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The map label for this gene is fabZ

Identifier: 154248349

GI number: 154248349

Start: 4913686

End: 4914171

Strand: Reverse

Name: fabZ

Synonym: Xaut_4429

Alternate gene names: 154248349

Gene position: 4914171-4913686 (Counterclockwise)

Preceding gene: 154248350

Following gene: 154248348

Centisome position: 92.56

GC content: 62.96

Gene sequence:

>486_bases
ATGAACGATACGACGCATGCCGCCGAAGGTGCGGAGCCGAAGGTGCTCGCCAGCGCTGACATCCTGAAGGTGCTCACCTG
TCTGCCCCACCGCTATCCGTTCCTCATGGTGGACCGCGTGGAGCAGATCGACGGCGACCTTTCCTGCGTCGGCATCAAGA
ATGTGACCGCTAACGAGCCGCACTTCCAGGGCCATTTCCCCGGCAACCCGGTGATGCCGGGAGTGCTCATCATCGAGGGC
ATGGCGCAGACCGCCGGTGTCGTCTGTGTGCTCGGCAAGGACAAGGAAAAGCCGTCCCTGGTCTATTTCATGACCATCGA
CGAGGCGAAGTTCCGCCGTCCGGTCGTGCCAGGCGACGTGCTTGAATATCACATGACGCGCATCTCCCGCCGCCGCAACA
TGTGGTGGTACCGCGGCGAGGCCAAGGTGCGCGGCGAGATCGTCGCGCAGGCCAAGGTGGGCGCCATGATCATGGAGAAC
AGCTAG

Upstream 100 bases:

>100_bases
CGGTGCGCGAATGGTTCCGCGAGGTAACGACCCTCAAGCGCCTCGCCGCGGCCAGCGCCCGGCGCGGCGGCAATGACGGG
GAAGGGGAAGGATCGGGGGA

Downstream 100 bases:

>100_bases
TGGCGAAGATCGACCCCACCGCTCGGGTGGAGAACCCGGCGGGGCTCGCGGATGACGTGGAGATCGGCCCCTATACAGTT
CTCGGTCCTGATGTGGTGCT

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MNDTTHAAEGAEPKVLASADILKVLTCLPHRYPFLMVDRVEQIDGDLSCVGIKNVTANEPHFQGHFPGNPVMPGVLIIEG
MAQTAGVVCVLGKDKEKPSLVYFMTIDEAKFRRPVVPGDVLEYHMTRISRRRNMWWYRGEAKVRGEIVAQAKVGAMIMEN
S

Sequences:

>Translated_161_residues
MNDTTHAAEGAEPKVLASADILKVLTCLPHRYPFLMVDRVEQIDGDLSCVGIKNVTANEPHFQGHFPGNPVMPGVLIIEG
MAQTAGVVCVLGKDKEKPSLVYFMTIDEAKFRRPVVPGDVLEYHMTRISRRRNMWWYRGEAKVRGEIVAQAKVGAMIMEN
S
>Mature_161_residues
MNDTTHAAEGAEPKVLASADILKVLTCLPHRYPFLMVDRVEQIDGDLSCVGIKNVTANEPHFQGHFPGNPVMPGVLIIEG
MAQTAGVVCVLGKDKEKPSLVYFMTIDEAKFRRPVVPGDVLEYHMTRISRRRNMWWYRGEAKVRGEIVAQAKVGAMIMEN
S

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=135, Percent_Identity=46.6666666666667, Blast_Score=129, Evalue=8e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 17923; Mature: 17923

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDTTHAAEGAEPKVLASADILKVLTCLPHRYPFLMVDRVEQIDGDLSCVGIKNVTANEP
CCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCEEEEEHHHHCCCCEEEEEECCCCCCCC
HFQGHFPGNPVMPGVLIIEGMAQTAGVVCVLGKDKEKPSLVYFMTIDEAKFRRPVVPGDV
CCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCCCCCCEEEEEEECCHHHCCCCCCHHH
LEYHMTRISRRRNMWWYRGEAKVRGEIVAQAKVGAMIMENS
HHHHHHHHHHHCCCEEECCCCEECEEEEEEEEECEEEEECC
>Mature Secondary Structure
MNDTTHAAEGAEPKVLASADILKVLTCLPHRYPFLMVDRVEQIDGDLSCVGIKNVTANEP
CCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCEEEEEHHHHCCCCEEEEEECCCCCCCC
HFQGHFPGNPVMPGVLIIEGMAQTAGVVCVLGKDKEKPSLVYFMTIDEAKFRRPVVPGDV
CCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCCCCCCEEEEEEECCHHHCCCCCCHHH
LEYHMTRISRRRNMWWYRGEAKVRGEIVAQAKVGAMIMENS
HHHHHHHHHHHCCCEEECCCCEECEEEEEEEEECEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA