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The map label for this gene is glpD

Identifier: 154246747

GI number: 154246747

Start: 3128226

End: 3129755

Strand: Direct

Name: glpD

Synonym: Xaut_2808

Alternate gene names: 154246747

Gene position: 3128226-3129755 (Clockwise)

Preceding gene: 154246746

Following gene: 154246748

Centisome position: 58.92

GC content: 70.59

Gene sequence:

>1530_bases
ATGATGCGCCGCCGGGGGGAGGCGGGGATGGAGGAAACCACGCGCGTCTTCGACCTCGCCATCATCGGCGGCGGTATCAA
CGGCGCCGGCATCGCTCGCGATGCGGCCGGGCGCGGCCTTTCCGTCGTGCTGTTCGAGCAGGCGGACCTGGCCTCCGGCA
CCTCGTCCGCCTCCACCAAGCTCATCCATGGCGGGCTGCGCTACCTGGAACATTACGCCTTCCGCCTGGTGCGGGAGGCG
TTGGCCGAACGTGAGGTGCTGTGGGGCATCGCTCCGCACATCATCTGGCCGCTGCGCTTCGTGCTGCCCCACCATGCCGG
CCTGCGCCCGGCGTGGATGCTGCGGCTGGGCCTGTTTCTCTACGACCATCTGGGCGGCCGCCGCCTGCTGCCGCCTACGC
GCACGTTGGACCTGAGGCACGACCCCGCCGGTCTCCCGCTGCGCCCCGGCCTTGGCACGGCGTTCGAATATTCCGACTGC
TGGGTGGAGGATGCCCGCCTCGTGGTGCTCAATGCCCGCGATGCGGCGGACCGGGGCGCCTCCATCCGTCCGCGCACCAA
AGTGGTGGGCGCGCATCGCGTCGATGGCCTGTGGGAGATCGAGGCGGAAGGCATGGCGGGGCGCGAGAGCGTGCGCGCCC
GCGCGCTGGTGGATGCCGCCGGCCCCTGGGCCGGGCAGGTGCTGGATGTGTTGCAGGTGAAGGCGAGCGCGCGCCTGCGC
CTCGTCAAGGGCAGCCACATCGTGGTGCACCGCCTGTTCGCGCACGATCGCTGCTACCTGTTCCAGAATGGTGACGGGCG
CATCGTGTTCGCCATTCCCTATGAGGGCGACTTCACCCTCATCGGCACCACCGACCTCGACTATGAGGGCCGGCCGGAGG
ATGTGGCGGCGAGCCCCGAGGAGGTGGCCTACCTCTGCGCGGCGGCCAGCGAGTATTTCGCCGCCGCGCTCGCGCCGGAG
CAGGTGGTGTGGGCCTATTCCGGCGTGCGCGCCCTGTACGACGACGGCGCGGGCAAGGCGCAGGAAGCAACCCGCGACTA
TGTGCTCGCCCTCGACGCGCCCGACGGCGAGGCGCCGCTGCTGTCGGTCTTCGGCGGCAAGATCACCACCTATCGCCGCC
TTGCCGAGGCCACGCTGGCGCGGCTTGCGCCCCATCTGCCGGTGCTGGGGCCGTCCTTCACGGGCAAGGTGCCGCTGCCG
GGCGGGGATTTCCCGCGGCAGGGTTTCGATCACCTCCTGAAAAGCCTGCGCCGTACCTTTCCCGCCCTCGATCCGGCCCT
GCTCAAGCGCCTCGCACGGGCCTATGGCACATCGACCTTCCGCCTGCTGGAAGGGGTGATGCACGAGGACGACCTCGGCG
ACTGGTTCGGCGCCCACCTGTGCCGCCGCGAGGTCGACTGGCTGATGGACCAGGAATGGGCCATGACCGCCGAGGACGTG
CTGTGGCGTCGCTCGAAGCTCGGCCTGCGCACCCGTCATGAGGAAGCGCGGACGCTCGACGCCTACATGGCCGCCCGGCG
CGGCGGCTGA

Upstream 100 bases:

>100_bases
CCGGCTGTGCCGTCGCGGGTCCGGTAAATGGGTCATGGCCCAGTTGACGCCGCCGCCCGGCGCGGCATGGTCTGGCGGGA
AGGGCGGGAAGTCCGGCGCC

Downstream 100 bases:

>100_bases
AAACAACAATCCGGGAGGAGCTATTGGCCGCCTACATCCTCGCCATCGACCAGGGCACCACCTCCTCCCGCGCCCTGCTG
GTGCGGCGCGACGGCACCAT

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MMRRRGEAGMEETTRVFDLAIIGGGINGAGIARDAAGRGLSVVLFEQADLASGTSSASTKLIHGGLRYLEHYAFRLVREA
LAEREVLWGIAPHIIWPLRFVLPHHAGLRPAWMLRLGLFLYDHLGGRRLLPPTRTLDLRHDPAGLPLRPGLGTAFEYSDC
WVEDARLVVLNARDAADRGASIRPRTKVVGAHRVDGLWEIEAEGMAGRESVRARALVDAAGPWAGQVLDVLQVKASARLR
LVKGSHIVVHRLFAHDRCYLFQNGDGRIVFAIPYEGDFTLIGTTDLDYEGRPEDVAASPEEVAYLCAAASEYFAAALAPE
QVVWAYSGVRALYDDGAGKAQEATRDYVLALDAPDGEAPLLSVFGGKITTYRRLAEATLARLAPHLPVLGPSFTGKVPLP
GGDFPRQGFDHLLKSLRRTFPALDPALLKRLARAYGTSTFRLLEGVMHEDDLGDWFGAHLCRREVDWLMDQEWAMTAEDV
LWRRSKLGLRTRHEEARTLDAYMAARRGG

Sequences:

>Translated_509_residues
MMRRRGEAGMEETTRVFDLAIIGGGINGAGIARDAAGRGLSVVLFEQADLASGTSSASTKLIHGGLRYLEHYAFRLVREA
LAEREVLWGIAPHIIWPLRFVLPHHAGLRPAWMLRLGLFLYDHLGGRRLLPPTRTLDLRHDPAGLPLRPGLGTAFEYSDC
WVEDARLVVLNARDAADRGASIRPRTKVVGAHRVDGLWEIEAEGMAGRESVRARALVDAAGPWAGQVLDVLQVKASARLR
LVKGSHIVVHRLFAHDRCYLFQNGDGRIVFAIPYEGDFTLIGTTDLDYEGRPEDVAASPEEVAYLCAAASEYFAAALAPE
QVVWAYSGVRALYDDGAGKAQEATRDYVLALDAPDGEAPLLSVFGGKITTYRRLAEATLARLAPHLPVLGPSFTGKVPLP
GGDFPRQGFDHLLKSLRRTFPALDPALLKRLARAYGTSTFRLLEGVMHEDDLGDWFGAHLCRREVDWLMDQEWAMTAEDV
LWRRSKLGLRTRHEEARTLDAYMAARRGG
>Mature_509_residues
MMRRRGEAGMEETTRVFDLAIIGGGINGAGIARDAAGRGLSVVLFEQADLASGTSSASTKLIHGGLRYLEHYAFRLVREA
LAEREVLWGIAPHIIWPLRFVLPHHAGLRPAWMLRLGLFLYDHLGGRRLLPPTRTLDLRHDPAGLPLRPGLGTAFEYSDC
WVEDARLVVLNARDAADRGASIRPRTKVVGAHRVDGLWEIEAEGMAGRESVRARALVDAAGPWAGQVLDVLQVKASARLR
LVKGSHIVVHRLFAHDRCYLFQNGDGRIVFAIPYEGDFTLIGTTDLDYEGRPEDVAASPEEVAYLCAAASEYFAAALAPE
QVVWAYSGVRALYDDGAGKAQEATRDYVLALDAPDGEAPLLSVFGGKITTYRRLAEATLARLAPHLPVLGPSFTGKVPLP
GGDFPRQGFDHLLKSLRRTFPALDPALLKRLARAYGTSTFRLLEGVMHEDDLGDWFGAHLCRREVDWLMDQEWAMTAEDV
LWRRSKLGLRTRHEEARTLDAYMAARRGG

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=518, Percent_Identity=31.0810810810811, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI285002231, Length=518, Percent_Identity=31.0810810810811, Blast_Score=174, Evalue=2e-43,
Organism=Escherichia coli, GI2367226, Length=453, Percent_Identity=47.9028697571744, Blast_Score=414, Evalue=1e-116,
Organism=Escherichia coli, GI1788574, Length=403, Percent_Identity=30.272952853598, Blast_Score=99, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI115534726, Length=516, Percent_Identity=26.7441860465116, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17509253, Length=401, Percent_Identity=31.9201995012469, Blast_Score=134, Evalue=9e-32,
Organism=Saccharomyces cerevisiae, GI6322036, Length=557, Percent_Identity=28.5457809694794, Blast_Score=136, Evalue=8e-33,
Organism=Drosophila melanogaster, GI161077125, Length=454, Percent_Identity=31.057268722467, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24653942, Length=454, Percent_Identity=31.057268722467, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24653944, Length=454, Percent_Identity=31.057268722467, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI20130025, Length=454, Percent_Identity=31.057268722467, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24586295, Length=393, Percent_Identity=29.2620865139949, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI19921278, Length=389, Percent_Identity=24.6786632390745, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 56123; Mature: 56123

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRRRGEAGMEETTRVFDLAIIGGGINGAGIARDAAGRGLSVVLFEQADLASGTSSASTK
CCCCCCCCCHHHHHHEEEEEEECCCCCCCCCCHHCCCCCEEEEEEECCCCCCCCCCHHHH
LIHGGLRYLEHYAFRLVREALAEREVLWGIAPHIIWPLRFVLPHHAGLRPAWMLRLGLFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
YDHLGGRRLLPPTRTLDLRHDPAGLPLRPGLGTAFEYSDCWVEDARLVVLNARDAADRGA
HHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCEECCCCEECCCEEEEEECCCCCCCCC
SIRPRTKVVGAHRVDGLWEIEAEGMAGRESVRARALVDAAGPWAGQVLDVLQVKASARLR
CCCCCHHEECCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEE
LVKGSHIVVHRLFAHDRCYLFQNGDGRIVFAIPYEGDFTLIGTTDLDYEGRPEDVAASPE
EEECCEEEEHHHHHCCEEEEEECCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCHH
EVAYLCAAASEYFAAALAPEQVVWAYSGVRALYDDGAGKAQEATRDYVLALDAPDGEAPL
HHHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHCCCCCCHHHCCCCEEEEEECCCCCCCC
LSVFGGKITTYRRLAEATLARLAPHLPVLGPSFTGKVPLPGGDFPRQGFDHLLKSLRRTF
HHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
PALDPALLKRLARAYGTSTFRLLEGVMHEDDLGDWFGAHLCRREVDWLMDQEWAMTAEDV
CCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHH
LWRRSKLGLRTRHEEARTLDAYMAARRGG
HHHHHHCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMRRRGEAGMEETTRVFDLAIIGGGINGAGIARDAAGRGLSVVLFEQADLASGTSSASTK
CCCCCCCCCHHHHHHEEEEEEECCCCCCCCCCHHCCCCCEEEEEEECCCCCCCCCCHHHH
LIHGGLRYLEHYAFRLVREALAEREVLWGIAPHIIWPLRFVLPHHAGLRPAWMLRLGLFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
YDHLGGRRLLPPTRTLDLRHDPAGLPLRPGLGTAFEYSDCWVEDARLVVLNARDAADRGA
HHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCEECCCCEECCCEEEEEECCCCCCCCC
SIRPRTKVVGAHRVDGLWEIEAEGMAGRESVRARALVDAAGPWAGQVLDVLQVKASARLR
CCCCCHHEECCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEE
LVKGSHIVVHRLFAHDRCYLFQNGDGRIVFAIPYEGDFTLIGTTDLDYEGRPEDVAASPE
EEECCEEEEHHHHHCCEEEEEECCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCHH
EVAYLCAAASEYFAAALAPEQVVWAYSGVRALYDDGAGKAQEATRDYVLALDAPDGEAPL
HHHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHCCCCCCHHHCCCCEEEEEECCCCCCCC
LSVFGGKITTYRRLAEATLARLAPHLPVLGPSFTGKVPLPGGDFPRQGFDHLLKSLRRTF
HHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
PALDPALLKRLARAYGTSTFRLLEGVMHEDDLGDWFGAHLCRREVDWLMDQEWAMTAEDV
CCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHH
LWRRSKLGLRTRHEEARTLDAYMAARRGG
HHHHHHCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157588; 10984043 [H]