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The map label for this gene is phoR [H]

Identifier: 154687042

GI number: 154687042

Start: 2738742

End: 2740481

Strand: Reverse

Name: phoR [H]

Synonym: RBAM_026140

Alternate gene names: 154687042

Gene position: 2740481-2738742 (Counterclockwise)

Preceding gene: 154687043

Following gene: 154687041

Centisome position: 69.94

GC content: 49.02

Gene sequence:

>1740_bases
ATGAATAAAGTCCGTGTGCGTCTGTTCGCTTTACTCGTTGTATGTATCATATTGGTTTTCAGTGTTCTCGGCCTTTTTTT
ACAGCATCTTATTTCTTCATCCGCTGAAGAAAGAACGGCGGATCAGCTGAAAAAGGAATCGGTATACATAGCGGGCCTTC
TTGACACCGGCCGAATCGGCAATAAAAGCAATGAAACGGTGATTCGTGACGCCGGCCGCACCCTCGGTATAAACGTCGCC
GTGCTCAACGAGAAGGGTGACGCCGTATATCATTCCGGCAGTCGTGCTGATGATTCAGCCGTAAAGGAGTTCATTTCTCA
CAATAAAAGCGAGGAAGCCGTACAGTCGAAAAGCAAAGTCATCCGCGGCACTGCCGTAAAAAATGACGCCGGGAAAATTG
CGGGGTATGTACTCGTTTCCTCTGAGATCAACGGCGGTTCAAGCGTTACCGGAGAAATGTGGGGCATGCTGGCAGCAAGT
CTTTGTACCGCTTTTATCATTATCGTTTTCTTTTATACAAACATGACGTCCCGTTACAAAAAATCAATCGACGCCGCGAC
AAAAGTGGCGACGGAGCTGTCCAAGGGGAATTATGACGCCCGCTCCTACAGCGGTTACGCAAGGCGGTCGGACCGTCTCG
GGCGTGCGATGAACAGTCTGGCGGTCGATTTAATGGAAATGACGAGAACGCAGGATATGCAGCGCGATCGTCTGTTAACC
GTCATTGAAAATATCGGATCCGGTTTGATTTTAATAGACGGGAGAGGTTTTATCAATCTCGTGAACCGGTCATACACGAA
GCAGTTTCATACAAAGCCTGAACGTCTGCTTCGGCGCCTTTACCATGATGCGTTTGAACATGAGGAGATCATTCGGCTTG
TCGAAGACATTTTTATGACGGAGACGAAAAAATGCCAGCTGCTCAGACTTCCCATCAACATTGAGCGGCGCTACTTTGAA
GTTGACGGCGTTCCGATCATGGGCCCTGACGATGAATGGAAGGGCATCGTCCTCGTCTTTCACGATATGACGGAAATTAA
AAAATTGGAGCAGATGAGAAAGGACTTCGTCGCCAATGTCTCCCATGAACTGAAAACACCGATCACCTCGATTAAAGGCT
TTACGGAAACACTGTTAGACGGAGCGATGAAAGACGAAAAGGCGCTTTCAGACTTTCTGTCTATTATTCTGAAAGAAAGT
GAGCGGCTCCAATCTCTCGTGCAGGATTTACTGGATTTATCCAAGATGGAGCAGCAAAACTTTACGATGCGCGTAGAGTC
CTTTGACGCCGCAAAAATTCTGCATGAAATTGAAGCGCTTTTGCGGCATAAGGCTGAGGAAAAAGGCATCAGCTTTCAGC
TCGATCTCCCGGAAGAGCCGATTTTTGTGACGGGTGACGCGCACAGGCTGAAGCAGGTATTTTTGAATCTGGCGAACAAT
GCCCTGACCTACACGCCTGAAAAAGGGACGGTGGGGATTTCGGTACATGTGAAAGAAACCGTTGTCGATATCAAAGTGTC
CGATACGGGAATCGGCATTCAGAAGGAAGAGATCCCGCGGATATTTGAGAGATTCTACCGCGTGGATAAAGACAGAAGCC
GCAACTCGGGAGGAACCGGGCTCGGCCTCGCCATCGTGAAGCACTTAATAGAAGCCCATGAAGGTAAAATCGAGGTCACA
AGCGAGCCGGGACAGGGGACTGTATTTACCGTGACGCTGAAGCGGCAGCCGGAAGCGTGA

Upstream 100 bases:

>100_bases
ATCAGCCATCTGCGCGACAAAATCGAATCAAATACCAAAAAACCCATCTATATTAAAACAATCAGAGGTTTGGGGTATAA
ACTGGAGGAGCCAAAAATGA

Downstream 100 bases:

>100_bases
CCAGCTTTACAAAGGATTAACAATTTCTTCATGACCTGTTAAACCTATCTTGTTAGGATATAACAGAACCCCTTCATCCA
AGGAGCCAATTTTGACGGCG

Product: PhoR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 579; Mature: 579

Protein sequence:

>579_residues
MNKVRVRLFALLVVCIILVFSVLGLFLQHLISSSAEERTADQLKKESVYIAGLLDTGRIGNKSNETVIRDAGRTLGINVA
VLNEKGDAVYHSGSRADDSAVKEFISHNKSEEAVQSKSKVIRGTAVKNDAGKIAGYVLVSSEINGGSSVTGEMWGMLAAS
LCTAFIIIVFFYTNMTSRYKKSIDAATKVATELSKGNYDARSYSGYARRSDRLGRAMNSLAVDLMEMTRTQDMQRDRLLT
VIENIGSGLILIDGRGFINLVNRSYTKQFHTKPERLLRRLYHDAFEHEEIIRLVEDIFMTETKKCQLLRLPINIERRYFE
VDGVPIMGPDDEWKGIVLVFHDMTEIKKLEQMRKDFVANVSHELKTPITSIKGFTETLLDGAMKDEKALSDFLSIILKES
ERLQSLVQDLLDLSKMEQQNFTMRVESFDAAKILHEIEALLRHKAEEKGISFQLDLPEEPIFVTGDAHRLKQVFLNLANN
ALTYTPEKGTVGISVHVKETVVDIKVSDTGIGIQKEEIPRIFERFYRVDKDRSRNSGGTGLGLAIVKHLIEAHEGKIEVT
SEPGQGTVFTVTLKRQPEA

Sequences:

>Translated_579_residues
MNKVRVRLFALLVVCIILVFSVLGLFLQHLISSSAEERTADQLKKESVYIAGLLDTGRIGNKSNETVIRDAGRTLGINVA
VLNEKGDAVYHSGSRADDSAVKEFISHNKSEEAVQSKSKVIRGTAVKNDAGKIAGYVLVSSEINGGSSVTGEMWGMLAAS
LCTAFIIIVFFYTNMTSRYKKSIDAATKVATELSKGNYDARSYSGYARRSDRLGRAMNSLAVDLMEMTRTQDMQRDRLLT
VIENIGSGLILIDGRGFINLVNRSYTKQFHTKPERLLRRLYHDAFEHEEIIRLVEDIFMTETKKCQLLRLPINIERRYFE
VDGVPIMGPDDEWKGIVLVFHDMTEIKKLEQMRKDFVANVSHELKTPITSIKGFTETLLDGAMKDEKALSDFLSIILKES
ERLQSLVQDLLDLSKMEQQNFTMRVESFDAAKILHEIEALLRHKAEEKGISFQLDLPEEPIFVTGDAHRLKQVFLNLANN
ALTYTPEKGTVGISVHVKETVVDIKVSDTGIGIQKEEIPRIFERFYRVDKDRSRNSGGTGLGLAIVKHLIEAHEGKIEVT
SEPGQGTVFTVTLKRQPEA
>Mature_579_residues
MNKVRVRLFALLVVCIILVFSVLGLFLQHLISSSAEERTADQLKKESVYIAGLLDTGRIGNKSNETVIRDAGRTLGINVA
VLNEKGDAVYHSGSRADDSAVKEFISHNKSEEAVQSKSKVIRGTAVKNDAGKIAGYVLVSSEINGGSSVTGEMWGMLAAS
LCTAFIIIVFFYTNMTSRYKKSIDAATKVATELSKGNYDARSYSGYARRSDRLGRAMNSLAVDLMEMTRTQDMQRDRLLT
VIENIGSGLILIDGRGFINLVNRSYTKQFHTKPERLLRRLYHDAFEHEEIIRLVEDIFMTETKKCQLLRLPINIERRYFE
VDGVPIMGPDDEWKGIVLVFHDMTEIKKLEQMRKDFVANVSHELKTPITSIKGFTETLLDGAMKDEKALSDFLSIILKES
ERLQSLVQDLLDLSKMEQQNFTMRVESFDAAKILHEIEALLRHKAEEKGISFQLDLPEEPIFVTGDAHRLKQVFLNLANN
ALTYTPEKGTVGISVHVKETVVDIKVSDTGIGIQKEEIPRIFERFYRVDKDRSRNSGGTGLGLAIVKHLIEAHEGKIEVT
SEPGQGTVFTVTLKRQPEA

Specific function: Member of the two-component regulatory system phoP/phoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates phoP in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=294, Percent_Identity=34.0136054421769, Blast_Score=159, Evalue=7e-40,
Organism=Escherichia coli, GI1788393, Length=231, Percent_Identity=34.6320346320346, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI1786783, Length=252, Percent_Identity=33.7301587301587, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1789149, Length=225, Percent_Identity=33.3333333333333, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI48994928, Length=266, Percent_Identity=33.4586466165414, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI145693157, Length=226, Percent_Identity=33.6283185840708, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI1790346, Length=235, Percent_Identity=32.3404255319149, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1788549, Length=379, Percent_Identity=25.065963060686, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1788713, Length=229, Percent_Identity=31.8777292576419, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1790861, Length=239, Percent_Identity=29.7071129707113, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI87081816, Length=232, Percent_Identity=31.0344827586207, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790436, Length=235, Percent_Identity=29.3617021276596, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1786912, Length=229, Percent_Identity=29.2576419213974, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI87082128, Length=231, Percent_Identity=29.8701298701299, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788279, Length=235, Percent_Identity=27.2340425531915, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1790300, Length=244, Percent_Identity=30.327868852459, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1789808, Length=229, Percent_Identity=29.2576419213974, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1787894, Length=237, Percent_Identity=27.0042194092827, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI1789403, Length=206, Percent_Identity=29.6116504854369, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1787374, Length=223, Percent_Identity=28.2511210762332, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1790551, Length=227, Percent_Identity=27.3127753303965, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790567, Length=346, Percent_Identity=24.8554913294798, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 64923; Mature: 64923

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKVRVRLFALLVVCIILVFSVLGLFLQHLISSSAEERTADQLKKESVYIAGLLDTGRIG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEEEEECCCCCC
NKSNETVIRDAGRTLGINVAVLNEKGDAVYHSGSRADDSAVKEFISHNKSEEAVQSKSKV
CCCCCCCEECCCCEEEEEEEEEECCCCEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHH
IRGTAVKNDAGKIAGYVLVSSEINGGSSVTGEMWGMLAASLCTAFIIIVFFYTNMTSRYK
HCCCCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KSIDAATKVATELSKGNYDARSYSGYARRSDRLGRAMNSLAVDLMEMTRTQDMQRDRLLT
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIENIGSGLILIDGRGFINLVNRSYTKQFHTKPERLLRRLYHDAFEHEEIIRLVEDIFMT
HHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ETKKCQLLRLPINIERRYFEVDGVPIMGPDDEWKGIVLVFHDMTEIKKLEQMRKDFVANV
CCCCCEEEECCCCCCEEEEEECCEEEECCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHH
SHELKTPITSIKGFTETLLDGAMKDEKALSDFLSIILKESERLQSLVQDLLDLSKMEQQN
HHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
FTMRVESFDAAKILHEIEALLRHKAEEKGISFQLDLPEEPIFVTGDAHRLKQVFLNLANN
CEEEECCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEECCHHHHHHHHHHHHCC
ALTYTPEKGTVGISVHVKETVVDIKVSDTGIGIQKEEIPRIFERFYRVDKDRSRNSGGTG
CEEECCCCCEEEEEEEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCH
LGLAIVKHLIEAHEGKIEVTSEPGQGTVFTVTLKRQPEA
HHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEECCCCCC
>Mature Secondary Structure
MNKVRVRLFALLVVCIILVFSVLGLFLQHLISSSAEERTADQLKKESVYIAGLLDTGRIG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEEEEECCCCCC
NKSNETVIRDAGRTLGINVAVLNEKGDAVYHSGSRADDSAVKEFISHNKSEEAVQSKSKV
CCCCCCCEECCCCEEEEEEEEEECCCCEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHH
IRGTAVKNDAGKIAGYVLVSSEINGGSSVTGEMWGMLAASLCTAFIIIVFFYTNMTSRYK
HCCCCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KSIDAATKVATELSKGNYDARSYSGYARRSDRLGRAMNSLAVDLMEMTRTQDMQRDRLLT
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIENIGSGLILIDGRGFINLVNRSYTKQFHTKPERLLRRLYHDAFEHEEIIRLVEDIFMT
HHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ETKKCQLLRLPINIERRYFEVDGVPIMGPDDEWKGIVLVFHDMTEIKKLEQMRKDFVANV
CCCCCEEEECCCCCCEEEEEECCEEEECCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHH
SHELKTPITSIKGFTETLLDGAMKDEKALSDFLSIILKESERLQSLVQDLLDLSKMEQQN
HHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
FTMRVESFDAAKILHEIEALLRHKAEEKGISFQLDLPEEPIFVTGDAHRLKQVFLNLANN
CEEEECCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEECCHHHHHHHHHHHHCC
ALTYTPEKGTVGISVHVKETVVDIKVSDTGIGIQKEEIPRIFERFYRVDKDRSRNSGGTG
CEEECCCCCEEEEEEEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCH
LGLAIVKHLIEAHEGKIEVTSEPGQGTVFTVTLKRQPEA
HHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3142862; 9387221; 9384377 [H]