Click here to switch to the map view.

The map label for this gene is nrdR

Identifier: 154248197

GI number: 154248197

Start: 4744277

End: 4744825

Strand: Direct

Name: nrdR

Synonym: Xaut_4277

Alternate gene names: 154248197

Gene position: 4744277-4744825 (Clockwise)

Preceding gene: 154248196

Following gene: 154248198

Centisome position: 89.36

GC content: 67.4

Gene sequence:

>549_bases
ATGCGCTGTCCCTATTGCGGCGGTCTCGACACGCAGGTGCGCGATTCCCGGCCGACGGAAGACAACACCGCCATCCGCCG
TCGCCGCATCTGCCCGGATTGCGGCGGCCGCTTCACCACCTTCGAGCGCGTGCAGCTGCGCGAGCTGATGGTGCTGAAGC
GCTCCGGCCGGCGGGTGCCGTTCGATCGCGACAAGCTCGCCCGCTCCGTGGACGTGGCCCTGCGCAAGCGTCCGGTGGAC
GGCGAGCGGGTGGAGCGCATGTTGTCCGGCATCGTCCGGCAGCTTGAAAGCATGGGCGATAGCGACATCACCTCGCAGAC
CATCGGCGAGATGGTGATGGAAGGCCTGAAGCAGCTCGACGACGTGGCCTATGTCCGCTTCGCCTCGGTCTACCGCAATT
TCCGCGAGGCCAAGGATTTCGAGAACGCGCTGGCCGAGCTCTCCCAGCCCGAACTGGCACAGTCCGATGACGTGAAAGCC
GAAGGCGGGGCTGAAGGCGGCCGGGACAAACCGAAGGCCGCCGGCAAGCCGCCCCGGAGCGCCGAATGA

Upstream 100 bases:

>100_bases
CCCTGAGGGCAAGTCCCCGGAGGGGCAAGTGCCAGCGCGTCTTGGTCTCGCGGACCGGTGTCCCCGTGCGAAGACGCCTG
AGCGCCGGAAAGGGTGAAGC

Downstream 100 bases:

>100_bases
GCGTGTCCCCCCTGTCCGCCCATCCCGTCACCTCGCCGGAGGACGACGAGCGGTTCATGGCCGAGGCCCTGAAGGTGGGC
CAGAGTGGGCTCGGGCGTAC

Product: ATP-cone domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MRCPYCGGLDTQVRDSRPTEDNTAIRRRRICPDCGGRFTTFERVQLRELMVLKRSGRRVPFDRDKLARSVDVALRKRPVD
GERVERMLSGIVRQLESMGDSDITSQTIGEMVMEGLKQLDDVAYVRFASVYRNFREAKDFENALAELSQPELAQSDDVKA
EGGAEGGRDKPKAAGKPPRSAE

Sequences:

>Translated_182_residues
MRCPYCGGLDTQVRDSRPTEDNTAIRRRRICPDCGGRFTTFERVQLRELMVLKRSGRRVPFDRDKLARSVDVALRKRPVD
GERVERMLSGIVRQLESMGDSDITSQTIGEMVMEGLKQLDDVAYVRFASVYRNFREAKDFENALAELSQPELAQSDDVKA
EGGAEGGRDKPKAAGKPPRSAE
>Mature_182_residues
MRCPYCGGLDTQVRDSRPTEDNTAIRRRRICPDCGGRFTTFERVQLRELMVLKRSGRRVPFDRDKLARSVDVALRKRPVD
GERVERMLSGIVRQLESMGDSDITSQTIGEMVMEGLKQLDDVAYVRFASVYRNFREAKDFENALAELSQPELAQSDDVKA
EGGAEGGRDKPKAAGKPPRSAE

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=147, Percent_Identity=45.578231292517, Blast_Score=129, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_XANP2 (A7INA4)

Other databases:

- EMBL:   CP000781
- RefSeq:   YP_001419155.1
- STRING:   A7INA4
- GeneID:   5423035
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_4277
- eggNOG:   COG1327
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- ProtClustDB:   CLSK2793701
- BioCyc:   XAUT78245:XAUT_4277-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 20481; Mature: 20481

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCPYCGGLDTQVRDSRPTEDNTAIRRRRICPDCGGRFTTFERVQLRELMVLKRSGRRVP
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
FDRDKLARSVDVALRKRPVDGERVERMLSGIVRQLESMGDSDITSQTIGEMVMEGLKQLD
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
DVAYVRFASVYRNFREAKDFENALAELSQPELAQSDDVKAEGGAEGGRDKPKAAGKPPRS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AE
CC
>Mature Secondary Structure
MRCPYCGGLDTQVRDSRPTEDNTAIRRRRICPDCGGRFTTFERVQLRELMVLKRSGRRVP
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
FDRDKLARSVDVALRKRPVDGERVERMLSGIVRQLESMGDSDITSQTIGEMVMEGLKQLD
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
DVAYVRFASVYRNFREAKDFENALAELSQPELAQSDDVKAEGGAEGGRDKPKAAGKPPRS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AE
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA