGACGAGAGATCTTCTGCTGAG
CGCGGTCTGGAACTATGATTTTGCCGGGGATACCCGGATTGTTGACGTTCATATCAGCCATCTGCGCGACAAAATCGAAT
CAAATACCAAAAAACCCATCTATATTAAAACAATCAGAGGTTTGGGGTATAAACTGGAGGAGCCAAAAATGAATGAATAA

Upstream 100 bases:

>100_bases
GAACGGGCAGTATTGGATAAAATGAAATCATAAAGTGATATGCAGCACATAAAATAGAGAAAATTGGATGTCGGGGAAAA
TAGACAGCGGAGGGCGCAGC

Downstream 100 bases:

>100_bases
AGTCCGTGTGCGTCTGTTCGCTTTACTCGTTGTATGTATCATATTGGTTTTCAGTGTTCTCGGCCTTTTTTTACAGCATC
TTATTTCTTCATCCGCTGAA

Product: PhoP

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MNKKILVVDDEQSIVTLLQYNLERSGYDVITASDGEEALELAENENPDLIVLDVMLPKVDGIDVCKQLRQQKMMVPILML
TAKDEEFDKVLGLELGADDYMTKPFSPREVTARVKAILRRADISSLSQGREEEKDGQILIGELKILPEHYEAYFKSEQLE
LTPKEFELLLYLGKHKGRVLTRDLLLSAVWNYDFAGDTRIVDVHISHLRDKIESNTKKPIYIKTIRGLGYKLEEPKMNE

Sequences:

>Translated_239_residues
MNKKILVVDDEQSIVTLLQYNLERSGYDVITASDGEEALELAENENPDLIVLDVMLPKVDGIDVCKQLRQQKMMVPILML
TAKDEEFDKVLGLELGADDYMTKPFSPREVTARVKAILRRADISSLSQGREEEKDGQILIGELKILPEHYEAYFKSEQLE
LTPKEFELLLYLGKHKGRVLTRDLLLSAVWNYDFAGDTRIVDVHISHLRDKIESNTKKPIYIKTIRGLGYKLEEPKMNE
>Mature_239_residues
MNKKILVVDDEQSIVTLLQYNLERSGYDVITASDGEEALELAENENPDLIVLDVMLPKVDGIDVCKQLRQQKMMVPILML
TAKDEEFDKVLGLELGADDYMTKPFSPREVTARVKAILRRADISSLSQGREEEKDGQILIGELKILPEHYEAYFKSEQLE
LTPKEFELLLYLGKHKGRVLTRDLLLSAVWNYDFAGDTRIVDVHISHLRDKIESNTKKPIYIKTIRGLGYKLEEPKMNE

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=39.7379912663755, Blast_Score=170, Evalue=7e-44,
Organism=Escherichia coli, GI1786599, Length=234, Percent_Identity=40.1709401709402, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=44.2982456140351, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1788394, Length=233, Percent_Identity=39.4849785407725, Blast_Score=161, Evalue=4e-41,
Organism=Escherichia coli, GI1786784, Length=232, Percent_Identity=39.2241379310345, Blast_Score=154, Evalue=5e-39,
Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=40.8695652173913, Blast_Score=151, Evalue=3e-38,
Organism=Escherichia coli, GI1790552, Length=232, Percent_Identity=36.6379310344828, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1789402, Length=231, Percent_Identity=34.6320346320346, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI87082012, Length=233, Percent_Identity=35.1931330472103, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1786911, Length=229, Percent_Identity=34.9344978165939, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=34.9344978165939, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=34.9344978165939, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1787229, Length=233, Percent_Identity=31.3304721030043, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1787375, Length=230, Percent_Identity=30.8695652173913, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1788550, Length=103, Percent_Identity=33.9805825242718, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1790299, Length=111, Percent_Identity=34.2342342342342, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790437, Length=104, Percent_Identity=38.4615384615385, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1787487, Length=104, Percent_Identity=32.6923076923077, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1788713, Length=103, Percent_Identity=34.9514563106796, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI145693157, Length=102, Percent_Identity=34.3137254901961, Blast_Score=60, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27394; Mature: 27394

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKILVVDDEQSIVTLLQYNLERSGYDVITASDGEEALELAENENPDLIVLDVMLPKVD
CCCCEEEEECCHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHCCCCCCEEEEEEECCCCC
GIDVCKQLRQQKMMVPILMLTAKDEEFDKVLGLELGADDYMTKPFSPREVTARVKAILRR
CHHHHHHHHHHHHHCEEEEEEECCHHHHHHHCCEECCCCCCCCCCCCHHHHHHHHHHHHH
ADISSLSQGREEEKDGQILIGELKILPEHYEAYFKSEQLELTPKEFELLLYLGKHKGRVL
HHHHHHHCCCCCCCCCCEEEEEEEECHHHHHHHHCCCCEEECHHHEEEEEEECCCCCCCH
TRDLLLSAVWNYDFAGDTRIVDVHISHLRDKIESNTKKPIYIKTIRGLGYKLEEPKMNE
HHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHCCCCCCEEEEEECCCCEEECCCCCCC
>Mature Secondary Structure
MNKKILVVDDEQSIVTLLQYNLERSGYDVITASDGEEALELAENENPDLIVLDVMLPKVD
CCCCEEEEECCHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHCCCCCCEEEEEEECCCCC
GIDVCKQLRQQKMMVPILMLTAKDEEFDKVLGLELGADDYMTKPFSPREVTARVKAILRR
CHHHHHHHHHHHHHCEEEEEEECCHHHHHHHCCEECCCCCCCCCCCCHHHHHHHHHHHHH
ADISSLSQGREEEKDGQILIGELKILPEHYEAYFKSEQLELTPKEFELLLYLGKHKGRVL
HHHHHHHCCCCCCCCCCEEEEEEEECHHHHHHHHCCCCEEECHHHEEEEEEECCCCCCCH
TRDLLLSAVWNYDFAGDTRIVDVHISHLRDKIESNTKKPIYIKTIRGLGYKLEEPKMNE
HHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHCCCCCCEEEEEECCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]