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The map label for this gene is fabHB [H]

Identifier: 154685474

GI number: 154685474

Start: 1020043

End: 1021020

Strand: Reverse

Name: fabHB [H]

Synonym: RBAM_010400

Alternate gene names: 154685474

Gene position: 1021020-1020043 (Counterclockwise)

Preceding gene: 154685476

Following gene: 154685467

Centisome position: 26.06

GC content: 51.64

Gene sequence:

>978_bases
ATGTCAAAATCTAAAATTACAGCAATCGGTACATATGCTCCGGCACGCCGATTAACAAACGCGGATTTGGAGCGCATCGT
CGATACATCTGATGAATGGATCGTCCAGCGCACCGGTATGAAGGAAAGACGCATTGCCGGCGAACATGAATTCACATCGG
ATTTGTGTGTGGAAGCGGTGAAAAACCTTGCAGAACGATACAGCGGAACTCTTGATGATGTCGATATGATCCTTGTCGCC
ACAACGACGGCGGACTATGCGTTTCCAAGCACCGCGGCACGCGTGCAGGCTTACTTCGGCTGGCCGCACACGGGGGCGCT
TGATATTAACGCCACATGCGCCGGACTCACTTACGGCCTTCAGCTCGCAGACGCATTAATTACCGCCGGTTCCCATCAAA
AAGTGATTGTCATTGCCGGTGAAACATTATCAAAGGTAACGGATTATACTGACCGGACGACCTGCGTTCTTTTCGGAGAC
GCTGCTGGCGCCCTATTGGTAGAACGCGACGAATCAGCGCCGGGCTTTTTGGCAGCCGTGCAAGGAACAGCGGGAGGCAG
CGCGGACGTGCTGTATCGCACGGGACTGAGCGCAGAATTAAACGGCGAGCCGCTTAAAGGCGGAGGAAACATGGTGCAAA
ACGGGCGCGAAGTATATAAATGGGCGGCCAGAACCGTGCCTGAGGAATGCAATGCCCTTTTAGAAAAAGCCGGCTTTTCA
AAAGACGATCTGGATTGGTTCGTTCCTCACAGCGCCAACATGCGGATGATCGAATCCATCTGCGAAAAACTGCCCTTCCC
ACTTGAACGGACATTGACAAGCGTTGAATATTACGGCAACACTTCATCGGTTTCTATTATTCTCGCATTGGATGAAGCTG
TGAAAGCAAAAAAACTGTCGGAAGGCCAGACGCTGGTATTATTCGGGTTCGGCGGCGGATTGACGTATACCGGACTGTTG
GTAAGATGGGGATTTTAA

Upstream 100 bases:

>100_bases
TGCTCCCCAAACAGCGGATGCTGCTTGGGTTTTTTTATTAAAATTAGTACCAAGTAATAATATCAGGTGTTATAATCTGA
TATAAAGGAGTGATTTTTTC

Downstream 100 bases:

>100_bases
TAGTACGACGATCGAAATCTAAAAAAAGAGGCCCTGAGCATCTGCTCAGAGCCTCTTTTTCTTATGCTGTTATTTCTTCT
TCCGTTTTGTGTTCTTTTTT

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III protein 2; Beta-ketoacyl-ACP synthase III 2; KAS III 2; bFabH2 [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MSKSKITAIGTYAPARRLTNADLERIVDTSDEWIVQRTGMKERRIAGEHEFTSDLCVEAVKNLAERYSGTLDDVDMILVA
TTTADYAFPSTAARVQAYFGWPHTGALDINATCAGLTYGLQLADALITAGSHQKVIVIAGETLSKVTDYTDRTTCVLFGD
AAGALLVERDESAPGFLAAVQGTAGGSADVLYRTGLSAELNGEPLKGGGNMVQNGREVYKWAARTVPEECNALLEKAGFS
KDDLDWFVPHSANMRMIESICEKLPFPLERTLTSVEYYGNTSSVSIILALDEAVKAKKLSEGQTLVLFGFGGGLTYTGLL
VRWGF

Sequences:

