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The map label for this gene is clpX [H]

Identifier: 154686958

GI number: 154686958

Start: 2649334

End: 2650596

Strand: Reverse

Name: clpX [H]

Synonym: RBAM_025280

Alternate gene names: 154686958

Gene position: 2650596-2649334 (Counterclockwise)

Preceding gene: 154686959

Following gene: 154686957

Centisome position: 67.64

GC content: 45.53

Gene sequence:

>1263_bases
ATGTTTAAATTCAACGAGGAAAAAGGACAATTGAAATGCTCGTTCTGCGGAAAAACGCAAGATCAGGTTCGTAAGCTGGT
TGCAGGACCGGGTGTATATATATGCGACGAATGTATTGAGCTCTGTACAGAAATCGTAGAGGAAGAGCTCGGTACAGAAG
AAGAAGTCGAATTTAAAGACGTTCCGAAGCCGCAGGAAATCCGTGAGATTCTGAATGAATATGTCATCGGACAGGATCAG
GCGAAGAAATCACTTGCGGTTGCGGTATACAACCATTACAAACGCATCAACTCCAACAGTAAAGTGGATGATGTCGAGCT
TTCTAAAAGTAATATTTCTTTAATCGGACCGACTGGAAGCGGGAAAACACTTCTTGCCCAGACGCTTGCGCGTATTCTGA
ACGTGCCGTTTGCGATCGCGGACGCTACATCTCTGACTGAAGCCGGATATGTCGGTGAGGACGTAGAAAACATCCTCCTC
AAGCTGATTCAGGCAGCAGACTATGATGTGGAAAAAGCAGAAAAAGGCATTATTTATATCGATGAAATCGATAAAGTAGC
GCGAAAATCTGAAAACCCATCCATTACACGCGACGTATCAGGCGAAGGCGTTCAGCAGGCGTTGCTGAAAATTCTTGAAG
GAACGGTTGCAAGCGTGCCGCCTCAAGGAGGACGCAAACATCCTCATCAGGAATTCATCCAGATCGATACGACGAATATT
CTGTTCATTTGCGGCGGTGCATTTGACGGCATTGAACAAATTATCAAACGCCGTCTCGGACAAAAAGTCATCGGTTTCGG
CTCAGATAATAAAGCGGCAGACCTTGAAAAAGAAGAACTGCTTTCTAAAGTTCTTCCGGAAGACTTGCTCCGTTTCGGTC
TGATTCCTGAATTCATCGGCCGTCTTCCTGTCATTGCAAGCCTTGAGCAGCTTGACGAAACGGCACTGGTTGAAATTCTG
ACTAAACCGAAAAACGCACTCGTCAAACAATACAAGAAAATGTTAGAACTTGATGATGTCGAGCTTGAATTTGAAGACGA
GGCATTATCTGAAATTGCGAAAAAAGCGATCGAGCGTAAAACAGGCGCACGCGGCCTGCGTTCTATCATTGAAGGCATCA
TGCTTGACGTCATGTTTGATCTGCCGTCCCGCGATGATATTGAAAAATGTGTCATTACCGGAGCGACAGTCGCAGACGGT
GAAGCACCGCGTCTTGTATTAAAAGACGGCACAGTTGTCGGCCAAGATAAAACATCAGCATAA

Upstream 100 bases:

>100_bases
AAGTATGGTAAAATGCAATACATACTCGATCGTAGCAAGAACCGTTTTCTTTTGCCCTTCAGGTAAAAGAAAAAGTGAGA
CAAGATTAAGGGGTGAAAGA

Downstream 100 bases:

>100_bases
CATGACAAAACCTCCTGACTCGAATCGATCAGGAGGTTTTTTTCTTGTCCTGACCCTTCTGAAAATGTTTATTCCGGGCT
TTGCTGGGAGATACTAGCGG

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MFKFNEEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGTEEEVEFKDVPKPQEIREILNEYVIGQDQ
AKKSLAVAVYNHYKRINSNSKVDDVELSKSNISLIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILL
KLIQAADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNI
LFICGGAFDGIEQIIKRRLGQKVIGFGSDNKAADLEKEELLSKVLPEDLLRFGLIPEFIGRLPVIASLEQLDETALVEIL
TKPKNALVKQYKKMLELDDVELEFEDEALSEIAKKAIERKTGARGLRSIIEGIMLDVMFDLPSRDDIEKCVITGATVADG
EAPRLVLKDGTVVGQDKTSA

Sequences:

>Translated_420_residues
MFKFNEEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGTEEEVEFKDVPKPQEIREILNEYVIGQDQ
AKKSLAVAVYNHYKRINSNSKVDDVELSKSNISLIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILL
KLIQAADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNI
LFICGGAFDGIEQIIKRRLGQKVIGFGSDNKAADLEKEELLSKVLPEDLLRFGLIPEFIGRLPVIASLEQLDETALVEIL
TKPKNALVKQYKKMLELDDVELEFEDEALSEIAKKAIERKTGARGLRSIIEGIMLDVMFDLPSRDDIEKCVITGATVADG
EAPRLVLKDGTVVGQDKTSA
>Mature_420_residues
MFKFNEEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGTEEEVEFKDVPKPQEIREILNEYVIGQDQ
AKKSLAVAVYNHYKRINSNSKVDDVELSKSNISLIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILL
KLIQAADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNI
LFICGGAFDGIEQIIKRRLGQKVIGFGSDNKAADLEKEELLSKVLPEDLLRFGLIPEFIGRLPVIASLEQLDETALVEIL
TKPKNALVKQYKKMLELDDVELEFEDEALSEIAKKAIERKTGARGLRSIIEGIMLDVMFDLPSRDDIEKCVITGATVADG
EAPRLVLKDGTVVGQDKTSA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=328, Percent_Identity=50, Blast_Score=315, Evalue=7e-86,
Organism=Escherichia coli, GI1786642, Length=401, Percent_Identity=64.8379052369077, Blast_Score=528, Evalue=1e-151,
Organism=Escherichia coli, GI1790366, Length=103, Percent_Identity=44.6601941747573, Blast_Score=96, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71982908, Length=307, Percent_Identity=47.557003257329, Blast_Score=283, Evalue=1e-76,
Organism=Caenorhabditis elegans, GI71982905, Length=299, Percent_Identity=48.1605351170569, Blast_Score=283, Evalue=1e-76,
Organism=Caenorhabditis elegans, GI71988663, Length=435, Percent_Identity=38.3908045977011, Blast_Score=266, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI71988660, Length=260, Percent_Identity=39.6153846153846, Blast_Score=179, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6319704, Length=434, Percent_Identity=38.4792626728111, Blast_Score=258, Evalue=9e-70,
Organism=Drosophila melanogaster, GI24648289, Length=318, Percent_Identity=50, Blast_Score=306, Evalue=1e-83,
Organism=Drosophila melanogaster, GI24648291, Length=318, Percent_Identity=50, Blast_Score=306, Evalue=2e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46248; Mature: 46248

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKFNEEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGTEEEVEFKD
CCCCCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VPKPQEIREILNEYVIGQDQAKKSLAVAVYNHYKRINSNSKVDDVELSKSNISLIGPTGS
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCEEEECCCCC
GKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAEKGIIYI
CHHHHHHHHHHHHCCCHHHHCCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCEEEE
DEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNI
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCHHHHEEECCCEE
LFICGGAFDGIEQIIKRRLGQKVIGFGSDNKAADLEKEELLSKVLPEDLLRFGLIPEFIG
EEEECCCHHHHHHHHHHHHCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHC
RLPVIASLEQLDETALVEILTKPKNALVKQYKKMLELDDVELEFEDEALSEIAKKAIERK
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHH
TGARGLRSIIEGIMLDVMFDLPSRDDIEKCVITGATVADGEAPRLVLKDGTVVGQDKTSA
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCEECCCCCCEEEEECCEEECCCCCCC
>Mature Secondary Structure
MFKFNEEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGTEEEVEFKD
CCCCCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VPKPQEIREILNEYVIGQDQAKKSLAVAVYNHYKRINSNSKVDDVELSKSNISLIGPTGS
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCEEEECCCCC
GKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAEKGIIYI
CHHHHHHHHHHHHCCCHHHHCCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCEEEE
DEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNI
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCHHHHEEECCCEE
LFICGGAFDGIEQIIKRRLGQKVIGFGSDNKAADLEKEELLSKVLPEDLLRFGLIPEFIG
EEEECCCHHHHHHHHHHHHCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHC
RLPVIASLEQLDETALVEILTKPKNALVKQYKKMLELDDVELEFEDEALSEIAKKAIERK
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHH
TGARGLRSIIEGIMLDVMFDLPSRDDIEKCVITGATVADGEAPRLVLKDGTVVGQDKTSA
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCEECCCCCCEEEEECCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA