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The map label for this gene is qor [H]

Identifier: 154247795

GI number: 154247795

Start: 4290277

End: 4291251

Strand: Reverse

Name: qor [H]

Synonym: Xaut_3872

Alternate gene names: 154247795

Gene position: 4291251-4290277 (Counterclockwise)

Preceding gene: 154247796

Following gene: 154247793

Centisome position: 80.83

GC content: 66.77

Gene sequence:

>975_bases
ATGGTCCATGCGGTTCGGGTGCATCAGACGGGCGGTCCCGAGGTGCTGGCCTATGAGGCGGTCGAGGTGCCTCCCCCCGG
GCGCGGCGAAGTGCAGATTCGCCAGACCGCCATCGGCCTCAATTTCATCGACGTTTATTTCCGCACCGGCCTCTACAAGG
CCGCGAGCCTTCCCTTCATCCCCGGTAACGAGGGCGCCGGCGTGGTGGAGGCCGTGGGGCCGGACGTGAACGATTTCCAT
CCCGGCGACCGGGTCGCCTATGCCAGCGCCATCGGCGCCTATGCCGAGGTGCGCAACGTGCCGGCCGCCGTGCTGCTGCA
CCTGCCCGCCTCCATCGACGACCAGACCGCCGCCGCCATGATGCTGAAGGGCATGACGGCGCAGTATCTCGTGCGCCGCA
CCCATCACATCAAGCCGGGCGACGTGATTCTGGTGCAGGCGGCAGCCGGCGGCGTGGGGCTCATCCTGTGCCAGTGGGCC
AAGCACCTGGGCGCCACTGTCATCGGCACCGTGGGCTCCAAGGACAAGGCGGAGCTGGCCCTGTCCCACGGCTGCGACGA
GGTGATTCTCTACCGGGACGAGGACTTCGTGCACCGGGTGAAGGAGATCACCGCCGGCAAGCTGTGCGACGTGGTCTATG
ACGGGGTGGGACAGGCGACCTATCCCGCCTCCCTCGACTGCCTGAAACCGCTGGGCCTGTGGGTCAGCTTCGGCAACGCC
TCCGGTGCCATCAAGAATTTCGACCTGCTCCAGCTGTCCCAGAAGGGCTCGCTGTTCGCCACCCGTCCGACCCTCGCCAC
CTTCGTGGCCAAGCGCCATGACCTGATCGCCACCGCCAACGACCTGTTCGAGGCGGTGCTGACCGGAGCGGTGAAGATCC
CGGTCCACCAGACCTATGCGCTGAAGGACGTGCAGAAGGCCCACAAGGACCTCGAATCACGCAAGACCACCGGCTCCACC
CTGCTGCTGCCGTAG

Upstream 100 bases:

>100_bases
GCGCCATCCTGAAGGTTTCCGGCGGGCGCTGAGGGTGCTTGCGGGCGTCCCGCGCCGGCCTATGATCCCGGCGTCTCGGC
AGGAAAAGGGGTCTGGCGTC

Downstream 100 bases:

>100_bases
GCTGCCGGCTTTCTAGCGTGGCGCCGCGGCATCCATGAGATGGCGCGCGGCATAGAGTTCCGGATAGAGCCGGTTGCGGA
ACTGGCTCGCCGCCGGCTCA

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MVHAVRVHQTGGPEVLAYEAVEVPPPGRGEVQIRQTAIGLNFIDVYFRTGLYKAASLPFIPGNEGAGVVEAVGPDVNDFH
PGDRVAYASAIGAYAEVRNVPAAVLLHLPASIDDQTAAAMMLKGMTAQYLVRRTHHIKPGDVILVQAAAGGVGLILCQWA
KHLGATVIGTVGSKDKAELALSHGCDEVILYRDEDFVHRVKEITAGKLCDVVYDGVGQATYPASLDCLKPLGLWVSFGNA
SGAIKNFDLLQLSQKGSLFATRPTLATFVAKRHDLIATANDLFEAVLTGAVKIPVHQTYALKDVQKAHKDLESRKTTGST
LLLP

Sequences:

>Translated_324_residues
MVHAVRVHQTGGPEVLAYEAVEVPPPGRGEVQIRQTAIGLNFIDVYFRTGLYKAASLPFIPGNEGAGVVEAVGPDVNDFH
PGDRVAYASAIGAYAEVRNVPAAVLLHLPASIDDQTAAAMMLKGMTAQYLVRRTHHIKPGDVILVQAAAGGVGLILCQWA
KHLGATVIGTVGSKDKAELALSHGCDEVILYRDEDFVHRVKEITAGKLCDVVYDGVGQATYPASLDCLKPLGLWVSFGNA
SGAIKNFDLLQLSQKGSLFATRPTLATFVAKRHDLIATANDLFEAVLTGAVKIPVHQTYALKDVQKAHKDLESRKTTGST
LLLP
>Mature_324_residues
MVHAVRVHQTGGPEVLAYEAVEVPPPGRGEVQIRQTAIGLNFIDVYFRTGLYKAASLPFIPGNEGAGVVEAVGPDVNDFH
PGDRVAYASAIGAYAEVRNVPAAVLLHLPASIDDQTAAAMMLKGMTAQYLVRRTHHIKPGDVILVQAAAGGVGLILCQWA
KHLGATVIGTVGSKDKAELALSHGCDEVILYRDEDFVHRVKEITAGKLCDVVYDGVGQATYPASLDCLKPLGLWVSFGNA
SGAIKNFDLLQLSQKGSLFATRPTLATFVAKRHDLIATANDLFEAVLTGAVKIPVHQTYALKDVQKAHKDLESRKTTGST
LLLP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=327, Percent_Identity=29.6636085626911, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI13236495, Length=327, Percent_Identity=29.6636085626911, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI194239676, Length=204, Percent_Identity=36.2745098039216, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI18379349, Length=312, Percent_Identity=29.8076923076923, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI22538446, Length=330, Percent_Identity=29.0909090909091, Blast_Score=111, Evalue=8e-25,
Organism=Homo sapiens, GI22538444, Length=330, Percent_Identity=29.0909090909091, Blast_Score=111, Evalue=8e-25,
Organism=Homo sapiens, GI24308257, Length=343, Percent_Identity=28.2798833819242, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI28557745, Length=222, Percent_Identity=33.3333333333333, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI47519420, Length=327, Percent_Identity=25.9938837920489, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI197927207, Length=188, Percent_Identity=24.468085106383, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1790485, Length=329, Percent_Identity=51.9756838905775, Blast_Score=322, Evalue=2e-89,
Organism=Caenorhabditis elegans, GI17507255, Length=323, Percent_Identity=26.9349845201238, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17556000, Length=202, Percent_Identity=31.1881188118812, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=322, Percent_Identity=35.4037267080745, Blast_Score=191, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6319621, Length=345, Percent_Identity=25.5072463768116, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324486, Length=333, Percent_Identity=25.5255255255255, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323961, Length=333, Percent_Identity=24.9249249249249, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34549; Mature: 34549

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVHAVRVHQTGGPEVLAYEAVEVPPPGRGEVQIRQTAIGLNFIDVYFRTGLYKAASLPFI
CCEEEEEECCCCCCEEEEEEEECCCCCCCCEEEEEEEECCHHHHHHHHHCCHHHCCCCCC
PGNEGAGVVEAVGPDVNDFHPGDRVAYASAIGAYAEVRNVPAAVLLHLPASIDDQTAAAM
CCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHH
MLKGMTAQYLVRRTHHIKPGDVILVQAAAGGVGLILCQWAKHLGATVIGTVGSKDKAELA
HHHCCHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHH
LSHGCDEVILYRDEDFVHRVKEITAGKLCDVVYDGVGQATYPASLDCLKPLGLWVSFGNA
HHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCEEEEEECCC
SGAIKNFDLLQLSQKGSLFATRPTLATFVAKRHDLIATANDLFEAVLTGAVKIPVHQTYA
CCCCCCCCEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCHHH
LKDVQKAHKDLESRKTTGSTLLLP
HHHHHHHHHHHHHHCCCCCEEECC
>Mature Secondary Structure
MVHAVRVHQTGGPEVLAYEAVEVPPPGRGEVQIRQTAIGLNFIDVYFRTGLYKAASLPFI
CCEEEEEECCCCCCEEEEEEEECCCCCCCCEEEEEEEECCHHHHHHHHHCCHHHCCCCCC
PGNEGAGVVEAVGPDVNDFHPGDRVAYASAIGAYAEVRNVPAAVLLHLPASIDDQTAAAM
CCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHH
MLKGMTAQYLVRRTHHIKPGDVILVQAAAGGVGLILCQWAKHLGATVIGTVGSKDKAELA
HHHCCHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHH
LSHGCDEVILYRDEDFVHRVKEITAGKLCDVVYDGVGQATYPASLDCLKPLGLWVSFGNA
HHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCEEEEEECCC
SGAIKNFDLLQLSQKGSLFATRPTLATFVAKRHDLIATANDLFEAVLTGAVKIPVHQTYA
CCCCCCCCEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCHHH
LKDVQKAHKDLESRKTTGSTLLLP
HHHHHHHHHHHHHHCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]