>Translated_325_residues
MSKSKITAIGTYAPARRLTNADLERIVDTSDEWIVQRTGMKERRIAGEHEFTSDLCVEAVKNLAERYSGTLDDVDMILVA
TTTADYAFPSTAARVQAYFGWPHTGALDINATCAGLTYGLQLADALITAGSHQKVIVIAGETLSKVTDYTDRTTCVLFGD
AAGALLVERDESAPGFLAAVQGTAGGSADVLYRTGLSAELNGEPLKGGGNMVQNGREVYKWAARTVPEECNALLEKAGFS
KDDLDWFVPHSANMRMIESICEKLPFPLERTLTSVEYYGNTSSVSIILALDEAVKAKKLSEGQTLVLFGFGGGLTYTGLL
VRWGF
>Mature_324_residues
SKSKITAIGTYAPARRLTNADLERIVDTSDEWIVQRTGMKERRIAGEHEFTSDLCVEAVKNLAERYSGTLDDVDMILVAT
TTADYAFPSTAARVQAYFGWPHTGALDINATCAGLTYGLQLADALITAGSHQKVIVIAGETLSKVTDYTDRTTCVLFGDA
AGALLVERDESAPGFLAAVQGTAGGSADVLYRTGLSAELNGEPLKGGGNMVQNGREVYKWAARTVPEECNALLEKAGFSK
DDLDWFVPHSANMRMIESICEKLPFPLERTLTSVEYYGNTSSVSIILALDEAVKAKKLSEGQTLVLFGFGGGLTYTGLLV
RWGF

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=320, Percent_Identity=37.5, Blast_Score=218, Evalue=5e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 35030; Mature: 34899

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKSKITAIGTYAPARRLTNADLERIVDTSDEWIVQRTGMKERRIAGEHEFTSDLCVEAV
CCCCCEEEEECCCHHHHHCHHHHHHHHCCCCHHEEECCCCHHHHCCCCCCCHHHHHHHHH
KNLAERYSGTLDDVDMILVATTTADYAFPSTAARVQAYFGWPHTGALDINATCAGLTYGL
HHHHHHHCCCCCCCEEEEEEEECCCCCCCCHHHHEEEEECCCCCCEEEECCCHHHHHHHH
QLADALITAGSHQKVIVIAGETLSKVTDYTDRTTCVLFGDAAGALLVERDESAPGFLAAV
HHHHHHHCCCCCCEEEEEECCHHHHHHCCCCCEEEEEEECCCCEEEEEECCCCCCEEEEE
QGTAGGSADVLYRTGLSAELNGEPLKGGGNMVQNGREVYKWAARTVPEECNALLEKAGFS
ECCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHCCCHHHHHHHHHCCCC
KDDLDWFVPHSANMRMIESICEKLPFPLERTLTSVEYYGNTSSVSIILALDEAVKAKKLS
CCCCCEECCCCCCHHHHHHHHHHCCCCHHHHHHHHEECCCCCCEEEEEEECHHHHHHHCC
EGQTLVLFGFGGGLTYTGLLVRWGF
CCCEEEEEECCCCCEEEEEEEEECC
>Mature Secondary Structure 
SKSKITAIGTYAPARRLTNADLERIVDTSDEWIVQRTGMKERRIAGEHEFTSDLCVEAV
CCCCEEEEECCCHHHHHCHHHHHHHHCCCCHHEEECCCCHHHHCCCCCCCHHHHHHHHH
KNLAERYSGTLDDVDMILVATTTADYAFPSTAARVQAYFGWPHTGALDINATCAGLTYGL
HHHHHHHCCCCCCCEEEEEEEECCCCCCCCHHHHEEEEECCCCCCEEEECCCHHHHHHHH
QLADALITAGSHQKVIVIAGETLSKVTDYTDRTTCVLFGDAAGALLVERDESAPGFLAAV
HHHHHHHCCCCCCEEEEEECCHHHHHHCCCCCEEEEEEECCCCEEEEEECCCCCCEEEEE
QGTAGGSADVLYRTGLSAELNGEPLKGGGNMVQNGREVYKWAARTVPEECNALLEKAGFS
ECCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHCCCHHHHHHHHHCCCC
KDDLDWFVPHSANMRMIESICEKLPFPLERTLTSVEYYGNTSSVSIILALDEAVKAKKLS
CCCCCEECCCCCCHHHHHHHHHHCCCCHHHHHHHHEECCCCCCEEEEEEECHHHHHHHCC
EGQTLVLFGFGGGLTYTGLLVRWGF
CCCEEEEEECCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 10629181; 12737802 [H]