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The map label for this gene is ctaC [H]

Identifier: 154248567

GI number: 154248567

Start: 5136891

End: 5137751

Strand: Reverse

Name: ctaC [H]

Synonym: Xaut_4648

Alternate gene names: 154248567

Gene position: 5137751-5136891 (Counterclockwise)

Preceding gene: 154248571

Following gene: 154248566

Centisome position: 96.78

GC content: 64.92

Gene sequence:

>861_bases
ATGAAGTCGTTCCTCCGCTCCGCTGCCCTTGCCATGGGCACGTGCGCCGCGAGCCTGTTCGCGAGCGCCGCCTTTGCCGA
GACCGGCCAGCCCTCGCCGTGGCAGATCAATCTCCAGGGTGCCGCTACGCCGGTGATGGAGCAGATCCACAGCTTCAACA
CGATGATGCTCATCATCATCACCTCCATCGTGCTGTTCGTGCTGGTGCTGCTCGCCATCGTGGTGGTGCGCTTCAACGAG
CGCGCCAATCCGGTGCCGTCCAAGACCAGCCACAACACCCTCATCGAGGTGGCCTGGACCGTGATCCCGGTGATGATCCT
CGTGCTCATCGCCATCCCGTCCTTCCGCCTGCTCCATCTTGAGCTGAACATTCCCAAGCCGGACATGACGGTGAAGGTGA
CGGGGCACCAGTGGTACTGGTCCTACGACTATCCCGACAACGGCGGCTTCTCCTTCGATTCCTACCTGGTGGCCGAGAAG
GACCTGAAGCCGGGCCAGCCGCGCCTGCTGGCGGTGGACAATGAGGTGGTGGTGCCGGTCAACAAGATCGTGCGCATCCA
GGTCACCTCGTCCGACGTGATCCACTCGTTCGCGATGCCCGCGTTCGGCGTGAAGATCGACGCCAATCCCGGCCGCCTGA
ACGAGAGCTGGTTCAAGGTGACCCGTGAGGGCATCTATTACGGCCAGTGCTCCGAGCTGTGCGGCCGTGACCATGCCTTC
ATGCCGATCGCGATTCGCGCGGTGAGCGAGGCGGACTTCGCGGCGTGGGCTGCCCAGGCCAAGGCGAAGTTCGCATCCGC
GGCCGATGCCGCCGGCAAGCTGGCTGACGCCGGCGAGCCCGCCGGCGCTCTGGCGCGCTGA

Upstream 100 bases:

>100_bases
TCACTTGAACAAGTGGTCCGGACGGCGCGCCGCTGAGCGTGCAGGGCGGGCGCAGCACGTACGGTGGTTCAATCCGCCGG
GCCAGGGAGAGCCGTTGAAG

Downstream 100 bases:

>100_bases
GACTTCGGCCGGCGCATGGCGCCGGCGCCTCTTTGAAATTGCGTCACCGGTCGCGGCCGGGGGCGGGAGCAGGCAAGCGA
CGGTGCGGCGGAACGGGCGC

Product: cytochrome c oxidase subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MKSFLRSAALAMGTCAASLFASAAFAETGQPSPWQINLQGAATPVMEQIHSFNTMMLIIITSIVLFVLVLLAIVVVRFNE
RANPVPSKTSHNTLIEVAWTVIPVMILVLIAIPSFRLLHLELNIPKPDMTVKVTGHQWYWSYDYPDNGGFSFDSYLVAEK
DLKPGQPRLLAVDNEVVVPVNKIVRIQVTSSDVIHSFAMPAFGVKIDANPGRLNESWFKVTREGIYYGQCSELCGRDHAF
MPIAIRAVSEADFAAWAAQAKAKFASAADAAGKLADAGEPAGALAR

Sequences:

>Translated_286_residues
MKSFLRSAALAMGTCAASLFASAAFAETGQPSPWQINLQGAATPVMEQIHSFNTMMLIIITSIVLFVLVLLAIVVVRFNE
RANPVPSKTSHNTLIEVAWTVIPVMILVLIAIPSFRLLHLELNIPKPDMTVKVTGHQWYWSYDYPDNGGFSFDSYLVAEK
DLKPGQPRLLAVDNEVVVPVNKIVRIQVTSSDVIHSFAMPAFGVKIDANPGRLNESWFKVTREGIYYGQCSELCGRDHAF
MPIAIRAVSEADFAAWAAQAKAKFASAADAAGKLADAGEPAGALAR
>Mature_286_residues
MKSFLRSAALAMGTCAASLFASAAFAETGQPSPWQINLQGAATPVMEQIHSFNTMMLIIITSIVLFVLVLLAIVVVRFNE
RANPVPSKTSHNTLIEVAWTVIPVMILVLIAIPSFRLLHLELNIPKPDMTVKVTGHQWYWSYDYPDNGGFSFDSYLVAEK
DLKPGQPRLLAVDNEVVVPVNKIVRIQVTSSDVIHSFAMPAFGVKIDANPGRLNESWFKVTREGIYYGQCSELCGRDHAF
MPIAIRAVSEADFAAWAAQAKAKFASAADAAGKLADAGEPAGALAR

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=214, Percent_Identity=43.4579439252336, Blast_Score=205, Evalue=5e-53,
Organism=Escherichia coli, GI1786635, Length=238, Percent_Identity=27.7310924369748, Blast_Score=70, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6226540, Length=240, Percent_Identity=42.0833333333333, Blast_Score=194, Evalue=1e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 31091; Mature: 31091

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSFLRSAALAMGTCAASLFASAAFAETGQPSPWQINLQGAATPVMEQIHSFNTMMLIII
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHCCHHHHHHH
TSIVLFVLVLLAIVVVRFNERANPVPSKTSHNTLIEVAWTVIPVMILVLIAIPSFRLLHL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEE
ELNIPKPDMTVKVTGHQWYWSYDYPDNGGFSFDSYLVAEKDLKPGQPRLLAVDNEVVVPV
EEECCCCCEEEEEECCEEEEEECCCCCCCCCCHHEEEEECCCCCCCCEEEEECCCEEEEC
NKIVRIQVTSSDVIHSFAMPAFGVKIDANPGRLNESWFKVTREGIYYGQCSELCGRDHAF
CEEEEEEECCHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHCCEEECCHHHHHCCCCCE
MPIAIRAVSEADFAAWAAQAKAKFASAADAAGKLADAGEPAGALAR
EEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKSFLRSAALAMGTCAASLFASAAFAETGQPSPWQINLQGAATPVMEQIHSFNTMMLIII
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHCCHHHHHHH
TSIVLFVLVLLAIVVVRFNERANPVPSKTSHNTLIEVAWTVIPVMILVLIAIPSFRLLHL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEE
ELNIPKPDMTVKVTGHQWYWSYDYPDNGGFSFDSYLVAEKDLKPGQPRLLAVDNEVVVPV
EEECCCCCEEEEEECCEEEEEECCCCCCCCCCHHEEEEECCCCCCCCEEEEECCCEEEEC
NKIVRIQVTSSDVIHSFAMPAFGVKIDANPGRLNESWFKVTREGIYYGQCSELCGRDHAF
CEEEEEEECCHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHCCEEECCHHHHHCCCCCE
MPIAIRAVSEADFAAWAAQAKAKFASAADAAGKLADAGEPAGALAR
EEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA