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The map label for this gene is catA2 [H]

Identifier: 154248277

GI number: 154248277

Start: 4830443

End: 4831357

Strand: Reverse

Name: catA2 [H]

Synonym: Xaut_4357

Alternate gene names: 154248277

Gene position: 4831357-4830443 (Counterclockwise)

Preceding gene: 154248278

Following gene: 154248276

Centisome position: 91.0

GC content: 67.54

Gene sequence:

>915_bases
ATGGAAAAAGCCGCCATCGATGCCCTCTTGAAGGAGATGCAGGCGCCTACCCGCGGCGAGCCCACGCCCCGCGTGAAGGC
GATCGTGGACCGCATCGTCCGCGACCTGTTCTACGTCATCGACGAATATGACGTGGAGCCGAGCGAGTTCTGGAGCGCGG
TCAACTACCTGACGCAGGCCGGCCGCAACGACGAGTATGGCCTGATTGCCGCTGGCCTCGGCTTTGAGCGCTTTCTCGAC
GTGCGGCTCGACGCAGCGGAGGAAGCTGCCGGCCTTACCGGCGGCACCCCGCGCACCATCGAGGGGCCGCTCTATGTGGC
CGGCGCGCCCCTGTGCAAAGGCGAGGCGCGGCTCGACGACGGCTCGGAAGAGGGCGAGATCCTCATCATGCACGGGCAGG
TGCGCGACACCGACGGCCGCCCGGTAGCTGGCGCACATGTGGAGGTGTGGCACGCCAACACGCGGGGCAATTACTCCTTT
TTCGACAAGAGCCAGAGCCCCTTCAACCTGCGTCGGACCATCGAGACCGACGCCGATGGCCGCTACCGTTTCCGCACCAC
GATGCCATCGGGCTATGCGGTGCCCCCCGAAGGCTCCACCGACACGCTGCTGAAGCAGCTCGGCCGCCACGGGCACCGTC
CGGCGCACATCCATTTCTTCGTGAGCGCGCCGGGCTTTCGCAAGCTCACGACGCAGATCAACATCGACGGCGATCCCTAT
CTCCACGATGACTTCGCCTTCGCCACCCGCGATGGGCTGATCCCCGCCGTGGAGCGCAACCAGGACCCCGACGCCATCGC
CGAGGCCGGGCTGAATGCCCCGTTCGCGCGCATCGCCTTCGATTTCGAGCTGAGGTCGGAGGCCCTCGCCCTGCCCTCCG
CCGAGGTGCAGCGCCCGCGCGCGGAAGCCGCCTGA

Upstream 100 bases:

>100_bases
TCAGCCCCGTTCGCCAGTCCGTGGGGGCCTGAGACCCCCTGCCCTTTCGACCGATGCCCCAGCGCACGGCGCATAAAAAT
GCCCCATAAGGAGAACGCCC

Downstream 100 bases:

>100_bases
CCTCAAGGCATCATGCGCTTCAGACACCCGGCGCGGTCCGACCCGCGCCGGTTCGCCTGATCCCGACACAGCCCAGAACC
GCAAGATCAAGAACCCCTTG

Product: catechol 1,2-dioxygenase

Products: NA

Alternate protein names: 1,2-CTD 2; CDI2 [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MEKAAIDALLKEMQAPTRGEPTPRVKAIVDRIVRDLFYVIDEYDVEPSEFWSAVNYLTQAGRNDEYGLIAAGLGFERFLD
VRLDAAEEAAGLTGGTPRTIEGPLYVAGAPLCKGEARLDDGSEEGEILIMHGQVRDTDGRPVAGAHVEVWHANTRGNYSF
FDKSQSPFNLRRTIETDADGRYRFRTTMPSGYAVPPEGSTDTLLKQLGRHGHRPAHIHFFVSAPGFRKLTTQINIDGDPY
LHDDFAFATRDGLIPAVERNQDPDAIAEAGLNAPFARIAFDFELRSEALALPSAEVQRPRAEAA

Sequences:

>Translated_304_residues
MEKAAIDALLKEMQAPTRGEPTPRVKAIVDRIVRDLFYVIDEYDVEPSEFWSAVNYLTQAGRNDEYGLIAAGLGFERFLD
VRLDAAEEAAGLTGGTPRTIEGPLYVAGAPLCKGEARLDDGSEEGEILIMHGQVRDTDGRPVAGAHVEVWHANTRGNYSF
FDKSQSPFNLRRTIETDADGRYRFRTTMPSGYAVPPEGSTDTLLKQLGRHGHRPAHIHFFVSAPGFRKLTTQINIDGDPY
LHDDFAFATRDGLIPAVERNQDPDAIAEAGLNAPFARIAFDFELRSEALALPSAEVQRPRAEAA
>Mature_304_residues
MEKAAIDALLKEMQAPTRGEPTPRVKAIVDRIVRDLFYVIDEYDVEPSEFWSAVNYLTQAGRNDEYGLIAAGLGFERFLD
VRLDAAEEAAGLTGGTPRTIEGPLYVAGAPLCKGEARLDDGSEEGEILIMHGQVRDTDGRPVAGAHVEVWHANTRGNYSF
FDKSQSPFNLRRTIETDADGRYRFRTTMPSGYAVPPEGSTDTLLKQLGRHGHRPAHIHFFVSAPGFRKLTTQINIDGDPY
LHDDFAFATRDGLIPAVERNQDPDAIAEAGLNAPFARIAFDFELRSEALALPSAEVQRPRAEAA

Specific function: Can cleave 4-methyl-, 4-chloro-, and 3-methoxycatechol at lower rates than catechol, but has no activity with 4- nitrocatechol or protocatechuic acid [H]

COG id: COG3485

COG function: function code Q; Protocatechuate 3,4-dioxygenase beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the intradiol ring-cleavage dioxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007535
- InterPro:   IPR012801
- InterPro:   IPR000627
- InterPro:   IPR015889 [H]

Pfam domain/function: PF00775 Dioxygenase_C; PF04444 Dioxygenase_N [H]

EC number: =1.13.11.1 [H]

Molecular weight: Translated: 33499; Mature: 33499

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00083 INTRADIOL_DIOXYGENAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKAAIDALLKEMQAPTRGEPTPRVKAIVDRIVRDLFYVIDEYDVEPSEFWSAVNYLTQA
CCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
GRNDEYGLIAAGLGFERFLDVRLDAAEEAAGLTGGTPRTIEGPLYVAGAPLCKGEARLDD
CCCCCCEEEEECCCHHHHHHHHCCCHHHHCCCCCCCCCEECCCEEEECCCCCCCCCCCCC
GSEEGEILIMHGQVRDTDGRPVAGAHVEVWHANTRGNYSFFDKSQSPFNLRRTIETDADG
CCCCCCEEEEECCEECCCCCCCCCCEEEEEECCCCCCEEECCCCCCCCEEEEEECCCCCC
RYRFRTTMPSGYAVPPEGSTDTLLKQLGRHGHRPAHIHFFVSAPGFRKLTTQINIDGDPY
CEEEEEECCCCEECCCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCEEEEEEEECCCCCC
LHDDFAFATRDGLIPAVERNQDPDAIAEAGLNAPFARIAFDFELRSEALALPSAEVQRPR
CCCCCHHHHCCCCCCHHCCCCCHHHHHHCCCCCCHHHEEEEEECCCHHHCCCCHHHCCCC
AEAA
CCCC
>Mature Secondary Structure
MEKAAIDALLKEMQAPTRGEPTPRVKAIVDRIVRDLFYVIDEYDVEPSEFWSAVNYLTQA
CCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
GRNDEYGLIAAGLGFERFLDVRLDAAEEAAGLTGGTPRTIEGPLYVAGAPLCKGEARLDD
CCCCCCEEEEECCCHHHHHHHHCCCHHHHCCCCCCCCCEECCCEEEECCCCCCCCCCCCC
GSEEGEILIMHGQVRDTDGRPVAGAHVEVWHANTRGNYSFFDKSQSPFNLRRTIETDADG
CCCCCCEEEEECCEECCCCCCCCCCEEEEEECCCCCCEEECCCCCCCCEEEEEECCCCCC
RYRFRTTMPSGYAVPPEGSTDTLLKQLGRHGHRPAHIHFFVSAPGFRKLTTQINIDGDPY
CEEEEEECCCCEECCCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCEEEEEEEECCCCCC
LHDDFAFATRDGLIPAVERNQDPDAIAEAGLNAPFARIAFDFELRSEALALPSAEVQRPR
CCCCCHHHHCCCCCCHHCCCCCHHHHHHCCCCCCHHHEEEEEECCCHHHCCCCHHHCCCC
AEAA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9260969 [H]