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The map label for this gene is lpxA [H]

Identifier: 154248348

GI number: 154248348

Start: 4912880

End: 4913686

Strand: Reverse

Name: lpxA [H]

Synonym: Xaut_4428

Alternate gene names: 154248348

Gene position: 4913686-4912880 (Counterclockwise)

Preceding gene: 154248349

Following gene: 154248347

Centisome position: 92.56

GC content: 66.05

Gene sequence:

>807_bases
GTGGCGAAGATCGACCCCACCGCTCGGGTGGAGAACCCGGCGGGGCTCGCGGATGACGTGGAGATCGGCCCCTATACAGT
TCTCGGTCCTGATGTGGTGCTCAAGGAAGGGGTCAAGCTCCTCGCCCATGTGAACATCCAGGGCGTCACCACCATCGGCG
CGCGCACCACGGTCTTTCCGTTCGCCTCCCTCGGTACCGCACCCCAGTCGGTGCACTACAAGGGCGAGCGAACCGAGCTT
TTCATCGGCTCCGACTGCATCATCCGCGAGCATGCGACGGCCAGCATCGGCACGACAGGCGGCGGCGGGGTCACCCGCAT
CGGCAACGGCGTCATGATGATGACCGGGTCCCATGTGGGCCACGACTGCACCGTGGGCGACAGCGTGATCTTCGCCAACA
ATGCGGTGCTGGGCGGCCATGTGAGCGTCGGCGAGTTCACCTTCCTGGGTGGGCAGTGCGCGGTGCACCAGTTCACTCGC
ATCGGCGCCCAATGCATGATTTCCGGCCTCACCGGCGTGCGCGAGGATGTCATCCCCTTCGGCAATGTGCTGGGTCAGGC
CGGCAAGCTGGTCGGCCTCAACGTCGTCGGCATGAAGCGGCGCGGTTTCTCCAAATCCGACCTGCATGCGGCGCGGGCGG
TTTATCGCGATCTGTTCTTCGGCGAGGGCACGTTCGAGGCCCGGCTCGAAACCGTGCGCGAGCAGGCGGAGACTTCCGCC
TTCGCCGCGGCCGTGGTGAGCTTCATCGACGCGGACCGCAAGCGGCCGATCTGCCAGCCGTCGCGAGGCGTCATCAAGGA
GGAGTGA

Upstream 100 bases:

>100_bases
CCCGCCGCCGCAACATGTGGTGGTACCGCGGCGAGGCCAAGGTGCGCGGCGAGATCGTCGCGCAGGCCAAGGTGGGCGCC
ATGATCATGGAGAACAGCTA

Downstream 100 bases:

>100_bases
GGCGTGAGCCTTCCAGGGCAGAACGGGCAGGGTCCGGCGCCCGGCCCGGACACCCTGAAGGCGGCCGGCAGGGGTCCCGT
GGGCATCGTTGCCGGCGGCG

Product: acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine acyltransferase [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MAKIDPTARVENPAGLADDVEIGPYTVLGPDVVLKEGVKLLAHVNIQGVTTIGARTTVFPFASLGTAPQSVHYKGERTEL
FIGSDCIIREHATASIGTTGGGGVTRIGNGVMMMTGSHVGHDCTVGDSVIFANNAVLGGHVSVGEFTFLGGQCAVHQFTR
IGAQCMISGLTGVREDVIPFGNVLGQAGKLVGLNVVGMKRRGFSKSDLHAARAVYRDLFFGEGTFEARLETVREQAETSA
FAAAVVSFIDADRKRPICQPSRGVIKEE

Sequences:

>Translated_268_residues
MAKIDPTARVENPAGLADDVEIGPYTVLGPDVVLKEGVKLLAHVNIQGVTTIGARTTVFPFASLGTAPQSVHYKGERTEL
FIGSDCIIREHATASIGTTGGGGVTRIGNGVMMMTGSHVGHDCTVGDSVIFANNAVLGGHVSVGEFTFLGGQCAVHQFTR
IGAQCMISGLTGVREDVIPFGNVLGQAGKLVGLNVVGMKRRGFSKSDLHAARAVYRDLFFGEGTFEARLETVREQAETSA
FAAAVVSFIDADRKRPICQPSRGVIKEE
>Mature_267_residues
AKIDPTARVENPAGLADDVEIGPYTVLGPDVVLKEGVKLLAHVNIQGVTTIGARTTVFPFASLGTAPQSVHYKGERTELF
IGSDCIIREHATASIGTTGGGGVTRIGNGVMMMTGSHVGHDCTVGDSVIFANNAVLGGHVSVGEFTFLGGQCAVHQFTRI
GAQCMISGLTGVREDVIPFGNVLGQAGKLVGLNVVGMKRRGFSKSDLHAARAVYRDLFFGEGTFEARLETVREQAETSAF
AAAVVSFIDADRKRPICQPSRGVIKEE

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG1043

COG function: function code M; Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786378, Length=265, Percent_Identity=39.2452830188679, Blast_Score=187, Evalue=4e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010137
- InterPro:   IPR011004 [H]

Pfam domain/function: NA

EC number: =2.3.1.129 [H]

Molecular weight: Translated: 28217; Mature: 28085

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKIDPTARVENPAGLADDVEIGPYTVLGPDVVLKEGVKLLAHVNIQGVTTIGARTTVFP
CCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHCCEEEEEECCCEEEEECCCEEEEE
FASLGTAPQSVHYKGERTELFIGSDCIIREHATASIGTTGGGGVTRIGNGVMMMTGSHVG
HHHCCCCCCCEEECCCCEEEEECCCEEEECCCCCCCCCCCCCCEEECCCCEEEEECCCCC
HDCTVGDSVIFANNAVLGGHVSVGEFTFLGGQCAVHQFTRIGAQCMISGLTGVREDVIPF
CCCCCCCEEEEECCEEECCCEEECCEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
GNVLGQAGKLVGLNVVGMKRRGFSKSDLHAARAVYRDLFFGEGTFEARLETVREQAETSA
HHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
FAAAVVSFIDADRKRPICQPSRGVIKEE
HHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AKIDPTARVENPAGLADDVEIGPYTVLGPDVVLKEGVKLLAHVNIQGVTTIGARTTVFP
CCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHCCEEEEEECCCEEEEECCCEEEEE
FASLGTAPQSVHYKGERTELFIGSDCIIREHATASIGTTGGGGVTRIGNGVMMMTGSHVG
HHHCCCCCCCEEECCCCEEEEECCCEEEECCCCCCCCCCCCCCEEECCCCEEEEECCCCC
HDCTVGDSVIFANNAVLGGHVSVGEFTFLGGQCAVHQFTRIGAQCMISGLTGVREDVIPF
CCCCCCCEEEEECCEEECCCEEECCEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
GNVLGQAGKLVGLNVVGMKRRGFSKSDLHAARAVYRDLFFGEGTFEARLETVREQAETSA
HHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
FAAAVVSFIDADRKRPICQPSRGVIKEE
HHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA