Click here to switch to the map view.

The map label for this gene is hemX [H]

Identifier: 154686952

GI number: 154686952

Start: 2641494

End: 2642324

Strand: Reverse

Name: hemX [H]

Synonym: RBAM_025220

Alternate gene names: 154686952

Gene position: 2642324-2641494 (Counterclockwise)

Preceding gene: 154686953

Following gene: 154686951

Centisome position: 67.43

GC content: 41.88

Gene sequence:

>831_bases
ATGATTGATACAGCAATGGCAAGACTTAATGAAGCGACAATTGTTATTTATGCAGTAAGCGTCCTTTTTTACTTTATAGA
TTTTCTTCAACACAACCGGAAGGCTGGGAAAATGGCCTTCTGGTTGCTTTCTATTGTCTGGACTCTGCAAACCGTCTATC
TTTCTTATTTCATGTGGCAGACGGGCAGATTTCCGGTCTTGAATATTACAGAGGCCCTTTACTTTTATGCGTGGGTGCTT
GTCACGCTCTCACTTGTGGTCACGCAGATTCTGCGCGTTGATTTTATCGTGTTTTTCACGAATGTCATCGGTTTCTCGAT
GATTGCGATCCATACGTTTTCACCGACGGATCAGCATTCGGCCGCTTTTTCCGGCCAGCTGGTCTCAGAGCTTTTGGTCA
TTCATATTACAATGGCGATTCTGTCTTACGGCGCTTTTTCCCTTTCTTTTGTCTTTTCGCTTCTTTATCAGTTTCAATAT
TCTTTATTAAAGAAGAAAAAGTGGGGAAAATGGCTGTTGAGAATTGAAGATTTGTCAAAACTTGATTATATGGCTTACGT
TTTAAATGTCATCGGGGTTCCGATGCTGCTGTTGAGCCTGATATTAGGCGTGATCTGGGCGTATGTGTCGCTGGAAACGC
TGTACTGGTTTGATTCAAAAGTGCTCGGTTCGTTTATTGTGCTGCTTTTATACAGCTACTATTTATATATCAGAATGATT
AAGGAACTGCAGGGAAAAGTGGCGGCGTTATGGAATTCAGCATGTTTTCTCGTGCTGATGATTAATTACTTCCTGCTCGG
AAGCCTGTCGCAATTCCATTGGTTCAGTTAA

Upstream 100 bases:

>100_bases
CAGCTGGACAAAAGCCTGGATAACCGCCAGACGGTTCATTCGTTTCAAAAGGCAGAAGCAAAAACGGGCTTACGTCCGCT
TGTAAGTGAGTGAGGGCTGT

Downstream 100 bases:

>100_bases
CGCACGCGCCCAAACAGATTCGGGAGGAAAGAAAATGAGAACGATTAAGGTAGGTTCCAGACGGAGCAAACTGGCTATGA
CCCAGACAAAATGGGTGATT

Product: HemX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MIDTAMARLNEATIVIYAVSVLFYFIDFLQHNRKAGKMAFWLLSIVWTLQTVYLSYFMWQTGRFPVLNITEALYFYAWVL
VTLSLVVTQILRVDFIVFFTNVIGFSMIAIHTFSPTDQHSAAFSGQLVSELLVIHITMAILSYGAFSLSFVFSLLYQFQY
SLLKKKKWGKWLLRIEDLSKLDYMAYVLNVIGVPMLLLSLILGVIWAYVSLETLYWFDSKVLGSFIVLLLYSYYLYIRMI
KELQGKVAALWNSACFLVLMINYFLLGSLSQFHWFS

Sequences:

>Translated_276_residues
MIDTAMARLNEATIVIYAVSVLFYFIDFLQHNRKAGKMAFWLLSIVWTLQTVYLSYFMWQTGRFPVLNITEALYFYAWVL
VTLSLVVTQILRVDFIVFFTNVIGFSMIAIHTFSPTDQHSAAFSGQLVSELLVIHITMAILSYGAFSLSFVFSLLYQFQY
SLLKKKKWGKWLLRIEDLSKLDYMAYVLNVIGVPMLLLSLILGVIWAYVSLETLYWFDSKVLGSFIVLLLYSYYLYIRMI
KELQGKVAALWNSACFLVLMINYFLLGSLSQFHWFS
>Mature_276_residues
MIDTAMARLNEATIVIYAVSVLFYFIDFLQHNRKAGKMAFWLLSIVWTLQTVYLSYFMWQTGRFPVLNITEALYFYAWVL
VTLSLVVTQILRVDFIVFFTNVIGFSMIAIHTFSPTDQHSAAFSGQLVSELLVIHITMAILSYGAFSLSFVFSLLYQFQY
SLLKKKKWGKWLLRIEDLSKLDYMAYVLNVIGVPMLLLSLILGVIWAYVSLETLYWFDSKVLGSFIVLLLYSYYLYIRMI
KELQGKVAALWNSACFLVLMINYFLLGSLSQFHWFS

Specific function: Required for hemL synthesis [H]

COG id: COG0755

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.leprae U1620K [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 32087; Mature: 32087

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDTAMARLNEATIVIYAVSVLFYFIDFLQHNRKAGKMAFWLLSIVWTLQTVYLSYFMWQ
CCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TGRFPVLNITEALYFYAWVLVTLSLVVTQILRVDFIVFFTNVIGFSMIAIHTFSPTDQHS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHH
AAFSGQLVSELLVIHITMAILSYGAFSLSFVFSLLYQFQYSLLKKKKWGKWLLRIEDLSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDYMAYVLNVIGVPMLLLSLILGVIWAYVSLETLYWFDSKVLGSFIVLLLYSYYLYIRMI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KELQGKVAALWNSACFLVLMINYFLLGSLSQFHWFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2110138; 8969504; 9384377 [H]