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The map label for this gene is cpx [H]

Identifier: 154246569

GI number: 154246569

Start: 2915730

End: 2917526

Strand: Direct

Name: cpx [H]

Synonym: Xaut_2628

Alternate gene names: 154246569

Gene position: 2915730-2917526 (Clockwise)

Preceding gene: 154246568

Following gene: 154246572

Centisome position: 54.92

GC content: 69.78

Gene sequence:

>1797_bases
ATGCTTGACGCCAAAGCGCGGTCACGGTCGCCGCGGTCCCATATCCGACGCGTGATCGAGCGCCTCTTTCCTGATCCGAG
ACGCGGCAGCCGCACCCTGCGTCGCCCGGCCTCCCTGGTCTACGGGCTCGACGACAAGGTGCCCCCGGTCGCGCTGGTGC
CGCTTGCCGCCCAGCACGCCATGCTGGCGGTCACCTTCCTGATCTATCCGGTGCTGGCGGCCACCGAGGCGCGGCTGCCG
GCGGACCAGATGTCCGCTATGCTCTCGGCCTGCGCTATGAGCATCGGCGTCGCCACCATCATCCAGTGCCTGCGCACGCG
CTTCGGCTCGGGCTATCTCGCCGTGCACATCCCGGCGCCGGGGGCCATTCCGCTCGCCGCCCAGGCGCTGATGCTCGGCG
GGCTCGGGCTGATGGCCATGACCACGCTGCTGGTGGGGATCTGCCAATTGTTCATGGCGCGCCTGGTGCGGCCGCTGCGG
GTGCTACTGCCGCCGGAAGTGTGCGGCGTGGCGGTGAGCATGCTCGGTGTGTCGCTGGCGGGGCCAGCCCTGCGCCGTGC
GCTGGGGCTCGACCACGGGCCGCTGGTGGTGCAGAACGCCACCTTCTCCAGCCTCGCCACCGTGGGCATCATCGTCGCCA
TCACCGTGTTCGCCCCCCGTCGGCTGAAGCTGTTCGCGGTGTTTGCCGGCGCTGGCATCGGCTGGGTGCTGGCGCTGCTG
CTCGGCGCGGGGCATCCGGAGGCGAACGCGGCCATCGCCGCCGCGCCCCTGGTCGCCTGGCCGACGCTGACGCTGCCCAG
CCTCCAGTTCGCCCCGGCGCTGTTTCCGTTGATGGCGCTGCTGGTTATGATGAATCTCGTGGACGTTCTCTCGGTCACCG
TCTCGCTGGAGAAGATGAACGATGCCGACTGGCGCCGCGCCGACATGCAGGCGGCCCAGAGGGCGGTGACTGCCTGCGGC
ATCGGCAACATCCTCAACGGGCTGACCTCCGGCTTCCAGTCGGGGCTGTCCTCCTCGTCGGTGGGGCTGGCCTTCGCCAC
CCAGTCCACGGCGCGCATCATCGGCATCCTCGCCGGTGCGATGATCTTCGCCATCGCCTTCCTGCCGAAGGCCATCGTGG
CGCTCACCCTCATCCCCTCGCCAGTGATCGGCGGCATCCTGCTCTACACCTCGGCCTATCTGGTGGTGGCGGGCATGGAT
CTCGTCACCTCGCGCCGCCTCAGCGAGCGGCGGGTGTTCGTGGTGGGGCTGTCGGTGCTGGCGGGGCTGTCGGTAGCCCT
CCTGCCGTTGCGAGACCAACTGCCGCTGGCGCTCCAGCCCCTGTTCTCCACGCCGCTCACGGTGGGGGCGCTCAGCGCCA
TCCTGCTGAATCTGCTGTTCCGCATCGGCATCGCTCGCGAGACCGGGGAGATCGTACCGGACGGGGCGCATGCCTTCCCA
TTCGCCCGCGACTTCCTGGAGCGGCAGGGCGATGTGTGGGGCGCGCGACGCGACGTGATCGCCGCCGCCATCCCCACGGT
GGCGCAGGCGCTGGAACTCGTCATCGACGCCGGCATCGCCGAGGGCCCCATCGAGCTGCGCGCGCGCTTCGACGAGACGC
ATCTCGACGTCTATCTCATCTATGACGGCGAGGTGGTAGAGGCGCCCAAGGAGCGGCCCTCGCCCGAGGCGCTGCTGGGC
GACGCGAAGGAACACGCCTCGTTCGCCGCCTGGATGCTCAAGCGCCTGTCCGACCACGTGCATTTCGGCCGCACCGGCGG
CGGCAAGGCGCGCATCGCCCTGAGCTTTGATCACTGA

Upstream 100 bases:

>100_bases
GCCGCCCTGATGCTTGCGCGCACTCATCCCGATGGCCTGTTCGTGCCGCCGCCCATCGCCATCGCCCATCACCTCGTCCG
GGCCTTCGTCGAAGGTATCG

Downstream 100 bases:

>100_bases
ACGGAGCGGCGCTCCGCCCGTTCAGAACGTCCGGATCAGACCGTCTCCTCAGAACGTTTCCTGCTCCGCCGCGAACTGCG
CCCGGTAGGGATGGGCGGGA

Product: xanthine/uracil/vitamin C permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 598; Mature: 598

Protein sequence:

>598_residues
MLDAKARSRSPRSHIRRVIERLFPDPRRGSRTLRRPASLVYGLDDKVPPVALVPLAAQHAMLAVTFLIYPVLAATEARLP
ADQMSAMLSACAMSIGVATIIQCLRTRFGSGYLAVHIPAPGAIPLAAQALMLGGLGLMAMTTLLVGICQLFMARLVRPLR
VLLPPEVCGVAVSMLGVSLAGPALRRALGLDHGPLVVQNATFSSLATVGIIVAITVFAPRRLKLFAVFAGAGIGWVLALL
LGAGHPEANAAIAAAPLVAWPTLTLPSLQFAPALFPLMALLVMMNLVDVLSVTVSLEKMNDADWRRADMQAAQRAVTACG
IGNILNGLTSGFQSGLSSSSVGLAFATQSTARIIGILAGAMIFAIAFLPKAIVALTLIPSPVIGGILLYTSAYLVVAGMD
LVTSRRLSERRVFVVGLSVLAGLSVALLPLRDQLPLALQPLFSTPLTVGALSAILLNLLFRIGIARETGEIVPDGAHAFP
FARDFLERQGDVWGARRDVIAAAIPTVAQALELVIDAGIAEGPIELRARFDETHLDVYLIYDGEVVEAPKERPSPEALLG
DAKEHASFAAWMLKRLSDHVHFGRTGGGKARIALSFDH

Sequences:

>Translated_598_residues
MLDAKARSRSPRSHIRRVIERLFPDPRRGSRTLRRPASLVYGLDDKVPPVALVPLAAQHAMLAVTFLIYPVLAATEARLP
ADQMSAMLSACAMSIGVATIIQCLRTRFGSGYLAVHIPAPGAIPLAAQALMLGGLGLMAMTTLLVGICQLFMARLVRPLR
VLLPPEVCGVAVSMLGVSLAGPALRRALGLDHGPLVVQNATFSSLATVGIIVAITVFAPRRLKLFAVFAGAGIGWVLALL
LGAGHPEANAAIAAAPLVAWPTLTLPSLQFAPALFPLMALLVMMNLVDVLSVTVSLEKMNDADWRRADMQAAQRAVTACG
IGNILNGLTSGFQSGLSSSSVGLAFATQSTARIIGILAGAMIFAIAFLPKAIVALTLIPSPVIGGILLYTSAYLVVAGMD
LVTSRRLSERRVFVVGLSVLAGLSVALLPLRDQLPLALQPLFSTPLTVGALSAILLNLLFRIGIARETGEIVPDGAHAFP
FARDFLERQGDVWGARRDVIAAAIPTVAQALELVIDAGIAEGPIELRARFDETHLDVYLIYDGEVVEAPKERPSPEALLG
DAKEHASFAAWMLKRLSDHVHFGRTGGGKARIALSFDH
>Mature_598_residues
MLDAKARSRSPRSHIRRVIERLFPDPRRGSRTLRRPASLVYGLDDKVPPVALVPLAAQHAMLAVTFLIYPVLAATEARLP
ADQMSAMLSACAMSIGVATIIQCLRTRFGSGYLAVHIPAPGAIPLAAQALMLGGLGLMAMTTLLVGICQLFMARLVRPLR
VLLPPEVCGVAVSMLGVSLAGPALRRALGLDHGPLVVQNATFSSLATVGIIVAITVFAPRRLKLFAVFAGAGIGWVLALL
LGAGHPEANAAIAAAPLVAWPTLTLPSLQFAPALFPLMALLVMMNLVDVLSVTVSLEKMNDADWRRADMQAAQRAVTACG
IGNILNGLTSGFQSGLSSSSVGLAFATQSTARIIGILAGAMIFAIAFLPKAIVALTLIPSPVIGGILLYTSAYLVVAGMD
LVTSRRLSERRVFVVGLSVLAGLSVALLPLRDQLPLALQPLFSTPLTVGALSAILLNLLFRIGIARETGEIVPDGAHAFP
FARDFLERQGDVWGARRDVIAAAIPTVAQALELVIDAGIAEGPIELRARFDETHLDVYLIYDGEVVEAPKERPSPEALLG
DAKEHASFAAWMLKRLSDHVHFGRTGGGKARIALSFDH

Specific function: Unknown

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082181, Length=444, Percent_Identity=23.8738738738739, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1790087, Length=452, Percent_Identity=25.2212389380531, Blast_Score=84, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017588
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 63232; Mature: 63232

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDAKARSRSPRSHIRRVIERLFPDPRRGSRTLRRPASLVYGLDDKVPPVALVPLAAQHA
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHCHHHHHCCCCCCCCCEEEHHHHHHHH
MLAVTFLIYPVLAATEARLPADQMSAMLSACAMSIGVATIIQCLRTRFGSGYLAVHIPAP
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
GAIPLAAQALMLGGLGLMAMTTLLVGICQLFMARLVRPLRVLLPPEVCGVAVSMLGVSLA
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
GPALRRALGLDHGPLVVQNATFSSLATVGIIVAITVFAPRRLKLFAVFAGAGIGWVLALL
CHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHH
LGAGHPEANAAIAAAPLVAWPTLTLPSLQFAPALFPLMALLVMMNLVDVLSVTVSLEKMN
HCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DADWRRADMQAAQRAVTACGIGNILNGLTSGFQSGLSSSSVGLAFATQSTARIIGILAGA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHH
MIFAIAFLPKAIVALTLIPSPVIGGILLYTSAYLVVAGMDLVTSRRLSERRVFVVGLSVL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEHHHH
AGLSVALLPLRDQLPLALQPLFSTPLTVGALSAILLNLLFRIGIARETGEIVPDGAHAFP
HCCHHEEECCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCH
FARDFLERQGDVWGARRDVIAAAIPTVAQALELVIDAGIAEGPIELRARFDETHLDVYLI
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEECCCCCEEEEEE
YDGEVVEAPKERPSPEALLGDAKEHASFAAWMLKRLSDHVHFGRTGGGKARIALSFDH
ECCCEECCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECC
>Mature Secondary Structure
MLDAKARSRSPRSHIRRVIERLFPDPRRGSRTLRRPASLVYGLDDKVPPVALVPLAAQHA
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHCHHHHHCCCCCCCCCEEEHHHHHHHH
MLAVTFLIYPVLAATEARLPADQMSAMLSACAMSIGVATIIQCLRTRFGSGYLAVHIPAP
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
GAIPLAAQALMLGGLGLMAMTTLLVGICQLFMARLVRPLRVLLPPEVCGVAVSMLGVSLA
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
GPALRRALGLDHGPLVVQNATFSSLATVGIIVAITVFAPRRLKLFAVFAGAGIGWVLALL
CHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHH
LGAGHPEANAAIAAAPLVAWPTLTLPSLQFAPALFPLMALLVMMNLVDVLSVTVSLEKMN
HCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DADWRRADMQAAQRAVTACGIGNILNGLTSGFQSGLSSSSVGLAFATQSTARIIGILAGA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHH
MIFAIAFLPKAIVALTLIPSPVIGGILLYTSAYLVVAGMDLVTSRRLSERRVFVVGLSVL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEHHHH
AGLSVALLPLRDQLPLALQPLFSTPLTVGALSAILLNLLFRIGIARETGEIVPDGAHAFP
HCCHHEEECCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCH
FARDFLERQGDVWGARRDVIAAAIPTVAQALELVIDAGIAEGPIELRARFDETHLDVYLI
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEECCCCCEEEEEE
YDGEVVEAPKERPSPEALLGDAKEHASFAAWMLKRLSDHVHFGRTGGGKARIALSFDH
ECCCEECCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11792842; 8162194 [H]