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The map label for this gene is ctaD [H]

Identifier: 154248566

GI number: 154248566

Start: 5135141

End: 5136763

Strand: Reverse

Name: ctaD [H]

Synonym: Xaut_4647

Alternate gene names: 154248566

Gene position: 5136763-5135141 (Counterclockwise)

Preceding gene: 154248567

Following gene: 154248565

Centisome position: 96.76

GC content: 64.51

Gene sequence:

>1623_bases
ATGGCCACCGAGGCAGTCACCCACACCCACGACGACCACGCCGACCACGACGCGCACATCCCCACCGGCTGGAAGCGCTG
GGTCTTCTCGACCAATCACAAGGACATCGGGATCATGTACCTGATCTTCGCCATCGTGGCGGGGATCGTGGGCGGCATCC
TGTCCATCGCCATCCGGATGGAGCTGCAGCATCCGGGCCTGCAGATCTTCTCCAATCCGCAGACCTTCAACGTCTTCACC
ACGGGCCACGGCCTCATCATGATCTTCTTCATGGTGATGCCCGCCCTCATCGGCGGCTACGGCAACTATTTCGCCCCGCT
GATGATCGGCGCGCCGGACACGGCCTTCCCGCGGATCAACAACATCGCCTTCTGGCTGCTGCCGCCGTCCTTCATCCTGG
CGCTGTCGTCGCTGTTCGTGGAAGGCGCGGCCGGCTCCAACGGCTTCGGCGGCGGCTGGACCATCTATCCCCCGCTGTCG
TCCAAGCTCGGCCATCCCGGCCCGGCCATGGACCTTCTGATCTTCTCGCTGCACATCGCCGGTGCCTCGTCGCTGCTGGG
CGCCATCAACCTCATCACCACCATCTTCAACATGCGCGCGCCGGGCATGACGCTGCACAAGATGCCGCTGTTCGCCTGGT
CCCAGCTCATCACCGGCTTCCTGCTGCTGCTGTCGCTGCCGGTGCTGGCGGGCGCCATCACCATGCTGCTCACCGACCGC
AACTTCGGCACGACCTTCTTCGACCCCGCGGGCGGTGGTGACCCGATCCTGTTCCAGCATCTGTTCTGGTTCTTCGGTCA
CCCCGAGGTGTACATCCTGATCCTGCCCGGGTTCGGCATCGTCTCCCACATCATCTCCACCTTCTCGCGCAAGCCCATCT
TCGGCTATCTCGGCATGGCCTACGCCATGGTCGCCATCGGCGTGGTGGGCTTCGTGGTGTGGGCGCACCACATGTACACG
GTGGGCCTGTCCAGCGGCACGCAGTCCTACTTCGTGGCCGCCACCATGATCATCGCGGTACCCACGGGCGTGAAGATCTT
CTCCTGGATCGCCACCATGTGGGGCGGCTCGCTGCAGTTCCGCACCCCCATGCTGTGGGCCATCGGCTTCATCTTCCTGT
TCACCGTGGGCGGCGTGACGGGCGTGGTGCTCTCCAACGCCGGCATCGACCGCTCACTGCACGACACCTATTACGTGGTG
GCCCACTTCCACTACGTGCTGTCGCTCGGCGCCGTGTTCGCCATCTTCGCCGGCTGGTACTACTGGTTCCCCAAGATGAG
CGGCTACATGATCCCGGAATTCTGGGGCAAGCTGCACTTCTGGGTCACCTTCGTGGGTGTGAACCTGGTGTTCTTCCCGC
AGCACTTCCTCGGGCTCGCCGGCATGCCGCGCCGCTACGCGGACTATCCGGACGCGTTCGCGGGCTGGAACTTCGTCTCC
TCCATCGGCTCCTATATCTCGGGCGTGGCGGTGCTGATCTTCCTCACCGGCACGGCGCTCGCCTTCATCCGCAAGGAAAA
GGCCGGCGACAATCCGTGGGGTCCCGGCGCCAGCACGCTGGAGTGGACCCTGTCCTCGCCGCCGCCCTTCCACCAGTTCG
AAGTGCTGCCGCGCATCAAGTGA

Upstream 100 bases:

>100_bases
CCTCTTTGAAATTGCGTCACCGGTCGCGGCCGGGGGCGGGAGCAGGCAAGCGACGGTGCGGCGGAACGGGCGCCAGTGCC
GGCAGACAAGGATAGCGGGA

Downstream 100 bases:

>100_bases
TGCCTTGGCCGCGCGCGGCCGTGACCTTCAAGAAGCCGCGGGCGACCGCGGCTTCTGCCACCTTCGGGATCCAAGGCGCA
GCATCTGGCGCGTCTTGCCG

Product: cytochrome c oxidase subunit I type

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 540; Mature: 539

Protein sequence:

>540_residues
MATEAVTHTHDDHADHDAHIPTGWKRWVFSTNHKDIGIMYLIFAIVAGIVGGILSIAIRMELQHPGLQIFSNPQTFNVFT
TGHGLIMIFFMVMPALIGGYGNYFAPLMIGAPDTAFPRINNIAFWLLPPSFILALSSLFVEGAAGSNGFGGGWTIYPPLS
SKLGHPGPAMDLLIFSLHIAGASSLLGAINLITTIFNMRAPGMTLHKMPLFAWSQLITGFLLLLSLPVLAGAITMLLTDR
NFGTTFFDPAGGGDPILFQHLFWFFGHPEVYILILPGFGIVSHIISTFSRKPIFGYLGMAYAMVAIGVVGFVVWAHHMYT
VGLSSGTQSYFVAATMIIAVPTGVKIFSWIATMWGGSLQFRTPMLWAIGFIFLFTVGGVTGVVLSNAGIDRSLHDTYYVV
AHFHYVLSLGAVFAIFAGWYYWFPKMSGYMIPEFWGKLHFWVTFVGVNLVFFPQHFLGLAGMPRRYADYPDAFAGWNFVS
SIGSYISGVAVLIFLTGTALAFIRKEKAGDNPWGPGASTLEWTLSSPPPFHQFEVLPRIK

Sequences:

>Translated_540_residues
MATEAVTHTHDDHADHDAHIPTGWKRWVFSTNHKDIGIMYLIFAIVAGIVGGILSIAIRMELQHPGLQIFSNPQTFNVFT
TGHGLIMIFFMVMPALIGGYGNYFAPLMIGAPDTAFPRINNIAFWLLPPSFILALSSLFVEGAAGSNGFGGGWTIYPPLS
SKLGHPGPAMDLLIFSLHIAGASSLLGAINLITTIFNMRAPGMTLHKMPLFAWSQLITGFLLLLSLPVLAGAITMLLTDR
NFGTTFFDPAGGGDPILFQHLFWFFGHPEVYILILPGFGIVSHIISTFSRKPIFGYLGMAYAMVAIGVVGFVVWAHHMYT
VGLSSGTQSYFVAATMIIAVPTGVKIFSWIATMWGGSLQFRTPMLWAIGFIFLFTVGGVTGVVLSNAGIDRSLHDTYYVV
AHFHYVLSLGAVFAIFAGWYYWFPKMSGYMIPEFWGKLHFWVTFVGVNLVFFPQHFLGLAGMPRRYADYPDAFAGWNFVS
SIGSYISGVAVLIFLTGTALAFIRKEKAGDNPWGPGASTLEWTLSSPPPFHQFEVLPRIK
>Mature_539_residues
ATEAVTHTHDDHADHDAHIPTGWKRWVFSTNHKDIGIMYLIFAIVAGIVGGILSIAIRMELQHPGLQIFSNPQTFNVFTT
GHGLIMIFFMVMPALIGGYGNYFAPLMIGAPDTAFPRINNIAFWLLPPSFILALSSLFVEGAAGSNGFGGGWTIYPPLSS
KLGHPGPAMDLLIFSLHIAGASSLLGAINLITTIFNMRAPGMTLHKMPLFAWSQLITGFLLLLSLPVLAGAITMLLTDRN
FGTTFFDPAGGGDPILFQHLFWFFGHPEVYILILPGFGIVSHIISTFSRKPIFGYLGMAYAMVAIGVVGFVVWAHHMYTV
GLSSGTQSYFVAATMIIAVPTGVKIFSWIATMWGGSLQFRTPMLWAIGFIFLFTVGGVTGVVLSNAGIDRSLHDTYYVVA
HFHYVLSLGAVFAIFAGWYYWFPKMSGYMIPEFWGKLHFWVTFVGVNLVFFPQHFLGLAGMPRRYADYPDAFAGWNFVSS
IGSYISGVAVLIFLTGTALAFIRKEKAGDNPWGPGASTLEWTLSSPPPFHQFEVLPRIK

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=513, Percent_Identity=61.4035087719298, Blast_Score=598, Evalue=1e-171,
Organism=Escherichia coli, GI1786634, Length=522, Percent_Identity=42.72030651341, Blast_Score=397, Evalue=1e-112,
Organism=Saccharomyces cerevisiae, GI6226519, Length=531, Percent_Identity=57.0621468926554, Blast_Score=603, Evalue=1e-173,
Organism=Saccharomyces cerevisiae, GI6226524, Length=327, Percent_Identity=62.3853211009174, Blast_Score=417, Evalue=1e-117,
Organism=Saccharomyces cerevisiae, GI6226523, Length=252, Percent_Identity=57.1428571428571, Blast_Score=270, Evalue=4e-73,
Organism=Saccharomyces cerevisiae, GI6226522, Length=79, Percent_Identity=45.5696202531646, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6226521, Length=66, Percent_Identity=46.969696969697, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 59221; Mature: 59090

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATEAVTHTHDDHADHDAHIPTGWKRWVFSTNHKDIGIMYLIFAIVAGIVGGILSIAIRM
CCCCCCCCCCCCCCCCCCCCCCCHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHE
ELQHPGLQIFSNPQTFNVFTTGHGLIMIFFMVMPALIGGYGNYFAPLMIGAPDTAFPRIN
EECCCCCEEECCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCHHCCEEECCCCCCCCCCC
NIAFWLLPPSFILALSSLFVEGAAGSNGFGGGWTIYPPLSSKLGHPGPAMDLLIFSLHIA
CEEEEEECHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCHHCCCCCCCHHHHHHHHHHHH
GASSLLGAINLITTIFNMRAPGMTLHKMPLFAWSQLITGFLLLLSLPVLAGAITMLLTDR
CHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
NFGTTFFDPAGGGDPILFQHLFWFFGHPEVYILILPGFGIVSHIISTFSRKPIFGYLGMA
CCCCCEECCCCCCCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCHHHHHHHH
YAMVAIGVVGFVVWAHHMYTVGLSSGTQSYFVAATMIIAVPTGVKIFSWIATMWGGSLQF
HHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEE
RTPMLWAIGFIFLFTVGGVTGVVLSNAGIDRSLHDTYYVVAHFHYVLSLGAVFAIFAGWY
CCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YWFPKMSGYMIPEFWGKLHFWVTFVGVNLVFFPQHFLGLAGMPRRYADYPDAFAGWNFVS
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHEEECHHHHCCCCCCCHHCCCCCHHHHHHHHH
SIGSYISGVAVLIFLTGTALAFIRKEKAGDNPWGPGASTLEWTLSSPPPFHQFEVLPRIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCHHCCCCCCC
>Mature Secondary Structure 
ATEAVTHTHDDHADHDAHIPTGWKRWVFSTNHKDIGIMYLIFAIVAGIVGGILSIAIRM
CCCCCCCCCCCCCCCCCCCCCCHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHE
ELQHPGLQIFSNPQTFNVFTTGHGLIMIFFMVMPALIGGYGNYFAPLMIGAPDTAFPRIN
EECCCCCEEECCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCHHCCEEECCCCCCCCCCC
NIAFWLLPPSFILALSSLFVEGAAGSNGFGGGWTIYPPLSSKLGHPGPAMDLLIFSLHIA
CEEEEEECHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCHHCCCCCCCHHHHHHHHHHHH
GASSLLGAINLITTIFNMRAPGMTLHKMPLFAWSQLITGFLLLLSLPVLAGAITMLLTDR
CHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
NFGTTFFDPAGGGDPILFQHLFWFFGHPEVYILILPGFGIVSHIISTFSRKPIFGYLGMA
CCCCCEECCCCCCCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCHHHHHHHH
YAMVAIGVVGFVVWAHHMYTVGLSSGTQSYFVAATMIIAVPTGVKIFSWIATMWGGSLQF
HHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEE
RTPMLWAIGFIFLFTVGGVTGVVLSNAGIDRSLHDTYYVVAHFHYVLSLGAVFAIFAGWY
CCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YWFPKMSGYMIPEFWGKLHFWVTFVGVNLVFFPQHFLGLAGMPRRYADYPDAFAGWNFVS
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHEEECHHHHCCCCCCCHHCCCCCHHHHHHHHH
SIGSYISGVAVLIFLTGTALAFIRKEKAGDNPWGPGASTLEWTLSSPPPFHQFEVLPRIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2172930; 1965217; 12597275 [H]