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The map label for this gene is lmrA [H]

Identifier: 154684768

GI number: 154684768

Start: 269807

End: 270373

Strand: Reverse

Name: lmrA [H]

Synonym: RBAM_002990

Alternate gene names: 154684768

Gene position: 270373-269807 (Counterclockwise)

Preceding gene: 154684773

Following gene: 154684767

Centisome position: 6.9

GC content: 46.21

Gene sequence:

>567_bases
ATGAGCTATGGAGATTCTCGTGAAAAAATCCTCGCCGCGGCAACCAGGCTGTTTCAGCTTCAGGGGTATTACGGCACGGG
GCTGAATCAGATTATTAAAGAAAGCGGTGCGCCGAAAGGTTCTCTTTACTATCATTTTCCGGACGGCAAAGAGCAGCTCG
CCATTGAGGCTGTCAATGAAATGAGCCATTATATCCGTATGAAAATAAAAGAAAGCCTTGATGCCCATCCTGATCCTGCG
GAAAGCATTCAAGCGTTTTTACAGGACTTATCAAGCCAATTCACATGTCCGGAGAACTTTGAAGGGTTTCCTGTCGGTTT
ACTGGCTGCCGAGACTGCTTTAAAGAGCGAAAAGCTCCAGCAGGCCTGTCAAAGCGCTTATCAGGAATGGGAGAATCTGT
TCGCGGGCAAATTGAGATCAGCCGGTTTTTCTGATGAGAAAGCGGCGGAAATCAGCACTGTTTTAAATGCCTTGATAGAA
GGCGGCATCATTGTGTCCTTAGCCAAAAAAGACAAAATGCCGATCCTCCATATTTCTAAACAAATCCCGAACCTGCTGAA
GACATAA

Upstream 100 bases:

>100_bases
AAATAACCGTTAAAAAACCTTGACACCATCATGTGAAATCAAGATAATAGACCAGTCACTATATTTTAAATTTGTCAAAA
ATCAGTAAGGTGGGAACATT

Downstream 100 bases:

>100_bases
AATACGAGAGACATGTACGTATAGAAAGAGAGGAGAATGATTTTGGAAAACGCTCAGCCTTCCAAACAATATAAAGTCAT
GCCGATCATGATTTCTTTAC

Product: LmrA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MSYGDSREKILAAATRLFQLQGYYGTGLNQIIKESGAPKGSLYYHFPDGKEQLAIEAVNEMSHYIRMKIKESLDAHPDPA
ESIQAFLQDLSSQFTCPENFEGFPVGLLAAETALKSEKLQQACQSAYQEWENLFAGKLRSAGFSDEKAAEISTVLNALIE
GGIIVSLAKKDKMPILHISKQIPNLLKT

Sequences:

>Translated_188_residues
MSYGDSREKILAAATRLFQLQGYYGTGLNQIIKESGAPKGSLYYHFPDGKEQLAIEAVNEMSHYIRMKIKESLDAHPDPA
ESIQAFLQDLSSQFTCPENFEGFPVGLLAAETALKSEKLQQACQSAYQEWENLFAGKLRSAGFSDEKAAEISTVLNALIE
GGIIVSLAKKDKMPILHISKQIPNLLKT
>Mature_187_residues
SYGDSREKILAAATRLFQLQGYYGTGLNQIIKESGAPKGSLYYHFPDGKEQLAIEAVNEMSHYIRMKIKESLDAHPDPAE
SIQAFLQDLSSQFTCPENFEGFPVGLLAAETALKSEKLQQACQSAYQEWENLFAGKLRSAGFSDEKAAEISTVLNALIEG
GIIVSLAKKDKMPILHISKQIPNLLKT

Specific function: Acts as repressor of the lincomycin-resistance (lmrAB) and yxaGH operons [H]

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 20742; Mature: 20611

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYGDSREKILAAATRLFQLQGYYGTGLNQIIKESGAPKGSLYYHFPDGKEQLAIEAVNE
CCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHH
MSHYIRMKIKESLDAHPDPAESIQAFLQDLSSQFTCPENFEGFPVGLLAAETALKSEKLQ
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
QACQSAYQEWENLFAGKLRSAGFSDEKAAEISTVLNALIEGGIIVSLAKKDKMPILHISK
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHH
QIPNLLKT
HHHHHHCC
>Mature Secondary Structure 
SYGDSREKILAAATRLFQLQGYYGTGLNQIIKESGAPKGSLYYHFPDGKEQLAIEAVNE
CCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHH
MSHYIRMKIKESLDAHPDPAESIQAFLQDLSSQFTCPENFEGFPVGLLAAETALKSEKLQ
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
QACQSAYQEWENLFAGKLRSAGFSDEKAAEISTVLNALIEGGIIVSLAKKDKMPILHISK
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHH
QIPNLLKT
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377 [H]