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The map label for this gene is blh [H]

Identifier: 154246828

GI number: 154246828

Start: 3215580

End: 3216485

Strand: Reverse

Name: blh [H]

Synonym: Xaut_2892

Alternate gene names: 154246828

Gene position: 3216485-3215580 (Counterclockwise)

Preceding gene: 154246829

Following gene: 154246827

Centisome position: 60.59

GC content: 62.58

Gene sequence:

>906_bases
ATGCCCGCCTCGTCTTCGCCTCTGAAAGGCAACCCTGTCGTGAAGGGCTTCTTCGAGAAGCGCACGTCTAGCGTCCAGTA
TGTCGTCGCCGATCCGGAGACGAAGCGCGCCGCCATAATCGACCCGGTGCTGGACTTCGATCCGAAGTCCGGCGCTACGG
CCACTCACTCGGCCGATCAGCTCCTCGCGCATATCGACCAGGAGGACTACACGCTGGAGTGGATTTTGGACACCCATCCG
CATGCCGATCATTTCTCGGCGGCCGGCTACCTCAAGGACAAGACAGCCGTCCCGACCGCCATCGGCGAGAAGGTCGTCGA
GATCCAGAAGCTCTGGAAGGGGATCTACAACCTGCCCGACAGCTTCCCGCCAGACGGCTCGCAATGGAACCGGCTCTTCG
CCGACGGCGAACGTTTCAAGATCGGCAACATGGACGTCGAGGTGGTGTTCACGCCGGGGCACACGCTCGCCTCGATCGCC
TACGTGGTCGGCGACGCCGCCTTCATCCACGACACTATCTTCATGCCGGATGGCGGCACAGCCCGGGCCGACTTCCCTGG
CGGCTCAGCAAAGGTGCTGTGGAACAGTATTCAACGCATCATGGCGCTGCCCGACGACACCCGCTTGTTCACCGGGCACG
ACTACTGCCCTGGCGGTCGAAAGCCGGAATGGGAAAGCACAGTGGCTGAGCAGAGGGCCAGGAACACGCACCTCGTAAAG
GCAAGAACGGAAGAGGAGTTCGTGGCCCTGCGCGAGAAGCGCGACCGCGAGCTGCCTATGCCGAAGCTCATCCTGCACTC
CCTGCAGGTGAACATCCAGGGCGGTCGGCTGCCTGAGCCCGAGGAAAACGGCATACGTTATCTCAAGATCCCCCTCGATG
CGCTCGACGCACCGTGGGACGAGTGA

Upstream 100 bases:

>100_bases
TCGCCGGCCTCGTGATCGTGGTCGGCCTCTACATTATTGCCCGAGGGCTCCTCGCGCTGACAGCCACTCAGCCATGAATC
AATCGAAAGGAGCAAACTGC

Downstream 100 bases:

>100_bases
AGGAGCCAATCATGACGACGAAAAGTGCAAAGGATCTAGTGGCTGAGGCAAGCCGGGACATCGAGACGCTTTCGGGCCCA
GAAGCAGCGAAGTTGGTGGG

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MPASSSPLKGNPVVKGFFEKRTSSVQYVVADPETKRAAIIDPVLDFDPKSGATATHSADQLLAHIDQEDYTLEWILDTHP
HADHFSAAGYLKDKTAVPTAIGEKVVEIQKLWKGIYNLPDSFPPDGSQWNRLFADGERFKIGNMDVEVVFTPGHTLASIA
YVVGDAAFIHDTIFMPDGGTARADFPGGSAKVLWNSIQRIMALPDDTRLFTGHDYCPGGRKPEWESTVAEQRARNTHLVK
ARTEEEFVALREKRDRELPMPKLILHSLQVNIQGGRLPEPEENGIRYLKIPLDALDAPWDE

Sequences:

>Translated_301_residues
MPASSSPLKGNPVVKGFFEKRTSSVQYVVADPETKRAAIIDPVLDFDPKSGATATHSADQLLAHIDQEDYTLEWILDTHP
HADHFSAAGYLKDKTAVPTAIGEKVVEIQKLWKGIYNLPDSFPPDGSQWNRLFADGERFKIGNMDVEVVFTPGHTLASIA
YVVGDAAFIHDTIFMPDGGTARADFPGGSAKVLWNSIQRIMALPDDTRLFTGHDYCPGGRKPEWESTVAEQRARNTHLVK
ARTEEEFVALREKRDRELPMPKLILHSLQVNIQGGRLPEPEENGIRYLKIPLDALDAPWDE
>Mature_300_residues
PASSSPLKGNPVVKGFFEKRTSSVQYVVADPETKRAAIIDPVLDFDPKSGATATHSADQLLAHIDQEDYTLEWILDTHPH
ADHFSAAGYLKDKTAVPTAIGEKVVEIQKLWKGIYNLPDSFPPDGSQWNRLFADGERFKIGNMDVEVVFTPGHTLASIAY
VVGDAAFIHDTIFMPDGGTARADFPGGSAKVLWNSIQRIMALPDDTRLFTGHDYCPGGRKPEWESTVAEQRARNTHLVKA
RTEEEFVALREKRDRELPMPKLILHSLQVNIQGGRLPEPEENGIRYLKIPLDALDAPWDE

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=271, Percent_Identity=28.0442804428044, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI1787158, Length=186, Percent_Identity=29.5698924731183, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17538952, Length=275, Percent_Identity=28.7272727272727, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI221330176, Length=279, Percent_Identity=28.3154121863799, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI21356335, Length=200, Percent_Identity=28, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24667703, Length=200, Percent_Identity=28, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24667711, Length=200, Percent_Identity=27.5, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 33495; Mature: 33364

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPASSSPLKGNPVVKGFFEKRTSSVQYVVADPETKRAAIIDPVLDFDPKSGATATHSADQ
CCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCEEEECHHHCCCCCCCCCCCCHHHH
LLAHIDQEDYTLEWILDTHPHADHFSAAGYLKDKTAVPTAIGEKVVEIQKLWKGIYNLPD
HHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
SFPPDGSQWNRLFADGERFKIGNMDVEVVFTPGHTLASIAYVVGDAAFIHDTIFMPDGGT
CCCCCCHHHHHHHCCCCEEEECCEEEEEEECCCHHHHHHHHHHHCHHHHEEEEECCCCCC
ARADFPGGSAKVLWNSIQRIMALPDDTRLFTGHDYCPGGRKPEWESTVAEQRARNTHLVK
EECCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCEEEE
ARTEEEFVALREKRDRELPMPKLILHSLQVNIQGGRLPEPEENGIRYLKIPLDALDAPWD
ECCHHHHHHHHHHHCCCCCHHHHHHHHHEEEECCCCCCCCCCCCEEEEEEEHHHCCCCCC
E
C
>Mature Secondary Structure 
PASSSPLKGNPVVKGFFEKRTSSVQYVVADPETKRAAIIDPVLDFDPKSGATATHSADQ
CCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCEEEECHHHCCCCCCCCCCCCHHHH
LLAHIDQEDYTLEWILDTHPHADHFSAAGYLKDKTAVPTAIGEKVVEIQKLWKGIYNLPD
HHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
SFPPDGSQWNRLFADGERFKIGNMDVEVVFTPGHTLASIAYVVGDAAFIHDTIFMPDGGT
CCCCCCHHHHHHHCCCCEEEECCEEEEEEECCCHHHHHHHHHHHCHHHHEEEEECCCCCC
ARADFPGGSAKVLWNSIQRIMALPDDTRLFTGHDYCPGGRKPEWESTVAEQRARNTHLVK
EECCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCEEEE
ARTEEEFVALREKRDRELPMPKLILHSLQVNIQGGRLPEPEENGIRYLKIPLDALDAPWD
ECCHHHHHHHHHHHCCCCCHHHHHHHHHEEEECCCCCCCCCCCCEEEEEEEHHHCCCCCC
E
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]