BacMap

Definition	Xanthobacter autotrophicus Py2 chromosome, complete genome.
Accession	NC_009720
Length	5,308,934

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The map label for this gene is fabG [H]

Identifier: 154246867

GI number: 154246867

Start: 3256766

End: 3257479

Strand: Reverse

Name: fabG [H]

Synonym: Xaut_2932

Alternate gene names: 154246867

Gene position: 3257479-3256766 (Counterclockwise)

Preceding gene: 154246868

Following gene: 154246864

Centisome position: 61.36

GC content: 68.91

Gene sequence:

>714_bases
ATGCAACGGACCTTCCTCATCACCGGCGCCAGCAAGGGCATCGGCCTCGCACTCTCCCTGCGCCTCGCGGCGCAGGGCCA
TCGCATCATCGGCATCGCGCGACACCGCAGCGACGGCTTTCCCGGAACGCTCCACGCGCTCGATCTCAGCACGCAGGATG
CGGGCAGGCGGCTGGCGCAGATCGTCGCTGCCGATCCGGTCGACGGCATCGTCAACAATGTCGGGCTGGTGCGCGCCGAG
CCACTCGGGGCGATCGAGGCCGAAACCCTCGACGAGGTGCTGCGGACCAATCTCCATCCTGCGCTCGCCGCCGTCCAGGC
GGCGGTGCCGGGCATGACCGCGCGCGGCTGGGGACGCATCGTCAATATCTCCAGCCTCACCATCCTCGGCGCCGTCGAGC
GCACCTCCTACGCCGCAGCCAAGGCGGCGCTGGTGAGCTTCACCCGCAGTTGGGCGCTGGAGCTTGCGACCTCCGGCATC
ACCGTCAATGCGGTTGCGCCGGGGCCGACCGAGACCGAACTGTTCCGCGCCAACAACGCGCCGGGAAGCGCGGGCGAGGC
GCGCTACCTCTCCGGCGTGCCGATGAAGCGGTTCGGAACCCCGCAGGAAATCGCCGCCGCCGTCGCCTTCCTGATGTCAG
ACGATGCAGCCTTCATCACCGGCCAGACGTTGCATGTGGACGGAGGCGCCTCGATCGGAAAGGCGTCGTTCTGA

Upstream 100 bases:

>100_bases
CGGCGGACATGCTGCCCGCCCTTCGCCGCGCCGCGGGTGCCACCGCCGCCTGATCCGCCCAGACATGCCCCGCCCATGAG
AGCGGGGGGAGAACCCACCC

Downstream 100 bases:

>100_bases
CCTTCGGCCAATGTCCGGACTGGGAGGCGCAGCGAGGGTCTGCTCCCGGCGCGCGACAGACTGCCCAGGCATTCACAGCC
GCAGCGTCTCGAACTCGATC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MQRTFLITGASKGIGLALSLRLAAQGHRIIGIARHRSDGFPGTLHALDLSTQDAGRRLAQIVAADPVDGIVNNVGLVRAE
PLGAIEAETLDEVLRTNLHPALAAVQAAVPGMTARGWGRIVNISSLTILGAVERTSYAAAKAALVSFTRSWALELATSGI
TVNAVAPGPTETELFRANNAPGSAGEARYLSGVPMKRFGTPQEIAAAVAFLMSDDAAFITGQTLHVDGGASIGKASF

Sequences:

>Translated_237_residues
MQRTFLITGASKGIGLALSLRLAAQGHRIIGIARHRSDGFPGTLHALDLSTQDAGRRLAQIVAADPVDGIVNNVGLVRAE
PLGAIEAETLDEVLRTNLHPALAAVQAAVPGMTARGWGRIVNISSLTILGAVERTSYAAAKAALVSFTRSWALELATSGI
TVNAVAPGPTETELFRANNAPGSAGEARYLSGVPMKRFGTPQEIAAAVAFLMSDDAAFITGQTLHVDGGASIGKASF
>Mature_237_residues
MQRTFLITGASKGIGLALSLRLAAQGHRIIGIARHRSDGFPGTLHALDLSTQDAGRRLAQIVAADPVDGIVNNVGLVRAE
PLGAIEAETLDEVLRTNLHPALAAVQAAVPGMTARGWGRIVNISSLTILGAVERTSYAAAKAALVSFTRSWALELATSGI
TVNAVAPGPTETELFRANNAPGSAGEARYLSGVPMKRFGTPQEIAAAVAFLMSDDAAFITGQTLHVDGGASIGKASF

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=247, Percent_Identity=32.7935222672065, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI7705925, Length=237, Percent_Identity=33.7552742616034, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI66933014, Length=224, Percent_Identity=29.4642857142857, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI40254992, Length=245, Percent_Identity=31.4285714285714, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI19923817, Length=174, Percent_Identity=35.632183908046, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI32483357, Length=246, Percent_Identity=30.8943089430894, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI7657478, Length=218, Percent_Identity=33.0275229357798, Blast_Score=84, Evalue=8e-17,
Organism=Homo sapiens, GI59889578, Length=225, Percent_Identity=30.2222222222222, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI5031737, Length=247, Percent_Identity=28.7449392712551, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI126723750, Length=244, Percent_Identity=28.2786885245902, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI223718074, Length=191, Percent_Identity=31.9371727748691, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787335, Length=235, Percent_Identity=40.8510638297872, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI2367175, Length=251, Percent_Identity=32.6693227091633, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1790717, Length=241, Percent_Identity=30.2904564315353, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI87082100, Length=250, Percent_Identity=31.2, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1786812, Length=242, Percent_Identity=29.7520661157025, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788459, Length=256, Percent_Identity=32.03125, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1789208, Length=240, Percent_Identity=31.25, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1786701, Length=184, Percent_Identity=33.695652173913, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87082160, Length=240, Percent_Identity=28.3333333333333, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI2367365, Length=250, Percent_Identity=31.6, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787905, Length=241, Percent_Identity=29.4605809128631, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789378, Length=254, Percent_Identity=25.9842519685039, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1789057, Length=260, Percent_Identity=25.3846153846154, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787820, Length=224, Percent_Identity=26.7857142857143, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=242, Percent_Identity=33.4710743801653, Blast_Score=110, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17560676, Length=244, Percent_Identity=30.327868852459, Blast_Score=100, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17555706, Length=237, Percent_Identity=33.7552742616034, Blast_Score=100, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI25147288, Length=247, Percent_Identity=33.6032388663968, Blast_Score=100, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI71994604, Length=249, Percent_Identity=31.3253012048193, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=30.6772908366534, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17562910, Length=260, Percent_Identity=28.4615384615385, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=29.6153846153846, Blast_Score=87, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17551412, Length=267, Percent_Identity=29.9625468164794, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=260, Percent_Identity=28.4615384615385, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17538480, Length=261, Percent_Identity=29.5019157088123, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=259, Percent_Identity=30.5019305019305, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=258, Percent_Identity=28.6821705426357, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17544670, Length=263, Percent_Identity=26.615969581749, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17565030, Length=258, Percent_Identity=28.2945736434109, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=257, Percent_Identity=29.5719844357977, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=257, Percent_Identity=26.8482490272374, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17561402, Length=245, Percent_Identity=24.4897959183673, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=258, Percent_Identity=28.2945736434109, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=258, Percent_Identity=25.968992248062, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=257, Percent_Identity=26.8482490272374, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17560220, Length=256, Percent_Identity=28.515625, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=258, Percent_Identity=26.7441860465116, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=259, Percent_Identity=27.027027027027, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=201, Percent_Identity=31.3432835820896, Blast_Score=66, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24643142, Length=249, Percent_Identity=32.1285140562249, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI23397609, Length=247, Percent_Identity=33.6032388663968, Blast_Score=97, Evalue=8e-21,
Organism=Drosophila melanogaster, GI28571526, Length=247, Percent_Identity=32.7935222672065, Blast_Score=95, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=33.2, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24644339, Length=247, Percent_Identity=31.1740890688259, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21355319, Length=242, Percent_Identity=29.3388429752066, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=28.7449392712551, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24644337, Length=174, Percent_Identity=34.4827586206897, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21358495, Length=191, Percent_Identity=30.8900523560209, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 24475; Mature: 24475

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRTFLITGASKGIGLALSLRLAAQGHRIIGIARHRSDGFPGTLHALDLSTQDAGRRLAQ
CCEEEEEECCCCCCEEEEEEEEECCCCEEEEEEEECCCCCCCEEEEEECCCHHHHHHHHH
IVAADPVDGIVNNVGLVRAEPLGAIEAETLDEVLRTNLHPALAAVQAAVPGMTARGWGRI
HHHCCCHHHHHHCCCEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCEE
VNISSLTILGAVERTSYAAAKAALVSFTRSWALELATSGITVNAVAPGPTETELFRANNA
EEECEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEECCCCCCCEEEECCCC
PGSAGEARYLSGVPMKRFGTPQEIAAAVAFLMSDDAAFITGQTLHVDGGASIGKASF
CCCCCCCCEECCCCHHHCCCHHHHHHHHHHHHCCCCEEEECCEEEECCCCCCCCCCC
>Mature Secondary Structure
MQRTFLITGASKGIGLALSLRLAAQGHRIIGIARHRSDGFPGTLHALDLSTQDAGRRLAQ
CCEEEEEECCCCCCEEEEEEEEECCCCEEEEEEEECCCCCCCEEEEEECCCHHHHHHHHH
IVAADPVDGIVNNVGLVRAEPLGAIEAETLDEVLRTNLHPALAAVQAAVPGMTARGWGRI
HHHCCCHHHHHHCCCEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCEE
VNISSLTILGAVERTSYAAAKAALVSFTRSWALELATSGITVNAVAPGPTETELFRANNA
EEECEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEECCCCCCCEEEECCCC
PGSAGEARYLSGVPMKRFGTPQEIAAAVAFLMSDDAAFITGQTLHVDGGASIGKASF
CCCCCCCCEECCCCHHHCCCHHHHHHHHHHHHCCCCEEEECCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]