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The map label for this gene is lldR [H]

Identifier: 154247300

GI number: 154247300

Start: 3758724

End: 3759623

Strand: Reverse

Name: lldR [H]

Synonym: Xaut_3372

Alternate gene names: 154247300

Gene position: 3759623-3758724 (Counterclockwise)

Preceding gene: 154247303

Following gene: 154247299

Centisome position: 70.82

GC content: 70.44

Gene sequence:

>900_bases
ATGTATGGAACTCGCCACCATGGCCGGGGCCATACCGGCAGGCCGGAATCAGTAAGGGAGAAGCGGGTGCGCAGTCGCCT
GAAGTCCGCCGCCCAGAGGGCTGCCCAGGAAGGCGCCCAGGGCAACCCGCACGGCGCCTCCCCGGCAGGTTCTCACGCAA
GCACCCATCCGCCCGGCGGCCGCGCCGCCGGCACGCTCGTGGCCCAGGTCAGCGACGCGCTGCGGCAGATGATCCTGTCC
GGCGAGTTTCCGCCCGGCGCCAAGCTGCCCAGCGAGGCCCAGCTCACCCAGGCCCATGGCGTCAGCCGCACCGTGGTGCG
CGAGGCGGTGGCGGCCCTGCGTTCGGACGGGCTGGTGGAAGCGCGCCAGGGCGCGGGCGTGTTCGTGCTCGACCACGCCA
CCACCACCCCGCTCCTGTCCTTCCAGAATGTTGATGGCGCACGCGTTTCCTCCACCATAGAGCTGCTGGAGCTGCGCACC
GGCGTGGAGGTGGAGGCCGCGGGGCTGGCCGCCGCGCGCCGCTCCCCGGCGCAGGAAGAGGTGATTTTCGAGCGGCATTT
CGCGGTGCGGACCGCGCTGGACGAAGGCCGCTCAACGGTGGAGGCGGACCTTGCCCTGCACCTCGCCATCGCCGACGCCA
CCAACAACCCGCGCTTCCGCGAATTCCTCGCCATGATCGGCCGCGACGCCATTCCCCGCGCGGTGCTGGAGGGCGAAGGC
CAGAGCGTGGAGCGCGTGTCGTCCTACATCAAGATGATCGACGAGGAGCACCAGCGCATCGTCGTGGCCATCTCCCGCGG
CGACGAGGATGCGGCGCGCGAGGCCATGCGCGTCCACCTGCGCGGTAGCCAGGCGCGCTATCGCACGCTGCTGCAGACCC
GGCGCAAACATGTAATATAA

Upstream 100 bases:

>100_bases
CCTCTTGGCTGGATCTTGCGCGCCCGCATCCGGCTGGAAAATGATAAGTCATCATACATGTATGGACATTCCGGTCAATA
TTCGGCCAAACTTGACAGAC

Downstream 100 bases:

>100_bases
GTTATTGACGCCTGTTGGCCATACATGTATGACAACTCTGCCCTGGTTATATGGCAGAGGAGCCGTGATGAACCCGCAGG
ACATAAAGACCGCGCTCGGC

Product: GntR domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MYGTRHHGRGHTGRPESVREKRVRSRLKSAAQRAAQEGAQGNPHGASPAGSHASTHPPGGRAAGTLVAQVSDALRQMILS
GEFPPGAKLPSEAQLTQAHGVSRTVVREAVAALRSDGLVEARQGAGVFVLDHATTTPLLSFQNVDGARVSSTIELLELRT
GVEVEAAGLAAARRSPAQEEVIFERHFAVRTALDEGRSTVEADLALHLAIADATNNPRFREFLAMIGRDAIPRAVLEGEG
QSVERVSSYIKMIDEEHQRIVVAISRGDEDAAREAMRVHLRGSQARYRTLLQTRRKHVI

Sequences:

>Translated_299_residues
MYGTRHHGRGHTGRPESVREKRVRSRLKSAAQRAAQEGAQGNPHGASPAGSHASTHPPGGRAAGTLVAQVSDALRQMILS
GEFPPGAKLPSEAQLTQAHGVSRTVVREAVAALRSDGLVEARQGAGVFVLDHATTTPLLSFQNVDGARVSSTIELLELRT
GVEVEAAGLAAARRSPAQEEVIFERHFAVRTALDEGRSTVEADLALHLAIADATNNPRFREFLAMIGRDAIPRAVLEGEG
QSVERVSSYIKMIDEEHQRIVVAISRGDEDAAREAMRVHLRGSQARYRTLLQTRRKHVI
>Mature_299_residues
MYGTRHHGRGHTGRPESVREKRVRSRLKSAAQRAAQEGAQGNPHGASPAGSHASTHPPGGRAAGTLVAQVSDALRQMILS
GEFPPGAKLPSEAQLTQAHGVSRTVVREAVAALRSDGLVEARQGAGVFVLDHATTTPLLSFQNVDGARVSSTIELLELRT
GVEVEAAGLAAARRSPAQEEVIFERHFAVRTALDEGRSTVEADLALHLAIADATNNPRFREFLAMIGRDAIPRAVLEGEG
QSVERVSSYIKMIDEEHQRIVVAISRGDEDAAREAMRVHLRGSQARYRTLLQTRRKHVI

Specific function: May be a regulatory protein for the LCT genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790032, Length=223, Percent_Identity=32.2869955156951, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790780, Length=234, Percent_Identity=32.0512820512821, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786303, Length=224, Percent_Identity=30.8035714285714, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI48994961, Length=220, Percent_Identity=30.4545454545455, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI87082208, Length=224, Percent_Identity=27.6785714285714, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789353, Length=221, Percent_Identity=28.5067873303167, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 32290; Mature: 32290

Theoretical pI: Translated: 10.47; Mature: 10.47

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYGTRHHGRGHTGRPESVREKRVRSRLKSAAQRAAQEGAQGNPHGASPAGSHASTHPPGG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
RAAGTLVAQVSDALRQMILSGEFPPGAKLPSEAQLTQAHGVSRTVVREAVAALRSDGLVE
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCEE
ARQGAGVFVLDHATTTPLLSFQNVDGARVSSTIELLELRTGVEVEAAGLAAARRSPAQEE
CCCCCCEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHH
VIFERHFAVRTALDEGRSTVEADLALHLAIADATNNPRFREFLAMIGRDAIPRAVLEGEG
HHHHHHHHHHHHHHHCCHHHHHHHEEEEEEECCCCCHHHHHHHHHHCCCCCCHHHHCCCC
QSVERVSSYIKMIDEEHQRIVVAISRGDEDAAREAMRVHLRGSQARYRTLLQTRRKHVI
CHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYGTRHHGRGHTGRPESVREKRVRSRLKSAAQRAAQEGAQGNPHGASPAGSHASTHPPGG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
RAAGTLVAQVSDALRQMILSGEFPPGAKLPSEAQLTQAHGVSRTVVREAVAALRSDGLVE
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCEE
ARQGAGVFVLDHATTTPLLSFQNVDGARVSSTIELLELRTGVEVEAAGLAAARRSPAQEE
CCCCCCEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHH
VIFERHFAVRTALDEGRSTVEADLALHLAIADATNNPRFREFLAMIGRDAIPRAVLEGEG
HHHHHHHHHHHHHHHCCHHHHHHHEEEEEEECCCCCHHHHHHHHHHCCCCCCHHHHCCCC
QSVERVSSYIKMIDEEHQRIVVAISRGDEDAAREAMRVHLRGSQARYRTLLQTRRKHVI
CHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8407843; 8041620; 9278503 [H]