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The map label for this gene is glpX

Identifier: 154247448

GI number: 154247448

Start: 3924277

End: 3925266

Strand: Reverse

Name: glpX

Synonym: Xaut_3520

Alternate gene names: 154247448

Gene position: 3925266-3924277 (Counterclockwise)

Preceding gene: 154247449

Following gene: 154247442

Centisome position: 73.94

GC content: 69.29

Gene sequence:

>990_bases
ATGCGCGTTGCCCGGATGCCCCAGGTCCTCGACCGTCGCCTGTCCCTGGACATGGCTCAGGTGACCGAACGCTGCGCGGT
GGCCGCCGCCCGGCTGCGCGGCCGCGGCGACGAGCAGGCCGCCGACCTTGCCGCCATGGCGGCCTGCCACCGGGAGCTCA
GCCTCATTCCGGTCTCCGGCACCGTGGTGATCGGCGAGGGCATCGAGGACGAATGCGAGCAGCTCTTCGTCGGCGAAAAG
CTGGGCGCCGGCGGTGCCGAGGTGGACCTCGCCGTTGACGCGCTGGAAGGCTCCACGCTCTGCGCCAAGAACATGGAAGG
CTCGCTCTGCGTGCTGGTGATCGCCGAGCGCGGCTCCCTGCTGAAGGTGCCCGACGCCTACATGGAGAAGCTGGCGATCG
GCCCCGGCTATCCGGAAGGCATCGTCTCCCTCGCCCAGACCCCGCAGGAGAACATTCAGGCGCTGGCGGACGCCAAGGGC
GTGCCGACCTCCGAGATCACCGCCCTCATCCTCGATCGTCCGCGCCATGCGCCGCTGGTGGAGGCTGTGCGCAAGACCGG
CGCCGCCATCAAGCTCATCACCGACGGCGACGTGGCGGGAGTGATCCACACCACCAATCCGCACGAGAGTGGCATCGACA
TCTATCTCGGCCTCGGCGGCGCGGCCGAGGGCATCCTGGCGGCGGCGGCCCTGCGCTGCATCGGCGGCCAGATGGAAGGC
CGCCTGGTGCTCGACACCGAGAAGAAGCGAGCCCAGGCCAAGACCCTCGGCATCCGCGACGGCGCCAAGATCTACAAGCT
GGAAGAAATGGTGCGCGGCGACTGCCTGGTGGCCGCCACCGGCGTCACCGACGGCGCGCTCCTGAAGGGCGTGCGCTTCA
GCCGCGAGGTGATCGAAACCGACACCATCGTGCTGCGCGCGGCCACCGGCACGGTGCGCCGGATAACCACCGAGCACCGC
GACTTCCGCAAATTCCGTATGGAAAGCTGA

Upstream 100 bases:

>100_bases
CCACGGAAGAAGCCGTGCGCCGCGCCATTGCCGCCATCGAGGCCGACGGGGTCATCTCTGCATTGCCGCAGGTGATCCGA
ATCGAGAAGGATTGACGGCC

Downstream 100 bases:

>100_bases
AAGGACGCCCGAACGCCGCCGCGCGTCAACTCAGACCATCAGCCTCGGGCTTCGGGCGTTCCCAAGTTGCGAACCTTCAA
ACCGGTCGCGGGAATGTCCG

Product: fructose 1,6-bisphosphatase II

Products: NA

Alternate protein names: FBPase class 2; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2 [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MRVARMPQVLDRRLSLDMAQVTERCAVAAARLRGRGDEQAADLAAMAACHRELSLIPVSGTVVIGEGIEDECEQLFVGEK
LGAGGAEVDLAVDALEGSTLCAKNMEGSLCVLVIAERGSLLKVPDAYMEKLAIGPGYPEGIVSLAQTPQENIQALADAKG
VPTSEITALILDRPRHAPLVEAVRKTGAAIKLITDGDVAGVIHTTNPHESGIDIYLGLGGAAEGILAAAALRCIGGQMEG
RLVLDTEKKRAQAKTLGIRDGAKIYKLEEMVRGDCLVAATGVTDGALLKGVRFSREVIETDTIVLRAATGTVRRITTEHR
DFRKFRMES

Sequences:

>Translated_329_residues
MRVARMPQVLDRRLSLDMAQVTERCAVAAARLRGRGDEQAADLAAMAACHRELSLIPVSGTVVIGEGIEDECEQLFVGEK
LGAGGAEVDLAVDALEGSTLCAKNMEGSLCVLVIAERGSLLKVPDAYMEKLAIGPGYPEGIVSLAQTPQENIQALADAKG
VPTSEITALILDRPRHAPLVEAVRKTGAAIKLITDGDVAGVIHTTNPHESGIDIYLGLGGAAEGILAAAALRCIGGQMEG
RLVLDTEKKRAQAKTLGIRDGAKIYKLEEMVRGDCLVAATGVTDGALLKGVRFSREVIETDTIVLRAATGTVRRITTEHR
DFRKFRMES
>Mature_329_residues
MRVARMPQVLDRRLSLDMAQVTERCAVAAARLRGRGDEQAADLAAMAACHRELSLIPVSGTVVIGEGIEDECEQLFVGEK
LGAGGAEVDLAVDALEGSTLCAKNMEGSLCVLVIAERGSLLKVPDAYMEKLAIGPGYPEGIVSLAQTPQENIQALADAKG
VPTSEITALILDRPRHAPLVEAVRKTGAAIKLITDGDVAGVIHTTNPHESGIDIYLGLGGAAEGILAAAALRCIGGQMEG
RLVLDTEKKRAQAKTLGIRDGAKIYKLEEMVRGDCLVAATGVTDGALLKGVRFSREVIETDTIVLRAATGTVRRITTEHR
DFRKFRMES

Specific function: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate. Can functionally substitute for the FBPase class 3 (Fbp) of B.subtilis [H]

COG id: COG1494

COG function: function code G; Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 2 family [H]

Homologues:

Organism=Escherichia coli, GI1790360, Length=328, Percent_Identity=39.0243902439024, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI1789298, Length=324, Percent_Identity=33.9506172839506, Blast_Score=167, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004464 [H]

Pfam domain/function: PF03320 FBPase_glpX [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 34904; Mature: 34904

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVARMPQVLDRRLSLDMAQVTERCAVAAARLRGRGDEQAADLAAMAACHRELSLIPVSG
CCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEECC
TVVIGEGIEDECEQLFVGEKLGAGGAEVDLAVDALEGSTLCAKNMEGSLCVLVIAERGSL
EEEECCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEEECCCCCCEEEEEEECCCCE
LKVPDAYMEKLAIGPGYPEGIVSLAQTPQENIQALADAKGVPTSEITALILDRPRHAPLV
EECCHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHEEEECCCCCCHHH
EAVRKTGAAIKLITDGDVAGVIHTTNPHESGIDIYLGLGGAAEGILAAAALRCIGGQMEG
HHHHHCCCEEEEEECCCEEEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCC
RLVLDTEKKRAQAKTLGIRDGAKIYKLEEMVRGDCLVAATGVTDGALLKGVRFSREVIET
EEEEECHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHCC
DTIVLRAATGTVRRITTEHRDFRKFRMES
CEEEEEECCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRVARMPQVLDRRLSLDMAQVTERCAVAAARLRGRGDEQAADLAAMAACHRELSLIPVSG
CCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEECC
TVVIGEGIEDECEQLFVGEKLGAGGAEVDLAVDALEGSTLCAKNMEGSLCVLVIAERGSL
EEEECCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEEECCCCCCEEEEEEECCCCE
LKVPDAYMEKLAIGPGYPEGIVSLAQTPQENIQALADAKGVPTSEITALILDRPRHAPLV
EECCHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHEEEECCCCCCHHH
EAVRKTGAAIKLITDGDVAGVIHTTNPHESGIDIYLGLGGAAEGILAAAALRCIGGQMEG
HHHHHCCCEEEEEECCCEEEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCC
RLVLDTEKKRAQAKTLGIRDGAKIYKLEEMVRGDCLVAATGVTDGALLKGVRFSREVIET
EEEEECHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHCC
DTIVLRAATGTVRRITTEHRDFRKFRMES
CEEEEEECCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8423140; 9353933; 9384377 [H]