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The map label for this gene is sdhB [H]

Identifier: 154686978

GI number: 154686978

Start: 2668986

End: 2669744

Strand: Reverse

Name: sdhB [H]

Synonym: RBAM_025500

Alternate gene names: 154686978

Gene position: 2669744-2668986 (Counterclockwise)

Preceding gene: 154686979

Following gene: 154686977

Centisome position: 68.13

GC content: 50.72

Gene sequence:

>759_bases
ATGAGTGAGAAAAAGATACGGTTTATCATTACACGTCAGGATACGCCCGAAAGCGCGCCATACGATGAAGAATTCGAAAT
CAATTACCGCCCGAACCTGAACGTGATTTCCGCCCTGATGGAAATCCGCAGAAATCCCGTGAATGCAAAAGGAGAGAAAA
CCACTCCGGTCGCATGGGACATGAACTGTCTTGAAGAAGTATGCGGCGCCTGCTCCATGGTCATCAACGGAAGACCGCGC
CAGTCATGTACGGCGCTGATTGATAAGCTGGAACAGCCGATCCGTCTGAAGCCGATGAAAACATTCCCGGTTGTCCGTGA
CCTTCAGGTTGACCGCAGCAGAATGTTTGATTCACTGAAAAAAGTGAAAGCATGGGTGCCGATTGACGGAACTTACGATT
TGGGGCCGGGGCCGAGAATGCCGGAAAAACGCCGCCAGTGGGCATATGAATTGTCTAAATGCATGACATGCGGCGTCTGC
CTCGAAGCCTGCCCGAACGTCAACAGCAAGTCGAAATTCATGGGGCCTGCCCCGATGTCGCAAGTTCGTCTGTTTAACGC
CCATCCGACGGGTGCGATGAACAAAGCAGAACGTTTAGAAGCGTTAATGACAGACGGCGGCCTCGGAGATTGCGGGAATT
CACAAAACTGTGTTCAATCCTGCCCGAAAGGCATTCCGCTTACGACTTCAATCGCCGCTTTGAACAGAGATACCAATTTA
CAAGCATTCCGTAATTTCTTCGGAAGCGACAGAGTATAA

Upstream 100 bases:

>100_bases
GTCCGTTTGAAGCTCCGGAATTTGAATATCAGGATGTCGATGTATCACTGATTGCGCCCCGTAAACGCGACTACTCGAAG
AAGAAGGTGGCGAAATAATC

Downstream 100 bases:

>100_bases
GAAAGAGAAAAAGAGCCTCTTCCGCACGGGAGAGGTTTTTTTATAAGGAGCTGAAGGTGATGAAACAACCGCAATATATT
GATATCCCGTTTGAAGAATG

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MSEKKIRFIITRQDTPESAPYDEEFEINYRPNLNVISALMEIRRNPVNAKGEKTTPVAWDMNCLEEVCGACSMVINGRPR
QSCTALIDKLEQPIRLKPMKTFPVVRDLQVDRSRMFDSLKKVKAWVPIDGTYDLGPGPRMPEKRRQWAYELSKCMTCGVC
LEACPNVNSKSKFMGPAPMSQVRLFNAHPTGAMNKAERLEALMTDGGLGDCGNSQNCVQSCPKGIPLTTSIAALNRDTNL
QAFRNFFGSDRV

Sequences:

>Translated_252_residues
MSEKKIRFIITRQDTPESAPYDEEFEINYRPNLNVISALMEIRRNPVNAKGEKTTPVAWDMNCLEEVCGACSMVINGRPR
QSCTALIDKLEQPIRLKPMKTFPVVRDLQVDRSRMFDSLKKVKAWVPIDGTYDLGPGPRMPEKRRQWAYELSKCMTCGVC
LEACPNVNSKSKFMGPAPMSQVRLFNAHPTGAMNKAERLEALMTDGGLGDCGNSQNCVQSCPKGIPLTTSIAALNRDTNL
QAFRNFFGSDRV
>Mature_251_residues
SEKKIRFIITRQDTPESAPYDEEFEINYRPNLNVISALMEIRRNPVNAKGEKTTPVAWDMNCLEEVCGACSMVINGRPRQ
SCTALIDKLEQPIRLKPMKTFPVVRDLQVDRSRMFDSLKKVKAWVPIDGTYDLGPGPRMPEKRRQWAYELSKCMTCGVCL
EACPNVNSKSKFMGPAPMSQVRLFNAHPTGAMNKAERLEALMTDGGLGDCGNSQNCVQSCPKGIPLTTSIAALNRDTNLQ
AFRNFFGSDRV

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=238, Percent_Identity=26.890756302521, Blast_Score=75, Evalue=4e-14,
Organism=Escherichia coli, GI1790596, Length=234, Percent_Identity=25.6410256410256, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1786943, Length=241, Percent_Identity=27.3858921161826, Blast_Score=81, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17533915, Length=218, Percent_Identity=22.9357798165138, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322987, Length=235, Percent_Identity=25.531914893617, Blast_Score=76, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24643156, Length=227, Percent_Identity=26.431718061674, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17137106, Length=239, Percent_Identity=25.1046025104602, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 28242; Mature: 28111

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
9.1 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
8.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKKIRFIITRQDTPESAPYDEEFEINYRPNLNVISALMEIRRNPVNAKGEKTTPVAWD
CCCCEEEEEEEECCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCEEEC
MNCLEEVCGACSMVINGRPRQSCTALIDKLEQPIRLKPMKTFPVVRDLQVDRSRMFDSLK
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHHH
KVKAWVPIDGTYDLGPGPRMPEKRRQWAYELSKCMTCGVCLEACPNVNSKSKFMGPAPMS
HHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
QVRLFNAHPTGAMNKAERLEALMTDGGLGDCGNSQNCVQSCPKGIPLTTSIAALNRDTNL
HEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHCCCCCH
QAFRNFFGSDRV
HHHHHHHCCCCC
>Mature Secondary Structure 
SEKKIRFIITRQDTPESAPYDEEFEINYRPNLNVISALMEIRRNPVNAKGEKTTPVAWD
CCCEEEEEEEECCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCEEEC
MNCLEEVCGACSMVINGRPRQSCTALIDKLEQPIRLKPMKTFPVVRDLQVDRSRMFDSLK
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHHH
KVKAWVPIDGTYDLGPGPRMPEKRRQWAYELSKCMTCGVCLEACPNVNSKSKFMGPAPMS
HHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
QVRLFNAHPTGAMNKAERLEALMTDGGLGDCGNSQNCVQSCPKGIPLTTSIAALNRDTNL
HEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHCCCCCH
QAFRNFFGSDRV
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3027051; 8969504; 9384377; 3114423 [H]